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tislelizumab

Generic: tislelizumab·Brand: Tevimbra

tislelizumab: 60 clinical trials tracked.

tislelizumab evidence translation

What we can confirm

60 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about tislelizumab, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 11 study sponsors
Clinical Trials (60)showing 10 most recent

Addition of Platinum-based Chemotherapy to Tislelizumab in PD-L1high Metastatic Non-small Cell Lung Cancer With a High Tumor Burden

NCT07715396·Phase 3
Not yet recruiting

Primary endpoint: Progression-free survival

InterventionalRandomizedopen230 targetStarted 2026-10Completion 2031-101 site · GermanyAIO-Studien-gGmbH

A Phase 1a/1b Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of BG-85738, Alone or in Combination With Other Antitumor Agents, in Patients With Advanced or Metastatic Solid Tumors With RAS Mutations

NCT07746141·Phase 1·ONC
Not yet recruiting

Primary endpoint: Phase 1a (Part A and Part B): Number of Participants with Adverse Events (AEs) and Serious Adverse Events (SAEs)

Interventionalopen100 targetStarted 2026-09Completion 2028-09BeOne Medicines

A Phase 2 Study of Tislelizumab Administered With Alternative Dosing Schedules Plus Chemotherapy as First-line Treatment in Japanese Patients With Unresectable Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma

NCT07733180·Phase 2·ONC
Not yet recruiting

Primary endpoint: Serum Concentrations of Tislelizumab at Specified Time Points

InterventionalRandomizedopen30 targetStarted 2026-08Completion 2028-02BeOne Medicines

A Prospective, Single-arm, Multicenter Phase II Clinical Study to Evaluate the Efficacy and Safety of Spatially Fractionated Radiotherapy Combined With Tislelizumab and Platinum-based Doublet Chemotherapy as Induction/Conversion Therapy for Potentially Resectable Stage III Non-small Cell Lung Cancer With Bulky Disease.

NCT07775040·Phase 2·GHRS
Not yet recruiting

Primary endpoint: Major Pathological Response (MPR) Rate

Interventionalopen43 targetStarted 2026-08Completion 2030-061 site · ChinaSichuan Cancer Hospital and Research Institute

A Phase II, Multicenter, Open-Label Study to Evaluate the Safety and Efficacy of SKB500 Combinations in Patients With Esophageal Squamous Cell Carcinoma

NCT07700667·Phase 2
Recruiting

Primary endpoint: Objective Response Rate (ORR)

InterventionalRandomizedopen120 targetStarted 2026-08Completion 2029-1224 sites · ChinaSichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

AACR Adaptive Biomarker-Driven Organ Preservation Trial In Gastroesophageal Adenocarcinomas (AACR-ADOPT-GEA)

NCT07290985·Phase 2
Recruiting

Primary endpoint: Pathological Complete Response (pathCR) Rate (Stage I).

Interventionalopen242 targetStarted 2026-07Completion 2028-123 sites · Canada, United StatesAmerican Association for Cancer Research

A Phase II Study Evaluating the Efficacy and Safety of SKB315 Combination Therapy in Claudin18.2 Positive Patients With Unresectable Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

NCT07609667·Phase 2
Not yet recruiting

Primary endpoint: Objective Response Rate (ORR)

InterventionalRandomizedopen80 targetStarted 2026-06Completion 2029-061 site · ChinaSichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

A Pilot Study of Neoadjuvant mFOLFIRINOX and ELI002-7P Treatment With or Without Tislelizumab in Borderline and Resectable Pancreatic Ductal Adenocarcinoma

NCT07671339·Phase 1
Recruiting

Primary endpoint: the proportion of patients with a Grade 3 or higher drug-related adverse event (AE)

InterventionalRandomizedopen20 targetStarted 2026-06Completion 2028-067 sites · United StatesMemorial Sloan Kettering Cancer Center

KontRASt-R: An Open-label, Multi-center, Rollover Study for Participants Who Have Been Previously Enrolled Into a Novartis-sponsored Opnurasib (JDQ443) Study and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments

NCT07468071·Phase 1/Phase 2·NVS
Recruiting

Primary endpoint: Number of participants receiving opnurasib as single agent or in combination with other study treatments

Interventionalopen40 targetStarted 2026-06Completion 2029-0915 sites · Belgium, Canada, China, Denmark…Novartis Pharmaceuticals

A Real-World Evaluation of Tislelizumab Treatment Patterns and Effectiveness in European Patients With Resectable or Advanced Non-Small Cell Lung Cancer and Small Cell Lung Cancer

Recruiting

Primary endpoint: Time from Diagnosis to First Dose

Observational440 targetStarted 2026-06Completion 2030-111 site · SpainBeOne Medicines