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etoposide

Generic: ETOPOSIDE·Brand: AVOPEF, Avopef, ETOPOPHOS PRESERVATIVE FREE, ETOPOSIDE, Etopophos, TOPOSAR, Toposar, VEPESID

etoposide: 109 clinical trials tracked.

etoposide evidence translation

What we can confirm

109 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about etoposide, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 10 study sponsors
Clinical Trial Registry Records (109)showing 10 most recent

A Phase 1b Trial of Adaptive Stereotactic Body Radiotherapy in Combination With Durvalumab (MEDI4736), Platinum, and Etoposide in Extensive Stage Small Cell Lung Cancer

NCT05403723Registry updated 2026-09-14·Phase 1
Suspended

Primary endpoint: Incidence of treatment-related adverse events (AEs)

Interventionalopen50 targetStarted 2027-01Completion 2028-081 site · United StatesUniversity of Maryland, Baltimore

A Phase Ib/II, Open-label, Safety and Tolerability Trial of Intravenous Obrixtamig in Combination With Pumitamig and Standard of Care (Carboplatin, Etoposide) in Patients With Extensive-stage Small Cell Lung Carcinoma

NCT07843940Registry updated 2026-09-30·Phase 1/Phase 2
Not yet recruiting

Primary endpoint: Occurrence of treatment-emergent adverse events (AEs) leading to trial medication discontinuation or dose modification

Interventionalopen55 targetStarted 2026-10Completion 2030-0427 sites · Australia, Belgium, China, France…Boehringer Ingelheim

A Randomized, Double-blind, Placebo-controlled, Phase III Trial of LBL-024 Combined With Platinum-based Chemotherapy as First-line Treatment of Patients With Advanced Extrapulmonary Neuroendocrine Carcinoma (EP-NEC)

NCT07720193Registry updated 2026-07-24·Phase 3
Not yet recruiting

Primary endpoint: Overall survival (OS)

InterventionalRandomizedtriple280 targetStarted 2026-08Completion 2030-1217 sites · ChinaNanjing Leads Biolabs Co.,Ltd

A Phase II Open Label Basket Trial Study Using Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

NCT07321912Registry updated 2026-06-12·Phase 2
Recruiting

Primary endpoint: Number of Cohort 1 participants with relapse free survival (RFS) during study

Interventionalopen406 targetStarted 2026-06Completion 2036-062 sites · United StatesMilton S. Hershey Medical Center

Dose-Adjusted Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) ± Rituximab + Recombinant Erwinia Asparaginase (JZP458; Rylaze®) for the Treatment of Newly-Diagnosed Adults With Philadelphia Chromosome-Negative Acute Lymphoblastic Lymphoma/Leukemia

NCT06738368Registry updated 2026-09-29·Phase 2
Suspended

Primary endpoint: Measurable residual disease (MRD) negativity

Interventionalopen30 targetStarted 2026-05Completion 2028-071 site · United StatesUniversity of Washington

Phase II Study of Dose-Adjusted EPOCH ± Rituximab + Ponatinib for Adults With Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma

NCT07224100Registry updated 2026-02-20·Phase 2
Recruiting

Primary endpoint: Rate of complete molecular response

Interventionalopen33 targetStarted 2026-03Completion 2028-071 site · United StatesUniversity of Washington

PHASE 2 Study of Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors (GLOBOTRK)

NCT06528691Registry updated 2026-02-17·Phase 2
Recruiting

Primary endpoint: Overall response rate (ORR) (Cohort 1)

Interventionalopen52 targetStarted 2026-03Completion 2032-112 sites · Jordan, United StatesSt. Jude Children's Research Hospital

Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes

NCT07194044Registry updated 2026-09-25·Phase 1
Recruiting

Primary endpoint: Feasibility and Safety - Consolidation

Interventionalopen15 targetStarted 2026-02Completion 2030-1021 sites · United StatesH. Lee Moffitt Cancer Center and Research Institute

A Phase II, Multicenter, Open-Label Study to Evaluate the Safety and Efficacy of SKB500 Combinations in Patients With Small Cell Lung Cancer

NCT07296809Registry updated 2026-04-02·Phase 2
Recruiting

Primary endpoint: Incidence and severity of adverse events (AEs)

Interventionalopen80 targetStarted 2026-01Completion 2029-121 site · ChinaSichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

A Phase 1b/2 Open-label Study Evaluating Different MK-6070 and Ifinatamab Deruxtecan (MK-2400)-Based Regimens in First-line Extensive Stage Small Cell Lung Cancer

NCT07227597Registry updated 2026-08-21·Phase 1/Phase 2
Recruiting

Primary endpoint: Number of Participants Who Experience an Adverse Event (AE)

InterventionalRandomizedopen170 targetStarted 2026-01Completion 2030-1250 sites · Argentina, Chile, China, Germany…Merck Sharp & Dohme LLC