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vorinostat

Generic: VORINOSTAT·Brand: ZOLINZA, Zolinza

vorinostat: 14 clinical trials tracked.

vorinostat evidence translation

What we can confirm

14 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about vorinostat, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence5 indications · 5 study sponsors
Clinical Trials (14)showing 10 most recent

NANT 2021-02: A Randomized Phase 2 Study of 131I-MIBG With Vorinostat VS. 131I-MIBG With Dinutuximab vs. 131I-MIBG With Dinutuximab and Vorinostat for Relapsed or Refractory Neuroblastoma

NCT07261241·Phase 2
Not yet recruiting

Primary endpoint: Objective Tumor Response After One Course of Therapy

InterventionalRandomizedopen118 targetStarted 2026-12Completion 2031-1213 sites · United StatesNew Approaches to Neuroblastoma Therapy Consortium

Use of Vorinostat as GVHD Prophylaxis in Children, Adolescents, and Young Adults With Non-Malignant Disorders Undergoing Allogeneic Blood and Marrow Transplantation

NCT06995521·Phase 2·FLNA
Not yet recruiting

Primary endpoint: GVHD-free relapse-free Survival

Interventionalopen55 targetStarted 2026-03Completion 2028-061 site · United StatesSung Won Choi

IGHID 12430 - Deliver-02 - A Phase 1, Open Label, Randomized Study To Evaluate The Safety And Tolerability Of MGD014 And MGD020 With A Latency Reversal Agent Versus Temporary Treatment Interruption In Persons With HIV-1 On Antiretroviral Therapy

NCT07217379·Phase 1
Suspended

Primary endpoint: Percent of Participants Experiencing At Least One Grade 3 or Greater Adverse Event that are Possibly or Definitely Related to Study Treatment

InterventionalRandomizedopen24 targetStarted 2025-10Completion 2027-023 sites · Kenya, United StatesUniversity of North Carolina, Chapel Hill

Vorinostat to Augment Response to 177Lutetium-PSMA-617 in the Treatment of Patients With PSMA-Low Metastatic Castration-Resistant Prostate Cancer

NCT06145633·Phase 2
Recruiting

Primary endpoint: Proportion of patients who convert from prostate-specific membrane antigen (PSMA) low to PSMA high

Interventionalopen15 targetStarted 2024-09Completion 2027-121 site · United StatesFred Hutchinson Cancer Center

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

NCT05848687·Phase 1/Phase 2
Recruiting

Primary endpoint: Minimal Residual Disease

Interventionalopen90 targetStarted 2023-11Completion 2033-1224 sites · Canada, United StatesTanja Andrea Gruber

Multicenter Phase I/Ib Trial of Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer

NCT03742245·Phase 1
Active, not recruiting

Primary endpoint: MTD

Interventionalopen28 targetStarted 2019-06Completion 2026-121 site · United StatesThe Methodist Hospital Research Institute

A Phase I Study of 131I-MIBG With Dinutuximab +/- Vorinostat for Relapsed/Refractory Neuroblastoma

NCT03332667·Phase 1·UTHR
Completed

Primary endpoint: MTD/RP2D Determination Cohort A

Interventionalopen45 enrolledStarted 2018-09Completion 2024-0212 sites · United StatesNew Approaches to Neuroblastoma Therapy Consortium

A Phase 1 Study of Pembrolizumab Plus Vorinostat for Relapsed or Refractory Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, and Hodgkin Lymphoma

NCT03150329·Phase 1
Active, not recruiting

Primary endpoint: Number of Patients With Grade 3-5 Adverse Events

Interventionalopen52 enrolledStarted 2017-07Completion 2027-061 site · United StatesCity of Hope Medical Center

Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

NCT03117751·Phase 2/Phase 3
Active, not recruiting

Primary endpoint: Event-free survival of ALL patients (EFS)

InterventionalRandomizedsingle790 targetStarted 2017-03Completion 2028-098 sites · Australia, United StatesSt. Jude Children's Research Hospital

Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I

NCT02553460·Phase 1/Phase 2·GHRS
Active, not recruiting

Primary endpoint: Percentage of Treatment-related Mortality (TRM)

Interventionalopen50 targetStarted 2016-01Completion 2031-1015 sites · Canada, United StatesSt. Jude Children's Research Hospital