| ELI LILLY & CoLLY | Oncology, Neurology, Immunology, Ophthalmology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Pain, Dermatology, Hematology, Nephrology, Musculoskeletal, Gastroenterology, Endocrinology, Psychiatry | 7.2 | $1.00T | Commercial | — |
| JOHNSON & JOHNSONJNJ | Oncology, Neurology, Immunology, Ophthalmology, Respiratory, Pain, Dermatology, Gastroenterology, Psychiatry | 7.0 | $647.83B | Commercial | — |
| AbbVie Inc.ABBV | Oncology, Rare Disease, Gene Therapy, Neurology, Immunology, Ophthalmology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Pain, Dermatology, Hematology, Nephrology, Musculoskeletal, Gastroenterology, Endocrinology, Reproductive, Psychiatry | 7.6 | $439.62B | Commercial | — |
| Merck & Co., Inc.MRK | Oncology, Rare Disease, Immunology, Ophthalmology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Dermatology, Hematology, Nephrology, Musculoskeletal, Gastroenterology, Reproductive | 4.33/6 | $366.28B | Commercial | NYSE |
| Novartis AGNVS | Oncology, Rare Disease, Gene Therapy, Neurology, Immunology, Ophthalmology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Dermatology, Hematology, Nephrology, Musculoskeletal, Gastroenterology, Endocrinology, Reproductive, Psychiatry | 9.0 | $261.73B | Commercial | — |
| ASTRAZENECA PLCAZN | Oncology, Rare Disease, Gene Therapy, Neurology, Immunology, Ophthalmology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Pain, Dermatology, Hematology, Nephrology, Musculoskeletal, Gastroenterology, Endocrinology, Reproductive | 8.1 | $248.20B | Commercial | — |
| AMGEN INCAMGN | Oncology, Gene Therapy, Neurology, Immunology, Ophthalmology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Pain, Dermatology, Hematology, Nephrology, Musculoskeletal, Gastroenterology, Endocrinology, Reproductive | 6.2 | $206.25B | Commercial | Nasdaq |
| ABBOTT LABORATORIESABT | Oncology, Neurology, Immunology, Ophthalmology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Dermatology | 9.1 | $184.51B | Commercial | — |
| GILEAD SCIENCES, INC.GILD | Oncology, Immunology, Infectious Disease, Metabolic, Respiratory, Dermatology, Gastroenterology | 6.0 | $180.82B | Commercial | — |
| Novo Nordisk A/SNVO | Oncology, Rare Disease, Neurology, Ophthalmology, Cardiovascular, Infectious Disease, Metabolic, Pain, Dermatology, Hematology, Nephrology, Musculoskeletal, Gastroenterology, Endocrinology, Reproductive | 8.23/6 | $168.54B | Commercial | — |
| PFIZER INCPFE | Oncology, Rare Disease, Neurology, Immunology, Ophthalmology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Pain, Dermatology, Hematology, Nephrology, Musculoskeletal, Gastroenterology, Endocrinology | 9.2 | $158.39B | Commercial | — |
| BRISTOL MYERS SQUIBB COBMY | Oncology, Rare Disease, Gene Therapy, Neurology, Immunology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Pain, Dermatology, Hematology, Nephrology, Musculoskeletal, Psychiatry | 8.0 | $132.14B | Commercial | — |
| VERTEX PHARMACEUTICALS INC / MAVRTX | Oncology, Rare Disease, Gene Therapy, Neurology, Immunology, Metabolic, Respiratory, Pain, Hematology, Nephrology, Reproductive | 7.9 | $130.36B | Commercial | — |
| SanofiSNY | Oncology, Rare Disease, Gene Therapy, Neurology, Immunology, Ophthalmology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Pain, Dermatology, Hematology, Nephrology, Musculoskeletal, Gastroenterology, Endocrinology, Reproductive | 8.83/6 | $109.86B | Commercial | — |
| GSK plc American Depositary Shares (Each representing two Ordinary Shares)GSK | Oncology | — | $94.23B | Phase 3 | NYSE |
| REGENERON PHARMACEUTICALS, INC.REGN | Oncology, Rare Disease, Gene Therapy, Neurology, Immunology, Ophthalmology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Dermatology, Hematology, Nephrology, Gastroenterology | 7.0 | $81.72B | Commercial | — |
| ARGENX SEARGX | Oncology, Neurology, Immunology, Ophthalmology, Pain, Dermatology, Hematology, Nephrology, Endocrinology | 6.32/6 | $63.00B | Commercial | — |
| Takeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock)TAK | Oncology, Rare Disease, Neurology, Immunology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Pain, Dermatology, Hematology, Nephrology, Gastroenterology, Endocrinology, Reproductive, Psychiatry | 1.52/6 | $59.38B | Commercial | — |
| Moderna, Inc.MRNA | Oncology, Neurology, Immunology, Infectious Disease, Respiratory, Dermatology | 4.62/6 | $58.56B | Commercial | — |
| Cardinal Health Inc.CAH | Oncology, Musculoskeletal | 3.5 | $55.83B | Commercial | — |
| REVOLUTION MEDICINES, INC.RVMD | Oncology, Gastroenterology | 5.9 | $43.96B | Commercial | Nasdaq |
| Teva Pharmaceutical Industries LimitedTEVA | Oncology, Rare Disease, Neurology, Immunology, Metabolic, Respiratory, Pain, Dermatology | 6.2 | $42.73B | Commercial | — |
| BeOne Medicines Ltd.ONC | Oncology, Immunology, Dermatology, Nephrology, Musculoskeletal | 5.8 | $40.03B | Commercial | — |
| Royalty Pharma plcRPRX | Oncology, Neurology, Immunology, Infectious Disease, Metabolic, Dermatology, Nephrology, Endocrinology | 2.83/6 | $35.01B | Commercial | — |
| ALNYLAM PHARMACEUTICALS, INC.ALNY | Oncology, Rare Disease, Neurology, Cardiovascular, Metabolic, Dermatology, Hematology | 4.83/6 | $33.09B | Commercial | Nasdaq |
| BIOGEN INC.BIIB | Oncology, Rare Disease, Gene Therapy, Neurology, Immunology, Ophthalmology, Infectious Disease, Pain, Dermatology, Nephrology | 8.7 | $31.40B | Commercial | Nasdaq |
| Roivant Sciences Ltd.ROIV | Neurology, Immunology, Cardiovascular, Respiratory, Dermatology, Musculoskeletal | 6.6 | $29.63B | Phase 2 | Nasdaq |
| BeOne Medicines Ltd.BEIGF | Oncology, Immunology, Dermatology | — | $29.60B | Commercial | — |
| GE HealthCare Technologies Inc.GEHC | Oncology, Neurology, Cardiovascular | 8.7 | $28.88B | Commercial | — |
| Zoetis Inc.ZTS | Pharmaceutical preparations | 7.32/6 | $28.80B | No disclosed pipeline | NYSE |
| INSMED IncINSM | Oncology, Rare Disease, Neurology, Immunology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Dermatology, Nephrology, Gastroenterology, Endocrinology | 5.13/6 | $27.27B | Commercial | — |
| BioNTech SEBNTX | Oncology, Gene Therapy, Immunology, Infectious Disease, Respiratory | — | $24.78B | Commercial | — |
| Incyte Corp.INCY | Oncology, Immunology, Infectious Disease, Metabolic, Respiratory, Dermatology, Hematology, Nephrology, Gastroenterology | 8.0 | $24.68B | Commercial | Nasdaq |
| UNITED THERAPEUTICS CorpUTHR | Oncology, Rare Disease, Gene Therapy, Neurology, Immunology, Ophthalmology, Cardiovascular, Infectious Disease, Metabolic, Respiratory, Pain, Dermatology, Hematology, Nephrology, Musculoskeletal, Gastroenterology, Endocrinology, Reproductive, Psychiatry | 7.5 | $21.36B | Commercial | Nasdaq |
| Genmab A/SGMAB | Oncology, Immunology, Nephrology | — | $20.02B | Phase 3 | Nasdaq |
| Viatris IncVTRS | Oncology, Neurology, Immunology, Ophthalmology, Cardiovascular, Metabolic, Respiratory, Pain, Dermatology, Nephrology, Reproductive, Psychiatry | 8.9 | $19.08B | Commercial | Nasdaq |
| Zimmer Biomet Holdings Inc.ZBH | Oncology, Neurology, Immunology, Ophthalmology, Infectious Disease, Pain, Dermatology, Musculoskeletal | 8.1 | $18.46B | Commercial | — |
| Ascendis Pharma A/SASND | Oncology, Rare Disease, Dermatology, Endocrinology | 7.5 | $17.33B | Commercial | — |
| NEUROCRINE BIOSCIENCES INCNBIX | Oncology, Rare Disease, Neurology, Metabolic, Dermatology, Nephrology, Endocrinology, Psychiatry | 6.3 | $15.98B | Commercial | Nasdaq |
| Jazz Pharmaceuticals plcJAZZ | Oncology, Rare Disease, Neurology, Metabolic, Gastroenterology, Endocrinology, Psychiatry | 7.4 | $15.58B | Commercial | — |
| Summit Therapeutics Inc.SMMT | Oncology, Rare Disease, Neurology, Immunology, Cardiovascular, Infectious Disease, Reproductive | 7.1 | $14.69B | Phase 3 | Nasdaq |
| BridgeBio Pharma, Inc.BBIO | Oncology, Rare Disease, Cardiovascular | 2.73/6 | $14.62B | Commercial | — |
| EXELIXIS, INC.EXEL | Oncology, Immunology, Dermatology, Nephrology, Endocrinology | 7.2 | $13.93B | Commercial | Nasdaq |
| BIOMARIN PHARMACEUTICAL INCBMRN | Oncology, Rare Disease, Gene Therapy, Immunology, Dermatology, Hematology, Endocrinology | 6.52/6 | $12.75B | Commercial | — |
| CORCEPT THERAPEUTICS INCCORT | Oncology, Neurology, Cardiovascular, Infectious Disease, Metabolic, Nephrology, Gastroenterology, Endocrinology | 5.0 | $12.37B | Commercial | — |
| MADRIGAL PHARMACEUTICALS, INC.MDGL | Cardiovascular, Infectious Disease, Metabolic, Nephrology, Gastroenterology | 5.0 | $12.34B | Commercial | Nasdaq |
| HALOZYME THERAPEUTICS, INC.HALO | Endocrinology | 4.0 | $12.17B | Commercial | — |
| Baxter International Inc.BAX | Oncology, Reproductive | 8.03/6 | $12.06B | Commercial | — |