| ALNYALNYLAM PHARMACEUTICALS, INC. | 1,099,318 | $363.7M |
| GILDGILEAD SCIENCES, INC. | 2,310,515 | $322.0M |
| INCYIncyte Corp. | 1,253,138 | $117.9M |
| RCUSArcus Biosciences, Inc. | 3,761,437 | $81.2M |
| PTGXProtagonist Therapeutics, Inc | 628,075 | $66.2M |
| ROIVRoivant Sciences Ltd. | 2,246,943 | $62.2M |
| COGTCogent Biosciences, Inc. | 1,600,168 | $61.6M |
| ARQTArcutis Biotherapeutics, Inc. | 2,431,778 | $57.3M |
| SRRKScholar Rock Holding Corp | 1,060,275 | $52.1M |
| ONCBeOne Medicines Ltd. | 172,643 | $51.3M |
| INSMINSMED Inc | 312,565 | $51.1M |
| TERNTerns Pharmaceuticals, Inc. | 927,600 | $48.9M |
| CYTKCYTOKINETICS INC | 656,608 | $43.3M |
| MANEVeradermics Incorporated | 654,601 | $41.3M |
| APLSApellis Pharmaceuticals, Inc. | 929,019 | $37.4M |
| RDYDR REDDYS LABORATORIES LTD | 2,664,306 | $36.9M |
| INVAInnoviva, Inc. | 1,504,411 | $35.1M |
| PTCTPTC THERAPEUTICS, INC. | 460,638 | $31.4M |
| RLMDRELMADA THERAPEUTICS, INC. | 4,481,606 | $31.2M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 341,929 | $28.7M |
| ALMSALUMIS INC. | 1,172,749 | $25.8M |
| BBIOBridgeBio Pharma, Inc. | 334,382 | $24.8M |
| SVRASavara Inc | 4,514,348 | $24.6M |
| AXSMAxsome Therapeutics, Inc. | 141,236 | $23.9M |
| HROWHARROW, INC. | 644,918 | $22.7M |
| DFTXDefinium Therapeutics Inc. | 1,200,825 | $22.7M |
| CMPSCOMPASS Pathways plc | 4,038,335 | $22.3M |
| RVMDREVOLUTION MEDICINES, INC. | 216,661 | $21.1M |
| CTMXCytomX Therapeutics, Inc. | 4,138,176 | $19.4M |
| ESPREsperion Therapeutics, Inc. | 7,075,083 | $19.4M |
| DNLIDenali Therapeutics Inc. | 991,268 | $19.0M |
| AGIOAGIOS PHARMACEUTICALS, INC. | 448,118 | $15.2M |
| IMMXImmix Biopharma, Inc. | 1,641,552 | $15.0M |
| CGEMCullinan Therapeutics, Inc. | 1,049,581 | $14.9M |
| KNSAKiniksa Pharmaceuticals International, plc | 305,371 | $14.7M |
| OCGNOcugen, Inc. | 8,052,350 | $14.6M |
| JBIOJade Biosciences, Inc. | 944,776 | $13.3M |
| EXELEXELIXIS, INC. | 300,013 | $12.9M |
| ALTAltimmune, Inc. | 4,017,901 | $12.4M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 179,573 | $11.3M |
| LQDALiquidia Corp | 289,439 | $10.9M |
| RCKTRocket Pharmaceuticals Inc. | 3,038,715 | $10.9M |
| IRDOpus Genetics, Inc. | 2,313,380 | $10.5M |
| NKTRNEKTAR THERAPEUTICS | 140,588 | $10.1M |
| ZBIOZenas BioPharma, Inc. | 501,928 | $9.8M |
| ARDXARDELYX, INC. | 1,600,857 | $9.6M |
| MAZEMaze Therapeutics, Inc. | 310,639 | $9.3M |
| SMMTSummit Therapeutics Inc. | 475,241 | $9.0M |
| RXRXRECURSION PHARMACEUTICALS, INC. | 2,876,928 | $8.8M |
| SLSSELLAS Life Sciences Group, Inc. | 2,037,162 | $8.6M |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 264,802 | $8.5M |
| ATAIAtai Beckley N.V. | 2,364,446 | $8.4M |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 2,355,612 | $8.3M |
| CNTXContext Therapeutics Inc. | 2,948,441 | $7.7M |
| ALXOALX ONCOLOGY HOLDINGS INC | 3,757,216 | $7.5M |
| FOLDAMICUS THERAPEUTICS, INC. | 518,008 | $7.5M |
| SLNOSOLENO THERAPEUTICS INC | 221,214 | $7.4M |
| IONSIONIS PHARMACEUTICALS INC | 95,954 | $7.2M |
| TECXTectonic Therapeutic, Inc. | 229,595 | $7.1M |
| DAWNDay One Biopharmaceuticals, Inc. | 328,638 | $7.0M |
| SYRESpyre Therapeutics, Inc. | 139,259 | $7.0M |
| MRNAModerna, Inc. | 133,815 | $6.8M |
| APGEApogee Therapeutics, Inc. | 80,201 | $6.8M |
| CNTACentessa Pharmaceuticals plc | 168,177 | $6.7M |
| VCELVericel Corp | 206,669 | $6.6M |
| OCULOCULAR THERAPEUTIX, INC | 740,803 | $6.3M |
| TENXTENAX THERAPEUTICS, INC. | 352,572 | $5.6M |
| OGNOrganon & Co. | 933,176 | $5.6M |
| STROSUTRO BIOPHARMA, INC. | 222,634 | $5.5M |
| IMCRImmunocore Holdings plc | 180,340 | $5.4M |
| TVTXTravere Therapeutics, Inc. | 178,536 | $5.3M |
| CLYMClimb Bio, Inc. | 773,123 | $5.3M |
| VRDNViridian Therapeutics, Inc.\DE | 269,587 | $5.3M |
| ZURAZura Bio Ltd | 852,340 | $5.1M |
| SGMTSagimet Biosciences Inc. | 966,253 | $5.0M |
| LCTXLineage Cell Therapeutics, Inc. | 3,065,033 | $4.8M |
| ANNXAnnexon, Inc. | 861,475 | $4.8M |
| ASMBASSEMBLY BIOSCIENCES, INC. | 163,400 | $4.5M |
| GERNGERON CORP | 2,960,047 | $4.4M |
| DMRADamora Therapeutics, Inc. | 169,818 | $4.4M |
| LRMRLarimar Therapeutics, Inc. | 933,464 | $4.2M |
| HRMYHarmony Biosciences Holdings, Inc. | 149,715 | $4.2M |
| IMVTImmunovant, Inc. | 165,300 | $4.1M |
| ZVRAZEVRA THERAPEUTICS, INC. | 439,952 | $4.1M |
| FBRXForte Biosciences, Inc. | 150,307 | $3.9M |
| ANABANAPTYSBIO, INC | 68,047 | $3.8M |
| LXRXLEXICON PHARMACEUTICALS, INC. | 2,376,304 | $3.7M |
| CBIOCRESCENT BIOPHARMA, INC. | 200,780 | $3.7M |
| ABSIAbsci Corporation | 1,219,052 | $3.7M |
| IVAInventiva S.A. | 654,211 | $3.6M |
| GALTGALECTIN THERAPEUTICS INC | 1,219,912 | $3.4M |
| FLNAFilana Therapeutics Inc. | 2,012,543 | $3.4M |
| BIOABioAge Labs, Inc. | 190,472 | $3.3M |
| GPCRStructure Therapeutics Inc. | 69,107 | $3.3M |
| CAPRCAPRICOR THERAPEUTICS, INC. | 109,531 | $3.3M |
| BEAMBeam Therapeutics Inc. | 139,241 | $3.3M |
| KALVKalVista Pharmaceuticals, Inc. | 162,908 | $3.3M |
| BHVNBiohaven Ltd. | 352,605 | $3.0M |
| LYELLyell Immunopharma, Inc. | 148,516 | $3.0M |
| VKTXViking Therapeutics, Inc. | 90,360 | $2.9M |
| ANVSAnnovis Bio, Inc. | 1,187,499 | $2.6M |
| JAZZJazz Pharmaceuticals plc | 12,376 | $2.3M |
| MISTMilestone Pharmaceuticals Inc. | 1,944,530 | $2.3M |
| AGENAGENUS INC | 688,203 | $2.3M |
| MLTXMoonLake Immunotherapeutics | 111,331 | $2.1M |
| OVIDOvid Therapeutics Inc. | 917,733 | $2.0M |
| QUREuniQure N.V. | 122,736 | $2.0M |
| ALGSAligos Therapeutics, Inc. | 267,135 | $2.0M |
| AVTXAvalo Therapeutics, Inc. | 129,136 | $1.9M |
| SANASana Biotechnology, Inc. | 664,457 | $1.9M |
| BMEABiomea Fusion, Inc. | 1,198,551 | $1.8M |
| PROKPROKIDNEY CORP. | 1,011,744 | $1.8M |
| BDTXBlack Diamond Therapeutics, Inc. | 836,266 | $1.8M |
| SABSSAB BIOTHERAPEUTICS, INC. | 463,925 | $1.8M |
| NTLAIntellia Therapeutics, Inc. | 137,425 | $1.8M |
| BCYCBICYCLE THERAPEUTICS PLC | 377,335 | $1.8M |
| ACADACADIA PHARMACEUTICALS INC | 76,187 | $1.7M |
| DSGNDesign Therapeutics, Inc. | 151,008 | $1.6M |
| IVVDInvivyd, Inc. | 1,226,165 | $1.6M |
| RNACCartesian Therapeutics, Inc. | 251,115 | $1.5M |
| LGNDLigand Pharmaceuticals Incorporated | 7,505 | $1.5M |
| LENZLENZ Therapeutics, Inc. | 160,264 | $1.5M |
| XFORX4 Pharmaceuticals, Inc | 336,834 | $1.4M |
| CRBPCorbus Pharmaceuticals Holdings, Inc. | 146,596 | $1.4M |
| ALECAlector, Inc. | 620,424 | $1.3M |
| AVXLANAVEX LIFE SCIENCES CORP. | 419,497 | $1.3M |
| GHRSGH Research PLC | 91,108 | $1.3M |
| ABCLAbCellera Biologics Inc. | 359,683 | $1.3M |
| PLRXPLIANT THERAPEUTICS, INC. | 995,973 | $1.3M |
| PRLDPrelude Therapeutics Inc | 358,906 | $1.2M |
| ADPTAdaptive Biotechnologies Corp | 86,347 | $1.2M |
| IMUXIMMUNIC, INC. | 952,966 | $1.1M |
| ABEOABEONA THERAPEUTICS INC. | 216,305 | $969K |
| ZNTLZentalis Pharmaceuticals, Inc. | 392,643 | $919K |
| SLNSilence Therapeutics Plc | 169,616 | $894K |
| ORMPORAMED PHARMACEUTICALS INC. | 259,611 | $883K |
| TGTXTG THERAPEUTICS, INC. | 25,693 | $854K |
| SPRYARS Pharmaceuticals, Inc. | 105,006 | $843K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 9,628 | $837K |
| ZYMEZymeworks Inc. | 32,223 | $807K |
| ARVNARVINAS, INC. | 75,163 | $797K |
| ELTXElicio Therapeutics, Inc. | 74,512 | $797K |
| ASRTAssertio Holdings, Inc. | 40,772 | $777K |
| ONCYONCOLYTICS BIOTECH INC | 859,831 | $731K |
| TRDAEntrada Therapeutics, Inc. | 53,764 | $679K |
| UPBUpstream Bio, Inc. | 66,770 | $601K |
| IBRXImmunityBio, Inc. | 77,025 | $591K |
| SRZNSurrozen Inc. | 18,930 | $551K |
| IFRXInflaRx N.V. | 554,364 | $493K |
| CNTNCanton Strategic Holdings, Inc. | 149,600 | $489K |
| CHRSCoherus Oncology, Inc. | 270,087 | $456K |
| RNAAtrium Therapeutics Inc. | 33,691 | $450K |
| ANIXAnixa Biosciences Inc | 173,179 | $447K |
| NUVBNuvation Bio Inc. | 103,546 | $444K |
| PRTAPROTHENA CORP PUBLIC LTD CO | 44,574 | $433K |
| GRCEGrace Therapeutics, Inc. | 91,416 | $423K |
| CCCCC4 Therapeutics, Inc. | 155,495 | $409K |
| GMABGenmab A/S | 15,000 | $402K |
| KLRSKalaris Therapeutics, Inc. | 67,879 | $392K |
| KRROKorro Bio, Inc. | 34,343 | $389K |
| LITSLite Strategy, Inc. | 333,508 | $387K |
| SPROSpero Therapeutics, Inc. | 157,072 | $368K |
| ACIUAC Immune SA | 131,458 | $362K |
| NUVLNuvalent, Inc. | 3,194 | $327K |
| NBTXNanobiotix S.A. | 9,239 | $285K |
| REGNREGENERON PHARMACEUTICALS, INC. | 353 | $273K |
| NVCTNuvectis Pharma, Inc. | 29,223 | $226K |
| PGENPRECIGEN, INC. | 56,963 | $220K |
| ALDXAldeyra Therapeutics, Inc. | 129,693 | $219K |
| PRQRProQR Therapeutics N.V. | 115,945 | $188K |
| TLSATiziana Life Sciences Ltd | 157,566 | $184K |
| MESOMesoblast Limited | 11,057 | $170K |
| RZLTRezolute, Inc. | 52,568 | $160K |
| FDMT4D Molecular Therapeutics, Inc. | 16,728 | $156K |
| OKUROnKure Therapeutics, Inc. | 36,444 | $151K |
| CLLSCellectis S.A. | 41,112 | $130K |
| AQSTAquestive Therapeutics, Inc. | 18,315 | $76K |
| SGMOQSANGAMO THERAPEUTICS, INC | 303,862 | $76K |
| ANTXAN2 Therapeutics, Inc. | 17,700 | $61K |
| BCABBioAtla, Inc. | 277,630 | $44K |
| JSPRJasper Therapeutics Inc. | 45,656 | $40K |
| EVOEvotec SE | 15,189 | $38K |
| MGXMetagenomi Therapeutics, Inc. | 27,521 | $37K |
| AUTLAutolus Therapeutics plc | 26,682 | $37K |
| HYFTMindWalk Holdings Corp. | 25,246 | $29K |
| DWTXDogwood Therapeutics, Inc. | 11,756 | $25K |
| INOINOVIO PHARMACEUTICALS, INC. | 13,187 | $23K |
| IOBTQIO Biotech, Inc. | 301,291 | $18K |