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fluorouracil

Generic: FLUOROURACIL·Brand: ADRUCIL, Adrucil, CARAC, Carac, EFUDEX, Efudex, FAVLYXA, FLUOROPLEX, FLUOROURACIL, Favlyxa, Fluoroplex, TOLAK, Tolak

fluorouracil: 86 clinical trials tracked.

fluorouracil evidence translation

What we can confirm

86 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about fluorouracil, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 9 study sponsors
Clinical Trial Registry Records (86)showing 10 most recent

A Phase 1/2 Trial of Chemoradiotherapy With 5-Fluorouracil and Maintenance Chemotherapy for High-Risk Posterior Fossa Ependymoma

NCT07848568Registry updated 2026-09-30·Phase 1/Phase 2
Not yet recruiting

Primary endpoint: Occurrence of dose limiting toxicity chemoradiotherapy (DLT) (phase 1)

Interventionalopen70 targetStarted 2026-12Completion 2037-06Children's Oncology Group

A Randomized, Open-label, Phase 3 Trial of Petosemtamab + FOLFIRI/mFOLFOX6 Versus Cetuximab or Bevacizumab + FOLFIRI/mFOLFOX6 as Second-line Treatment in Participants With RAS and BRAF Wild-type, Recurrent, Unresectable or Metastatic Colorectal Cancer

NCT07775287Registry updated 2026-10-09·Phase 3
Recruiting

Primary endpoint: Progression-free Survival (PFS) per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 as Assessed by Blinded Independent Central Review (BICR)

InterventionalRandomizedopen600 targetStarted 2026-10Completion 2030-014 sites · Puerto Rico, United StatesGenmab

Investigation of Mitomycin C PIPAC - FOLFIRI Combination for Unresectable Appendiceal or Colorectal Peritoneal Metastases Treatment (IMPACT): A Multicenter, Randomized, Open-Label, Phase 3 Trial

NCT07271355Registry updated 2026-08-21·Phase 3
Not yet recruiting

Primary endpoint: Overall survival (OS)

InterventionalRandomizedopen129 targetStarted 2026-10Completion 2031-025 sites · United StatesCity of Hope Medical Center

A Phase 2 Open-Label Randomized Study to Evaluate the Safety, Efficacy, and Optimal Dose of Telisotuzumab Adizutecan in Combination With Pembrolizumab as First-Line Treatment in Subjects With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

NCT07744126Registry updated 2026-09-29·Phase 2·ABBV
Recruiting

Primary endpoint: Number of Participants with Adverse Events (AE)s

InterventionalRandomizedopen150 targetStarted 2026-09Completion 2029-103 sites · Taiwan, United StatesAbbVie

A Phase I Clinical Trial of Ivonescimab and ADG126, Alone, and in Combination With 5-FU/LV or FOLFIRI in MSS Advanced/Metastatic Colorectal Cancer

NCT07363408Registry updated 2026-01-23·Phase 1
Not yet recruiting

Primary endpoint: Incidence of dose limiting toxicities

Interventionalopen30 targetStarted 2026-07Completion 2027-071 site · United StatesCity of Hope Medical Center

AACR Adaptive Biomarker-Driven Organ Preservation Trial In Gastroesophageal Adenocarcinomas (AACR-ADOPT-GEA)

NCT07290985Registry updated 2026-10-05·Phase 2
Recruiting

Primary endpoint: Pathological Complete Response (pathCR) Rate (Stage I).

Interventionalopen242 targetStarted 2026-07Completion 2028-124 sites · Canada, United StatesAmerican Association for Cancer Research

Randomized Phase III Study of Second-Line Chemotherapy With or Without Panitumumab for KRAS Wild Type, Locally Advanced or Metastatic Pancreatic Adenocarcinoma

NCT06998940Registry updated 2026-05-22·Phase 3
Recruiting

Primary endpoint: Overall survival (OS)

InterventionalRandomizedopen94 targetStarted 2026-05Completion 2030-1250 sites · United StatesSWOG Cancer Research Network

A PHASE 3, OPEN-LABEL, RANDOMIZED STUDY TO EVALUATE ENFORTUMAB VEDOTIN IN COMBINATION WITH PEMBROLIZUMAB IN ADULT PARTICIPANTS WITH MUSCLE-INVASIVE BLADDER CANCER WHO ARE INELIGIBLE FOR OR HAVE ELECTED NOT TO UNDERGO CYSTECTOMY

NCT07566156Registry updated 2026-09-30·Phase 3
Recruiting

Primary endpoint: Bladder-intact Event Free Survival (BI-EFS) by Blinded Independent Central Review (BICR)

InterventionalRandomizedopen390 targetStarted 2026-05Completion 2032-0219 sites · Canada, South Korea, Taiwan, United StatesAstellas Pharma Global Development, Inc.

Solid Tumor Study for Long Term Treatment of Cancer Patients Who Have Participated in BMS Parent Studies Investigating Adagrasib (BMS-986503)

NCT07415031Registry updated 2026-05-15·Phase 2·MRTX
Recruiting

Primary endpoint: Number of Participants With Adverse Events (AEs)

Interventionalopen170 targetStarted 2026-05Completion 2028-0250 sites · Australia, Belgium, Canada, France…Mirati Therapeutics Inc.

Phase 2/3 Open Label Randomized Study of Telisotuzumab Adizutecan in Combination With FOLFOX Compared to Standard of Care in Subjects With First-Line Metastatic Pancreatic Ductal Adenocarcinoma - AndroMETa-PDAC-288

NCT07490301Registry updated 2026-10-05·Phase 2/Phase 3·ABBV
Recruiting

Primary endpoint: Phase 2 and Phase 3: Overall Response (OR) Assessed by Blinded Independent Central Review (BICR) per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1

InterventionalRandomizedopen900 targetStarted 2026-04Completion 2031-0620 sites · Australia, Israel, Japan, South Korea…AbbVie