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tocilizumab

Generic: tocilizumab·Brand: Actemra, Avtozma, Tofidence, Tyenne

tocilizumab: 31 clinical trials tracked.

tocilizumab evidence translation

What we can confirm

31 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about tocilizumab, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 11 study sponsors
Clinical Trials (31)showing 10 most recent

A Phase 2, Open-label, Multicenter Study to Determine the Safety, Tolerability, and Efficacy of MK-1045 in Participants With Hematologic Malignancies

NCT07709000·Phase 2
Not yet recruiting

Primary endpoint: Cohort A Part 1: Number of Participants Who Experience Dose-Limiting Toxicity (DLT)

Interventionalsingle60 targetStarted 2026-09Completion 2033-113 sites · IsraelMerck Sharp & Dohme LLC

Application of the Personalized N-of-1 Trial Design in Patients With Rheumatoid Arthritis

Not yet recruiting

Primary endpoint: Change in Disease Activity Score (DAS) 28

Observational18 targetStarted 2026-09Completion 2028-121 site · United StatesTufts Medical Center

A Multicenter, Phase 1, Safety and Tolerability Study of CC-97540 (BMS- 986353) in Anti-Aquaporin 4 Antibody Positive Neuromyelitis Optica Patients

NCT07573332·Phase 1
Not yet recruiting

Primary endpoint: To evaluate the safety and tolerability of CC-97540 (BMS-986353) in participants with anti-AQP4 antibody positive NMO as determined by the proportion of patients experiencing DLTs

Interventionalopen5 targetStarted 2026-09Completion 2031-081 site · United StatesUniversity of Texas Southwestern Medical Center

A Phase 3, Randomized, Open-label, Multicenter Study to Compare the Efficacy and Safety of BMS-986353, CD19-targeted NEX-T CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis (Breakfree-SSc)

NCT07335562·Phase 3·BMY
Not yet recruiting

Primary endpoint: The absolute change from baseline in Forced Vital Capacity (FVC) in mL

InterventionalRandomizedopen92 targetStarted 2026-08Completion 2030-1150 sites · Belgium, Canada, France, Germany…Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

A Phase II, Nonrandomized, Single-Arm Study of Elranatamab Outpatient Administration in Patients With Relapsed/Refractory Multiple Myeloma (CORE-MM)

NCT07637578·Phase 2
Recruiting

Primary endpoint: Incidence of Cytokine Release Syndrome (CRS) in Cycle 1

Interventionalopen46 targetStarted 2026-08Completion 2030-025 sites · United StatesSCRI Development Innovations, LLC

A Phase 4, Single-Arm, Multicenter Study of Prophylactic Tocilizumab in Participants With Relapsed/Refractory Multiple Myeloma Treated With Linvoseltamab in the Outpatient Setting

NCT07609940·Phase 4·REGN
Recruiting

Primary endpoint: Occurrence of any grade CRS per American Society for Transplantation and Cellular Therapy (ASTCT) grading

Interventionalopen30 targetStarted 2026-07Completion 2028-123 sites · United StatesRegeneron Pharmaceuticals

Treatment Strategy for Patients With Rheumatoid Arthritis Associated Interstitial Lung Disease

NCT07643038·Phase 4
Not yet recruiting

Primary endpoint: Change in FVC from baseline to week 52

InterventionalRandomizedopen204 targetStarted 2026-07Completion 2029-0722 sites · ChinaChinese SLE Treatment And Research Group

79635322MMY2002: Phase 2 Randomized, Double-blind, Placebo-controlled Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release Syndrome With Ramantamig Administration in Participants With Relapsed/Refractory Multiple Myeloma

NCT07589634·Phase 2·GHRS
Recruiting

Primary endpoint: Percentage of Participants Alive and Free of Treatment-Emergent American Society for Transplantation and Cellular Therapy (ASTCT) Grade Greater Than or Equal to (>=) 2 Cytokine Release Syndrome (CRS)

InterventionalRandomizeddouble230 targetStarted 2026-06Completion 2030-124 sites · Malaysia, United StatesJanssen Research & Development, LLC

A Phase 2/3, Randomized, Open-Label, Comparison Study of MK-1045 Versus Blinatumomab in Participants With Relapsed or Refractory CD19+ B-Cell Acute Lymphoblastic Leukemia (B-ALL)

NCT07570173·Phase 2/Phase 3
Recruiting

Primary endpoint: Percentage of Participants with Complete Remission (CR) in Study Part 1 and Part 2

InterventionalRandomizedsingle340 targetStarted 2026-05Completion 2033-1019 sites · Denmark, Greece, Israel, Italy…Merck Sharp & Dohme LLC

Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis

NCT06654882·Phase 3·CDTX
Recruiting

Primary endpoint: Number of participants with MiDA

InterventionalRandomizedopen400 targetStarted 2026-01Completion 2026-124 sites · United StatesDuke University