| ABVXAbivax SA | 1,438,019 | $160.1M |
| PTGXProtagonist Therapeutics, Inc | 994,119 | $104.8M |
| ROIVRoivant Sciences Ltd. | 3,285,906 | $91.0M |
| IMVTImmunovant, Inc. | 2,679,010 | $66.5M |
| TERNTerns Pharmaceuticals, Inc. | 1,114,699 | $58.8M |
| CYTKCYTOKINETICS INC | 632,556 | $41.7M |
| CRNXCrinetics Pharmaceuticals, Inc. | 1,139,331 | $41.4M |
| DNLIDenali Therapeutics Inc. | 1,871,455 | $35.9M |
| BEAMBeam Therapeutics Inc. | 1,446,375 | $34.5M |
| ZLABZai Lab Ltd | 1,425,367 | $26.8M |
| SEPNSepterna, Inc. | 1,089,818 | $26.2M |
| VIRVir Biotechnology, Inc. | 2,744,714 | $24.6M |
| DBVTDBV Technologies S.A. | 1,012,866 | $21.2M |
| INSPInspire Medical Systems Inc. | 405,197 | $20.9M |
| SRRKScholar Rock Holding Corp | 407,273 | $20.0M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 211,450 | $18.4M |
| SYRESpyre Therapeutics, Inc. | 338,323 | $17.1M |
| CTMXCytomX Therapeutics, Inc. | 3,410,190 | $16.0M |
| PRTAPROTHENA CORP PUBLIC LTD CO | 1,581,443 | $15.4M |
| SNYSanofi | 316,939 | $15.3M |
| PCVXVaxcyte, Inc. | 259,137 | $15.1M |
| MNPRMonopar Therapeutics | 264,278 | $14.5M |
| ABUSArbutus Biopharma Corp | 3,133,175 | $14.1M |
| AMLXAmylyx Pharmaceuticals, Inc. | 1,000,604 | $13.9M |
| CLDXCelldex Therapeutics, Inc. | 427,816 | $13.6M |
| TSHATaysha Gene Therapies, Inc. | 2,979,429 | $13.3M |
| XENEXenon Pharmaceuticals Inc. | 228,899 | $13.3M |
| STROSUTRO BIOPHARMA, INC. | 524,441 | $13.1M |
| RVMDREVOLUTION MEDICINES, INC. | 133,893 | $13.0M |
| ELVNEnliven Therapeutics, Inc. | 329,540 | $12.9M |
| REPLReplimune Group, Inc. | 1,682,987 | $12.9M |
| CGONCG Oncology, Inc. | 185,699 | $12.6M |
| IVAInventiva S.A. | 2,174,398 | $12.1M |
| IONSIONIS PHARMACEUTICALS INC | 160,338 | $12.0M |
| NKTRNEKTAR THERAPEUTICS | 161,252 | $11.6M |
| IKTInhibikase Therapeutics, Inc. | 6,606,572 | $11.1M |
| SPRYARS Pharmaceuticals, Inc. | 1,361,536 | $10.9M |
| OVIDOvid Therapeutics Inc. | 4,544,113 | $10.1M |
| OKUROnKure Therapeutics, Inc. | 2,434,941 | $10.1M |
| REGNREGENERON PHARMACEUTICALS, INC. | 12,154 | $9.4M |
| MLTXMoonLake Immunotherapeutics | 477,137 | $8.9M |
| IRDOpus Genetics, Inc. | 1,849,004 | $8.4M |
| TEVATeva Pharmaceutical Industries Limited | 268,391 | $8.1M |
| SVRASavara Inc | 1,464,535 | $8.0M |
| MPLTMapLight Therapeutics, Inc. | 374,909 | $7.6M |
| LONALeonaBio, Inc. | 727,481 | $7.5M |
| EQEquillium, Inc. | 3,726,659 | $7.5M |
| VKTXViking Therapeutics, Inc. | 227,717 | $7.4M |
| DMRADamora Therapeutics, Inc. | 279,000 | $7.2M |
| URGNUroGen Pharma Ltd. | 395,459 | $7.1M |
| BBIOBridgeBio Pharma, Inc. | 94,292 | $7.0M |
| PRMEPrime Medicine, Inc. | 1,973,282 | $6.9M |
| VRTXVERTEX PHARMACEUTICALS INC / MA | 15,075 | $6.7M |
| KRROKorro Bio, Inc. | 540,054 | $6.1M |
| VRDNViridian Therapeutics, Inc.\DE | 304,422 | $6.0M |
| INSMINSMED Inc | 35,392 | $5.8M |
| SRPTSarepta Therapeutics, Inc. | 262,058 | $5.7M |
| KRYSKrystal Biotech, Inc. | 20,014 | $5.2M |
| ABOSAcumen Pharmaceuticals, Inc. | 2,156,334 | $5.1M |
| IVVDInvivyd, Inc. | 3,822,427 | $5.0M |
| TARAProtara Therapeutics, Inc. | 940,512 | $4.9M |
| AGIOAGIOS PHARMACEUTICALS, INC. | 140,672 | $4.8M |
| LLYELI LILLY & Co | 5,060 | $4.7M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 55,000 | $4.6M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 70,300 | $4.4M |
| BLTEBELITE BIO, INC | 26,880 | $4.3M |
| EVMNEvommune, Inc. | 184,062 | $4.2M |
| MLYSMineralys Therapeutics, Inc. | 154,686 | $4.2M |
| JANXJanux Therapeutics, Inc. | 298,546 | $4.1M |
| CLYMClimb Bio, Inc. | 597,662 | $4.1M |
| PALIPALISADE BIO, INC. | 2,264,845 | $4.0M |
| SPRBSPRUCE BIOSCIENCES, INC. | 58,600 | $3.8M |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 118,623 | $3.8M |
| LQDALiquidia Corp | 100,000 | $3.8M |
| ZURAZura Bio Ltd | 630,403 | $3.8M |
| ACLXArcellx, Inc. | 32,084 | $3.7M |
| GLUEMonte Rosa Therapeutics, Inc. | 215,752 | $3.5M |
| ONCBeOne Medicines Ltd. | 11,701 | $3.5M |
| CRBPCorbus Pharmaceuticals Holdings, Inc. | 366,781 | $3.4M |
| AVBPArriVent BioPharma, Inc. | 141,814 | $3.3M |
| PLRXPLIANT THERAPEUTICS, INC. | 2,585,126 | $3.3M |
| ATAIAtai Beckley N.V. | 913,242 | $3.2M |
| RLMDRELMADA THERAPEUTICS, INC. | 451,918 | $3.1M |
| CATXPerspective Therapeutics, Inc. | 749,335 | $3.1M |
| ELDNEledon Pharmaceuticals, Inc. | 974,421 | $3.0M |
| PHVSPharvaris N.V. | 105,528 | $3.0M |
| APLSApellis Pharmaceuticals, Inc. | 72,500 | $2.9M |
| QUREuniQure N.V. | 176,206 | $2.9M |
| EWTXEdgewise Therapeutics, Inc. | 90,599 | $2.9M |
| PEPGPepGen Inc. | 1,607,638 | $2.8M |
| CAPRCAPRICOR THERAPEUTICS, INC. | 90,593 | $2.8M |
| INOINOVIO PHARMACEUTICALS, INC. | 1,470,108 | $2.6M |
| DRUGBRIGHT MINDS BIOSCIENCES INC. | 33,900 | $2.5M |
| BIOABioAge Labs, Inc. | 135,560 | $2.4M |
| ALECAlector, Inc. | 1,050,000 | $2.3M |
| PFEPFIZER INC | 77,400 | $2.2M |
| BIIBBIOGEN INC. | 11,000 | $2.0M |
| CNTBConnect Biopharma Holdings Ltd | 742,400 | $1.9M |
| KPTIKaryopharm Therapeutics Inc. | 341,936 | $1.9M |
| SMMTSummit Therapeutics Inc. | 91,869 | $1.7M |
| GMEDGlobus Medical Inc. | 20,100 | $1.7M |
| NVONovo Nordisk A/S | 46,000 | $1.7M |
| ALKSAlkermes plc. | 46,400 | $1.6M |
| SLNOSOLENO THERAPEUTICS INC | 46,830 | $1.6M |
| RCKTRocket Pharmaceuticals Inc. | 432,500 | $1.5M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 29,642 | $1.5M |
| CNTACentessa Pharmaceuticals plc | 38,566 | $1.5M |
| FOLDAMICUS THERAPEUTICS, INC. | 105,000 | $1.5M |
| MAZEMaze Therapeutics, Inc. | 50,095 | $1.5M |
| UNHUnitedHealth Group Incorporated Common Stock (DE) | 5,501 | $1.5M |
| ADGMAdagio Medical Holdings Inc | 1,205,447 | $1.4M |
| KNSAKiniksa Pharmaceuticals International, plc | 26,913 | $1.3M |
| CRVSCorvus Pharmaceuticals, Inc. | 87,901 | $1.3M |
| MSLESatellos Bioscience Inc. | 222,555 | $1.3M |
| PMNProMIS Neurosciences Inc. | 95,350 | $1.2M |
| LXRXLEXICON PHARMACEUTICALS, INC. | 750,000 | $1.2M |
| SDGRSchrodinger, Inc. | 101,500 | $1.2M |
| XNCRXencor Inc | 93,665 | $1.1M |
| OABIOmniAb Inc. | 705,190 | $1.1M |
| FDMT4D Molecular Therapeutics, Inc. | 116,712 | $1.1M |
| KROSKeros Therapeutics, Inc. | 97,318 | $1.1M |
| DAWNDay One Biopharmaceuticals, Inc. | 49,923 | $1.1M |
| BMYBRISTOL MYERS SQUIBB CO | 17,500 | $1.1M |
| TNGXTango Therapeutics, Inc. | 50,000 | $1.0M |
| TNYATenaya Therapeutics, Inc. | 1,507,800 | $1.0M |
| MCKMcKesson Corporation | 1,200 | $1.0M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 18,200 | $1.0M |
| ORKAOruka Therapeutics, Inc. | 20,840 | $1.0M |
| FULCFulcrum Therapeutics, Inc. | 130,560 | $1.0M |
| BCRXBIOCRYST PHARMACEUTICALS INC | 105,000 | $1000K |
| GHGuardant Health Inc. | 10,000 | $924K |
| CBIOCRESCENT BIOPHARMA, INC. | 50,273 | $924K |
| CNTXContext Therapeutics Inc. | 351,094 | $920K |
| SLNSilence Therapeutics Plc | 172,157 | $907K |
| IBIOiBio, Inc. | 469,878 | $893K |
| BNTXBioNTech SE | 10,000 | $889K |
| GILDGILEAD SCIENCES, INC. | 6,351 | $885K |
| NRIXNurix Therapeutics, Inc. | 56,070 | $869K |
| DYNDyne Therapeutics, Inc. | 47,463 | $861K |
| ANLAdlai Nortye Ltd. | 117,909 | $816K |
| RNAAtrium Therapeutics Inc. | 57,688 | $771K |
| CMPXCompass Therapeutics, Inc. | 139,000 | $735K |
| NUVLNuvalent, Inc. | 6,942 | $711K |
| CGEMCullinan Therapeutics, Inc. | 50,000 | $711K |
| RAREUltragenyx Pharmaceutical Inc. | 33,400 | $700K |
| IDYAIDEAYA Biosciences, Inc. | 20,000 | $666K |
| GUTSFractyl Health Inc. | 1,428,571 | $654K |
| ENTAENANTA PHARMACEUTICALS INC | 51,357 | $649K |
| VERAVera Therapeutics, Inc. | 16,033 | $645K |
| VYNEVYNE Therapeutics Inc. | 1,063,899 | $636K |
| ARVNARVINAS, INC. | 57,591 | $610K |
| KZRKezar Life Sciences, Inc. | 81,933 | $608K |
| KLRSKalaris Therapeutics, Inc. | 100,000 | $577K |
| MIRMMirum Pharmaceuticals, Inc. | 6,200 | $573K |
| JAZZJazz Pharmaceuticals plc | 3,000 | $567K |
| ASMBASSEMBLY BIOSCIENCES, INC. | 19,947 | $554K |
| PRLDPrelude Therapeutics Inc | 152,825 | $523K |
| ACRSAclaris Therapeutics, Inc. | 132,426 | $497K |
| PRAXPraxis Precision Medicines, Inc. | 1,500 | $483K |
| ELANElanco Animal Health Inc | 20,000 | $479K |
| PHATPhathom Pharmaceuticals, Inc. | 42,900 | $477K |
| MDGLMADRIGAL PHARMACEUTICALS, INC. | 895 | $469K |
| WHWKWhitehawk Therapeutics, Inc. | 128,503 | $443K |
| VTGNVistagen Therapeutics, Inc. | 751,141 | $429K |
| TXMDTherapeuticsMD, Inc. | 209,210 | $423K |
| SNDXSyndax Pharmaceuticals Inc | 17,500 | $409K |
| TECXTectonic Therapeutic, Inc. | 13,001 | $402K |
| TRDAEntrada Therapeutics, Inc. | 30,500 | $385K |
| BHVNBiohaven Ltd. | 44,777 | $379K |
| MRKMerck & Co., Inc. | 3,140 | $378K |
| VSTMVerastem, Inc. | 71,100 | $377K |
| RGNXREGENXBIO Inc. | 44,416 | $372K |
| ACETAdicet Bio, Inc. | 53,827 | $367K |
| LEGNLegend Biotech Corp | 20,000 | $362K |
| SRZNSurrozen Inc. | 12,000 | $350K |
| ZNTLZentalis Pharmaceuticals, Inc. | 144,636 | $338K |
| BCYCBICYCLE THERAPEUTICS PLC | 71,298 | $331K |
| NBIXNEUROCRINE BIOSCIENCES INC | 2,500 | $329K |
| WVEWave Life Sciences Ltd. | 44,900 | $326K |
| KURAKura Oncology, Inc. | 40,000 | $325K |
| KPRXKiora Pharmaceuticals Inc. | 167,941 | $324K |
| CORTCORCEPT THERAPEUTICS INC | 8,000 | $322K |
| UPBUpstream Bio, Inc. | 35,000 | $315K |
| ANNXAnnexon, Inc. | 55,000 | $305K |
| GERNGERON CORP | 200,000 | $298K |
| PMVPPMV Pharmaceuticals, Inc. | 231,008 | $286K |
| JBIOJade Biosciences, Inc. | 20,000 | $281K |
| BCAXBicara Therapeutics Inc. | 13,705 | $273K |
| NTLAIntellia Therapeutics, Inc. | 19,517 | $250K |
| RPRXRoyalty Pharma plc | 5,000 | $240K |
| LRMRLarimar Therapeutics, Inc. | 52,745 | $237K |
| EOLSEvolus, Inc. | 55,859 | $230K |
| QTTBQ32 Bio Inc. | 35,000 | $225K |
| LGVNLongeveron Inc. | 200,000 | $208K |
| ANABANAPTYSBIO, INC | 3,698 | $205K |
| KALVKalVista Pharmaceuticals, Inc. | 10,000 | $201K |
| KYTXKyverna Therapeutics, Inc. | 22,428 | $194K |
| NUVBNuvation Bio Inc. | 43,500 | $187K |
| BNTCBenitec Biopharma Inc. | 17,500 | $186K |
| LPCNLipocine Inc. | 23,180 | $185K |
| RLYBRallybio Corp | 20,535 | $184K |
| RZLTRezolute, Inc. | 58,679 | $179K |
| QCLSQ/C TECHNOLOGIES, INC. | 50,000 | $173K |
| ERASErasca, Inc. | 10,000 | $162K |
| COYACoya Therapeutics, Inc. | 40,900 | $161K |
| HELPCYBIN INC. | 31,278 | $150K |
| STIMNeuronetics Inc. | 100,000 | $145K |
| ARDXARDELYX, INC. | 23,900 | $143K |
| IFRXInflaRx N.V. | 158,271 | $142K |
| ACHVACHIEVE LIFE SCIENCES, INC. | 47,800 | $141K |
| VYGRVoyager Therapeutics, Inc. | 35,000 | $135K |
| CMMBChemomab Therapeutics Ltd. | 80,000 | $126K |
| JSPRJasper Therapeutics Inc. | 140,000 | $123K |
| NEUPNeuphoria Therapeutics Inc. | 30,000 | $122K |
| MISTMilestone Pharmaceuticals Inc. | 100,000 | $119K |
| ARCTArcturus Therapeutics Holdings Inc. | 15,000 | $116K |
| MGNXMACROGENICS INC | 40,000 | $116K |
| CCCCC4 Therapeutics, Inc. | 43,000 | $113K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 35,000 | $107K |
| DSGNDesign Therapeutics, Inc. | 10,000 | $106K |
| GOSSGossamer Bio, Inc. | 287,531 | $94K |
| IMMXImmix Biopharma, Inc. | 10,000 | $91K |
| LITSLite Strategy, Inc. | 67,292 | $78K |
| VERUVERU INC. | 35,000 | $77K |
| KYNBKYNTRA BIO INC. | 10,469 | $71K |
| CLOVClover Health Investments Corp. | 40,000 | $70K |
| BMEABiomea Fusion, Inc. | 43,420 | $66K |
| OGNOrganon & Co. | 10,000 | $60K |
| ESPREsperion Therapeutics, Inc. | 21,400 | $59K |
| MREOMereo BioPharma Group plc | 150,000 | $50K |
| ANTXAN2 Therapeutics, Inc. | 13,861 | $47K |
| AQSTAquestive Therapeutics, Inc. | 10,000 | $42K |
| ATYRaTYR PHARMA INC | 50,685 | $40K |
| KALAKALA BIO, Inc. | 141,480 | $24K |
| CHRSCoherus Oncology, Inc. | 10,366 | $18K |
| PRQRProQR Therapeutics N.V. | 10,000 | $16K |