| LLYELI LILLY & Co | 1,357,624 | $1.25B |
| JNJJOHNSON & JOHNSON | 2,492,186 | $609.2M |
| ABBVAbbVie Inc. | 2,328,944 | $506.5M |
| ABTABBOTT LABORATORIES | 2,707,901 | $278.0M |
| UNHUnitedHealth Group Incorporated Common Stock (DE) | 1,012,177 | $273.9M |
| AMGNAMGEN INC | 667,057 | $234.7M |
| MRKMerck & Co., Inc. | 1,554,747 | $187.0M |
| GILDGILEAD SCIENCES, INC. | 856,921 | $119.4M |
| PFEPFIZER INC | 3,863,894 | $108.5M |
| PMPhilip Morris International Inc | 646,151 | $106.8M |
| BMYBRISTOL MYERS SQUIBB CO | 1,329,743 | $80.6M |
| MCKMcKesson Corporation | 79,746 | $69.0M |
| NVSNovartis AG | 268,858 | $41.1M |
| AZNASTRAZENECA PLC | 139,073 | $27.4M |
| GEHCGE HealthCare Technologies Inc. | 347,368 | $24.7M |
| AXSMAxsome Therapeutics, Inc. | 131,414 | $22.2M |
| CORCencora Inc. | 47,276 | $14.9M |
| ELVElevance Health Inc. | 47,471 | $13.9M |
| VRTXVERTEX PHARMACEUTICALS INC / MA | 29,781 | $13.3M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 228,508 | $12.6M |
| CAHCardinal Health Inc. | 53,227 | $11.2M |
| TAKTakeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock) | 510,225 | $9.4M |
| NVONovo Nordisk A/S | 251,687 | $9.2M |
| IDXXIDEXX LABORATORIES INC /DE | 15,200 | $8.5M |
| TECHBIO-TECHNE Corp | 149,030 | $7.8M |
| GMOptec International, Inc. | 101,589 | $7.6M |
| ZTSZoetis Inc. | 63,950 | $7.6M |
| ZBHZimmer Biomet Holdings Inc. | 76,902 | $7.0M |
| BIIBBIOGEN INC. | 31,223 | $5.7M |
| TEVATeva Pharmaceutical Industries Limited | 181,965 | $5.5M |
| IQVIQVIA Holdings Inc. | 31,459 | $5.4M |
| REGNREGENERON PHARMACEUTICALS, INC. | 5,628 | $4.3M |
| SNYSanofi | 87,155 | $4.2M |
| DGXQuest Diagnostics Incorporated | 20,905 | $4.1M |
| GHGuardant Health Inc. | 40,703 | $3.8M |
| VTRSViatris Inc | 243,816 | $3.3M |
| MEDPMedpace Holdings Inc. | 6,027 | $2.9M |
| GMABGenmab A/S | 95,548 | $2.6M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 7,381 | $2.4M |
| RGENREPLIGEN CORP | 18,869 | $2.2M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 34,683 | $2.2M |
| ARGXARGENX SE | 2,823 | $2.1M |
| RDYDR REDDYS LABORATORIES LTD | 146,928 | $2.0M |
| QGENQIAGEN N.V. | 47,154 | $1.9M |
| WSTWest Pharmaceutical Services Inc. | 7,332 | $1.8M |
| ADPTAdaptive Biotechnologies Corp | 116,456 | $1.6M |
| MOHMolina Healthcare Inc | 9,904 | $1.3M |
| SUNSUNSET ISLAND GROUP | 18,884 | $1.2M |
| INSMINSMED Inc | 7,377 | $1.2M |
| BAXBaxter International Inc. | 70,002 | $1.2M |
| ALHCAlignment Healthcare Inc. | 65,227 | $1.1M |
| GMEDGlobus Medical Inc. | 13,081 | $1.1M |
| VCELVericel Corp | 34,178 | $1.1M |
| CRLCHARLES RIVER LABORATORIES INTERNATIONAL, INC. | 6,247 | $1.1M |
| ELANElanco Animal Health Inc | 41,990 | $1.0M |
| ICUIICU Medical Inc. | 7,673 | $991K |
| ICLRICON plc | 8,953 | $991K |
| UTHRUNITED THERAPEUTICS Corp | 1,578 | $936K |
| TWSTTwist Bioscience Corp | 17,598 | $836K |
| BBIOBridgeBio Pharma, Inc. | 11,083 | $823K |
| MRNAModerna, Inc. | 13,480 | $685K |
| HALOHALOZYME THERAPEUTICS, INC. | 9,388 | $607K |
| NRCNational Research Corporation Common Stock (Delaware) | 32,673 | $555K |
| INCYIncyte Corp. | 5,626 | $530K |
| RPRXRoyalty Pharma plc | 10,864 | $521K |
| FMSFresenius Medical Care AG American Depositary Shares (Each representing 1/2 of an Ordinary Share) | 23,008 | $519K |
| LNTHLantheus Holdings, Inc. | 6,713 | $509K |
| ONCBeOne Medicines Ltd. | 1,708 | $507K |
| KMTSKestra Medical Technologies Ltd. | 25,139 | $501K |
| CRSPCRISPR Therapeutics AG | 10,503 | $500K |
| PRAXPraxis Precision Medicines, Inc. | 1,539 | $496K |
| COGTCogent Biosciences, Inc. | 12,210 | $470K |
| NBIXNEUROCRINE BIOSCIENCES INC | 3,388 | $446K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 14,433 | $439K |
| MDGLMADRIGAL PHARMACEUTICALS, INC. | 835 | $437K |
| DVADaVita Inc. | 2,827 | $434K |
| PTGXProtagonist Therapeutics, Inc | 3,914 | $413K |
| DNTHDianthus Therapeutics, Inc. /DE/ | 4,722 | $396K |
| IONSIONIS PHARMACEUTICALS INC | 5,047 | $379K |
| JAZZJazz Pharmaceuticals plc | 1,971 | $373K |
| RVMDREVOLUTION MEDICINES, INC. | 3,828 | $372K |
| BEAMBeam Therapeutics Inc. | 14,672 | $350K |
| PBHPrestige Consumer Healthcare Inc. | 5,422 | $321K |
| NUVLNuvalent, Inc. | 2,770 | $284K |
| TERNTerns Pharmaceuticals, Inc. | 5,190 | $274K |
| IMNMImmunome Inc. | 12,312 | $269K |
| CYTKCYTOKINETICS INC | 4,050 | $267K |
| CRNXCrinetics Pharmaceuticals, Inc. | 7,061 | $256K |
| VKTXViking Therapeutics, Inc. | 7,623 | $248K |
| LGNDLigand Pharmaceuticals Incorporated | 1,211 | $242K |
| PRCTPROCEPT BioRobotics Corporation | 9,576 | $239K |
| ORKAOruka Therapeutics, Inc. | 4,865 | $239K |
| RIOTRiot Platforms, Inc. | 17,273 | $213K |
| MMSIMerit Medical Systems Inc. | 3,080 | $212K |
| BMRNBIOMARIN PHARMACEUTICAL INC | 3,673 | $207K |
| KYMRKymera Therapeutics, Inc. | 2,303 | $192K |
| GRFSGrifols S.A. | 23,703 | $190K |
| AUPHAurinia Pharmaceuticals Inc. | 12,004 | $178K |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 5,474 | $175K |
| ROIVRoivant Sciences Ltd. | 5,833 | $162K |
| ACHCAcadia Healthcare Company Inc. | 6,851 | $160K |
| BNTXBioNTech SE | 1,599 | $142K |
| NKTRNEKTAR THERAPEUTICS | 1,916 | $138K |
| NEOGNEOGEN CORP | 13,602 | $126K |
| SRRKScholar Rock Holding Corp | 2,549 | $125K |
| LEGNLegend Biotech Corp | 6,723 | $122K |
| INSPInspire Medical Systems Inc. | 2,303 | $119K |
| NVAXNOVAVAX INC | 13,170 | $107K |
| SNDXSyndax Pharmaceuticals Inc | 4,573 | $107K |
| ACLXArcellx, Inc. | 909 | $104K |
| PCVXVaxcyte, Inc. | 1,642 | $95K |
| SLDBSolid Biosciences Inc. | 13,218 | $95K |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 1,840 | $95K |
| EWTXEdgewise Therapeutics, Inc. | 2,973 | $94K |
| TGTXTG THERAPEUTICS, INC. | 2,797 | $93K |
| ANABANAPTYSBIO, INC | 1,635 | $91K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 1,041 | $91K |
| IDYAIDEAYA Biosciences, Inc. | 2,498 | $83K |
| OSCROscar Health Inc. | 7,088 | $81K |
| IBRXImmunityBio, Inc. | 10,501 | $81K |
| SHCSotera Health Company | 5,535 | $79K |
| SRPTSarepta Therapeutics, Inc. | 3,636 | $79K |
| SVRASavara Inc | 14,252 | $78K |
| OGNOrganon & Co. | 12,916 | $77K |
| IRONDisc Medicine, Inc. | 1,185 | $76K |
| MIRMMirum Pharmaceuticals, Inc. | 805 | $74K |
| PTCTPTC THERAPEUTICS, INC. | 1,037 | $71K |
| CRBUCaribou Biosciences, Inc. | 34,265 | $65K |
| APGEApogee Therapeutics, Inc. | 748 | $63K |
| KRYSKrystal Biotech, Inc. | 234 | $60K |
| VRDNViridian Therapeutics, Inc.\DE | 2,905 | $57K |
| APLSApellis Pharmaceuticals, Inc. | 1,380 | $56K |
| ARRYARRAY BIOPHARMA INC | 7,461 | $54K |
| OMEROMEROS CORP | 5,103 | $54K |
| RLAYRelay Therapeutics, Inc. | 5,232 | $52K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 16,940 | $52K |
| WVEWave Life Sciences Ltd. | 7,025 | $51K |
| AVTXAvalo Therapeutics, Inc. | 3,387 | $51K |
| RAREUltragenyx Pharmaceutical Inc. | 2,315 | $48K |
| PRGOPERRIGO Co plc | 4,209 | $45K |
| SLNOSOLENO THERAPEUTICS INC | 1,339 | $45K |
| CPRXCATALYST PHARMACEUTICALS, INC. | 1,789 | $44K |
| KNSAKiniksa Pharmaceuticals International, plc | 913 | $44K |
| CGONCG Oncology, Inc. | 643 | $44K |
| MLTXMoonLake Immunotherapeutics | 2,323 | $43K |
| PBIPROVENTION BIO, INC. | 3,437 | $38K |
| FOLDAMICUS THERAPEUTICS, INC. | 2,438 | $35K |
| KURAKura Oncology, Inc. | 4,332 | $35K |
| TECXTectonic Therapeutic, Inc. | 1,136 | $35K |
| SMMTSummit Therapeutics Inc. | 1,850 | $35K |
| ALKSAlkermes plc. | 933 | $33K |
| DMACDiaMedica Therapeutics Inc. | 4,522 | $31K |
| ANIPANI PHARMACEUTICALS INC | 394 | $30K |
| ARDXARDELYX, INC. | 5,058 | $30K |
| MANEVeradermics Incorporated | 470 | $30K |
| AVNSAvanos Medical Inc. | 2,117 | $30K |
| AMLXAmylyx Pharmaceuticals, Inc. | 2,063 | $29K |
| DNAGinkgo Bioworks Holdings Inc. | 4,633 | $28K |
| AVBPArriVent BioPharma, Inc. | 1,222 | $28K |
| TVTXTravere Therapeutics, Inc. | 915 | $27K |
| CAICaris Life Sciences Inc. | 1,511 | $27K |
| IVVDInvivyd, Inc. | 20,500 | $27K |
| UTMDUtah Medical Products Inc. | 414 | $26K |
| REPLReplimune Group, Inc. | 3,339 | $26K |
| CLDXCelldex Therapeutics, Inc. | 772 | $24K |
| CORTCORCEPT THERAPEUTICS INC | 590 | $24K |
| QUREuniQure N.V. | 1,402 | $23K |
| ZBIOZenas BioPharma, Inc. | 994 | $19K |
| PCRXPacira BioSciences, Inc. | 859 | $19K |
| ZLABZai Lab Ltd | 1,023 | $19K |
| QDELQuidelOrtho Corp | 1,149 | $19K |
| INVAInnoviva, Inc. | 795 | $19K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 542 | $18K |
| RGNXREGENXBIO Inc. | 2,178 | $18K |
| DYNDyne Therapeutics, Inc. | 965 | $17K |
| AVXLANAVEX LIFE SCIENCES CORP. | 5,670 | $17K |
| DNLIDenali Therapeutics Inc. | 902 | $17K |
| BHVNBiohaven Ltd. | 2,018 | $17K |
| EBSEmergent BioSolutions Inc. | 1,976 | $16K |
| CRVSCorvus Pharmaceuticals, Inc. | 1,103 | $16K |
| XENEXenon Pharmaceuticals Inc. | 272 | $16K |
| NUSNu Skin Enterprises Inc. | 2,172 | $16K |
| PGNYProgyny Inc. | 869 | $15K |
| INBXInhibrx Biosciences, Inc. | 219 | $15K |
| KALVKalVista Pharmaceuticals, Inc. | 708 | $14K |
| SPRYARS Pharmaceuticals, Inc. | 1,519 | $12K |
| GERNGERON CORP | 8,000 | $12K |
| WHWKWhitehawk Therapeutics, Inc. | 3,333 | $11K |
| VIRVir Biotechnology, Inc. | 1,180 | $11K |
| ALMSALUMIS INC. | 464 | $10K |
| ABSIAbsci Corporation | 3,274 | $10K |
| ZVRAZEVRA THERAPEUTICS, INC. | 1,034 | $10K |
| AQSTAquestive Therapeutics, Inc. | 2,283 | $9K |
| ARVNARVINAS, INC. | 881 | $9K |
| DAWNDay One Biopharmaceuticals, Inc. | 414 | $9K |
| IMVTImmunovant, Inc. | 356 | $9K |
| ZYMEZymeworks Inc. | 352 | $9K |
| RCUSArcus Biosciences, Inc. | 403 | $9K |
| STOKStoke Therapeutics, Inc. | 265 | $9K |
| HCMHUTCHMED (China) Limited | 573 | $9K |
| HRMYHarmony Biosciences Holdings, Inc. | 305 | $9K |
| MBXMBX Biosciences, Inc. | 284 | $8K |
| MLYSMineralys Therapeutics, Inc. | 302 | $8K |
| IMCRImmunocore Holdings plc | 264 | $8K |
| OLMAOlema Pharmaceuticals, Inc. | 511 | $8K |
| MYGNMYRIAD GENETICS INC | 1,680 | $8K |
| NTLAIntellia Therapeutics, Inc. | 583 | $7K |
| XNCRXencor Inc | 605 | $7K |
| SDGRSchrodinger, Inc. | 630 | $7K |
| ABUSArbutus Biopharma Corp | 1,588 | $7K |
| CGEMCullinan Therapeutics, Inc. | 502 | $7K |
| ACHAccendra Health Inc. | 3,000 | $7K |
| NUVBNuvation Bio Inc. | 1,581 | $7K |
| ELVNEnliven Therapeutics, Inc. | 167 | $7K |
| RCKTRocket Pharmaceuticals Inc. | 1,824 | $7K |
| MESOMesoblast Limited | 410 | $6K |
| AMPHAmphastar Pharmaceuticals, Inc. | 318 | $6K |
| JANXJanux Therapeutics, Inc. | 447 | $6K |
| MGXMetagenomi Therapeutics, Inc. | 4,500 | $6K |
| TBPHTheravance Biopharma, Inc. | 368 | $6K |
| COLLCOLLEGIUM PHARMACEUTICAL, INC | 179 | $6K |
| ABVXAbivax SA | 51 | $6K |
| UPBUpstream Bio, Inc. | 590 | $5K |
| LRMRLarimar Therapeutics, Inc. | 1,175 | $5K |
| ADMAADMA BIOLOGICS, INC. | 575 | $5K |
| BNTCBenitec Biopharma Inc. | 482 | $5K |
| CRDFCardiff Oncology, Inc. | 3,109 | $5K |
| BCAXBicara Therapeutics Inc. | 251 | $5K |
| SYRESpyre Therapeutics, Inc. | 97 | $5K |
| ERASErasca, Inc. | 295 | $5K |
| SEPNSepterna, Inc. | 197 | $5K |
| TSHATaysha Gene Therapies, Inc. | 1,007 | $5K |
| PVLAPALVELLA THERAPEUTICS, INC. | 35 | $4K |
| GLPGGalapagos NV | 144 | $4K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 1,212 | $4K |
| VERAVera Therapeutics, Inc. | 105 | $4K |
| PRTAPROTHENA CORP PUBLIC LTD CO | 418 | $4K |
| CYRXCryoport, Inc. | 486 | $4K |
| RNAAtrium Therapeutics Inc. | 297 | $4K |
| OCULOCULAR THERAPEUTIX, INC | 468 | $4K |
| MNPRMonopar Therapeutics | 72 | $4K |
| NRIXNurix Therapeutics, Inc. | 249 | $4K |
| MISTMilestone Pharmaceuticals Inc. | 3,200 | $4K |
| OFIXOrthofix Medical Inc. Common Stock (DE) | 331 | $4K |
| TARSTarsus Pharmaceuticals, Inc. | 54 | $4K |
| BIOABioAge Labs, Inc. | 216 | $4K |
| CADLCandel Therapeutics, Inc. | 731 | $4K |
| ACADACADIA PHARMACEUTICALS INC | 157 | $3K |
| ARQTArcutis Biotherapeutics, Inc. | 142 | $3K |
| CLOVClover Health Investments Corp. | 1,893 | $3K |
| PHATPhathom Pharmaceuticals, Inc. | 295 | $3K |
| ARCTArcturus Therapeutics Holdings Inc. | 423 | $3K |
| MRVIMARAVAI LIFESCIENCES HOLDINGS, INC. | 1,021 | $3K |
| SCYXSCYNEXIS INC | 3,100 | $3K |
| ESPREsperion Therapeutics, Inc. | 1,030 | $3K |
| ALTAltimmune, Inc. | 890 | $3K |
| PAHCPHIBRO ANIMAL HEALTH CORP | 45 | $2K |
| ANROAlto Neuroscience, Inc. | 110 | $2K |
| ABOSAcumen Pharmaceuticals, Inc. | 1,000 | $2K |
| CSTLCastle Biosciences Inc. | 92 | $2K |
| BBNXBeta Bionics Inc. | 221 | $2K |
| USNAUSANA HEALTH SCIENCES INC | 126 | $2K |
| ORICOric Pharmaceuticals, Inc. | 173 | $2K |
| PTNPALATIN TECHNOLOGIES INC | 125 | $2K |
| HLFHerbalife Ltd. | 147 | $2K |
| ABCLAbCellera Biologics Inc. | 611 | $2K |
| XOMAXOMA Royalty Corporation | 67 | $2K |
| SIONSionna Therapeutics, Inc. | 51 | $2K |
| SANASana Biotechnology, Inc. | 694 | $2K |
| ZURAZura Bio Ltd | 318 | $2K |
| VERUVERU INC. | 750 | $2K |
| ASMBASSEMBLY BIOSCIENCES, INC. | 59 | $2K |
| RNTXRein Therapeutics, Inc. | 1,250 | $2K |
| HUMAHumacyte Inc. | 2,500 | $2K |
| NEONeoGenomics Inc. | 204 | $2K |
| CRONCronos Group Inc. | 600 | $2K |
| CATXPerspective Therapeutics, Inc. | 344 | $1K |
| ALLOAllogene Therapeutics, Inc. | 572 | $1K |
| FLGTFulgent Genetics Inc. | 84 | $1K |
| PBYIPUMA BIOTECHNOLOGY, INC. | 200 | $1K |
| BCRXBIOCRYST PHARMACEUTICALS INC | 131 | $1K |
| NATRNATURES SUNSHINE PRODUCTS INC | 51 | $1K |
| TLSATiziana Life Sciences Ltd | 1,000 | $1K |
| LYELLyell Immunopharma, Inc. | 58 | $1K |
| SNWVSANUWAVE Health Inc. | 66 | $1K |
| ANIXAnixa Biosciences Inc | 400 | $1K |
| KODKodiak Sciences Inc. | 27 | $1K |
| TRVITrevi Therapeutics, Inc. | 85 | $1K |
| TNGXTango Therapeutics, Inc. | 48 | $1K |
| INDVIndivior Pharmaceuticals, Inc. | 32 | $975 |
| TRDAEntrada Therapeutics, Inc. | 70 | $883 |
| LONALeonaBio, Inc. | 81 | $833 |
| LQDALiquidia Corp | 21 | $793 |
| GYREGYRE THERAPEUTICS, INC. | 98 | $683 |
| NAGENiagen Bioscience, Inc. | 148 | $653 |
| DSGNDesign Therapeutics, Inc. | 61 | $649 |
| NGNENeurogene Inc. | 30 | $605 |
| AURAAura Biosciences, Inc. | 80 | $535 |
| TXMDTherapeuticsMD, Inc. | 246 | $497 |
| GPCRStructure Therapeutics Inc. | 10 | $482 |
| ETONEton Pharmaceuticals, Inc. | 19 | $469 |
| BVSBioventus Inc. | 51 | $466 |
| JSPRJasper Therapeutics Inc. | 500 | $438 |
| ANNXAnnexon, Inc. | 77 | $427 |
| TYRATyra Biosciences, Inc. | 11 | $421 |
| CMPXCompass Therapeutics, Inc. | 77 | $407 |
| KROSKeros Therapeutics, Inc. | 35 | $386 |
| GLSIGreenwich LifeSciences, Inc. | 15 | $360 |
| SPROSpero Therapeutics, Inc. | 151 | $353 |
| AVIRAtea Pharmaceuticals, Inc. | 64 | $344 |
| FDMT4D Molecular Therapeutics, Inc. | 35 | $326 |
| MAZEMaze Therapeutics, Inc. | 9 | $269 |
| JBIOJade Biosciences, Inc. | 15 | $211 |
| FULCFulcrum Therapeutics, Inc. | 26 | $199 |
| GLUEMonte Rosa Therapeutics, Inc. | 12 | $197 |
| ORGOOrganogenesis Holdings Inc. | 76 | $180 |
| INNVINNOVUS PHARMACEUTICALS, INC. | 22 | $176 |
| NPCENeuropace Inc. | 13 | $171 |
| RAPPRapport Therapeutics, Inc. | 5 | $156 |
| MGTXMeiraGTx Holdings plc | 17 | $147 |
| MNKDMANNKIND CORP | 60 | $147 |
| LENZLENZ Therapeutics, Inc. | 16 | $146 |
| PRMEPrime Medicine, Inc. | 33 | $115 |
| CGCCanopy Growth Corp | 107 | $102 |
| CLNNClene Inc. | 20 | $99 |
| SNOASonoma Pharmaceuticals, Inc. | 25 | $53 |
| SCLXSCILEX HOLDING CO | 8 | $53 |
| ENLVEnlivex Ltd. | 50 | $47 |
| NNVCNANOVIRICIDES, INC. | 43 | $39 |
| CLRBCellectar Biosciences, Inc. | 3 | $8 |
| KYNBKYNTRA BIO INC. | 1 | $7 |
| MREOMereo BioPharma Group plc | 13 | $4 |
| SGMOSANGAMO THERAPEUTICS, INC | 11 | $3 |
| BTTCBlack Titan Corporation | 1 | $1 |
| BTAIBioXcel Therapeutics, Inc. | 1 | $1 |