Lymphoblastic Leukemia

Oncology·MeSH: Precursor Cell Lymphoblastic Leukemia-Lymphoma

Prevalence

8.0 / 100K

Incidence

1.8 / 100K/yr

203 drugs in development·38 companies·5 clinical trials

Drug Pipeline by Phase

Approved(10)

Drug	Company
aucatzyl	Autolus Therapeutics plc (AUTL)
clofarabine	Mersana Therapeutics, Inc. (MRSN)
clofarabine	DR REDDYS LABORATORIES LTD (RDY)
clonoSEQ	Adaptive Biotechnologies Corp (ADPT)
doxorubicin	Amneal Pharmaceuticals, Inc. (AMRX)
kymriah	CELLULAR BIOMEDICINE GROUP, INC. (CMBG)
methotrexate	ELITE PHARMACEUTICALS INC /NV/ (ELTP)
nelarabine	NEXUS BIOPHARMA INC (NEXS)
nelarabine	Amneal Pharmaceuticals, Inc. (AMRX)
Rylaze / Enrylaze	Jazz Pharmaceuticals plc (JAZZ)

Phase 3(91)

Drug	Company
asciminib	GH Research PLC (GHRS)
Asparaginase Erwinia chrysanthemi	Cosmos Health Inc. (COSM)
Asparaginase Erwinia chrysanthemi	Assertio Holdings, Inc. (ASRT)
AZD0486	ASTRAZENECA PLC (AZN)
Bleomycin Sulfate	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Blinatumomab	Cosmos Health Inc. (COSM)
Blinatumomab	Crinetics Pharmaceuticals, Inc. (CRNX)
Blinatumomab	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Calaspargase	Filana Therapeutics Inc. (FLNA)
Calaspargase Pegol	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Calaspargase Pegol	Cosmos Health Inc. (COSM)
Calaspargase Pegol	Filana Therapeutics Inc. (FLNA)
Calaspargase Pegol	Assertio Holdings, Inc. (ASRT)
Calaspargase Pegol	Merus N.V. (MRUS)
CAR-T	Filana Therapeutics Inc. (FLNA)
CD22 CAR-transduced T cells	Filana Therapeutics Inc. (FLNA)
chemotherapy agents	TAKEDA PHARMACEUTICAL CO LTD (TKPHF)
Clofarabine	Merus N.V. (MRUS)
ctl019	Novartis AG (NVS)
CTL019	Novartis AG (NVS)
Cytarabine	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Cytarabine	Crinetics Pharmaceuticals, Inc. (CRNX)
Cytarabine	Cosmos Health Inc. (COSM)
Cytarabine	Assertio Holdings, Inc. (ASRT)
Dasatinib	Assertio Holdings, Inc. (ASRT)
Dasatinib	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Dasatinib	Cosmos Health Inc. (COSM)
Dasatinib	Crinetics Pharmaceuticals, Inc. (CRNX)
Daunorubicin	Cosmos Health Inc. (COSM)
Daunorubicin	Assertio Holdings, Inc. (ASRT)
Daunorubicin Hydrochloride	Assertio Holdings, Inc. (ASRT)
Daunorubicin Hydrochloride	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Dexrazoxane Hydrochloride	Assertio Holdings, Inc. (ASRT)
Gemtuzumab Ozogamicin	Assertio Holdings, Inc. (ASRT)
Hydrocortisone	Assertio Holdings, Inc. (ASRT)
Hydrocortisone	Merus N.V. (MRUS)
Hydrocortisone Sodium Succinate	Assertio Holdings, Inc. (ASRT)
hypercvad	AMGEN INC (AMGN)
idarubicin	GH Research PLC (GHRS)
Ifosfamide	Assertio Holdings, Inc. (ASRT)
Imatinib	Cosmos Health Inc. (COSM)
Imatinib Mesylate	Filana Therapeutics Inc. (FLNA)
Imatinib Mesylate	Assertio Holdings, Inc. (ASRT)
induction phase	GH Research PLC (GHRS)
inotuzumab	GH Research PLC (GHRS)
Inotuzumab	ENANTA PHARMACEUTICALS INC (ENTA)
Inotuzumab ozogamicin	Assertio Holdings, Inc. (ASRT)
Inotuzumab Ozogamicin	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Inotuzumab Ozogamicin	Filana Therapeutics Inc. (FLNA)
Isatuximab	Sanofi (SNY)
kte-c19	Kite Pharma, Inc. (KITE)
Leucovorin	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Leucovorin	Cosmos Health Inc. (COSM)
Leucovorin Calcium	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Leucovorin Calcium	Cosmos Health Inc. (COSM)
Levoleucovorin	Assertio Holdings, Inc. (ASRT)
Liposome-encapsulated Daunorubicin-Cytarabine	Assertio Holdings, Inc. (ASRT)
low-intensity chemotherapy regimen	AMGEN INC (AMGN)
maintenance	GH Research PLC (GHRS)
Mercaptopurine	Cosmos Health Inc. (COSM)
Mercaptopurine	Assertio Holdings, Inc. (ASRT)
Mercaptopurine	ENANTA PHARMACEUTICALS INC (ENTA)
Mercaptopurine Oral Suspension	Assertio Holdings, Inc. (ASRT)
Mercaptopurine Oral Suspension	Cosmos Health Inc. (COSM)
Mesna	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Mesna	Crinetics Pharmaceuticals, Inc. (CRNX)
Mesna	Assertio Holdings, Inc. (ASRT)
Mesna	Merus N.V. (MRUS)
Mitoxantrone Hydrochloride	Assertio Holdings, Inc. (ASRT)
Ofatumumab	ENANTA PHARMACEUTICALS INC (ENTA)
Pegaspargase	Merus N.V. (MRUS)
Pegaspargase	ENANTA PHARMACEUTICALS INC (ENTA)
Pegaspargase	Cosmos Health Inc. (COSM)
Pegaspargase	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Ponatinib	ENANTA PHARMACEUTICALS INC (ENTA)
Ponatinib Hydrochloride	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Ponatinib Hydrochloride	Crinetics Pharmaceuticals, Inc. (CRNX)
Procarbazine Hydrochloride	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Selumetinib Sulfate	Merus N.V. (MRUS)
Therapeutic Hydrocortisone	Assertio Holdings, Inc. (ASRT)
Thioguanine	ENANTA PHARMACEUTICALS INC (ENTA)
Thioguanine	Assertio Holdings, Inc. (ASRT)
Thioguanine	Merus N.V. (MRUS)
Thioguanine	Cosmos Health Inc. (COSM)
Vinblastine Sulfate	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Vincristine	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Vincristine	Cosmos Health Inc. (COSM)
Vincristine Sulfate	Crinetics Pharmaceuticals, Inc. (CRNX)
Vincristine Sulfate	AXIM BIOTECHNOLOGIES, INC. (AXIM)
Vincristine Sulfate	Cosmos Health Inc. (COSM)
Vincristine Sulfate	Assertio Holdings, Inc. (ASRT)

Phase 2(72)

Drug	Company
6-Mercaptopurine	Assertio Holdings, Inc. (ASRT)
Acetaminophen	ENANTA PHARMACEUTICALS INC (ENTA)
Acetaminophen	Assertio Holdings, Inc. (ASRT)
Acetaminophen	Merus N.V. (MRUS)
Asparaginase Erwinia chrysanthemi	AXIM BIOTECHNOLOGIES, INC. (AXIM)
atg	GH Research PLC (GHRS)
AUCATZYL/obe-cel	Autolus Therapeutics plc (AUTL)
Blinatumomab	Merus N.V. (MRUS)
Bortezomib	Structure Therapeutics Inc. (GPCR)
Calaspargase	Assertio Holdings, Inc. (ASRT)
cd19+	GH Research PLC (GHRS)
cd45ra-depleted dli	GH Research PLC (GHRS)
Cetuximab Sarotalocan Sodium	Merus N.V. (MRUS)
CLLS52	Cellectis S.A. (CLLS)
Clofarabine	Structure Therapeutics Inc. (GPCR)
Clofarabine	ENANTA PHARMACEUTICALS INC (ENTA)
cnct19	CASI Pharmaceuticals, Inc (DE) (CASI)
Cytarabine	ARROWHEAD PHARMACEUTICALS, INC. (ARWR)
Cytarabine	Cidara Therapeutics, Inc. (CDTX)
Cytarabine	PROTHENA CORP PUBLIC LTD CO (PRTA)
Dasatinib	Merus N.V. (MRUS)
Diphenhydramine	Assertio Holdings, Inc. (ASRT)
Diphenhydramine	ENANTA PHARMACEUTICALS INC (ENTA)
Diphenhydramine	Merus N.V. (MRUS)
Diphenhydramine	Cidara Therapeutics, Inc. (CDTX)
Diphenhydramine	PROTHENA CORP PUBLIC LTD CO (PRTA)
Etoposide	Structure Therapeutics Inc. (GPCR)
Filgrastim	Filana Therapeutics Inc. (FLNA)
filgrastim or equivalent	Sanofi (SNY)
fludarabine	Sanofi (SNY)
fludarabine	HWH International Inc. (HWH)
g-csf	GH Research PLC (GHRS)
Hydrocortisone	PROTHENA CORP PUBLIC LTD CO (PRTA)
Hydrocortisone	Cidara Therapeutics, Inc. (CDTX)
Hydrocortisone	ARROWHEAD PHARMACEUTICALS, INC. (ARWR)
Hydrocortisone	Structure Therapeutics Inc. (GPCR)
Hydrocortisone	ENANTA PHARMACEUTICALS INC (ENTA)
idarubicin	Sanofi (SNY)
Inotuzumab	Assertio Holdings, Inc. (ASRT)
Inotuzumab ozogamicin	ARROWHEAD PHARMACEUTICALS, INC. (ARWR)
Inotuzumab ozogamicin	Structure Therapeutics Inc. (GPCR)
Inotuzumab ozogamicin	ENANTA PHARMACEUTICALS INC (ENTA)
Inotuzumab ozogamicin	PROTHENA CORP PUBLIC LTD CO (PRTA)
Inotuzumab ozogamicin	Cidara Therapeutics, Inc. (CDTX)
isatuximab	Sanofi (SNY)
l - asparaginase	Sanofi (SNY)
l - asparginase	Sanofi (SNY)
liposomal daunorubicin	Sanofi (SNY)
mb-cart19.1	CELLULAR BIOMEDICINE GROUP, INC. (CMBG)
mercaptopurine	Merus N.V. (MRUS)
mitoxantrone	Sanofi (SNY)
Obe-cel (AUTO1)	Autolus Therapeutics plc (AUTL)
Ofatumumab	Merus N.V. (MRUS)
Ofatumumab	Structure Therapeutics Inc. (GPCR)
Ofatumumab	Filana Therapeutics Inc. (FLNA)
out-of-specification obecabtagene autoleucel	Autolus Therapeutics plc (AUTL)
pegaspargase asparaginase	Sanofi (SNY)
Pegfilgrastim	Filana Therapeutics Inc. (FLNA)
Ponatinib	Filana Therapeutics Inc. (FLNA)
post-remission	GH Research PLC (GHRS)
post-transplant abatacept	GH Research PLC (GHRS)
post-transplant tacrolimus	GH Research PLC (GHRS)
re-induction phase	GH Research PLC (GHRS)
Sodium Thiosulfate	Merus N.V. (MRUS)
tcrα/β+	GH Research PLC (GHRS)
tecartus	GH Research PLC (GHRS)
UCART22	Cellectis S.A. (CLLS)
Vinblastine Sulfate	Merus N.V. (MRUS)
vincristine	Sanofi (SNY)
vincristine	Merus N.V. (MRUS)
Vincristine Sulfate	Merus N.V. (MRUS)
Vincristine Sulfate Liposome	Structure Therapeutics Inc. (GPCR)

Phase 1(7)

Drug	Company
ADCT-602	ADC Therapeutics SA (ADCT)
blinatumomab	AMGEN INC (AMGN)
Blinatumomab	AbbVie Inc. (ABBV)
cd19-car t-cells	GH Research PLC (GHRS)
Dasatinib	AbbVie Inc. (ABBV)
kur-502	Athenex, Inc. (ATNX)
YK012	Merus N.V. (MRUS)

Preclinical(4)

Drug	Company
BCR-ABL TKI	Theseus Pharmaceuticals, Inc. (THRX)
hicar-t	Orgenesis Inc. (ORGS)
pf743	Pfenex Inc. (PFNX)
pf745	Pfenex Inc. (PFNX)

Unknown(1)

Drug	Company
puzolcabtagene autoleucel	PRECISION BIOSCIENCES INC (DTIL)

Phase 1/Phase 2(6)

Drug	Company
asciminib adult formulation	Novartis AG (NVS)
asciminib pediatric formulation	Novartis AG (NVS)
auto1	Autolus Therapeutics plc (AUTL)
AUTO1/22	Autolus Therapeutics plc (AUTL)
blinatumomab	Novartis AG (NVS)
vincristine	Novartis AG (NVS)

Phase 2/Phase 3(9)

Drug	Company
6-mercaptopurine	GH Research PLC (GHRS)
asparaginase erwinia chrysanthemi	GH Research PLC (GHRS)
asparaginase erwinia chrysanthemi	GH Research PLC (GHRS)
blinatumomab	GH Research PLC (GHRS)
calaspargase	GH Research PLC (GHRS)
calaspargase pegol	GH Research PLC (GHRS)
erwinase	GH Research PLC (GHRS)
pegaspargase	GH Research PLC (GHRS)
post-transplant mycophenolate mofetil	GH Research PLC (GHRS)

Phase 4(3)

Drug	Company
Clofarabine	Filana Therapeutics Inc. (FLNA)
ponatinib	TAKEDA PHARMACEUTICAL CO LTD (TKPHF)
ponatinib	Takeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock) (TAK)

Compare drugs

aucatzyl vs clofarabine aucatzyl vs clonoSEQ aucatzyl vs doxorubicin

Frequently asked questions

How many drugs are in development for Lymphoblastic Leukemia?

BioSniper tracks 203 drugs in development for Lymphoblastic Leukemia across 38 companies.

How many clinical trials target Lymphoblastic Leukemia?

There are 5 clinical trials targeting Lymphoblastic Leukemia tracked by BioSniper.

What is the prevalence of Lymphoblastic Leukemia?

The estimated prevalence of Lymphoblastic Leukemia is approximately 8.0 per 100,000 population.

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