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ipatasertib

·Code: GDC-0068

ipatasertib: sourced relationships with 1 company · 8 clinical trials tracked.

ipatasertib evidence translation

What we can confirm

What it means

Source-backed records connect ipatasertib to ARRY; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could ipatasertib → ARRY affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 0 study sponsors

Study sponsors

No additional listed-company sponsor is linked.

Dated Pipeline Records (1)
CompanyDated record stage
ARRAY BIOPHARMA INC (ARRY)
developer · Reported 2018-08-14 · Current development: unknownSource
Phase 3
Clinical Trial Registry Records (8)

Phase 2 Study of Paclitaxel (NSC #673089) + Ipatasertib (NSC #781451) in Taxane-Refractory Participants With PTEN/AKT-Altered Advanced Non-Breast Solid Tumors: A ComboMATCH Treatment Trial

NCT05554380Registry updated 2026-02-19·Phase 2
Suspended

Primary endpoint: Objective response rate (ORR)

Interventionalopen33 targetStarted 2023-09Completion 2026-0850 sites · United StatesNational Cancer Institute (NCI)

An Open-Label, Multicenter Extension Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Study

NCT05862285Registry updated 2026-02-13·Phase 3
Recruiting

Primary endpoint: Number of Participants With Continued Access to Roche IMP(s)-Based Therapy and/or Comparator Agent(s)

Interventionalopen100 targetStarted 2023-06Completion 2033-0350 sites · Belgium, Canada, China, Costa Rica…Hoffmann-La Roche

Molecular Analysis for Combination Therapy Choice (ComboMATCH)

NCT05564377Registry updated 2026-02-20·Phase 2
Recruiting

Primary endpoint: Accrual of patients to ComboMATCH treatment trials

InterventionalRandomizedopen2,900 targetStarted 2023-04Completion 2030-0750 sites · United StatesNational Cancer Institute (NCI)

A Phase IB/II Multi-Cohort Study of Targeted Agents and/or Immunotherapy With Atezolizumab for Patients With Recurrent or Persistent Endometrial Cancer

NCT04486352Registry updated 2026-04-01·Phase 1/Phase 2
Recruiting

Primary endpoint: Investigator-assessed overall response rate (ORR) of each biomarker cohort

Interventionalopen148 targetStarted 2021-10Completion 2027-1021 sites · United StatesAlliance Foundation Trials, LLC.

A Phase Ib/II, Open-Label, Multicenter, Randomized Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Breast Cancer (MORPHEUS-BREAST CANCER)

NCT04802759Registry updated 2026-02-13·Phase 1
Recruiting

Primary endpoint: Percentage of Participants with Objective Response, Defined as a Complete or Partial Response, as Determined by the Investigator According to Response Evaluation Criteria in Solid Tumors, version 1.1 (RECIST v1.1)

InterventionalRandomizedopen316 targetStarted 2021-06Completion 2029-0531 sites · Australia, Israel, South Korea, Spain…Hoffmann-La Roche

Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Phase II Platform Trial

NCT04589845Registry updated 2026-02-09·Phase 2
Recruiting

Primary endpoint: All Cohorts: Independent Review Committee (IRC)-assessed Objective Response Rate (ORR) Based on Confirmed Objective Response (OR) per Response Evaluation Criteria in Solid Tumors, Version 1.1 (RECIST v1.1)

Interventionalopen920 targetStarted 2021-01Completion 2032-0950 sites · United StatesHoffmann-La Roche

A Phase Ib/II, Open-label, Multicenter, Randomized Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic Breast Cancer (Morpheus-panBC)

NCT03424005Registry updated 2026-09-10·Phase 1/Phase 2
Recruiting

Primary endpoint: Objective Response Rate (ORR)

InterventionalRandomizedopen1,132 targetStarted 2018-03Completion 2030-0950 sites · Australia, France, Germany, Israel…Hoffmann-La Roche

Molecular Analysis for Therapy Choice (MATCH)

NCT02465060Registry updated 2026-02-27·Phase 2
Active, not recruiting

Primary endpoint: Objective response rate (ORR)

Interventionalopen6,452 targetStarted 2015-08Completion 2026-1250 sites · United StatesNational Cancer Institute (NCI)

Frequently asked questions

Which companies have sourced relationships with ipatasertib?

ipatasertib has dated SEC/FDA relationship records for ARRAY BIOPHARMA INC.

How many clinical trials involve ipatasertib?

BioSniper tracks 8 clinical trials involving ipatasertib.