| GILDGILEAD SCIENCES, INC. | 157,523 | $22.0M |
| REGNREGENERON PHARMACEUTICALS, INC. | 21,361 | $16.5M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 27,266 | $9.0M |
| INSMINSMED Inc | 47,015 | $7.7M |
| IONSIONIS PHARMACEUTICALS INC | 77,315 | $5.8M |
| ARGXARGENX SE | 5,035 | $3.7M |
| MRNAModerna, Inc. | 70,085 | $3.6M |
| ROIVRoivant Sciences Ltd. | 127,007 | $3.5M |
| RVMDREVOLUTION MEDICINES, INC. | 35,167 | $3.4M |
| INCYIncyte Corp. | 35,317 | $3.3M |
| SMMTSummit Therapeutics Inc. | 137,596 | $2.6M |
| BBIOBridgeBio Pharma, Inc. | 34,403 | $2.6M |
| SNYSanofi | 43,433 | $2.1M |
| JAZZJazz Pharmaceuticals plc | 10,924 | $2.1M |
| EXELEXELIXIS, INC. | 46,087 | $2.0M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 34,129 | $1.9M |
| ONCBeOne Medicines Ltd. | 5,672 | $1.7M |
| PTGXProtagonist Therapeutics, Inc | 14,923 | $1.6M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 24,850 | $1.6M |
| AXSMAxsome Therapeutics, Inc. | 9,078 | $1.5M |
| PCVXVaxcyte, Inc. | 25,540 | $1.5M |
| CYTKCYTOKINETICS INC | 21,856 | $1.4M |
| ABVXAbivax SA | 12,903 | $1.4M |
| IBRXImmunityBio, Inc. | 182,447 | $1.4M |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 43,703 | $1.4M |
| NUVLNuvalent, Inc. | 12,987 | $1.3M |
| COGTCogent Biosciences, Inc. | 28,803 | $1.1M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 12,118 | $1.1M |
| PTCTPTC THERAPEUTICS, INC. | 14,689 | $1.0M |
| TERNTerns Pharmaceuticals, Inc. | 18,869 | $995K |
| IMVTImmunovant, Inc. | 37,718 | $937K |
| APLSApellis Pharmaceuticals, Inc. | 22,684 | $913K |
| SRRKScholar Rock Holding Corp | 18,102 | $890K |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 16,000 | $889K |
| CNTACentessa Pharmaceuticals plc | 21,225 | $843K |
| APGEApogee Therapeutics, Inc. | 9,731 | $819K |
| DNLIDenali Therapeutics Inc. | 40,643 | $780K |
| LGNDLigand Pharmaceuticals Incorporated | 3,539 | $707K |
| SYRESpyre Therapeutics, Inc. | 13,938 | $703K |
| ACADACADIA PHARMACEUTICALS INC | 30,256 | $673K |
| GPCRStructure Therapeutics Inc. | 13,824 | $666K |
| TVTXTravere Therapeutics, Inc. | 19,825 | $589K |
| IRONDisc Medicine, Inc. | 8,372 | $535K |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 10,175 | $526K |
| ARQTArcutis Biotherapeutics, Inc. | 22,011 | $519K |
| TNGXTango Therapeutics, Inc. | 23,900 | $500K |
| ALMSALUMIS INC. | 22,436 | $494K |
| STOKStoke Therapeutics, Inc. | 15,136 | $493K |
| BEAMBeam Therapeutics Inc. | 18,075 | $431K |
| NTLAIntellia Therapeutics, Inc. | 33,464 | $429K |
| ORKAOruka Therapeutics, Inc. | 8,591 | $421K |
| KODKodiak Sciences Inc. | 10,834 | $413K |
| ELVNEnliven Therapeutics, Inc. | 10,532 | $413K |
| ADPTAdaptive Biotechnologies Corp | 28,925 | $401K |
| DAWNDay One Biopharmaceuticals, Inc. | 18,331 | $393K |
| KNSAKiniksa Pharmaceuticals International, plc | 8,145 | $392K |
| DFTXDefinium Therapeutics Inc. | 20,192 | $382K |
| ADMAADMA BIOLOGICS, INC. | 42,263 | $381K |
| DSGNDesign Therapeutics, Inc. | 35,109 | $374K |
| MAZEMaze Therapeutics, Inc. | 11,995 | $358K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 10,398 | $352K |
| ANABANAPTYSBIO, INC | 6,164 | $342K |
| ZYMEZymeworks Inc. | 13,280 | $333K |
| OCULOCULAR THERAPEUTIX, INC | 38,631 | $327K |
| IMCRImmunocore Holdings plc | 10,783 | $325K |
| PHVSPharvaris N.V. | 11,367 | $321K |
| ANNXAnnexon, Inc. | 57,683 | $320K |
| SIONSionna Therapeutics, Inc. | 7,920 | $318K |
| GMABGenmab A/S | 11,424 | $307K |
| INVAInnoviva, Inc. | 13,145 | $306K |
| ANIPANI PHARMACEUTICALS INC | 3,978 | $306K |
| VCELVericel Corp | 9,008 | $290K |
| NKTRNEKTAR THERAPEUTICS | 4,000 | $288K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 92,624 | $284K |
| NRIXNurix Therapeutics, Inc. | 18,250 | $283K |
| ATAIAtai Beckley N.V. | 75,255 | $266K |
| ZBIOZenas BioPharma, Inc. | 13,526 | $264K |
| ARDXARDELYX, INC. | 43,521 | $261K |
| CTMXCytomX Therapeutics, Inc. | 55,068 | $259K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 73,106 | $257K |
| XERSXeris Biopharma Holdings, Inc. | 42,245 | $245K |
| PGENPRECIGEN, INC. | 62,789 | $243K |
| HROWHARROW, INC. | 6,573 | $232K |
| ORICOric Pharmaceuticals, Inc. | 17,809 | $226K |
| BCAXBicara Therapeutics Inc. | 11,244 | $224K |
| OLMAOlema Pharmaceuticals, Inc. | 14,225 | $212K |
| ALVOAlvotech | 58,612 | $201K |
| SVRASavara Inc | 36,107 | $197K |
| TECXTectonic Therapeutic, Inc. | 6,332 | $196K |
| GHRSGH Research PLC | 13,507 | $190K |
| ABCLAbCellera Biologics Inc. | 53,798 | $188K |
| QUREuniQure N.V. | 11,054 | $181K |
| KALVKalVista Pharmaceuticals, Inc. | 8,970 | $181K |
| GRFSGrifols S.A. | 21,649 | $174K |
| GERNGERON CORP | 113,281 | $169K |
| ARVNARVINAS, INC. | 14,950 | $158K |
| ABUSArbutus Biopharma Corp | 34,129 | $154K |
| CGEMCullinan Therapeutics, Inc. | 10,484 | $149K |
| MESOMesoblast Limited | 9,290 | $143K |
| SPRYARS Pharmaceuticals, Inc. | 17,541 | $141K |
| SANASana Biotechnology, Inc. | 47,269 | $136K |
| BIOABioAge Labs, Inc. | 7,707 | $135K |
| ZURAZura Bio Ltd | 21,600 | $129K |
| ABSIAbsci Corporation | 42,685 | $128K |
| KURAKura Oncology, Inc. | 15,442 | $126K |
| PVLAPALVELLA THERAPEUTICS, INC. | 1,000 | $125K |
| ESPREsperion Therapeutics, Inc. | 42,424 | $116K |
| SLDBSolid Biosciences Inc. | 13,826 | $100K |
| ZVRAZEVRA THERAPEUTICS, INC. | 9,990 | $93K |
| PRTAPROTHENA CORP PUBLIC LTD CO | 9,553 | $93K |
| CMPSCOMPASS Pathways plc | 16,735 | $93K |
| BHVNBiohaven Ltd. | 10,800 | $91K |
| IVVDInvivyd, Inc. | 69,178 | $90K |
| AQSTAquestive Therapeutics, Inc. | 21,650 | $90K |
| IVAInventiva S.A. | 16,000 | $89K |
| LRMRLarimar Therapeutics, Inc. | 19,270 | $87K |
| UPBUpstream Bio, Inc. | 9,590 | $86K |
| TRDAEntrada Therapeutics, Inc. | 6,794 | $86K |
| FDMT4D Molecular Therapeutics, Inc. | 9,052 | $84K |
| LYELLyell Immunopharma, Inc. | 3,770 | $76K |
| RGNXREGENXBIO Inc. | 8,983 | $75K |
| SRZNSurrozen Inc. | 2,500 | $73K |
| CAMPCamp4 Therapeutics Corp | 16,000 | $71K |
| RCKTRocket Pharmaceuticals Inc. | 19,266 | $69K |
| ALTAltimmune, Inc. | 22,223 | $68K |
| SIGASIGA TECHNOLOGIES INC | 12,708 | $68K |
| CADLCandel Therapeutics, Inc. | 12,998 | $64K |
| KROSKeros Therapeutics, Inc. | 5,406 | $60K |
| PBYIPUMA BIOTECHNOLOGY, INC. | 9,028 | $58K |
| NGNENeurogene Inc. | 2,749 | $55K |
| LENZLENZ Therapeutics, Inc. | 5,553 | $51K |
| AVXLANAVEX LIFE SCIENCES CORP. | 16,445 | $50K |
| AUTLAutolus Therapeutics plc | 35,597 | $49K |
| ACIUAC Immune SA | 17,852 | $49K |
| NBPNovaBridge Biosciences | 19,919 | $49K |
| CCCCC4 Therapeutics, Inc. | 17,316 | $46K |
| CHRSCoherus Oncology, Inc. | 26,525 | $45K |
| SLNSilence Therapeutics Plc | 8,335 | $44K |
| VYGRVoyager Therapeutics, Inc. | 10,458 | $40K |
| BCYCBICYCLE THERAPEUTICS PLC | 8,222 | $38K |
| DMACDiaMedica Therapeutics Inc. | 5,000 | $34K |
| PRQRProQR Therapeutics N.V. | 20,000 | $32K |
| SGMTSagimet Biosciences Inc. | 5,501 | $29K |
| MENSJyong Biotech Ltd. | 13,173 | $28K |
| BDTXBlack Diamond Therapeutics, Inc. | 10,111 | $22K |
| HUMAHumacyte Inc. | 34,249 | $21K |
| AARDAardvark Therapeutics, Inc. | 3,864 | $15K |