| GILDGILEAD SCIENCES, INC. | 55,879 | $7.8M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 46,558 | $2.4M |
| REGNREGENERON PHARMACEUTICALS, INC. | 2,991 | $2.3M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 13,296 | $734K |
| INCYIncyte Corp. | 4,834 | $455K |
| SNYSanofi | 8,990 | $433K |
| EXELEXELIXIS, INC. | 10,084 | $433K |
| BMRNBIOMARIN PHARMACEUTICAL INC | 7,598 | $429K |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 1,283 | $425K |
| AXSMAxsome Therapeutics, Inc. | 1,482 | $250K |
| RDYDR REDDYS LABORATORIES LTD | 16,116 | $223K |
| MRNAModerna, Inc. | 4,368 | $222K |
| ROIVRoivant Sciences Ltd. | 6,831 | $189K |
| INSMINSMED Inc | 726 | $119K |
| JAZZJazz Pharmaceuticals plc | 448 | $85K |
| PCVXVaxcyte, Inc. | 1,437 | $84K |
| ARGXARGENX SE | 113 | $82K |
| ZURAZura Bio Ltd | 13,316 | $79K |
| FOLDAMICUS THERAPEUTICS, INC. | 5,206 | $75K |
| VKTXViking Therapeutics, Inc. | 2,280 | $74K |
| RVMDREVOLUTION MEDICINES, INC. | 684 | $67K |
| IMMXImmix Biopharma, Inc. | 7,245 | $66K |
| GRFSGrifols S.A. | 8,175 | $66K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 2,067 | $63K |
| BEAMBeam Therapeutics Inc. | 2,536 | $60K |
| DMACDiaMedica Therapeutics Inc. | 8,189 | $55K |
| ABCLAbCellera Biologics Inc. | 15,401 | $54K |
| NKTRNEKTAR THERAPEUTICS | 681 | $49K |
| ADMAADMA BIOLOGICS, INC. | 5,385 | $49K |
| PTCTPTC THERAPEUTICS, INC. | 678 | $46K |
| NTLAIntellia Therapeutics, Inc. | 3,592 | $46K |
| APLSApellis Pharmaceuticals, Inc. | 1,143 | $46K |
| TERNTerns Pharmaceuticals, Inc. | 781 | $41K |
| LGNDLigand Pharmaceuticals Incorporated | 204 | $41K |
| IONSIONIS PHARMACEUTICALS INC | 522 | $39K |
| TGTXTG THERAPEUTICS, INC. | 1,162 | $39K |
| IRONDisc Medicine, Inc. | 599 | $38K |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 610 | $38K |
| TEVATeva Pharmaceutical Industries Limited | 1,247 | $38K |
| OGNOrganon & Co. | 5,963 | $36K |
| KURAKura Oncology, Inc. | 4,157 | $34K |
| PTGXProtagonist Therapeutics, Inc | 313 | $33K |
| CYTKCYTOKINETICS INC | 482 | $32K |
| ARDXARDELYX, INC. | 5,240 | $31K |
| RCKTRocket Pharmaceuticals Inc. | 8,700 | $31K |
| INVAInnoviva, Inc. | 1,300 | $30K |
| GMABGenmab A/S | 1,119 | $30K |
| BHVNBiohaven Ltd. | 3,541 | $30K |
| NUVLNuvalent, Inc. | 287 | $29K |
| SRRKScholar Rock Holding Corp | 545 | $27K |
| TVTXTravere Therapeutics, Inc. | 806 | $24K |
| BBIOBridgeBio Pharma, Inc. | 317 | $24K |
| ADPTAdaptive Biotechnologies Corp | 1,688 | $23K |
| ONCBeOne Medicines Ltd. | 73 | $22K |
| DAWNDay One Biopharmaceuticals, Inc. | 1,002 | $21K |
| ABEOABEONA THERAPEUTICS INC. | 4,500 | $20K |
| ARQTArcutis Biotherapeutics, Inc. | 829 | $20K |
| VERUVERU INC. | 7,817 | $17K |
| CGEMCullinan Therapeutics, Inc. | 1,146 | $16K |
| KNSAKiniksa Pharmaceuticals International, plc | 319 | $15K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 4,816 | $15K |
| KODKodiak Sciences Inc. | 385 | $15K |
| RLMDRELMADA THERAPEUTICS, INC. | 2,000 | $14K |
| XERSXeris Biopharma Holdings, Inc. | 2,315 | $13K |
| OPKOPKO HEALTH, INC. | 11,661 | $13K |
| NUVBNuvation Bio Inc. | 3,094 | $13K |
| IMVTImmunovant, Inc. | 503 | $12K |
| MLTXMoonLake Immunotherapeutics | 669 | $12K |
| COGTCogent Biosciences, Inc. | 320 | $12K |
| ARVNARVINAS, INC. | 1,131 | $12K |
| TNGXTango Therapeutics, Inc. | 563 | $12K |
| KALVKalVista Pharmaceuticals, Inc. | 573 | $12K |
| VCELVericel Corp | 350 | $11K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 3,160 | $11K |
| ALMSALUMIS INC. | 503 | $11K |
| IBRXImmunityBio, Inc. | 1,376 | $11K |
| RGNXREGENXBIO Inc. | 1,226 | $10K |
| ORKAOruka Therapeutics, Inc. | 205 | $10K |
| ABUSArbutus Biopharma Corp | 2,060 | $9K |
| ESPREsperion Therapeutics, Inc. | 3,366 | $9K |
| PRTAPROTHENA CORP PUBLIC LTD CO | 946 | $9K |
| ACADACADIA PHARMACEUTICALS INC | 413 | $9K |
| ANABANAPTYSBIO, INC | 154 | $9K |
| LQDALiquidia Corp | 224 | $8K |
| OCULOCULAR THERAPEUTIX, INC | 984 | $8K |
| BIVIBIOVIE INC. | 5,600 | $8K |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 9,523 | $8K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 83 | $7K |
| ONCYONCOLYTICS BIOTECH INC | 8,452 | $7K |
| LRMRLarimar Therapeutics, Inc. | 1,522 | $7K |
| SPRYARS Pharmaceuticals, Inc. | 825 | $7K |
| SIGASIGA TECHNOLOGIES INC | 1,134 | $6K |
| AVXLANAVEX LIFE SCIENCES CORP. | 1,965 | $6K |
| SYRESpyre Therapeutics, Inc. | 117 | $6K |
| ANNXAnnexon, Inc. | 1,061 | $6K |
| OLMAOlema Pharmaceuticals, Inc. | 365 | $5K |
| DNLIDenali Therapeutics Inc. | 280 | $5K |
| ORGOOrganogenesis Holdings Inc. | 2,176 | $5K |
| SMMTSummit Therapeutics Inc. | 270 | $5K |
| MESOMesoblast Limited | 330 | $5K |
| GYREGYRE THERAPEUTICS, INC. | 721 | $5K |
| FDMT4D Molecular Therapeutics, Inc. | 509 | $5K |
| ABSIAbsci Corporation | 1,564 | $5K |
| ACOGAlpha Cognition Inc. | 750 | $4K |
| GERNGERON CORP | 2,721 | $4K |
| FATEFATE THERAPEUTICS INC | 3,252 | $4K |
| TRDAEntrada Therapeutics, Inc. | 309 | $4K |
| RZLTRezolute, Inc. | 1,184 | $4K |
| ALDXAldeyra Therapeutics, Inc. | 2,085 | $4K |
| SANASana Biotechnology, Inc. | 1,222 | $4K |
| HUMAHumacyte Inc. | 5,685 | $3K |
| KRROKorro Bio, Inc. | 291 | $3K |
| HYFTMindWalk Holdings Corp. | 2,850 | $3K |
| KROSKeros Therapeutics, Inc. | 287 | $3K |
| TNXPTonix Pharmaceuticals Holding Corp. | 230 | $3K |
| MANEVeradermics Incorporated | 50 | $3K |
| CMPXCompass Therapeutics, Inc. | 592 | $3K |
| SLDBSolid Biosciences Inc. | 418 | $3K |
| CBIOCRESCENT BIOPHARMA, INC. | 161 | $3K |
| AQSTAquestive Therapeutics, Inc. | 705 | $3K |
| FLGTFulgent Genetics Inc. | 182 | $3K |
| DNAGinkgo Bioworks Holdings Inc. | 461 | $3K |
| ZYMEZymeworks Inc. | 109 | $3K |
| CLDXCelldex Therapeutics, Inc. | 86 | $3K |
| IMCRImmunocore Holdings plc | 86 | $3K |
| DFTXDefinium Therapeutics Inc. | 127 | $2K |
| UPBUpstream Bio, Inc. | 263 | $2K |
| LENZLENZ Therapeutics, Inc. | 256 | $2K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 68 | $2K |
| NRIXNurix Therapeutics, Inc. | 145 | $2K |
| PBYIPUMA BIOTECHNOLOGY, INC. | 341 | $2K |
| PVLAPALVELLA THERAPEUTICS, INC. | 17 | $2K |
| TECXTectonic Therapeutic, Inc. | 65 | $2K |
| DNTHDianthus Therapeutics, Inc. /DE/ | 22 | $2K |
| ORICOric Pharmaceuticals, Inc. | 140 | $2K |
| HURATuHURA Biosciences, Inc./NV | 985 | $2K |
| HROWHARROW, INC. | 50 | $2K |
| RCUSArcus Biosciences, Inc. | 80 | $2K |
| CLLSCellectis S.A. | 500 | $2K |
| ELVNEnliven Therapeutics, Inc. | 39 | $2K |
| QUREuniQure N.V. | 91 | $1K |
| BCAXBicara Therapeutics Inc. | 74 | $1K |
| CHRSCoherus Oncology, Inc. | 846 | $1K |
| JBIOJade Biosciences, Inc. | 100 | $1K |
| DSGNDesign Therapeutics, Inc. | 130 | $1K |
| ALECAlector, Inc. | 627 | $1K |
| APGEApogee Therapeutics, Inc. | 16 | $1K |
| XFORX4 Pharmaceuticals, Inc | 310 | $1K |
| ABVXAbivax SA | 11 | $1K |
| SIONSionna Therapeutics, Inc. | 29 | $1K |
| VYGRVoyager Therapeutics, Inc. | 297 | $1K |
| SVRASavara Inc | 205 | $1K |
| IVVDInvivyd, Inc. | 793 | $1K |
| PLSEPulse Biosciences Inc Common Stock (DE) | 44 | $950 |
| PGENPRECIGEN, INC. | 231 | $894 |
| SLNOSOLENO THERAPEUTICS INC | 26 | $871 |
| LYELLyell Immunopharma, Inc. | 43 | $863 |
| ASMBASSEMBLY BIOSCIENCES, INC. | 29 | $805 |
| AARDAardvark Therapeutics, Inc. | 207 | $781 |
| RNACCartesian Therapeutics, Inc. | 126 | $775 |
| OCGNOcugen, Inc. | 406 | $735 |
| RNAAtrium Therapeutics Inc. | 54 | $722 |
| MGXMetagenomi Therapeutics, Inc. | 500 | $670 |
| VRDNViridian Therapeutics, Inc.\DE | 34 | $666 |
| TVRDTvardi Therapeutics, Inc. | 206 | $656 |
| CADLCandel Therapeutics, Inc. | 132 | $647 |
| NGNENeurogene Inc. | 30 | $605 |
| ZBIOZenas BioPharma, Inc. | 26 | $509 |
| ATAIAtai Beckley N.V. | 136 | $482 |
| GPCRStructure Therapeutics Inc. | 9 | $434 |
| BCTXBriaCell Therapeutics Corp. | 100 | $419 |
| MAZEMaze Therapeutics, Inc. | 14 | $418 |
| STOKStoke Therapeutics, Inc. | 12 | $391 |
| KZRKezar Life Sciences, Inc. | 50 | $371 |
| ASRTAssertio Holdings, Inc. | 18 | $344 |
| CLYMClimb Bio, Inc. | 45 | $309 |
| VIVSVivoSim Labs, INC. | 208 | $298 |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 9 | $289 |
| ZVRAZEVRA THERAPEUTICS, INC. | 30 | $280 |
| SGMOQSANGAMO THERAPEUTICS, INC | 1,000 | $247 |
| ATOSATOSSA THERAPEUTICS, INC. | 46 | $242 |
| ALTAltimmune, Inc. | 70 | $216 |
| AGENAGENUS INC | 58 | $194 |
| BIOABioAge Labs, Inc. | 11 | $193 |
| CTMXCytomX Therapeutics, Inc. | 37 | $174 |
| ANIPANI PHARMACEUTICALS INC | 2 | $154 |
| CATXPerspective Therapeutics, Inc. | 35 | $146 |
| FENCFENNEC PHARMACEUTICALS INC. | 23 | $142 |
| LGVNLongeveron Inc. | 130 | $136 |
| MPLTMapLight Therapeutics, Inc. | 6 | $122 |
| SLSSELLAS Life Sciences Group, Inc. | 26 | $110 |
| CYPHCYPHERPUNK TECHNOLOGIES INC. | 135 | $108 |
| XOMAXOMA Royalty Corporation | 3 | $95 |
| INOINOVIO PHARMACEUTICALS, INC. | 47 | $82 |
| AUTLAutolus Therapeutics plc | 50 | $69 |
| PLXProtalix BioTherapeutics, Inc. | 26 | $57 |
| TAOXTAO Synergies Inc. | 10 | $57 |
| RLYBRallybio Corp | 6 | $54 |
| SCLXSCILEX HOLDING CO | 6 | $40 |
| LCTXLineage Cell Therapeutics, Inc. | 22 | $35 |
| CRDFCardiff Oncology, Inc. | 20 | $33 |
| LBRXLB PHARMACEUTICALS INC | 1 | $25 |
| IRDOpus Genetics, Inc. | 5 | $23 |
| FBLGFibroBiologics, Inc. | 13 | $18 |
| MDWDMediWound Ltd. | 1 | $17 |
| TENXTENAX THERAPEUTICS, INC. | 1 | $16 |
| NVCTNuvectis Pharma, Inc. | 1 | $8 |
| KZIAKAZIA THERAPEUTICS LTD | 1 | $8 |
| PULMPulmatrix, Inc. | 3 | $4 |
| TLXTelix Pharmaceuticals Limited | 0 | $4 |
| GLMDGalmed Pharmaceuticals Ltd. | 2 | $1 |