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| UNHUnitedHealth Group Incorporated Common Stock (DE) | 11,713,684 | $3.17B |
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| ABTABBOTT LABORATORIES | 19,279,608 | $1.98B |
| BMYBRISTOL MYERS SQUIBB CO | 32,586,981 | $1.98B |
| AMGNAMGEN INC | 5,121,028 | $1.80B |
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| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 2,206,152 | $121.8M |
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| TEVATeva Pharmaceutical Industries Limited | 3,958,814 | $119.2M |
| UTHRUNITED THERAPEUTICS Corp | 199,426 | $118.3M |
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| FDMT4D Molecular Therapeutics, Inc. | 974,173 | $9.1M |
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| SANASana Biotechnology, Inc. | 2,946,861 | $8.5M |
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| ABUSArbutus Biopharma Corp | 1,683,628 | $7.6M |
| TSHATaysha Gene Therapies, Inc. | 1,677,046 | $7.5M |
| CGEMCullinan Therapeutics, Inc. | 516,724 | $7.3M |
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| BCAXBicara Therapeutics Inc. | 327,989 | $6.5M |
| GMABGenmab A/S | 241,520 | $6.5M |
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| GLUEMonte Rosa Therapeutics, Inc. | 387,542 | $6.4M |
| IMCRImmunocore Holdings plc | 206,866 | $6.2M |
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| TAKTakeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock) | 319,969 | $5.9M |
| MAZEMaze Therapeutics, Inc. | 195,084 | $5.8M |
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| LENZLENZ Therapeutics, Inc. | 547,534 | $5.0M |
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| CMPXCompass Therapeutics, Inc. | 865,613 | $4.6M |
| CORTCORCEPT THERAPEUTICS INC | 111,736 | $4.5M |
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| XNCRXencor Inc | 366,093 | $4.4M |
| PAHCPHIBRO ANIMAL HEALTH CORP | 78,957 | $4.4M |
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| PCRXPacira BioSciences, Inc. | 188,437 | $4.3M |
| NKTRNEKTAR THERAPEUTICS | 58,958 | $4.2M |
| MANEVeradermics Incorporated | 65,675 | $4.1M |
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| RIGLRIGEL PHARMACEUTICALS INC | 144,131 | $3.9M |
| ARRYARRAY BIOPHARMA INC | 535,102 | $3.9M |
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| OCULOCULAR THERAPEUTIX, INC | 397,092 | $3.4M |
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| LCTXLineage Cell Therapeutics, Inc. | 419,355 | $663K |
| TKNOAlpha Teknova, Inc. | 228,286 | $660K |
| CLOVClover Health Investments Corp. | 371,114 | $653K |
| OVIDOvid Therapeutics Inc. | 290,432 | $645K |
| EOLSEvolus, Inc. | 155,248 | $638K |
| SEPNSepterna, Inc. | 25,973 | $624K |
| XFORX4 Pharmaceuticals, Inc | 150,676 | $622K |
| GLPGGalapagos NV | 20,725 | $622K |
| ZVRAZEVRA THERAPEUTICS, INC. | 64,837 | $604K |
| BLTEBELITE BIO, INC | 3,778 | $602K |
| CLPTClearPoint Neuro Inc. | 66,075 | $601K |
| KROSKeros Therapeutics, Inc. | 53,654 | $592K |
| ANROAlto Neuroscience, Inc. | 25,677 | $577K |
| AVIRAtea Pharmaceuticals, Inc. | 105,640 | $568K |
| FBRXForte Biosciences, Inc. | 21,606 | $560K |
| IBIOiBio, Inc. | 290,413 | $552K |
| CHRSCoherus Oncology, Inc. | 324,133 | $548K |
| JBIOJade Biosciences, Inc. | 38,598 | $542K |
| IKTInhibikase Therapeutics, Inc. | 322,704 | $542K |
| NUSNu Skin Enterprises Inc. | 74,405 | $542K |
| ANIKAnika Therapeutics Inc. | 37,177 | $539K |
| CBIOCRESCENT BIOPHARMA, INC. | 29,277 | $538K |
| VMDViemed Healthcare Inc. | 58,216 | $536K |
| ORMPORAMED PHARMACEUTICALS INC. | 146,152 | $497K |
| TRDAEntrada Therapeutics, Inc. | 39,212 | $495K |
| KYTXKyverna Therapeutics, Inc. | 55,728 | $481K |
| ASRTAssertio Holdings, Inc. | 25,033 | $477K |
| BNRBurning Rock Biotech Limited | 29,164 | $470K |
| STROSUTRO BIOPHARMA, INC. | 18,873 | $470K |
| SGMOSANGAMO THERAPEUTICS, INC | 1,838,390 | $452K |
| PLRXPLIANT THERAPEUTICS, INC. | 352,708 | $444K |
| PHVSPharvaris N.V. | 15,645 | $442K |
| SNWVSANUWAVE Health Inc. | 25,503 | $441K |
| RGCRegencell Bioscience Holdings Ltd | 17,172 | $437K |
| UPBUpstream Bio, Inc. | 48,460 | $436K |
| INNVINNOVUS PHARMACEUTICALS, INC. | 53,307 | $428K |
| GENBGenerate Biomedicines Inc. | 34,196 | $427K |
| VYGRVoyager Therapeutics, Inc. | 107,431 | $415K |
| LBRXLB PHARMACEUTICALS INC | 16,618 | $410K |
| DMRADamora Therapeutics, Inc. | 15,647 | $405K |
| AGENAGENUS INC | 118,782 | $397K |
| NATRNATURES SUNSHINE PRODUCTS INC | 16,401 | $393K |
| MPLTMapLight Therapeutics, Inc. | 18,869 | $384K |
| IMMXImmix Biopharma, Inc. | 41,131 | $375K |
| ALDXAldeyra Therapeutics, Inc. | 215,332 | $364K |
| CLYMClimb Bio, Inc. | 52,921 | $363K |
| ALTSALT5 Sigma Corp | 321,750 | $357K |
| TECXTectonic Therapeutic, Inc. | 11,466 | $354K |
| XOMAXOMA Royalty Corporation | 11,018 | $346K |
| PALIPALISADE BIO, INC. | 197,074 | $345K |
| ENTAENANTA PHARMACEUTICALS INC | 26,593 | $336K |
| LONALeonaBio, Inc. | 32,566 | $335K |
| EDITEditas Medicine, Inc. | 134,866 | $333K |
| IPSCCentury Therapeutics, Inc. | 145,099 | $328K |
| NPCENeuropace Inc. | 24,698 | $325K |
| IRDOpus Genetics, Inc. | 67,015 | $305K |
| ASMBASSEMBLY BIOSCIENCES, INC. | 10,902 | $303K |
| CNTXContext Therapeutics Inc. | 114,888 | $301K |
| PRQRProQR Therapeutics N.V. | 185,110 | $300K |
| ACRSAclaris Therapeutics, Inc. | 79,539 | $298K |
| PMVPPMV Pharmaceuticals, Inc. | 240,531 | $298K |
| UTMDUtah Medical Products Inc. | 4,773 | $296K |
| DRTSAlpha Tau Medical Ltd. | 41,392 | $293K |
| CRONCronos Group Inc. | 115,817 | $291K |
| DMACDiaMedica Therapeutics Inc. | 42,768 | $290K |
| FHTXFoghorn Therapeutics Inc. | 60,100 | $287K |
| FRMMFORUM MARKETS Inc | 94,358 | $273K |
| PBYIPUMA BIOTECHNOLOGY, INC. | 40,364 | $258K |
| JSPRJasper Therapeutics Inc. | 293,259 | $257K |
| IMTXImmatics N.V. | 25,394 | $250K |
| DSGNDesign Therapeutics, Inc. | 23,264 | $248K |
| BDTXBlack Diamond Therapeutics, Inc. | 114,143 | $243K |
| NERVMinerva Neurosciences, Inc. | 39,970 | $241K |
| HUMAHumacyte Inc. | 396,113 | $240K |
| ATYRaTYR PHARMA INC | 303,559 | $237K |
| CADLCandel Therapeutics, Inc. | 47,402 | $232K |
| RCELAvita Medical Inc. | 62,128 | $230K |
| SGMTSagimet Biosciences Inc. | 43,858 | $229K |
| FATEFATE THERAPEUTICS INC | 188,564 | $226K |
| OBIOOrchestra BioMed Holdings Inc. | 52,761 | $224K |
| ARCTArcturus Therapeutics Holdings Inc. | 28,751 | $222K |
| HOWLWerewolf Therapeutics, Inc. | 264,583 | $220K |
| NGNENeurogene Inc. | 10,864 | $219K |
| SABSSAB BIOTHERAPEUTICS, INC. | 55,697 | $213K |
| LRMRLarimar Therapeutics, Inc. | 47,359 | $213K |
| ACHVACHIEVE LIFE SCIENCES, INC. | 70,684 | $208K |
| SNDLSNDL Inc. | 155,251 | $205K |
| PLYXPolaryx Therapeutics Inc. | 25,881 | $196K |
| UNCYUnicycive Therapeutics, Inc. | 29,530 | $194K |
| PRLDPrelude Therapeutics Inc | 56,525 | $193K |
| OABIOmniAb Inc. | 121,656 | $191K |
| HCMHUTCHMED (China) Limited | 12,489 | $187K |
| BNTCBenitec Biopharma Inc. | 17,376 | $185K |
| MBOTMicrobot Medical Inc. | 75,799 | $183K |
| WHWKWhitehawk Therapeutics, Inc. | 52,861 | $182K |
| CMPSCOMPASS Pathways plc | 32,332 | $179K |
| KMDAKAMADA LTD | 21,104 | $176K |
| PLXProtalix BioTherapeutics, Inc. | 79,079 | $172K |
| KRMDKORU Medical Systems Inc. Common Stock (DE) | 37,971 | $164K |
| ELTXElicio Therapeutics, Inc. | 15,333 | $164K |
| FENCFENNEC PHARMACEUTICALS INC. | 26,405 | $162K |
| LFCRLIFECORE BIOMEDICAL, INC. DE | 43,298 | $161K |
| SLNSilence Therapeutics Plc | 29,773 | $157K |
| DERMJourney Medical Corp | 32,206 | $151K |
| DTILPRECISION BIOSCIENCES INC | 27,416 | $151K |
| GALTGALECTIN THERAPEUTICS INC | 53,862 | $150K |
| STIMNeuronetics Inc. | 98,095 | $142K |
| HURATuHURA Biosciences, Inc./NV | 78,142 | $140K |
| CAMPCamp4 Therapeutics Corp | 31,196 | $138K |
| CVMCEL SCI CORP | 40,997 | $132K |
| CRBPCorbus Pharmaceuticals Holdings, Inc. | 13,960 | $131K |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 160,979 | $129K |
| CSBRCHAMPIONS ONCOLOGY, INC. | 21,833 | $126K |
| ENLVEnlivex Ltd. | 130,401 | $121K |
| ARMPArmata Pharmaceuticals, Inc. | 11,714 | $120K |
| NVCTNuvectis Pharma, Inc. | 14,847 | $115K |
| NKTXNkarta, Inc. | 53,442 | $113K |
| KPTIKaryopharm Therapeutics Inc. | 19,472 | $108K |
| LUCDLucid Diagnostics Inc. | 88,527 | $102K |
| LFVNLifevantage Corp | 23,445 | $101K |
| MDXHMDxHealth SA | 43,492 | $100K |
| TLXTelix Pharmaceuticals Limited | 10,031 | $96K |
| SKINThe Beauty Health Company | 106,242 | $95K |
| PEPGPepGen Inc. | 53,316 | $94K |
| MXCTMaxCyte Inc. | 127,258 | $89K |
| CRDFCardiff Oncology, Inc. | 51,119 | $83K |
| BTMDbiote Corp. | 58,846 | $79K |
| GYREGYRE THERAPEUTICS, INC. | 10,538 | $73K |
| TCRXTScan Therapeutics, Inc. | 57,529 | $58K |
| GUTSFractyl Health Inc. | 124,989 | $57K |
| INOINOVIO PHARMACEUTICALS, INC. | 32,677 | $57K |
| LSTALISATA THERAPEUTICS, INC. | 10,353 | $52K |
| ACIUAC Immune SA | 17,437 | $48K |
| MNOVMEDICINOVA INC | 34,359 | $47K |
| AARDAardvark Therapeutics, Inc. | 11,486 | $43K |
| CNTBConnect Biopharma Holdings Ltd | 15,673 | $41K |
| ACTUACTUATE THERAPEUTICS, INC. | 11,034 | $30K |
| INMBInmune Bio, Inc. | 25,502 | $29K |
| PYXSPyxis Oncology, Inc. | 16,807 | $25K |
| ACRVAcrivon Therapeutics, Inc. | 16,513 | $23K |
| TNYATenaya Therapeutics, Inc. | 29,083 | $20K |
| ADGMAdagio Medical Holdings Inc | 12,857 | $15K |
| IMMPImmutep Limited | 10,000 | $4K |