| REGNREGENERON PHARMACEUTICALS, INC. | 1,486 | $1.1M |
| GILDGILEAD SCIENCES, INC. | 5,436 | $758K |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 13,121 | $724K |
| BMRNBIOMARIN PHARMACEUTICAL INC | 7,865 | $444K |
| INCYIncyte Corp. | 4,540 | $427K |
| EXELEXELIXIS, INC. | 6,941 | $298K |
| SNYSanofi | 3,909 | $188K |
| ADPTAdaptive Biotechnologies Corp | 13,300 | $185K |
| JAZZJazz Pharmaceuticals plc | 883 | $167K |
| LGNDLigand Pharmaceuticals Incorporated | 434 | $87K |
| TEVATeva Pharmaceutical Industries Limited | 2,452 | $74K |
| GMABGenmab A/S | 2,514 | $67K |
| ROIVRoivant Sciences Ltd. | 1,907 | $53K |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 159 | $53K |
| ABCLAbCellera Biologics Inc. | 14,495 | $51K |
| MRNAModerna, Inc. | 772 | $39K |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 354 | $22K |
| OGNOrganon & Co. | 3,695 | $22K |
| ARGXARGENX SE | 30 | $22K |
| ADMAADMA BIOLOGICS, INC. | 2,360 | $21K |
| BBIOBridgeBio Pharma, Inc. | 271 | $20K |
| TERNTerns Pharmaceuticals, Inc. | 370 | $20K |
| TGTXTG THERAPEUTICS, INC. | 433 | $14K |
| CYTKCYTOKINETICS INC | 205 | $14K |
| ARQTArcutis Biotherapeutics, Inc. | 565 | $13K |
| PTCTPTC THERAPEUTICS, INC. | 188 | $13K |
| INSMINSMED Inc | 72 | $12K |
| AXSMAxsome Therapeutics, Inc. | 67 | $11K |
| PTGXProtagonist Therapeutics, Inc | 107 | $11K |
| ABVXAbivax SA | 100 | $11K |
| COGTCogent Biosciences, Inc. | 286 | $11K |
| PCVXVaxcyte, Inc. | 189 | $11K |
| SRRKScholar Rock Holding Corp | 204 | $10K |
| STOKStoke Therapeutics, Inc. | 291 | $9K |
| FOLDAMICUS THERAPEUTICS, INC. | 635 | $9K |
| ANABANAPTYSBIO, INC | 165 | $9K |
| ALMSALUMIS INC. | 410 | $9K |
| KNSAKiniksa Pharmaceuticals International, plc | 184 | $9K |
| TVTXTravere Therapeutics, Inc. | 252 | $7K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 86 | $7K |
| APGEApogee Therapeutics, Inc. | 87 | $7K |
| NUVLNuvalent, Inc. | 67 | $7K |
| ARDXARDELYX, INC. | 1,016 | $6K |
| DAWNDay One Biopharmaceuticals, Inc. | 282 | $6K |
| LQDALiquidia Corp | 151 | $6K |
| DNLIDenali Therapeutics Inc. | 288 | $6K |
| DFTXDefinium Therapeutics Inc. | 292 | $6K |
| GRFSGrifols S.A. | 653 | $5K |
| SYRESpyre Therapeutics, Inc. | 99 | $5K |
| NTLAIntellia Therapeutics, Inc. | 389 | $5K |
| RGNXREGENXBIO Inc. | 551 | $5K |
| INVAInnoviva, Inc. | 189 | $4K |
| XERSXeris Biopharma Holdings, Inc. | 759 | $4K |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 80 | $4K |
| HRMYHarmony Biosciences Holdings, Inc. | 145 | $4K |
| RVMDREVOLUTION MEDICINES, INC. | 41 | $4K |
| GERNGERON CORP | 2,586 | $4K |
| CLDXCelldex Therapeutics, Inc. | 119 | $4K |
| KURAKura Oncology, Inc. | 425 | $3K |
| ACADACADIA PHARMACEUTICALS INC | 152 | $3K |
| OLMAOlema Pharmaceuticals, Inc. | 225 | $3K |
| RCKTRocket Pharmaceuticals Inc. | 932 | $3K |
| RCUSArcus Biosciences, Inc. | 146 | $3K |
| BHVNBiohaven Ltd. | 352 | $3K |
| ARVNARVINAS, INC. | 262 | $3K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 789 | $3K |
| OCULOCULAR THERAPEUTIX, INC | 320 | $3K |
| IMVTImmunovant, Inc. | 109 | $3K |
| CGEMCullinan Therapeutics, Inc. | 189 | $3K |
| VRDNViridian Therapeutics, Inc.\DE | 136 | $3K |
| HROWHARROW, INC. | 75 | $3K |
| IRONDisc Medicine, Inc. | 41 | $3K |
| PBYIPUMA BIOTECHNOLOGY, INC. | 406 | $3K |
| KROSKeros Therapeutics, Inc. | 230 | $3K |
| IBRXImmunityBio, Inc. | 325 | $2K |
| ANNXAnnexon, Inc. | 437 | $2K |
| KALVKalVista Pharmaceuticals, Inc. | 110 | $2K |
| SIGASIGA TECHNOLOGIES INC | 391 | $2K |
| ZYMEZymeworks Inc. | 80 | $2K |
| ANIPANI PHARMACEUTICALS INC | 26 | $2K |
| TNGXTango Therapeutics, Inc. | 86 | $2K |
| DNTHDianthus Therapeutics, Inc. /DE/ | 21 | $2K |
| CMPSCOMPASS Pathways plc | 304 | $2K |
| LENZLENZ Therapeutics, Inc. | 180 | $2K |
| NUVBNuvation Bio Inc. | 381 | $2K |
| VCELVericel Corp | 50 | $2K |
| SLNOSOLENO THERAPEUTICS INC | 47 | $2K |
| ELVNEnliven Therapeutics, Inc. | 40 | $2K |
| LONALeonaBio, Inc. | 150 | $2K |
| AVXLANAVEX LIFE SCIENCES CORP. | 484 | $1K |
| BEAMBeam Therapeutics Inc. | 62 | $1K |
| CMPXCompass Therapeutics, Inc. | 279 | $1K |
| ABSIAbsci Corporation | 492 | $1K |
| KODKodiak Sciences Inc. | 37 | $1K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 40 | $1K |
| LRMRLarimar Therapeutics, Inc. | 287 | $1K |
| ORKAOruka Therapeutics, Inc. | 26 | $1K |
| TNXPTonix Pharmaceuticals Holding Corp. | 86 | $1K |
| NRIXNurix Therapeutics, Inc. | 69 | $1K |
| ZVRAZEVRA THERAPEUTICS, INC. | 110 | $1K |
| BIOABioAge Labs, Inc. | 57 | $997 |
| ORICOric Pharmaceuticals, Inc. | 77 | $976 |
| IONSIONIS PHARMACEUTICALS INC | 13 | $976 |
| RZLTRezolute, Inc. | 317 | $967 |
| NGNENeurogene Inc. | 45 | $907 |
| SANASana Biotechnology, Inc. | 310 | $893 |
| CAPRCAPRICOR THERAPEUTICS, INC. | 28 | $851 |
| FATEFATE THERAPEUTICS INC | 685 | $822 |
| KRROKorro Bio, Inc. | 72 | $815 |
| SPRYARS Pharmaceuticals, Inc. | 99 | $795 |
| HUMAHumacyte Inc. | 1,090 | $661 |
| RXRXRECURSION PHARMACEUTICALS, INC. | 210 | $645 |
| OPKOPKO HEALTH, INC. | 552 | $629 |
| PVLAPALVELLA THERAPEUTICS, INC. | 5 | $623 |
| ALDXAldeyra Therapeutics, Inc. | 360 | $608 |
| MAZEMaze Therapeutics, Inc. | 20 | $597 |
| BCAXBicara Therapeutics Inc. | 30 | $597 |
| UPBUpstream Bio, Inc. | 61 | $549 |
| SVRASavara Inc | 100 | $546 |
| SLSSELLAS Life Sciences Group, Inc. | 127 | $537 |
| ALECAlector, Inc. | 240 | $516 |
| HURATuHURA Biosciences, Inc./NV | 234 | $419 |
| ZBIOZenas BioPharma, Inc. | 21 | $411 |
| PGENPRECIGEN, INC. | 101 | $391 |
| TECXTectonic Therapeutic, Inc. | 11 | $340 |
| CHRSCoherus Oncology, Inc. | 188 | $318 |
| AARDAardvark Therapeutics, Inc. | 77 | $290 |
| ATAIAtai Beckley N.V. | 77 | $273 |
| FLGTFulgent Genetics Inc. | 17 | $270 |
| VKTXViking Therapeutics, Inc. | 8 | $260 |
| RNAAtrium Therapeutics Inc. | 19 | $254 |
| TRDAEntrada Therapeutics, Inc. | 20 | $252 |
| RNACCartesian Therapeutics, Inc. | 40 | $246 |
| DSGNDesign Therapeutics, Inc. | 23 | $245 |
| ORGOOrganogenesis Holdings Inc. | 90 | $213 |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 249 | $199 |
| DNAGinkgo Bioworks Holdings Inc. | 32 | $196 |
| CATXPerspective Therapeutics, Inc. | 34 | $142 |
| VYGRVoyager Therapeutics, Inc. | 35 | $135 |
| FENCFENNEC PHARMACEUTICALS INC. | 19 | $117 |
| MLTXMoonLake Immunotherapeutics | 6 | $112 |
| JBIOJade Biosciences, Inc. | 7 | $98 |
| XOMAXOMA Royalty Corporation | 3 | $94 |
| PLSEPulse Biosciences Inc Common Stock (DE) | 4 | $86 |
| SMMTSummit Therapeutics Inc. | 3 | $57 |
| FDMT4D Molecular Therapeutics, Inc. | 6 | $56 |
| SIONSionna Therapeutics, Inc. | 1 | $40 |
| ALTAltimmune, Inc. | 13 | $40 |
| TVRDTvardi Therapeutics, Inc. | 12 | $38 |
| PLXProtalix BioTherapeutics, Inc. | 15 | $33 |
| MDWDMediWound Ltd. | 2 | $32 |
| DMACDiaMedica Therapeutics Inc. | 3 | $20 |
| CRDFCardiff Oncology, Inc. | 11 | $18 |
| CADLCandel Therapeutics, Inc. | 3 | $15 |
| ARTLARTELO BIOSCIENCES, INC. | 2 | $15 |
| NVCTNuvectis Pharma, Inc. | 1 | $8 |