| LLYELI LILLY & Co | 638,306 | $587.1M |
| AZNASTRAZENECA PLC | 1,992,762 | $386.0M |
| JNJJOHNSON & JOHNSON | 1,559,955 | $381.3M |
| GILDGILEAD SCIENCES, INC. | 1,624,637 | $226.4M |
| VRTXVERTEX PHARMACEUTICALS INC / MA | 377,013 | $168.4M |
| ABBVAbbVie Inc. | 660,576 | $143.7M |
| MRKMerck & Co., Inc. | 1,024,300 | $123.2M |
| MCKMcKesson Corporation | 129,037 | $111.7M |
| PFEPFIZER INC | 3,805,542 | $106.9M |
| AMGNAMGEN INC | 282,696 | $99.5M |
| BIIBBIOGEN INC. | 522,155 | $95.7M |
| BMYBRISTOL MYERS SQUIBB CO | 1,513,317 | $91.8M |
| CORCencora Inc. | 288,395 | $90.6M |
| ABTABBOTT LABORATORIES | 860,248 | $88.3M |
| UNHUnitedHealth Group Incorporated Common Stock (DE) | 276,466 | $74.8M |
| JAZZJazz Pharmaceuticals plc | 365,451 | $69.1M |
| REGNREGENERON PHARMACEUTICALS, INC. | 88,871 | $68.7M |
| PMPhilip Morris International Inc | 409,109 | $67.6M |
| CAHCardinal Health Inc. | 251,221 | $53.1M |
| ELVElevance Health Inc. | 162,031 | $47.4M |
| UTHRUNITED THERAPEUTICS Corp | 54,824 | $32.5M |
| GMOptec International, Inc. | 368,837 | $27.5M |
| INSMINSMED Inc | 152,366 | $24.9M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 74,920 | $24.8M |
| IDXXIDEXX LABORATORIES INC /DE | 37,147 | $20.9M |
| IQVIQVIA Holdings Inc. | 121,284 | $20.7M |
| INCYIncyte Corp. | 210,788 | $19.8M |
| TEVATeva Pharmaceutical Industries Limited | 595,032 | $17.9M |
| RPRXRoyalty Pharma plc | 373,042 | $17.9M |
| ZTSZoetis Inc. | 133,497 | $15.8M |
| NBIXNEUROCRINE BIOSCIENCES INC | 94,379 | $12.4M |
| GEHCGE HealthCare Technologies Inc. | 151,070 | $10.8M |
| QGENQIAGEN N.V. | 239,528 | $9.6M |
| VTRSViatris Inc | 627,641 | $8.5M |
| MRNAModerna, Inc. | 160,161 | $8.1M |
| RVMDREVOLUTION MEDICINES, INC. | 68,018 | $6.6M |
| DGXQuest Diagnostics Incorporated | 29,327 | $5.7M |
| ZBHZimmer Biomet Holdings Inc. | 61,651 | $5.6M |
| ELANElanco Animal Health Inc | 213,321 | $5.1M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 89,808 | $5.1M |
| GMEDGlobus Medical Inc. | 57,069 | $4.9M |
| BBIOBridgeBio Pharma, Inc. | 65,987 | $4.9M |
| MEDPMedpace Holdings Inc. | 9,429 | $4.5M |
| IONSIONIS PHARMACEUTICALS INC | 60,239 | $4.5M |
| ROIVRoivant Sciences Ltd. | 160,016 | $4.4M |
| WSTWest Pharmaceutical Services Inc. | 17,094 | $4.3M |
| CRSPCRISPR Therapeutics AG | 86,029 | $4.1M |
| GHGuardant Health Inc. | 43,696 | $4.0M |
| TECHBIO-TECHNE Corp | 66,140 | $3.5M |
| RGENREPLIGEN CORP | 26,381 | $3.1M |
| HALOHALOZYME THERAPEUTICS, INC. | 47,644 | $3.1M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 48,372 | $3.0M |
| CYTKCYTOKINETICS INC | 45,573 | $3.0M |
| CRLCHARLES RIVER LABORATORIES INTERNATIONAL, INC. | 17,095 | $2.9M |
| KYMRKymera Therapeutics, Inc. | 32,061 | $2.7M |
| PCVXVaxcyte, Inc. | 45,568 | $2.6M |
| MOHMolina Healthcare Inc | 19,685 | $2.6M |
| SDGRSchrodinger, Inc. | 221,321 | $2.5M |
| BEAMBeam Therapeutics Inc. | 102,129 | $2.4M |
| ALKSAlkermes plc. | 66,815 | $2.4M |
| LNTHLantheus Holdings, Inc. | 30,814 | $2.3M |
| BAXBaxter International Inc. | 136,934 | $2.3M |
| BNTXBioNTech SE | 24,844 | $2.2M |
| MDGLMADRIGAL PHARMACEUTICALS, INC. | 4,134 | $2.2M |
| DNLIDenali Therapeutics Inc. | 111,694 | $2.1M |
| DVADaVita Inc. | 13,892 | $2.1M |
| XENEXenon Pharmaceuticals Inc. | 35,204 | $2.0M |
| BCRXBIOCRYST PHARMACEUTICALS INC | 208,903 | $2.0M |
| PTCTPTC THERAPEUTICS, INC. | 26,965 | $1.8M |
| FOLDAMICUS THERAPEUTICS, INC. | 118,081 | $1.7M |
| AXSMAxsome Therapeutics, Inc. | 9,404 | $1.6M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 30,079 | $1.6M |
| MMSIMerit Medical Systems Inc. | 22,421 | $1.5M |
| VKTXViking Therapeutics, Inc. | 46,786 | $1.5M |
| MIRMMirum Pharmaceuticals, Inc. | 16,376 | $1.5M |
| INDVIndivior Pharmaceuticals, Inc. | 49,590 | $1.5M |
| SRRKScholar Rock Holding Corp | 29,178 | $1.4M |
| ACLXArcellx, Inc. | 12,314 | $1.4M |
| PTGXProtagonist Therapeutics, Inc | 13,412 | $1.4M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 15,598 | $1.4M |
| APGEApogee Therapeutics, Inc. | 15,916 | $1.3M |
| TGTXTG THERAPEUTICS, INC. | 40,211 | $1.3M |
| KRYSKrystal Biotech, Inc. | 5,139 | $1.3M |
| CPRXCATALYST PHARMACEUTICALS, INC. | 52,974 | $1.3M |
| PRAXPraxis Precision Medicines, Inc. | 4,049 | $1.3M |
| LQDALiquidia Corp | 34,093 | $1.3M |
| ALHCAlignment Healthcare Inc. | 65,254 | $1.1M |
| TWSTTwist Bioscience Corp | 24,096 | $1.1M |
| RIOTRiot Platforms, Inc. | 91,236 | $1.1M |
| APLSApellis Pharmaceuticals, Inc. | 27,921 | $1.1M |
| TVTXTravere Therapeutics, Inc. | 37,560 | $1.1M |
| RCUSArcus Biosciences, Inc. | 51,024 | $1.1M |
| NUVLNuvalent, Inc. | 10,492 | $1.1M |
| ARQTArcutis Biotherapeutics, Inc. | 42,131 | $993K |
| ZYMEZymeworks Inc. | 39,355 | $985K |
| CLDXCelldex Therapeutics, Inc. | 30,677 | $973K |
| IMNMImmunome Inc. | 44,488 | $973K |
| CRNXCrinetics Pharmaceuticals, Inc. | 26,439 | $960K |
| DYNDyne Therapeutics, Inc. | 52,152 | $946K |
| PBHPrestige Consumer Healthcare Inc. | 15,842 | $939K |
| PAHCPHIBRO ANIMAL HEALTH CORP | 16,778 | $928K |
| CORTCORCEPT THERAPEUTICS INC | 22,638 | $913K |
| ADMAADMA BIOLOGICS, INC. | 99,004 | $892K |
| NTLAIntellia Therapeutics, Inc. | 69,324 | $889K |
| COGTCogent Biosciences, Inc. | 22,857 | $880K |
| IDYAIDEAYA Biosciences, Inc. | 26,371 | $879K |
| ACADACADIA PHARMACEUTICALS INC | 38,947 | $867K |
| DAWNDay One Biopharmaceuticals, Inc. | 40,315 | $864K |
| RAREUltragenyx Pharmaceutical Inc. | 39,894 | $836K |
| AUPHAurinia Pharmaceuticals Inc. | 54,430 | $807K |
| VERAVera Therapeutics, Inc. | 19,897 | $800K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 23,620 | $799K |
| TERNTerns Pharmaceuticals, Inc. | 15,146 | $798K |
| SRPTSarepta Therapeutics, Inc. | 36,221 | $788K |
| CGONCG Oncology, Inc. | 11,609 | $786K |
| ARVNARVINAS, INC. | 73,853 | $783K |
| ERASErasca, Inc. | 47,918 | $775K |
| SHCSotera Health Company | 53,390 | $766K |
| HLFHerbalife Ltd. | 50,118 | $738K |
| VRDNViridian Therapeutics, Inc.\DE | 37,462 | $733K |
| KNSAKiniksa Pharmaceuticals International, plc | 15,111 | $728K |
| ACHCAcadia Healthcare Company Inc. | 30,950 | $724K |
| TRVITrevi Therapeutics, Inc. | 59,862 | $714K |
| NEOGNEOGEN CORP | 76,416 | $710K |
| SYRESpyre Therapeutics, Inc. | 13,955 | $704K |
| ADPTAdaptive Biotechnologies Corp | 49,622 | $689K |
| ARRYARRAY BIOPHARMA INC | 95,032 | $687K |
| AVNSAvanos Medical Inc. | 48,931 | $686K |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 20,921 | $670K |
| PBIPROVENTION BIO, INC. | 60,523 | $669K |
| RLAYRelay Therapeutics, Inc. | 66,739 | $664K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 214,851 | $660K |
| PRCTPROCEPT BioRobotics Corporation | 26,212 | $656K |
| INVAInnoviva, Inc. | 27,729 | $646K |
| NRIXNurix Therapeutics, Inc. | 40,928 | $634K |
| TARSTarsus Pharmaceuticals, Inc. | 8,899 | $624K |
| LGNDLigand Pharmaceuticals Incorporated | 3,121 | $623K |
| ARDXARDELYX, INC. | 103,494 | $620K |
| IBRXImmunityBio, Inc. | 80,269 | $616K |
| VCELVericel Corp | 19,049 | $613K |
| OSCROscar Health Inc. | 52,887 | $607K |
| INSPInspire Medical Systems Inc. | 11,604 | $599K |
| IMVTImmunovant, Inc. | 23,830 | $592K |
| SNDXSyndax Pharmaceuticals Inc | 24,739 | $578K |
| ICUIICU Medical Inc. | 4,431 | $572K |
| AMLXAmylyx Pharmaceuticals, Inc. | 40,790 | $567K |
| ABUSArbutus Biopharma Corp | 125,233 | $564K |
| XERSXeris Biopharma Holdings, Inc. | 93,302 | $541K |
| OGNOrganon & Co. | 90,134 | $540K |
| ANABANAPTYSBIO, INC | 9,599 | $532K |
| MLYSMineralys Therapeutics, Inc. | 19,641 | $532K |
| NEONeoGenomics Inc. | 71,242 | $529K |
| PGNYProgyny Inc. | 29,716 | $505K |
| KALVKalVista Pharmaceuticals, Inc. | 24,296 | $489K |
| NKTRNEKTAR THERAPEUTICS | 6,695 | $482K |
| BHCBausch Health Companies Inc. | 88,971 | $479K |
| EWTXEdgewise Therapeutics, Inc. | 14,739 | $464K |
| COLLCOLLEGIUM PHARMACEUTICAL, INC | 13,657 | $452K |
| MNKDMANNKIND CORP | 180,955 | $443K |
| BHVNBiohaven Ltd. | 51,123 | $433K |
| PRGOPERRIGO Co plc | 40,013 | $430K |
| ELVNEnliven Therapeutics, Inc. | 10,933 | $429K |
| ALMSALUMIS INC. | 18,386 | $405K |
| DNTHDianthus Therapeutics, Inc. /DE/ | 4,824 | $405K |
| DFTXDefinium Therapeutics Inc. | 20,868 | $394K |
| NVAXNOVAVAX INC | 47,980 | $391K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 12,840 | $390K |
| VIRVir Biotechnology, Inc. | 43,338 | $388K |
| KURAKura Oncology, Inc. | 46,363 | $377K |
| WVEWave Life Sciences Ltd. | 51,955 | $377K |
| HRMYHarmony Biosciences Holdings, Inc. | 13,369 | $374K |
| QDELQuidelOrtho Corp | 22,626 | $372K |
| CSTLCastle Biosciences Inc. | 15,028 | $369K |
| SLNOSOLENO THERAPEUTICS INC | 10,829 | $363K |
| TSHATaysha Gene Therapies, Inc. | 80,779 | $361K |
| IRONDisc Medicine, Inc. | 5,640 | $361K |
| MLTXMoonLake Immunotherapeutics | 19,229 | $358K |
| ANIPANI PHARMACEUTICALS INC | 4,285 | $330K |
| XNCRXencor Inc | 26,145 | $315K |
| STOKStoke Therapeutics, Inc. | 9,582 | $312K |
| TYRATyra Biosciences, Inc. | 8,038 | $308K |
| OCULOCULAR THERAPEUTIX, INC | 36,056 | $305K |
| QUREuniQure N.V. | 18,564 | $304K |
| AVBPArriVent BioPharma, Inc. | 13,106 | $302K |
| NVONovo Nordisk A/S | 8,186 | $301K |
| ANNXAnnexon, Inc. | 53,867 | $298K |
| PGENPRECIGEN, INC. | 71,764 | $278K |
| PHATPhathom Pharmaceuticals, Inc. | 24,992 | $278K |
| LEGNLegend Biotech Corp | 15,195 | $275K |
| CGEMCullinan Therapeutics, Inc. | 19,067 | $271K |
| CLOVClover Health Investments Corp. | 147,091 | $259K |
| SVRASavara Inc | 46,854 | $256K |
| GLUEMonte Rosa Therapeutics, Inc. | 15,254 | $251K |
| TBPHTheravance Biopharma, Inc. | 15,309 | $248K |
| SANASana Biotechnology, Inc. | 82,393 | $237K |
| CMPXCompass Therapeutics, Inc. | 43,914 | $232K |
| CTMXCytomX Therapeutics, Inc. | 47,988 | $226K |
| URGNUroGen Pharma Ltd. | 12,513 | $225K |
| TNGXTango Therapeutics, Inc. | 10,647 | $223K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 63,430 | $223K |
| NUVBNuvation Bio Inc. | 50,230 | $215K |
| PCRXPacira BioSciences, Inc. | 8,982 | $203K |
| ORICOric Pharmaceuticals, Inc. | 15,432 | $196K |
| MYGNMYRIAD GENETICS INC | 39,702 | $179K |
| FLGTFulgent Genetics Inc. | 10,878 | $173K |
| JANXJanux Therapeutics, Inc. | 12,357 | $172K |
| OLMAOlema Pharmaceuticals, Inc. | 11,305 | $169K |
| TLRYTilray Brands, Inc. | 25,765 | $167K |
| ATAIAtai Beckley N.V. | 46,375 | $164K |
| MDXGMiMedx Group Inc | 39,713 | $157K |
| GERNGERON CORP | 103,230 | $154K |
| AMPHAmphastar Pharmaceuticals, Inc. | 7,783 | $152K |
| ZBIOZenas BioPharma, Inc. | 6,777 | $132K |
| BCAXBicara Therapeutics Inc. | 6,400 | $127K |
| PHVSPharvaris N.V. | 3,979 | $112K |
| SPRYARS Pharmaceuticals, Inc. | 11,662 | $94K |
| CRMDCorMedix Inc. | 13,588 | $92K |
| CRONCronos Group Inc. | 36,493 | $92K |
| RDYDR REDDYS LABORATORIES LTD | 6,341 | $88K |
| ICLRICON plc | 615 | $68K |
| PRMEPrime Medicine, Inc. | 18,225 | $63K |
| OPKOPKO HEALTH, INC. | 55,140 | $63K |
| LENZLENZ Therapeutics, Inc. | 6,099 | $56K |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 747 | $41K |
| ORKAOruka Therapeutics, Inc. | 496 | $24K |
| DNAGinkgo Bioworks Holdings Inc. | 3,700 | $23K |
| KODKodiak Sciences Inc. | 539 | $21K |
| RGNXREGENXBIO Inc. | 2,390 | $20K |
| BIOABioAge Labs, Inc. | 1,082 | $19K |
| ACRSAclaris Therapeutics, Inc. | 5,006 | $19K |
| SOPHSOPHiA GENETICS SA | 3,755 | $19K |
| TRDAEntrada Therapeutics, Inc. | 1,417 | $18K |
| DSGNDesign Therapeutics, Inc. | 1,594 | $17K |
| RAPPRapport Therapeutics, Inc. | 513 | $16K |
| SIONSionna Therapeutics, Inc. | 371 | $15K |
| KYTXKyverna Therapeutics, Inc. | 1,629 | $14K |
| MBXMBX Biosciences, Inc. | 470 | $14K |
| INBXInhibrx Biosciences, Inc. | 194 | $13K |
| RCKTRocket Pharmaceuticals Inc. | 3,557 | $13K |
| SEPNSepterna, Inc. | 508 | $12K |
| REPLReplimune Group, Inc. | 1,586 | $12K |
| CMPSCOMPASS Pathways plc | 2,192 | $12K |
| ABVXAbivax SA | 105 | $12K |
| ENTAENANTA PHARMACEUTICALS INC | 906 | $11K |
| IRWDIRONWOOD PHARMACEUTICALS INC | 3,079 | $11K |
| MAZEMaze Therapeutics, Inc. | 361 | $11K |
| ESPREsperion Therapeutics, Inc. | 3,864 | $11K |
| GPCRStructure Therapeutics Inc. | 212 | $10K |
| FULCFulcrum Therapeutics, Inc. | 1,182 | $9K |
| RIGLRIGEL PHARMACEUTICALS INC | 335 | $9K |
| LYELLyell Immunopharma, Inc. | 447 | $9K |
| OMEROMEROS CORP | 793 | $8K |
| RANIRani Therapeutics Holdings, Inc. | 10,502 | $8K |
| KROSKeros Therapeutics, Inc. | 699 | $8K |
| IVVDInvivyd, Inc. | 5,157 | $7K |
| UPBUpstream Bio, Inc. | 477 | $4K |
| PEPGPepGen Inc. | 2,006 | $4K |
| RNAAtrium Therapeutics Inc. | 49 | $655 |
| SCLXSCILEX HOLDING CO | 44 | $293 |
| MESOMesoblast Limited | 7 | $108 |
| TECXTectonic Therapeutic, Inc. | 3 | $93 |
| AVXLANAVEX LIFE SCIENCES CORP. | 19 | $58 |
| TKNOAlpha Teknova, Inc. | 17 | $49 |
| PLRXPLIANT THERAPEUTICS, INC. | 36 | $45 |
| CNTACentessa Pharmaceuticals plc | 1 | $40 |
| ALVOAlvotech | 11 | $38 |
| SKYESkye Bioscience, Inc. | 52 | $32 |
| OFIXOrthofix Medical Inc. Common Stock (DE) | 1 | $11 |
| MXCTMaxCyte Inc. | 14 | $10 |
| FDMT4D Molecular Therapeutics, Inc. | 1 | $9 |
| BTAIBioXcel Therapeutics, Inc. | 2 | $3 |