| GILDGILEAD SCIENCES, INC. | 305,106 | $42.5M |
| AXSMAxsome Therapeutics, Inc. | 152,645 | $25.8M |
| REGNREGENERON PHARMACEUTICALS, INC. | 23,567 | $18.2M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 304,172 | $15.7M |
| ADMAADMA BIOLOGICS, INC. | 1,738,062 | $15.7M |
| VRDNViridian Therapeutics, Inc.\DE | 708,527 | $13.9M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 140,404 | $8.8M |
| CYTKCYTOKINETICS INC | 123,329 | $8.1M |
| BBIOBridgeBio Pharma, Inc. | 86,239 | $6.4M |
| ROIVRoivant Sciences Ltd. | 221,376 | $6.1M |
| EXELEXELIXIS, INC. | 137,441 | $5.9M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 100,456 | $5.7M |
| JAZZJazz Pharmaceuticals plc | 29,851 | $5.6M |
| MRNAModerna, Inc. | 81,427 | $4.1M |
| PCVXVaxcyte, Inc. | 67,854 | $3.9M |
| INCYIncyte Corp. | 40,821 | $3.8M |
| PTGXProtagonist Therapeutics, Inc | 31,799 | $3.4M |
| TEVATeva Pharmaceutical Industries Limited | 108,925 | $3.3M |
| COGTCogent Biosciences, Inc. | 78,621 | $3.0M |
| PTCTPTC THERAPEUTICS, INC. | 42,878 | $2.9M |
| NUVLNuvalent, Inc. | 27,397 | $2.8M |
| TERNTerns Pharmaceuticals, Inc. | 52,215 | $2.8M |
| TGTXTG THERAPEUTICS, INC. | 80,857 | $2.7M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 7,800 | $2.6M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 28,889 | $2.5M |
| FOLDAMICUS THERAPEUTICS, INC. | 165,913 | $2.4M |
| SRRKScholar Rock Holding Corp | 47,463 | $2.3M |
| LGNDLigand Pharmaceuticals Incorporated | 10,562 | $2.1M |
| APGEApogee Therapeutics, Inc. | 24,247 | $2.0M |
| INSMINSMED Inc | 12,290 | $2.0M |
| SYRESpyre Therapeutics, Inc. | 38,407 | $1.9M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 19,529 | $1.6M |
| ACADACADIA PHARMACEUTICALS INC | 68,672 | $1.5M |
| DNLIDenali Therapeutics Inc. | 77,558 | $1.5M |
| ARQTArcutis Biotherapeutics, Inc. | 60,975 | $1.4M |
| LQDALiquidia Corp | 36,685 | $1.4M |
| TVTXTravere Therapeutics, Inc. | 45,979 | $1.4M |
| TNGXTango Therapeutics, Inc. | 60,694 | $1.3M |
| BEAMBeam Therapeutics Inc. | 52,994 | $1.3M |
| IBRXImmunityBio, Inc. | 159,657 | $1.2M |
| ADPTAdaptive Biotechnologies Corp | 84,082 | $1.2M |
| CLDXCelldex Therapeutics, Inc. | 36,663 | $1.2M |
| AGIOAGIOS PHARMACEUTICALS, INC. | 32,858 | $1.1M |
| IMVTImmunovant, Inc. | 44,461 | $1.1M |
| ORKAOruka Therapeutics, Inc. | 21,363 | $1.0M |
| DFTXDefinium Therapeutics Inc. | 54,261 | $1.0M |
| RCUSArcus Biosciences, Inc. | 44,809 | $968K |
| IRONDisc Medicine, Inc. | 15,065 | $963K |
| DAWNDay One Biopharmaceuticals, Inc. | 44,101 | $946K |
| INVAInnoviva, Inc. | 39,907 | $930K |
| SLNOSOLENO THERAPEUTICS INC | 27,501 | $921K |
| VCELVericel Corp | 28,241 | $909K |
| NRIXNurix Therapeutics, Inc. | 55,948 | $867K |
| ELVNEnliven Therapeutics, Inc. | 22,094 | $866K |
| STOKStoke Therapeutics, Inc. | 26,106 | $850K |
| OCULOCULAR THERAPEUTIX, INC | 98,763 | $837K |
| ALMSALUMIS INC. | 37,558 | $827K |
| ANIPANI PHARMACEUTICALS INC | 10,521 | $809K |
| ARDXARDELYX, INC. | 133,005 | $797K |
| KODKodiak Sciences Inc. | 20,363 | $776K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 251,512 | $772K |
| NTLAIntellia Therapeutics, Inc. | 59,080 | $757K |
| ZYMEZymeworks Inc. | 29,653 | $743K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 23,195 | $705K |
| IONSIONIS PHARMACEUTICALS INC | 9,224 | $693K |
| HROWHARROW, INC. | 18,378 | $648K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 184,399 | $647K |
| OLMAOlema Pharmaceuticals, Inc. | 38,520 | $574K |
| ANABANAPTYSBIO, INC | 10,173 | $564K |
| NUVBNuvation Bio Inc. | 127,912 | $549K |
| BHVNBiohaven Ltd. | 64,787 | $548K |
| PVLAPALVELLA THERAPEUTICS, INC. | 4,260 | $531K |
| ORICOric Pharmaceuticals, Inc. | 35,689 | $452K |
| XERSXeris Biopharma Holdings, Inc. | 76,763 | $445K |
| CGEMCullinan Therapeutics, Inc. | 30,816 | $438K |
| KALVKalVista Pharmaceuticals, Inc. | 21,688 | $437K |
| MAZEMaze Therapeutics, Inc. | 14,542 | $434K |
| ANNXAnnexon, Inc. | 72,444 | $401K |
| SLSSELLAS Life Sciences Group, Inc. | 94,255 | $399K |
| SVRASavara Inc | 69,449 | $379K |
| GERNGERON CORP | 250,662 | $373K |
| BCAXBicara Therapeutics Inc. | 18,360 | $365K |
| ABUSArbutus Biopharma Corp | 81,069 | $365K |
| ARVNARVINAS, INC. | 33,035 | $350K |
| SIONSionna Therapeutics, Inc. | 8,565 | $343K |
| CMPXCompass Therapeutics, Inc. | 64,205 | $340K |
| PGENPRECIGEN, INC. | 83,112 | $322K |
| KURAKura Oncology, Inc. | 38,811 | $316K |
| BIOABioAge Labs, Inc. | 16,725 | $293K |
| SPRYARS Pharmaceuticals, Inc. | 34,338 | $276K |
| LBRXLB PHARMACEUTICALS INC | 11,104 | $274K |
| RVMDREVOLUTION MEDICINES, INC. | 2,788 | $271K |
| APLSApellis Pharmaceuticals, Inc. | 6,633 | $267K |
| ESPREsperion Therapeutics, Inc. | 96,652 | $265K |
| ZBIOZenas BioPharma, Inc. | 12,909 | $252K |
| JBIOJade Biosciences, Inc. | 17,935 | $252K |
| ZVRAZEVRA THERAPEUTICS, INC. | 26,275 | $245K |
| OPKOPKO HEALTH, INC. | 204,738 | $233K |
| FDMT4D Molecular Therapeutics, Inc. | 24,601 | $229K |
| TRDAEntrada Therapeutics, Inc. | 17,802 | $225K |
| ALTAltimmune, Inc. | 72,213 | $222K |
| PLSEPulse Biosciences Inc Common Stock (DE) | 9,794 | $211K |
| TECXTectonic Therapeutic, Inc. | 6,724 | $208K |
| FLGTFulgent Genetics Inc. | 12,579 | $200K |
| ABSIAbsci Corporation | 66,490 | $199K |
| MPLTMapLight Therapeutics, Inc. | 9,798 | $199K |
| SANASana Biotechnology, Inc. | 66,551 | $192K |
| SLDBSolid Biosciences Inc. | 26,483 | $191K |
| PRTAPROTHENA CORP PUBLIC LTD CO | 19,516 | $190K |
| AQSTAquestive Therapeutics, Inc. | 44,407 | $184K |
| KROSKeros Therapeutics, Inc. | 16,682 | $184K |
| XOMAXOMA Royalty Corporation | 5,677 | $178K |
| UPBUpstream Bio, Inc. | 19,380 | $174K |
| RGNXREGENXBIO Inc. | 20,030 | $168K |
| RCKTRocket Pharmaceuticals Inc. | 46,551 | $167K |
| DSGNDesign Therapeutics, Inc. | 15,249 | $162K |
| DNAGinkgo Bioworks Holdings Inc. | 22,948 | $141K |
| CATXPerspective Therapeutics, Inc. | 33,079 | $138K |
| SMMTSummit Therapeutics Inc. | 7,186 | $136K |
| RZLTRezolute, Inc. | 42,094 | $128K |
| LRMRLarimar Therapeutics, Inc. | 26,668 | $120K |
| NGNENeurogene Inc. | 5,932 | $120K |
| RNAAtrium Therapeutics Inc. | 8,845 | $118K |
| TNXPTonix Pharmaceuticals Holding Corp. | 8,590 | $118K |
| AVXLANAVEX LIFE SCIENCES CORP. | 35,430 | $109K |
| ABEOABEONA THERAPEUTICS INC. | 23,772 | $106K |
| PBYIPUMA BIOTECHNOLOGY, INC. | 15,842 | $101K |
| VYGRVoyager Therapeutics, Inc. | 26,113 | $101K |
| MDWDMediWound Ltd. | 5,908 | $95K |
| PLXProtalix BioTherapeutics, Inc. | 43,697 | $95K |
| LENZLENZ Therapeutics, Inc. | 9,787 | $90K |
| FENCFENNEC PHARMACEUTICALS INC. | 13,509 | $83K |
| DMACDiaMedica Therapeutics Inc. | 11,863 | $80K |
| CADLCandel Therapeutics, Inc. | 16,199 | $79K |
| ALECAlector, Inc. | 36,208 | $78K |
| VKTXViking Therapeutics, Inc. | 2,174 | $71K |
| CHRSCoherus Oncology, Inc. | 39,013 | $66K |
| SIGASIGA TECHNOLOGIES INC | 11,757 | $63K |
| HUMAHumacyte Inc. | 70,106 | $43K |
| ORGOOrganogenesis Holdings Inc. | 15,485 | $37K |
| OGNOrganon & Co. | 4,257 | $25K |
| SCLXSCILEX HOLDING CO | 1,090 | $7K |