SIONNasdaq

Sionna Therapeutics, Inc.

Healthcare·Rare Disease·Phase 2·Waltham, MA, United States
Rare DiseaseRespiratory

Sionna Therapeutics, Inc. (SION): 8 pipeline candidates · 3 upcoming catalysts · ~15 mo cash runway · 2 clinical trials. Updated within the last hour.

6.4/10

BioSniper Score

6-factor signal · derived from public data

Cash Runway4.3

15.3 months

Financial Health9.9

D/E 0.06 · 0% dilution

Pipeline Maturity6.0

Lead: Phase 2

Pipeline Breadth10.0

8 candidates

Catalyst Momentum8.0

3 upcoming, next in ~12d

Insider Signal0.0

0 buys · 26 sells (180d)

A transparent, data-derived signal for Sionna Therapeutics, Inc.across cash runway, pipeline maturity & breadth, catalyst momentum and clinical/regulatory footprint. Each factor traces to tracked public filings — not an investment recommendation.

Key Financials

Market Cap

$1.6B

Cash

$64.3M

Quarterly Burn

$21.8M

Runway

15.3 mo

Revenue

Cash Runway vs Catalysts

Tracked catalysts land within the current projected cash runway.

Cash ends ~Sep 2027
Today~17 mo out
Catalyst within runway

Pipeline (8 candidates)

Upcoming Catalysts (3)

Institutional Holdings

Source: SEC Form 13F · as of Mar 2026

Institutional holders

119

Total value held

$1.43B

HolderSharesValue
ra capital management, l.p.9,905,045$397.1M
orbimed advisors llc3,530,702$141.5M
viking global investors lp3,195,181$128.1M
enavate sciences gp, llc2,478,030$99.3M
vanguard capital management llc2,058,994$82.5M
jennison associates llc1,451,220$58.2M
perceptive advisors llc1,316,878$52.8M
blackrock, inc.1,295,867$52.0M
citadel advisors llc1,166,931$46.8M
deerfield management company, l.p.970,590$38.9M

Showing top 10 of 119 institutional holders of Sionna Therapeutics, Inc.. Sign up for the full 13F holder list and quarter-by-quarter ownership history.

2 clinical trials·CEO: Mr. Michael Cloonan M.B.A.

Frequently asked questions

How many drug candidates are in Sionna Therapeutics, Inc.'s pipeline?

Sionna Therapeutics, Inc. (SION) has 8 pipeline candidates tracked by BioSniper across SEC filings and clinical trial registrations.

What is Sionna Therapeutics, Inc.'s lead drug candidate?

Sionna Therapeutics, Inc.'s most advanced tracked candidate is galicaftor (Phase 2) for Cystic fibrosis.

What is Sionna Therapeutics, Inc.'s next catalyst?

Sionna Therapeutics, Inc.'s next tracked catalyst is a Phase2_Topline event — "Phase 2 Readout: sion-719" — expected June 30, 2026.

What is Sionna Therapeutics, Inc.'s cash runway?

Based on its most recent reported cash balance and quarterly burn rate, Sionna Therapeutics, Inc. has approximately 15.3 months of cash runway.

What is Sionna Therapeutics, Inc.'s market capitalization?

Sionna Therapeutics, Inc.'s market capitalization is approximately $1.6B.

Get the full picture on Sionna Therapeutics, Inc.

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