| BMRNBIOMARIN PHARMACEUTICAL INC | 974,776 | $55.1M |
| APLSApellis Pharmaceuticals, Inc. | 1,190,416 | $47.9M |
| REGNREGENERON PHARMACEUTICALS, INC. | 32,001 | $24.7M |
| IONSIONIS PHARMACEUTICALS INC | 295,100 | $22.2M |
| ARGXARGENX SE | 30,000 | $21.9M |
| IMCRImmunocore Holdings plc | 633,174 | $19.1M |
| TERNTerns Pharmaceuticals, Inc. | 360,878 | $19.0M |
| ABVXAbivax SA | 139,379 | $15.5M |
| DAWNDay One Biopharmaceuticals, Inc. | 670,000 | $14.4M |
| GILDGILEAD SCIENCES, INC. | 100,010 | $13.9M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 40,000 | $13.2M |
| ACADACADIA PHARMACEUTICALS INC | 445,506 | $9.9M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 109,238 | $9.2M |
| GMABGenmab A/S | 310,000 | $8.3M |
| COGTCogent Biosciences, Inc. | 207,574 | $8.0M |
| RCUSArcus Biosciences, Inc. | 356,535 | $7.7M |
| SLNOSOLENO THERAPEUTICS INC | 203,291 | $6.8M |
| DNLIDenali Therapeutics Inc. | 346,360 | $6.7M |
| FOLDAMICUS THERAPEUTICS, INC. | 364,740 | $5.3M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 90,821 | $4.7M |
| BCAXBicara Therapeutics Inc. | 233,703 | $4.6M |
| ALMSALUMIS INC. | 193,395 | $4.3M |
| SRRKScholar Rock Holding Corp | 83,450 | $4.1M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 64,143 | $4.0M |
| NUVLNuvalent, Inc. | 28,480 | $2.9M |
| CHRSCoherus Oncology, Inc. | 1,704,980 | $2.9M |
| CYTKCYTOKINETICS INC | 39,470 | $2.6M |
| QUREuniQure N.V. | 158,500 | $2.6M |
| AXSMAxsome Therapeutics, Inc. | 15,220 | $2.6M |
| AVTXAvalo Therapeutics, Inc. | 161,087 | $2.4M |
| GRFSGrifols S.A. | 287,874 | $2.3M |
| OLMAOlema Pharmaceuticals, Inc. | 154,770 | $2.3M |
| DMRADamora Therapeutics, Inc. | 76,338 | $2.0M |
| RVMDREVOLUTION MEDICINES, INC. | 20,060 | $2.0M |
| PCVXVaxcyte, Inc. | 30,970 | $1.8M |
| AGIOAGIOS PHARMACEUTICALS, INC. | 51,830 | $1.8M |
| RXRXRECURSION PHARMACEUTICALS, INC. | 535,730 | $1.6M |
| CBIOCRESCENT BIOPHARMA, INC. | 88,867 | $1.6M |
| SGMTSagimet Biosciences Inc. | 303,223 | $1.6M |
| ABUSArbutus Biopharma Corp | 350,000 | $1.6M |
| RGNXREGENXBIO Inc. | 180,000 | $1.5M |
| KNSAKiniksa Pharmaceuticals International, plc | 27,670 | $1.3M |
| LRMRLarimar Therapeutics, Inc. | 292,250 | $1.3M |
| BBOTBridgeBio Oncology Therapeutics, Inc. | 110,000 | $985K |
| AQSTAquestive Therapeutics, Inc. | 234,000 | $971K |
| IVAInventiva S.A. | 145,459 | $807K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 9,120 | $793K |
| NTLAIntellia Therapeutics, Inc. | 60,000 | $769K |
| NKTRNEKTAR THERAPEUTICS | 10,332 | $743K |
| MANEVeradermics Incorporated | 11,079 | $700K |
| TGTXTG THERAPEUTICS, INC. | 20,590 | $684K |
| ATAIAtai Beckley N.V. | 188,485 | $667K |
| VYGRVoyager Therapeutics, Inc. | 156,250 | $603K |
| IMMXImmix Biopharma, Inc. | 63,501 | $578K |
| ZURAZura Bio Ltd | 95,355 | $567K |
| FBRXForte Biosciences, Inc. | 19,083 | $494K |
| APGEApogee Therapeutics, Inc. | 5,720 | $481K |
| IMVTImmunovant, Inc. | 19,230 | $478K |
| ASMBASSEMBLY BIOSCIENCES, INC. | 16,799 | $466K |
| PTGXProtagonist Therapeutics, Inc | 3,760 | $396K |
| OCGNOcugen, Inc. | 211,603 | $383K |
| CTMXCytomX Therapeutics, Inc. | 80,663 | $379K |
| CLYMClimb Bio, Inc. | 54,460 | $373K |
| STROSUTRO BIOPHARMA, INC. | 14,768 | $368K |
| CCCCC4 Therapeutics, Inc. | 130,081 | $342K |
| NSRXNasus Pharma Ltd | 134,771 | $299K |
| RLMDRELMADA THERAPEUTICS, INC. | 42,141 | $293K |
| CADLCandel Therapeutics, Inc. | 59,210 | $290K |
| CRBPCorbus Pharmaceuticals Holdings, Inc. | 29,578 | $278K |
| ZNTLZentalis Pharmaceuticals, Inc. | 117,127 | $274K |
| PVLAPALVELLA THERAPEUTICS, INC. | 2,140 | $267K |
| SRZNSurrozen Inc. | 8,653 | $252K |
| PTCTPTC THERAPEUTICS, INC. | 3,670 | $250K |
| SIONSionna Therapeutics, Inc. | 6,180 | $248K |
| MAZEMaze Therapeutics, Inc. | 8,150 | $243K |
| LXRXLEXICON PHARMACEUTICALS, INC. | 152,616 | $238K |
| IMUXIMMUNIC, INC. | 213,017 | $236K |
| ELTXElicio Therapeutics, Inc. | 20,208 | $216K |
| CAMPCamp4 Therapeutics Corp | 48,511 | $214K |
| TNGXTango Therapeutics, Inc. | 10,160 | $213K |
| GALTGALECTIN THERAPEUTICS INC | 74,728 | $208K |
| XFORX4 Pharmaceuticals, Inc | 50,287 | $208K |
| WHWKWhitehawk Therapeutics, Inc. | 57,597 | $199K |
| TVTXTravere Therapeutics, Inc. | 6,520 | $194K |
| IVVDInvivyd, Inc. | 140,061 | $182K |
| ARMPArmata Pharmaceuticals, Inc. | 17,584 | $180K |
| LCTXLineage Cell Therapeutics, Inc. | 111,287 | $176K |
| ORMPORAMED PHARMACEUTICALS INC. | 51,670 | $176K |
| ORICOric Pharmaceuticals, Inc. | 12,390 | $157K |
| SVRASavara Inc | 26,500 | $145K |
| ANTXAN2 Therapeutics, Inc. | 34,605 | $118K |
| AGENAGENUS INC | 33,543 | $112K |
| PROKPROKIDNEY CORP. | 62,084 | $111K |
| NUVBNuvation Bio Inc. | 25,070 | $108K |
| OCULOCULAR THERAPEUTIX, INC | 12,540 | $106K |
| CATXPerspective Therapeutics, Inc. | 23,090 | $96K |
| SLDBSolid Biosciences Inc. | 12,650 | $91K |
| GERNGERON CORP | 60,800 | $91K |
| SABSSAB BIOTHERAPEUTICS, INC. | 16,100 | $62K |
| ESPREsperion Therapeutics, Inc. | 11,850 | $32K |
| SANASana Biotechnology, Inc. | 10,000 | $29K |