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sargramostim

Generic: sargramostim·Brand: Leukine

sargramostim: 10 clinical trials tracked.

sargramostim evidence translation

What we can confirm

10 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about sargramostim, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence6 indications · 4 study sponsors
Clinical Trials (10)

Evaluating the Feasibility of a Survivin Peptide Vaccine (SurVaxM) as an Interception Agent in Patients at High Risk for Lung Cancer

NCT07169617·Phase 2·FLNA
Not yet recruiting

Primary endpoint: Seroconversion rate

Interventionalopen80 targetStarted 2026-02Completion 2027-094 sites · United StatesNational Cancer Institute (NCI)

A Phase II Study With a Safety Run-In of the Addition of N-803, a Novel IL-15 Super-Agonist, to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

NCT07085338·Phase 2·GHRS
Recruiting

Primary endpoint: To evaluate if the administration of N-803 in combination with irinotecan, temozolomide, hu14-18K322A, and GM-CSF in patients with relapsed/refractory neuroblastoma is feasible

InterventionalRandomizedopen54 targetStarted 2025-11Completion 2029-025 sites · United StatesSt. Jude Children's Research Hospital

N10: Reduced Therapy for High-Risk Neuroblastoma

NCT06528496·Phase 2·FLNA
Recruiting

Primary endpoint: Evaluate participant response

Interventionalopen45 targetStarted 2024-07Completion 2029-071 site · United StatesMemorial Sloan Kettering Cancer Center

A Phase II Randomized Study of Safety and Efficacy of a Multiple Antigen Vaccine (STEMVAC) in Non-Small-Cell Lung Cancer Patients

NCT05242965·Phase 2
Recruiting

Primary endpoint: CD8 is Reported as a Fraction of CD3+ Tumor Infiltrating Lymphocytes (TIL) in 4 High-power Field (HPF)

InterventionalRandomizeddouble40 targetStarted 2023-03Completion 2032-112 sites · United StatesUniversity of Washington

A Phase 2 Randomized Study of Irinotecan/Temozolomide/Dinutuximab With or Without Eflornithine (DFMO) in Children With Relapsed, Refractory or Progressive Neuroblastoma

NCT03794349·Phase 2·BDTX
Active, not recruiting

Primary endpoint: Response Rate

InterventionalRandomizedopen94 targetStarted 2019-07Completion 2029-0350 sites · United StatesChildren's Oncology Group

A Phase I Study of 131I-MIBG With Dinutuximab +/- Vorinostat for Relapsed/Refractory Neuroblastoma

NCT03332667·Phase 1·UTHR
Completed

Primary endpoint: MTD/RP2D Determination Cohort A

Interventionalopen45 enrolledStarted 2018-09Completion 2024-0212 sites · United StatesNew Approaches to Neuroblastoma Therapy Consortium

A Phase 3 Study of 131I-Metaiodobenzylguanidine (131I-MIBG) or ALK Inhibitor Therapy Added to Intensive Therapy for Children With Newly Diagnosed High-Risk Neuroblastoma (NBL)

NCT03126916·Phase 3
Recruiting

Primary endpoint: Event free survival (EFS) (Arm A, B, D, and E)

InterventionalRandomizedopen750 targetStarted 2018-05Completion 2030-0950 sites · United StatesChildren's Oncology Group

Double Blind, Parallel Groups, Controlled, Randomized Phase II Trial to Evaluate Vaccination With Folate Receptor Alpha Peptide Vaccine With GM-CSF as Vaccine Adjuvant Following Oral Cyclophosphamide Versus GM-CSF/Placebo to Prevent Recurrence in Patients With Triple Negative Breast Cancer

NCT03012100·Phase 2
Active, not recruiting
InterventionalRandomizedtriple280 targetStarted 2017-03Completion 2026-0712 sites · United StatesAcademic and Community Cancer Research United

Randomized Phase II/III Study of Nivolumab Plus Ipilimumab Plus Sargramostim Versus Nivolumab Plus Ipilimumab in Patients With Unresectable Stage III or Stage IV Melanoma

NCT02339571·Phase 2·FLNA
Active, not recruiting

Primary endpoint: Overall survival

InterventionalRandomizedopen600 targetStarted 2015-11Completion 2033-0650 sites · United StatesNational Cancer Institute (NCI)

A Phase II Study of the Safety and Efficacy of SVN53-67/M57-KLH (SurVaxM) in Survivin-Positive Newly Diagnosed Glioblastoma

NCT02455557·Phase 2·BDTX
Active, not recruiting

Primary endpoint: Progression-free Survival (PFS)

Interventionalopen66 targetStarted 2015-05Completion 2026-035 sites · United StatesRoswell Park Cancer Institute