Refractory

Oncology·MeSH: Recurrence

329 drugs in development·140 companies·4 clinical trials

Drug Pipeline by Phase

Approved(38)

Drug	Company
alferon n	AIM ImmunoTech Inc. (AIM)
arsenic tri	NEXUS BIOPHARMA INC (NEXS)
aucatzyl	Autolus Therapeutics plc (AUTL)
azacitidine	Amneal Pharmaceuticals, Inc. (AMRX)
bexarotene	Amneal Pharmaceuticals, Inc. (AMRX)
bexarotene	ANI PHARMACEUTICALS INC (ANIP)
bortezomib	Teva Pharmaceutical Industries Limited (TEVA)
carmustine	Amneal Pharmaceuticals, Inc. (AMRX)
cibinqo	PFIZER INC (PFE)
clofarabine	Mersana Therapeutics, Inc. (MRSN)
clofarabine	DR REDDYS LABORATORIES LTD (RDY)
clopidogrel bi	Teva Pharmaceutical Industries Limited (TEVA)
danyelza	Y-mAbs Therapeutics, Inc. (YMAB)
GIAPREZA®	Innoviva, Inc. (INVA)
imatinib	Mylan II B.V. (MYL)
imatinib	Aptinyx Inc. (APTX)
imatinib	Teva Pharmaceutical Industries Limited (TEVA)
imatinib	SUNSET ISLAND GROUP (SUN)
imatinib	DR REDDYS LABORATORIES LTD (RDY)
imatinib	Amneal Pharmaceuticals, Inc. (AMRX)
imkeldi	CG Oncology, Inc. (CGON)
jaypirca	LOXO ONCOLOGY, INC. (LOXO)
Jaypirca	ELI LILLY & Co (LLY)
Jaypirca®	ELI LILLY & Co (LLY)
komzifti	Kura Oncology, Inc. (KURA)
LYMPHIR (denileukin diftitox-cdxl)	CITIUS ONCOLOGY, INC. (CTOR)
methotrexate	ELITE PHARMACEUTICALS INC /NV/ (ELTP)
Monjuvi	Xencor Inc (XNCR)
ojemda	Day One Biopharmaceuticals, Inc. (DAWN)
Revuforj	Syndax Pharmaceuticals Inc (SNDX)
rezlidhia	RIGEL PHARMACEUTICALS INC (RIGL)
solx gold shunt	SPOTLIGHT INNOVATION INC. (STLT)
tirofiban	NEXUS BIOPHARMA INC (NEXS)
Tyvyt	ELI LILLY & Co (LLY)
Tyvyt®	ELI LILLY & Co (LLY)
valrubicin	CG Oncology, Inc. (CGON)
vigabatrin	DR REDDYS LABORATORIES LTD (RDY)
xpovio	Karyopharm Therapeutics Inc. (KPTI)

Phase 3(59)

Drug	Company
alxn2075	ALEXION PHARMACEUTICALS, INC. (ALXN)
anitocabtagene autoleucel	GILEAD SCIENCES, INC. (GILD)
bb2121	CELGENE CORP /DE/ (CELG)
belumosudil	Sanofi (SNY)
bexobrutideg	Nurix Therapeutics, Inc. (NRIX)
Blinatumomab	ENANTA PHARMACEUTICALS INC (ENTA)
bortezomib	AbbVie Inc. (ABBV)
cabozantinib	GH Research PLC (GHRS)
CardiAMP®	BioCardia, Inc. (BCDA)
carfilzomib	Sanofi (SNY)
Carfilzomib	BRISTOL MYERS SQUIBB CO (BMY)
chemotherapy agents	Takeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock) (TAK)
chemotherapy agents	TAKEDA PHARMACEUTICAL CO LTD (TKPHF)
dabrafenib	GH Research PLC (GHRS)
daratumumab	ASTRAZENECA PLC (AZN)
daratumumab	REGENERON PHARMACEUTICALS, INC. (REGN)
daratumumab	Juno Therapeutics, Inc. (JUNO)
Daratumumab	BRISTOL MYERS SQUIBB CO (BMY)
descartes-15	Cartesian Therapeutics, Inc. (RNAC)
elotuzumab	REGENERON PHARMACEUTICALS, INC. (REGN)
hmpl-760	HUTCHMED (China) Ltd (HMDCF)
HMPL-760	ENANTA PHARMACEUTICALS INC (ENTA)
ima203 product	Immatics N.V. (IMTX)
ima203 product- flat dose	Immatics N.V. (IMTX)
ima203cd8 product	Immatics N.V. (IMTX)
Inotuzumab	ENANTA PHARMACEUTICALS INC (ENTA)
intrathecal chemotherapy	GH Research PLC (GHRS)
Isatuximab	Sanofi (SNY)
ixazomib	X4 Pharmaceuticals, Inc (XFOR)
kte-c19	Kite Pharma, Inc. (KITE)
liso-cel	CELGENE CORP /DE/ (CELG)
Liso-cel	BRISTOL MYERS SQUIBB CO (BMY)
Manufactured Anti-BCMA CAR-T cells	Filana Therapeutics Inc. (FLNA)
Mezigdomide	BRISTOL MYERS SQUIBB CO (BMY)
montelukast	Sanofi (SNY)
Montelukast	Sanofi (SNY)
obinutuzumab	GH Research PLC (GHRS)
obinutuzumab	BeOne Medicines Ltd. (ONC)
Obinutuzumab	BeOne Medicines Ltd. (ONC)
olverembatinib	CHINA PHARMA HOLDINGS, INC. (CPHI)
Orelabrutinib	Merus N.V. (MRUS)
Pomalidomide	BeOne Medicines Ltd. (ONC)
Pomalidomide	Merus N.V. (MRUS)
Pomalidomide	BRISTOL MYERS SQUIBB CO (BMY)
r-gemox	HUTCHMED (China) Ltd (HMDCF)
R-GemOx	ENANTA PHARMACEUTICALS INC (ENTA)
Rocbrutinib	Merus N.V. (MRUS)
Roginolisib	ENANTA PHARMACEUTICALS INC (ENTA)
sonrotoclax	BeOne Medicines Ltd. (ONC)
Sonrotoclax	ENANTA PHARMACEUTICALS INC (ENTA)
tak-007	TAKEDA PHARMACEUTICAL CO LTD (TKPHF)
teclistamab	GH Research PLC (GHRS)
Teclistamab	Merus N.V. (MRUS)
tirabrutinib	West Pharmaceutical Services Inc. (WST)
tirabrutinib	Eton Pharmaceuticals, Inc. (ETON)
tirabrutinib	Deciphera Pharmaceuticals, Inc. (DCPH)
trametinib	GH Research PLC (GHRS)
uproleselan	Apollomics Inc. (APLM)
Zanubrutinib	Merus N.V. (MRUS)

Phase 2(66)

Drug	Company
ALLO-501	Allogene Therapeutics, Inc. (ALLO)
ALLO-501A	Allogene Therapeutics, Inc. (ALLO)
ALLO-647	Allogene Therapeutics, Inc. (ALLO)
allo-715	Allogene Therapeutics, Inc. (ALLO)
allogeneic nk cells	Artiva Biotherapeutics, Inc. (ARTV)
allonk	Artiva Biotherapeutics, Inc. (ARTV)
AUCATZYL/obe-cel	Autolus Therapeutics plc (AUTL)
bendamustine	CELLULAR BIOMEDICINE GROUP, INC. (CMBG)
Bendamustine	FATE THERAPEUTICS INC (FATE)
Bortezomib	FATE THERAPEUTICS INC (FATE)
CAR BCMA-CD70-T cells	Filana Therapeutics Inc. (FLNA)
CAR BCMA-CD70-T cells	Merus N.V. (MRUS)
CD19t-haNK suspension	ImmunityBio, Inc. (IBRX)
Cemiplimab	Amneal Pharmaceuticals, Inc. (AMRX)
Clofarabine	Arbutus Biopharma Corp (ABUS)
Cyclophophamide	Allogene Therapeutics, Inc. (ALLO)
cyt-0851	Cyteir Therapeutics, Inc. (CYT)
diphenhydramine	Sanofi (SNYNF)
Elraglusib Injection	ACTUATE THERAPEUTICS, INC. (ACTU)
Elraglusib Oral Tablet	ACTUATE THERAPEUTICS, INC. (ACTU)
EOS-448	iTeos Therapeutics, Inc. (ITOS)
Fludarabine	FATE THERAPEUTICS INC (FATE)
Fludarabine	Allogene Therapeutics, Inc. (ALLO)
GM-CSF	UNITED THERAPEUTICS Corp (UTHR)
golcadomide	GH Research PLC (GHRS)
haNK	ImmunityBio, Inc. (IBRX)
hu14.18K322A	Black Diamond Therapeutics, Inc. (BDTX)
hu14.18K322A	Filana Therapeutics Inc. (FLNA)
hu14.18K322A	PTC THERAPEUTICS, INC. (PTCT)
iberdomide	CELGENE CORP /DE/ (CELG)
impt-314	Lyell Immunopharma, Inc. (LYEL)
incb001158	Incyte Corp. (INCY)
Inotuzumab ozogamicin	ENANTA PHARMACEUTICALS INC (ENTA)
intranasal epinephrine technology product candidates	ARS Pharmaceuticals, Inc. (SPRY)
isatuximab	Sanofi (SNY)
isatuximab sc-obds	Sanofi (SNY)
Loncastuximab tesirine	ENANTA PHARMACEUTICALS INC (ENTA)
Mivavotinib (CB-659)	Calithera Biosciences, Inc. (CALA)
N803	Black Diamond Therapeutics, Inc. (BDTX)
N803	Filana Therapeutics Inc. (FLNA)
N803	PTC THERAPEUTICS, INC. (PTCT)
n803 plus bacillus calmette-guerin	ImmunityBio, Inc. (IBRX)
nal er	Trevi Therapeutics, Inc. (TRVI)
nexi-002	NexImmune, Inc. (NEXI)
NK Cells	Filana Therapeutics Inc. (FLNA)
Obe-cel (AUTO1)	Autolus Therapeutics plc (AUTL)
Part 1	FATE THERAPEUTICS INC (FATE)
Part 2	FATE THERAPEUTICS INC (FATE)
Pirtobrutinib	Filana Therapeutics Inc. (FLNA)
Pirtobrutinib	ENANTA PHARMACEUTICALS INC (ENTA)
PYX-107	Pyxis Oncology, Inc. (PYXS)
r-gemox	HUTCHMED (China) Limited (HCM)
revumenib	GH Research PLC (GHRS)
rls-0071	CV Sciences, Inc. (CVSI)
rtx-224	Rubius Therapeutics, Inc. (RUBY)
rtx-240	Rubius Therapeutics, Inc. (RUBY)
sar446523	Sanofi (SNYNF)
Sargramostim	PTC THERAPEUTICS, INC. (PTCT)
Selinexor	FATE THERAPEUTICS INC (FATE)
sl-701	STEMLINE THERAPEUTICS INC (STML)
t-haNK	ImmunityBio, Inc. (IBRX)
trichostatin a	Vanda Pharmaceuticals Inc. (VNDA)
UCART123v1.2	Cellectis S.A. (CLLS)
vcar33	Vor Biopharma Inc. (VOR)
vidutolimod	CHECKMATE PHARMACEUTICALS, INC. (CMPI)
Zanubrutinib	ENANTA PHARMACEUTICALS INC (ENTA)

Phase 1(98)

Drug	Company
[14C]ABT-199	AbbVie Inc. (ABBV)
ABT-199	AbbVie Inc. (ABBV)
ACLX-001	Arcellx, Inc. (ACLX)
ACLX-002	Arcellx, Inc. (ACLX)
ADCLEC.syn1 CAR T cells	Merus N.V. (MRUS)
ADCT-602	ADC Therapeutics SA (ADCT)
apg-3288	ASCENTAGE PHARMA GROUP INTERNATIONAL (AAPG)
ARV-393	ARVINAS, INC. (ARVN)
ATA3219	Atara Biotherapeutics, Inc. (ATRA)
AUTO6NG	Autolus Therapeutics plc (AUTL)
Autologous CCR4 CAR T cells	Merus N.V. (MRUS)
Autologous CCR4 CAR T cells	Filana Therapeutics Inc. (FLNA)
B7-H3-CAR T Cells	Merus N.V. (MRUS)
BET Bromodomain Inhibitor ZEN-3694	Amneal Pharmaceuticals, Inc. (AMRX)
bms-986515	Juno Therapeutics, Inc. (JUNO)
BP1002	BIO-PATH HOLDINGS, INC. (BPTH)
Carfilzomib	Merus N.V. (MRUS)
CB-010	Caribou Biosciences, Inc. (CRBU)
CB-011	Caribou Biosciences, Inc. (CRBU)
CB-012	Caribou Biosciences, Inc. (CRBU)
cd19 t-hank	ImmunityBio, Inc. (IBRX)
cd19t-hank	ImmunityBio, Inc. (IBRX)
CD371-specific/YSNVz/I-18 CAR T cells	Merus N.V. (MRUS)
CLN-049	Cullinan Therapeutics, Inc. (CGEM)
CLN-619	Cullinan Therapeutics, Inc. (CGEM)
CTX340	CRISPR Therapeutics AG (CRSP)
Cytarabine	Syndax Pharmaceuticals Inc (SNDX)
diphenhydramine	Sanofi (SNY)
Dual-Target Antigen-Selected CAR-NK	Filana Therapeutics Inc. (FLNA)
DVX201 (Unmodified Natural Killer Cells)	Coeptis Therapeutics Holdings Inc. (COEP)
E7777 (LYMPHIR) prior to CAR-T	CITIUS ONCOLOGY, INC. (CTOR)
EB-SELECT Single-Target CAR-NK Cells	Filana Therapeutics Inc. (FLNA)
Efbalropendekin alfa (XmAb306 / RG6323)	Xencor Inc (XNCR)
Encorafenib	ENANTA PHARMACEUTICALS INC (ENTA)
epcoritamab	Genmab A/S (GMAB)
Epcoritamab	ENANTA PHARMACEUTICALS INC (ENTA)
Epcoritamab	Filana Therapeutics Inc. (FLNA)
Epcoritamab	ELI LILLY & Co (LLY)
EXS73565	RECURSION PHARMACEUTICALS, INC. (RXRX)
ezm0414	Epizyme, Inc. (EPZM)
fludarabine	CELLULAR BIOMEDICINE GROUP, INC. (CMBG)
fludarabine	Juno Therapeutics, Inc. (JUNO)
Fludarabine	ImmunityBio, Inc. (IBRX)
Fludarabine	NEKTAR THERAPEUTICS (NKTR)
FT522	FATE THERAPEUTICS INC (FATE)
gtb-3650	GT Biopharma, Inc. (GTBP)
hec89736	SUNSHINE BIOPHARMA INC. (SBFM)
Hyper-CVAD	ENANTA PHARMACEUTICALS INC (ENTA)
Hyper-CVAD	Merus N.V. (MRUS)
ima 401	Immatics N.V. (IMTX)
ima401	Immatics N.V. (IMTX)
Imetelstat	Assertio Holdings, Inc. (ASRT)
jnj-79635322	GH Research PLC (GHRS)
jnj-87562761	GH Research PLC (GHRS)
jnj-90009530	GH Research PLC (GHRS)
KT-253	Kymera Therapeutics, Inc. (KYMR)
KT-333	Kymera Therapeutics, Inc. (KYMR)
kur-501	Athenex, Inc. (ATNX)
LCAR-AIO T cells	Legend Biotech Corp (LEGN)
lisaftoclax	ASCENTAGE PHARMA GROUP INTERNATIONAL (AAPG)
LUCAR-DKS1 NK cells	Legend Biotech Corp (LEGN)
LUCAR-G79 T cells	Legend Biotech Corp (LEGN)
LYMPHIR (investigator-initiated: pre-CAR-T)	CITIUS ONCOLOGY, INC. (CTOR)
mb-101	Fortress Biotech Inc. (FBIO)
mb-101	MUSTANG BIO, INC. (MBIO)
mb-109	MUSTANG BIO, INC. (MBIO)
Mini-hyper-CVD	ENANTA PHARMACEUTICALS INC (ENTA)
Mini-hyper-CVD	Merus N.V. (MRUS)
mk-4002	Merck & Co., Inc. (MRK)
mt-6402	Molecular Templates, Inc. (MTEM)
N803	ImmunityBio, Inc. (IBRX)
nc525	NextCure, Inc. (NXTC)
nirogacestat	Allogene Therapeutics, Inc. (ALLO)
nxc-201	Immix Biopharma, Inc. (IMMX)
olverembatinib	ASCENTAGE PHARMA GROUP INTERNATIONAL (AAPG)
Revumenib	Syndax Pharmaceuticals Inc (SNDX)
RP3	Replimune Group, Inc. (REPL)
sar439459	Sanofi (SNY)
sar445514	Sanofi (SNYNF)
sar445514	Sanofi (SNY)
sar446523	Sanofi (SNY)
sc-daric33	2seventy bio, Inc. (TSVT)
sgr-1505	Schrodinger, Inc. (SDGR)
sgr-2921	Schrodinger, Inc. (SDGR)
sti-1492	Sorrento Therapeutics, Inc. (SRNE)
tak-573	Teva Pharmaceutical Industries Limited (TEVA)
tazemetostat	Epizyme, Inc. (EPZM)
Tazemetostat	Merus N.V. (MRUS)
tocilizumab	Juno Therapeutics, Inc. (JUNO)
tti-621	Trillium Therapeutics Inc. (TRIL)
tti-622	Trillium Therapeutics Inc. (TRIL)
vir-5500	Vir Biotechnology, Inc. (VIR)
VIR-5500	KYNTRA BIO INC. (KYNB)
vispa-cel	Caribou Biosciences, Inc. (CRBU)
wtx-712	Werewolf Therapeutics, Inc. (HOWL)
zamtocabtagene autoleucel	CELLULAR BIOMEDICINE GROUP, INC. (CMBG)
zelebrudomide	Nurix Therapeutics, Inc. (NRIX)
ZN-d5	Zentalis Pharmaceuticals, Inc. (ZNTL)

Preclinical(10)

Drug	Company
ACLX-004	Arcellx, Inc. (ACLX)
al101	OLD AYALA, INC (AYLA)
BCR-ABL TKI	Theseus Pharmaceuticals, Inc. (THRX)
BP1003	BIO-PATH HOLDINGS, INC. (BPTH)
cannabidophorol pro	INNOVATION1 BIOTECH INC. (GMVP)
CBS104	Harmony Biosciences Holdings, Inc. (HRMY)
neo-ptc-01	Neon Therapeutics, Inc. (NTGN)
parenteral-delivered formulations	NEXIEN BIOPHARMA, INC. (NXEN)
rasp-301	ACTAVIA LIFE SCIENCES, INC. (RASP)
tetra-specific antibody	OPKO HEALTH, INC. (OPK)

Unknown(3)

Drug	Company
LCAR- F33S cells intravenous infusion	Legend Biotech Corp (LEGN)
puzolcabtagene autoleucel	PRECISION BIOSCIENCES INC (DTIL)
uproleselan	CRESCENT BIOPHARMA, INC. (CBIO)

Early Phase 1(1)

Drug	Company
Lidocaine and Ketamine Infusion	Crinetics Pharmaceuticals, Inc. (CRNX)

Phase 1/Phase 2(37)

Drug	Company
abexinostat	XYNOMIC PHARMACEUTICALS HOLDINGS, INC. (BCACU)
amt-260	uniQure N.V. (QURE)
auto1	Autolus Therapeutics plc (AUTL)
AUTO1/22	Autolus Therapeutics plc (AUTL)
belantamab mafodotin	Sanofi (SNYNF)
belantamab mafodotin	Sanofi (SNY)
bendamustine	Karyopharm Therapeutics Inc. (KPTI)
Carfilzomib	BeOne Medicines Ltd. (ONC)
daratumumab	BeOne Medicines Ltd. (ONC)
daratumumab	Genmab A/S (GMAB)
daratumumab	GENMAB A/S (GNMSF)
Daratumumab	BeOne Medicines Ltd. (ONC)
daratumumab sc	Incyte Corp. (INCY)
evorpacept	Sanofi (SNY)
evorpacept	Sanofi (SNYNF)
Fimepinostat	CURIS INC (CRIS)
gc012f	SQZ Biotechnologies Co (SQZB)
gen3014	GENMAB A/S (GNMSF)
gen3014	Genmab A/S (GMAB)
glpg5101	Galapagos NV (GLPG)
GLPG5101	Galapagos NV (GLPG)
l-nmma	Galera Therapeutics, Inc. (GRTX)
linvoseltamab	REGENERON PHARMACEUTICALS, INC. (REGN)
lisaftoclax	CHINA PHARMA HOLDINGS, INC. (CPHI)
Mosunetuzumab	BRISTOL MYERS SQUIBB CO (BMY)
nkx101	Nkarta, Inc. (NKTX)
onct-808	Oncternal Therapeutics, Inc. (ONCT)
pegenzileukin	Sanofi (SNYNF)
pegenzileukin	Sanofi (SNY)
polatuzumab vedotin	Karyopharm Therapeutics Inc. (KPTI)
reduced-dose hht	ASCENTAGE PHARMA GROUP INTERNATIONAL (AAPG)
regn17372+linvoseltamab	REGENERON PHARMACEUTICALS, INC. (REGN)
regn7945+linvoseltamab	REGENERON PHARMACEUTICALS, INC. (REGN)
sar439459	Sanofi (SNYNF)
standard-dose hht	ASCENTAGE PHARMA GROUP INTERNATIONAL (AAPG)
tafasitamab	Karyopharm Therapeutics Inc. (KPTI)
zugo-cel	CRISPR Therapeutics AG (CRSP)

Phase 2/Phase 3(5)

Drug	Company
bedaquiline	NYMOX PHARMACEUTICAL CORP (NYMXF)
ethambutol	NYMOX PHARMACEUTICAL CORP (NYMXF)
kyv-101	Kyverna Therapeutics, Inc. (KYTX)
rifampicin	NYMOX PHARMACEUTICAL CORP (NYMXF)
tak-007	Takeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock) (TAK)

Phase 4(12)

Drug	Company
Acalabrutinib	ASTRAZENECA PLC (AZN)
Belumosudil	Sanofi (SNY)
Belumosudil mesylate	Sanofi (SNY)
bms-986369	BRISTOL MYERS SQUIBB CO (BMY)
BMS-986393	BRISTOL MYERS SQUIBB CO (BMY)
BMS-986458	BRISTOL MYERS SQUIBB CO (BMY)
BMS-986525	BRISTOL MYERS SQUIBB CO (BMY)
ixazomib	TAKEDA PHARMACEUTICAL CO LTD (TKPHF)
mRNA-2808	Moderna, Inc. (MRNA)
Tislelizumab	ENANTA PHARMACEUTICALS INC (ENTA)
tocilizumab	REGENERON PHARMACEUTICALS, INC. (REGN)
Zanubrutinib	BeOne Medicines Ltd. (ONC)

Compare drugs

alferon n vs arsenic tri alferon n vs aucatzyl alferon n vs azacitidine

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BioSniper tracks 329 drugs in development for Refractory across 140 companies.

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There are 4 clinical trials targeting Refractory tracked by BioSniper.

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