afatinib
afatinib: 7 clinical trials tracked.
afatinib evidence translation
What we can confirm
7 tracked trials
What it means
What to watch
Prepared research question
What is verified about afatinib, and what remains unknown?
Traceable citations · Unknowns marked
See linked entities and source evidence8 indications · 1 study sponsors
Clinical Trial Registry Records (7)
A Prospective Randomized Controlled Trial Comparing Low-Dose Radiotherapy Combined With Targeted Therapy and Immunotherapy Versus Targeted Therapy and Immunotherapy Alone as Neoadjuvant Therapy in Patients With Operable Head and Neck Squamous Cell Carcinoma.
Primary endpoint: Major Pathologic Response
Neoadjuvant Low-Dose Radiotherapy Plus Targeted Therapy and Immunotherapy vs. Targeted Therapy Plus Immunotherapy in Resectable Head and Neck Squamous Cell Carcinoma: A Prospective Randomized Controlled Trial
Primary endpoint: Major Pathologic Response
A Phase Ia/Ib Study of the Combination of the FGFR Inhibitor Pemigatinib and the EGFR Inhibitor Afatinib in Advanced Refractory Solid Tumors
Primary endpoint: Maximum tolerated dose (MTD)
Phase 2 Study of Afatinib in Advanced Cutaneous Squamous Cell Carcinoma
Primary endpoint: Overall Response Rate
A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients With Advanced Solid Tumors With KRAS G12C Mutation KRYSTAL-1
Primary endpoint: Characterize the safety of MRTX849 in patients having advanced solid tumor malignancies with KRAS G12C mutation
A Dutch National Study on Behalf of the CPCT to Facilitate Patient Access to Commercially Available, Targeted Anti-cancer Drugs to Determine the Potential Efficacy in Treatment of Advanced Cancers With a Known Molecular Profile
Primary endpoint: Percentage of patients that are treated based on their molecular tumor profile
Molecular Analysis for Therapy Choice (MATCH)
Primary endpoint: Objective response rate (ORR)