| GILDGILEAD SCIENCES, INC. | 56,605 | $7.9M |
| SNYSanofi | 56,900 | $2.7M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 32,829 | $1.8M |
| REGNREGENERON PHARMACEUTICALS, INC. | 1,870 | $1.5M |
| MRNAModerna, Inc. | 20,211 | $1.0M |
| SMMTSummit Therapeutics Inc. | 50,316 | $952K |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 11,971 | $753K |
| EXELEXELIXIS, INC. | 16,443 | $724K |
| BMRNBIOMARIN PHARMACEUTICAL INC | 7,857 | $450K |
| VKTXViking Therapeutics, Inc. | 13,587 | $448K |
| INSMINSMED Inc | 2,162 | $356K |
| TEVATeva Pharmaceutical Industries Limited | 11,152 | $337K |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 910 | $299K |
| PLSEPulse Biosciences Inc Common Stock (DE) | 12,160 | $280K |
| ARGXARGENX SE | 333 | $247K |
| INVAInnoviva, Inc. | 8,713 | $204K |
| RDYDR REDDYS LABORATORIES LTD | 13,515 | $182K |
| INCYIncyte Corp. | 1,820 | $172K |
| SVRASavara Inc | 26,903 | $150K |
| LGNDLigand Pharmaceuticals Incorporated | 718 | $143K |
| IONSIONIS PHARMACEUTICALS INC | 1,883 | $141K |
| ALMSALUMIS INC. | 6,010 | $137K |
| ORGOOrganogenesis Holdings Inc. | 57,415 | $133K |
| IBRXImmunityBio, Inc. | 15,540 | $111K |
| BBIOBridgeBio Pharma, Inc. | 1,473 | $110K |
| JAZZJazz Pharmaceuticals plc | 573 | $108K |
| ADMAADMA BIOLOGICS, INC. | 11,832 | $108K |
| NUVLNuvalent, Inc. | 1,009 | $107K |
| RVMDREVOLUTION MEDICINES, INC. | 968 | $95K |
| KNSAKiniksa Pharmaceuticals International, plc | 1,536 | $74K |
| CYTKCYTOKINETICS INC | 1,109 | $74K |
| ONCBeOne Medicines Ltd. | 222 | $68K |
| IMVTImmunovant, Inc. | 2,486 | $62K |
| ABCLAbCellera Biologics Inc. | 16,645 | $58K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 645 | $57K |
| ROIVRoivant Sciences Ltd. | 1,950 | $54K |
| GMABGenmab A/S | 1,885 | $51K |
| AXSMAxsome Therapeutics, Inc. | 292 | $50K |
| GPCRStructure Therapeutics Inc. | 931 | $47K |
| RLAYRelay Therapeutics, Inc. | 4,301 | $46K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 11,508 | $40K |
| PTCTPTC THERAPEUTICS, INC. | 551 | $38K |
| CTMXCytomX Therapeutics, Inc. | 7,875 | $36K |
| PTGXProtagonist Therapeutics, Inc | 333 | $35K |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 1,018 | $33K |
| PCVXVaxcyte, Inc. | 558 | $33K |
| KODKodiak Sciences Inc. | 758 | $32K |
| ELVNEnliven Therapeutics, Inc. | 810 | $31K |
| GLSIGreenwich LifeSciences, Inc. | 1,319 | $30K |
| FOLDAMICUS THERAPEUTICS, INC. | 1,930 | $28K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 8,963 | $27K |
| PRTAPROTHENA CORP PUBLIC LTD CO | 2,734 | $27K |
| DMACDiaMedica Therapeutics Inc. | 4,235 | $27K |
| VRDNViridian Therapeutics, Inc.\DE | 1,229 | $24K |
| ANABANAPTYSBIO, INC | 384 | $22K |
| VCELVericel Corp | 595 | $19K |
| OGNOrganon & Co. | 3,139 | $19K |
| ABVXAbivax SA | 161 | $19K |
| DAREDare Bioscience, Inc. | 9,325 | $18K |
| TGTXTG THERAPEUTICS, INC. | 525 | $18K |
| NTLAIntellia Therapeutics, Inc. | 1,234 | $16K |
| GRFSGrifols S.A. | 1,984 | $16K |
| LQDALiquidia Corp | 410 | $15K |
| XERSXeris Biopharma Holdings, Inc. | 2,469 | $15K |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 283 | $15K |
| LRMRLarimar Therapeutics, Inc. | 3,106 | $15K |
| BHVNBiohaven Ltd. | 1,493 | $14K |
| KALVKalVista Pharmaceuticals, Inc. | 631 | $12K |
| MLTXMoonLake Immunotherapeutics | 733 | $12K |
| DFTXDefinium Therapeutics Inc. | 567 | $12K |
| SRRKScholar Rock Holding Corp | 233 | $11K |
| ACADACADIA PHARMACEUTICALS INC | 492 | $11K |
| RCKTRocket Pharmaceuticals Inc. | 3,025 | $11K |
| IRDOpus Genetics, Inc. | 2,300 | $11K |
| TVTXTravere Therapeutics, Inc. | 337 | $11K |
| OCULOCULAR THERAPEUTIX, INC | 1,252 | $10K |
| MAZEMaze Therapeutics, Inc. | 359 | $10K |
| CMPSCOMPASS Pathways plc | 1,828 | $10K |
| CLDXCelldex Therapeutics, Inc. | 324 | $10K |
| MESOMesoblast Limited | 640 | $10K |
| SLSSELLAS Life Sciences Group, Inc. | 2,360 | $10K |
| NUVBNuvation Bio Inc. | 2,183 | $10K |
| ARQTArcutis Biotherapeutics, Inc. | 352 | $8K |
| CGEMCullinan Therapeutics, Inc. | 605 | $8K |
| BEAMBeam Therapeutics Inc. | 347 | $8K |
| SIONSionna Therapeutics, Inc. | 196 | $8K |
| SIGASIGA TECHNOLOGIES INC | 1,535 | $8K |
| TNGXTango Therapeutics, Inc. | 372 | $8K |
| ELTXElicio Therapeutics, Inc. | 721 | $8K |
| ANIPANI PHARMACEUTICALS INC | 100 | $8K |
| SANASana Biotechnology, Inc. | 2,490 | $8K |
| ALDXAldeyra Therapeutics, Inc. | 4,450 | $7K |
| ANNXAnnexon, Inc. | 1,365 | $7K |
| AVXLANAVEX LIFE SCIENCES CORP. | 2,251 | $7K |
| GERNGERON CORP | 4,166 | $7K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 202 | $7K |
| RGCRegencell Bioscience Holdings Ltd | 201 | $7K |
| SLNOSOLENO THERAPEUTICS INC | 164 | $6K |
| NRIXNurix Therapeutics, Inc. | 359 | $6K |
| KURAKura Oncology, Inc. | 642 | $5K |
| DNLIDenali Therapeutics Inc. | 255 | $5K |
| RLMDRELMADA THERAPEUTICS, INC. | 684 | $5K |
| DAWNDay One Biopharmaceuticals, Inc. | 216 | $5K |
| QNTMQuantum Biopharma Ltd. | 1,000 | $4K |
| DSGNDesign Therapeutics, Inc. | 386 | $4K |
| COGTCogent Biosciences, Inc. | 114 | $4K |
| CNTXContext Therapeutics Inc. | 1,500 | $4K |
| APLSApellis Pharmaceuticals, Inc. | 95 | $4K |
| PBYIPUMA BIOTECHNOLOGY, INC. | 566 | $4K |
| CHRSCoherus Oncology, Inc. | 2,135 | $4K |
| FLGTFulgent Genetics Inc. | 225 | $4K |
| NGNENeurogene Inc. | 170 | $4K |
| SYRESpyre Therapeutics, Inc. | 74 | $4K |
| RCUSArcus Biosciences, Inc. | 163 | $4K |
| CMPXCompass Therapeutics, Inc. | 655 | $4K |
| IMTXImmatics N.V. | 335 | $3K |
| TERNTerns Pharmaceuticals, Inc. | 62 | $3K |
| IMCRImmunocore Holdings plc | 107 | $3K |
| RGNXREGENXBIO Inc. | 368 | $3K |
| LENZLENZ Therapeutics, Inc. | 337 | $3K |
| TECXTectonic Therapeutic, Inc. | 102 | $3K |
| OPKOPKO HEALTH, INC. | 2,729 | $3K |
| PGENPRECIGEN, INC. | 755 | $3K |
| SPRYARS Pharmaceuticals, Inc. | 365 | $3K |
| ABSIAbsci Corporation | 913 | $3K |
| DNTHDianthus Therapeutics, Inc. /DE/ | 34 | $3K |
| IRONDisc Medicine, Inc. | 44 | $3K |
| ABEOABEONA THERAPEUTICS INC. | 618 | $3K |
| OLMAOlema Pharmaceuticals, Inc. | 180 | $3K |
| APGEApogee Therapeutics, Inc. | 31 | $3K |
| MPLTMapLight Therapeutics, Inc. | 120 | $3K |
| BIOABioAge Labs, Inc. | 136 | $2K |
| ADPTAdaptive Biotechnologies Corp | 167 | $2K |
| DNAGinkgo Bioworks Holdings Inc. | 332 | $2K |
| ARVNARVINAS, INC. | 183 | $2K |
| ZVRAZEVRA THERAPEUTICS, INC. | 210 | $2K |
| RZLTRezolute, Inc. | 624 | $2K |
| QUREuniQure N.V. | 112 | $2K |
| TNXPTonix Pharmaceuticals Holding Corp. | 136 | $2K |
| MDWDMediWound Ltd. | 111 | $2K |
| FENCFENNEC PHARMACEUTICALS INC. | 280 | $2K |
| PRQRProQR Therapeutics N.V. | 1,000 | $2K |
| BCAXBicara Therapeutics Inc. | 80 | $2K |
| CYPHCYPHERPUNK TECHNOLOGIES INC. | 2,058 | $2K |
| ARDXARDELYX, INC. | 255 | $2K |
| CATXPerspective Therapeutics, Inc. | 348 | $2K |
| ZYMEZymeworks Inc. | 57 | $1K |
| GHRSGH Research PLC | 100 | $1K |
| XFORX4 Pharmaceuticals, Inc | 331 | $1K |
| STOKStoke Therapeutics, Inc. | 40 | $1K |
| AVTXAvalo Therapeutics, Inc. | 75 | $1K |
| JBIOJade Biosciences, Inc. | 78 | $1K |
| FDMT4D Molecular Therapeutics, Inc. | 125 | $1K |
| HURATuHURA Biosciences, Inc./NV | 688 | $1K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 36 | $1K |
| KROSKeros Therapeutics, Inc. | 86 | $1K |
| VYGRVoyager Therapeutics, Inc. | 228 | $910 |
| LCTXLineage Cell Therapeutics, Inc. | 544 | $865 |
| PTHSPelthos Therapeutics Inc. | 40 | $852 |
| CNTACentessa Pharmaceuticals plc | 20 | $797 |
| HROWHARROW, INC. | 22 | $779 |
| FATEFATE THERAPEUTICS INC | 620 | $769 |
| UPBUpstream Bio, Inc. | 81 | $754 |
| KRROKorro Bio, Inc. | 54 | $683 |
| ORKAOruka Therapeutics, Inc. | 12 | $605 |
| ABUSArbutus Biopharma Corp | 117 | $529 |
| HUMAHumacyte Inc. | 825 | $488 |
| NNVCNANOVIRICIDES, INC. | 500 | $477 |
| ALTAltimmune, Inc. | 141 | $440 |
| LXRXLEXICON PHARMACEUTICALS, INC. | 255 | $418 |
| ALECAlector, Inc. | 156 | $395 |
| ORICOric Pharmaceuticals, Inc. | 50 | $374 |
| RNACCartesian Therapeutics, Inc. | 57 | $364 |
| PVLAPALVELLA THERAPEUTICS, INC. | 3 | $361 |
| TRDAEntrada Therapeutics, Inc. | 17 | $229 |
| HCMHUTCHMED (China) Limited | 10 | $151 |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 153 | $123 |
| ACIUAC Immune SA | 43 | $120 |
| AARDAardvark Therapeutics, Inc. | 28 | $115 |
| OCGNOcugen, Inc. | 52 | $93 |
| TLXTelix Pharmaceuticals Limited | 9 | $83 |
| ATHEAlterity Therapeutics Limited | 22 | $80 |
| TVRDTvardi Therapeutics, Inc. | 23 | $69 |
| INOINOVIO PHARMACEUTICALS, INC. | 36 | $63 |
| BTAIBioXcel Therapeutics, Inc. | 25 | $31 |
| SCLXSCILEX HOLDING CO | 4 | $28 |
| FLNAFilana Therapeutics Inc. | 16 | $28 |
| IGCIGC Pharma, Inc. | 101 | $27 |
| SPROSpero Therapeutics, Inc. | 10 | $25 |
| EVOEvotec SE | 10 | $25 |
| APTOFAptose Biosciences Inc. | 10 | $17 |
| LPCNLipocine Inc. | 1 | $9 |
| PULMPulmatrix, Inc. | 7 | $9 |
| PLRXPLIANT THERAPEUTICS, INC. | 5 | $7 |
| ATAIAtai Beckley N.V. | 1 | $4 |
| AQSTAquestive Therapeutics, Inc. | 1 | $4 |
| CRDFCardiff Oncology, Inc. | 1 | $2 |
| LITSLite Strategy, Inc. | 2 | $2 |
| SERSerina Therapeutics, Inc. | 1 | $2 |
| GNTAGenenta Science S.p.A. | 3 | $2 |
| LIMNLIMINATUS PHARMA, INC. | 14 | $2 |
| IVVDInvivyd, Inc. | 1 | $1 |
| SBFMSUNSHINE BIOPHARMA INC. | 1 | $1 |