Acute Myeloid Leukemia

Oncology·MeSH: Leukemia, Myeloid, Acute

Prevalence

6.0 / 100K

Incidence

4.3 / 100K/yr

183 drugs in development·73 companies·123 clinical trials

Drug Pipeline by Phase

Approved(7)

Drug	Company
company's product candidate uproleselan	CRESCENT BIOPHARMA, INC. (CBIO)
daurismo	PFIZER INC (PFE)
komzifti	Kura Oncology, Inc. (KURA)
nypozi	GT Biopharma, Inc. (GTBP)
Revuforj	Syndax Pharmaceuticals Inc (SNDX)
rezlidhia	RIGEL PHARMACEUTICALS INC (RIGL)
venetoclax	DR REDDYS LABORATORIES LTD (RDY)

Phase 3(50)

Drug	Company
BGB-11417	BeOne Medicines Ltd. (ONC)
cellcept	Filana Therapeutics Inc. (FLNA)
cellcept	ENANTA PHARMACEUTICALS INC (ENTA)
cellcept	Structure Therapeutics Inc. (GPCR)
ceplene	IMMUNE PHARMACEUTICALS INC (IMNP)
Cladribine	Jazz Pharmaceuticals plc (JAZZ)
clifutinib	SUNSHINE BIOPHARMA INC. (SBFM)
CPX-351	Jazz Pharmaceuticals plc (JAZZ)
Cytarabine	Jazz Pharmaceuticals plc (JAZZ)
Cytarabine	Merus N.V. (MRUS)
Cytarabine + Daunorubicin + Gilteritinib	Merus N.V. (MRUS)
Cytarabine + Daunorubicin + Gilteritinib	Crinetics Pharmaceuticals, Inc. (CRNX)
Daunorubicin	AbbVie Inc. (ABBV)
Daunorubicin	Jazz Pharmaceuticals plc (JAZZ)
Daunorubicin Hydrochloride	ENANTA PHARMACEUTICALS INC (ENTA)
Daunorubicin Hydrochloride	Merus N.V. (MRUS)
galinpepimut-s	SELLAS Life Sciences Group, Inc. (SLS)
gilteritinib	GH Research PLC (GHRS)
Gilteritinib Fumarate	Assertio Holdings, Inc. (ASRT)
gm-csf	SELLAS Life Sciences Group, Inc. (SLS)
HiDAC	Merus N.V. (MRUS)
High intensity therapies	Structure Therapeutics Inc. (GPCR)
hmpl-306 regimen	HUTCHMED (China) Ltd (HMDCF)
idarubicin	GH Research PLC (GHRS)
Idarubicin	AbbVie Inc. (ABBV)
Intensive Chemotherapy Regimen	Syndax Pharmaceuticals Inc (SNDX)
intrathecal chemotherapy	GH Research PLC (GHRS)
JCAR017 + venetoclax	Merus N.V. (MRUS)
kite-439	Kite Pharma, Inc. (KITE)
kite-585	Kite Pharma, Inc. (KITE)
kite-718	Kite Pharma, Inc. (KITE)
kite-796	Kite Pharma, Inc. (KITE)
Liposome-encapsulated Daunorubicin-Cytarabine	Jazz Pharmaceuticals plc (JAZZ)
Liposome-encapsulated Daunorubicin-Cytarabine	Merus N.V. (MRUS)
Low intensity therapies	Crinetics Pharmaceuticals, Inc. (CRNX)
Low intensity therapies	Structure Therapeutics Inc. (GPCR)
pevonedistat	TAKEDA PHARMACEUTICAL CO LTD (TKPHF)
pevonedistat	Takeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock) (TAK)
ponatinib	Incyte Corp. (INCY)
Revumenib	UNITED THERAPEUTICS Corp (UTHR)
salvage chemotherapy regimen	HUTCHMED (China) Limited (HCM)
salvage chemotherapy regimen	HUTCHMED (China) Ltd (HMDCF)
Tacrolimus	Structure Therapeutics Inc. (GPCR)
Tacrolimus	Filana Therapeutics Inc. (FLNA)
Venetoclax	Crinetics Pharmaceuticals, Inc. (CRNX)
Venetoclax	ENANTA PHARMACEUTICALS INC (ENTA)
Venetoclax	UNITED THERAPEUTICS Corp (UTHR)
Venetoclax	Merus N.V. (MRUS)
Venetoclax 400	UNITED THERAPEUTICS Corp (UTHR)
Vyxeos	Jazz Pharmaceuticals plc (JAZZ)

Phase 2(50)

Drug	Company
ABBV-787	AbbVie Inc. (ABBV)
acr-6840	Acrivon Therapeutics, Inc. (ACRV)
ALT-803	ImmunityBio, Inc. (IBRX)
BP1001	BIO-PATH HOLDINGS, INC. (BPTH)
Busulfan	Valneva SE (VALN)
Busulfan	Merus N.V. (MRUS)
Cytarabine	ENANTA PHARMACEUTICALS INC (ENTA)
Cytarabine	AbbVie Inc. (ABBV)
daunorubicin	Merus N.V. (MRUS)
Daunorubicin	ENANTA PHARMACEUTICALS INC (ENTA)
daunorubicin or idarubicin	NOVARTIS AG (NVSEF)
daunorubicin or idarubicin	Novartis AG (NVS)
Enasidenib	Merus N.V. (MRUS)
Filgrastim	Merus N.V. (MRUS)
fludarabine	Novartis AG (NVS)
fludarabine	NOVARTIS AG (NVSEF)
Fludarabine	Valneva SE (VALN)
Fludarabine	Merus N.V. (MRUS)
Fludarabine Phosphate	Merus N.V. (MRUS)
G-CSF	ImmunityBio, Inc. (IBRX)
gemtuzumab ozogamicin	GH Research PLC (GHRS)
Gemtuzumab Ozogamicin	ENANTA PHARMACEUTICALS INC (ENTA)
Gemtuzumab Ozogamicin	Merus N.V. (MRUS)
Gilteritinib	Merus N.V. (MRUS)
Inotuzumab ozogamicin	Merus N.V. (MRUS)
Lymphodepletion Conditioning	Filana Therapeutics Inc. (FLNA)
Melphalan	Valneva SE (VALN)
Melphalan	Merus N.V. (MRUS)
mitoxantrone	Novartis AG (NVS)
mitoxantrone	NOVARTIS AG (NVSEF)
mitoxantrone	GH Research PLC (GHRS)
Mitoxantrone	Jazz Pharmaceuticals plc (JAZZ)
mt-401	Marker Therapeutics, Inc. (MRKR)
mt-401-ots	Marker Therapeutics, Inc. (MRKR)
Mycophenolate mofetil	ImmunityBio, Inc. (IBRX)
nexi-001	NexImmune, Inc. (NEXI)
Olutasidenib	Merus N.V. (MRUS)
oxi4503	Oncotelic Therapeutics, Inc. (OTLC)
Pegfilgrastim	Merus N.V. (MRUS)
pivekimab sunirine	ImmunoGen, Inc. (IMGN)
Recombinant Granulocyte Colony-Stimulating Factor	Jazz Pharmaceuticals plc (JAZZ)
revumenib	GH Research PLC (GHRS)
rtx-240	Rubius Therapeutics, Inc. (RUBY)
Tacrolimus	ImmunityBio, Inc. (IBRX)
tagraxofusp	STEMLINE THERAPEUTICS INC (STML)
tamibarotene	Syros Pharmaceuticals, Inc. (SYRS)
tcb008	TC BioPharm (Holdings) plc (TCBWF)
UCART123v1.2	Cellectis S.A. (CLLS)
Venetoclax	Valneva SE (VALN)
Vincristine Sulfate Liposome	Merus N.V. (MRUS)

Phase 1(53)

Drug	Company
ACLX-002	Arcellx, Inc. (ACLX)
ADCLEC.syn1 CAR T cells	Filana Therapeutics Inc. (FLNA)
ADCLEC.syn1 CAR T cells	Merus N.V. (MRUS)
Alvocidib	AbbVie Inc. (ABBV)
AMG 176	AbbVie Inc. (ABBV)
astx727	CG Oncology, Inc. (CGON)
ASTX727	Syndax Pharmaceuticals Inc (SNDX)
BMF-500	Biomea Fusion, Inc. (BMEA)
CB-012	Caribou Biosciences, Inc. (CRBU)
cb-5339	CASI Pharmaceuticals, Inc (DE) (CASI)
CD371-specific/YSNVz/I-18 CAR T cells	Merus N.V. (MRUS)
Chemotherapy Regimen	Syndax Pharmaceuticals Inc (SNDX)
CLN-049	Cullinan Therapeutics, Inc. (CGEM)
Conditioning chemotherapy	Filana Therapeutics Inc. (FLNA)
Cytarabine	Structure Therapeutics Inc. (GPCR)
Cytarabine	Accustem Sciences Inc. (ACUT)
Cytarabine	Syndax Pharmaceuticals Inc (SNDX)
Etoposide Phosphate	Accustem Sciences Inc. (ACUT)
Fludarabine	AbbVie Inc. (ABBV)
Gemtuzumab Ozogamicin	Jazz Pharmaceuticals plc (JAZZ)
Gilteritinib	AbbVie Inc. (ABBV)
Gilteritinib	Jazz Pharmaceuticals plc (JAZZ)
Granulocyte Colony-Stimulating Factor	AbbVie Inc. (ABBV)
HiDAC	Syndax Pharmaceuticals Inc (SNDX)
Iadademstat	Merus N.V. (MRUS)
Idarubicin	Structure Therapeutics Inc. (GPCR)
Imetelstat	Assertio Holdings, Inc. (ASRT)
KT-253	Kymera Therapeutics, Inc. (KYMR)
Luveltamab tazevibulin	SUTRO BIOPHARMA, INC. (STRO)
Mitoxantrone Hydrochloride	Accustem Sciences Inc. (ACUT)
Navtemadlin	Merus N.V. (MRUS)
nc525	NextCure, Inc. (NXTC)
Pitavastatin	UNITED THERAPEUTICS Corp (UTHR)
Pivekimab Sunirine	Structure Therapeutics Inc. (GPCR)
Pivekimab Sunirine	AbbVie Inc. (ABBV)
quizartinib	Kura Oncology, Inc. (KURA)
Revumenib	AbbVie Inc. (ABBV)
Revumenib	Syndax Pharmaceuticals Inc (SNDX)
Revumenib	Merus N.V. (MRUS)
sgr-2921	Schrodinger, Inc. (SDGR)
siremadlin	Novartis AG (NVS)
sl-172154	Shattuck Labs, Inc. (STTK)
SNDX-5613	Syndax Pharmaceuticals Inc (SNDX)
SNDX-5613	Merus N.V. (MRUS)
Tazemetostat	Merus N.V. (MRUS)
Venetoclax	Actinium Pharmaceuticals, Inc. (ATNM)
Venetoclax	Syndax Pharmaceuticals Inc (SNDX)
voruciclib	Lite Strategy, Inc. (LITS)
vyxeos	GH Research PLC (GHRS)
Vyxeos liposomal	Jazz Pharmaceuticals plc (JAZZ)
ze 50-0134	Rani Therapeutics Holdings, Inc. (RANI)
ze50-0134	Rani Therapeutics Holdings, Inc. (RANI)
ZN-d5	Zentalis Pharmaceuticals, Inc. (ZNTL)

Preclinical(11)

Drug	Company
ACLX-004	Arcellx, Inc. (ACLX)
cd38-gear-nk	COEPTIS THERAPEUTICS INC. (NDYN)
CD38-GEAR-NK	Coeptis Therapeutics Holdings Inc. (COEP)
gb3226	Damora Therapeutics, Inc. (DMRA)
oncotox-aml	OMEROS CORP (OMER)
prime edited scip	Prime Medicine, Inc. (PRME)
rasp-101	ACTAVIA LIFE SCIENCES, INC. (RASP)
rasp-201	ACTAVIA LIFE SCIENCES, INC. (RASP)
rasp-301	ACTAVIA LIFE SCIENCES, INC. (RASP)
tp-2846	TETRAPHASE PHARMACEUTICALS INC (TTPH)
tp-2846	LA JOLLA PHARMACEUTICAL CO (LJPC)

Unknown(1)

Drug	Company
BST-236	Ayala Pharmaceuticals, Inc. (ADXS)

Clinical(1)

Drug	Company
ast-vac1	ASTERIAS BIOTHERAPEUTICS, INC. (AST)

Phase 1/Phase 2(6)

Drug	Company
cobicistat	Syndax Pharmaceuticals Inc (SNDX)
debio 1562m	HWH International Inc. (HWH)
ft-2102	Forma Therapeutics Holdings, Inc. (FMTX)
nkx101	Nkarta, Inc. (NKTX)
Posaconazole	BeOne Medicines Ltd. (ONC)
sar443579	Sanofi (SNY)

Phase 2/Phase 3(1)

Drug	Company
Actimab-A	Actinium Pharmaceuticals, Inc. (ATNM)

Phase 4(3)

Drug	Company
bms-986497	BRISTOL MYERS SQUIBB CO (BMY)
cyp1a2	RIGEL PHARMACEUTICALS INC (RIGL)
Venetoclax	AbbVie Inc. (ABBV)

Compare drugs

company's product candidate uproleselan vs daurismo company's product candidate uproleselan vs komzifti company's product candidate uproleselan vs nypozi

Frequently asked questions

How many drugs are in development for Acute Myeloid Leukemia?

BioSniper tracks 183 drugs in development for Acute Myeloid Leukemia across 73 companies.

How many clinical trials target Acute Myeloid Leukemia?

There are 123 clinical trials targeting Acute Myeloid Leukemia tracked by BioSniper.

What is the prevalence of Acute Myeloid Leukemia?

The estimated prevalence of Acute Myeloid Leukemia is approximately 6.0 per 100,000 population.

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