AF

Cardiovascular

243 drugs in development·121 companies·1 clinical trial

Drug Pipeline by Phase

Approved(100)

Drug	Company
ABRAXANE	ImmunityBio, Inc. (IBRX)
acetylcysteine	ENGENE HOLDINGS INC. (ENGN)
afinitor	Novartis AG (NVS)
alendronate	Mylan II B.V. (MYL)
almotriptan malate	Mylan II B.V. (MYL)
AMNIOCORD	MiMedx Group Inc (MDXG)
AMNIOEFFECT	MiMedx Group Inc (MDXG)
axitinib	Aptinyx Inc. (APTX)
bexarotene	Amneal Pharmaceuticals, Inc. (AMRX)
braftovi	ARRAY BIOPHARMA INC (ARRY)
bupropion	Design Therapeutics, Inc. (DSGN)
bupropion	Prestige Consumer Healthcare Inc. (PBH)
bupropion	Impax Laboratories, LLC (IPXL)
bupropion	AlphaTON Capital Corp (ATON)
butalbital	LANNETT CO INC (LCI)
butalbital	QIAGEN N.V. (QGEN)
butalbital	Optec International, Inc. (GM)
cayston	GILEAD SCIENCES, INC. (GILD)
chenodiol	Optec International, Inc. (GM)
clobetasol propionate ophthalmic suspension 0.05%	HYPERION DEFI, INC. (HYPD)
clofarabine	Mersana Therapeutics, Inc. (MRSN)
clofarabine	DR REDDYS LABORATORIES LTD (RDY)
cromolyn	AGILE THERAPEUTICS INC (AGRX)
diphenhydramine	ACHIEVE LIFE SCIENCES, INC. (ACHV)
diphenhydramine	Miromatrix Medical Inc. (MIRO)
docetaxel	Amneal Pharmaceuticals, Inc. (AMRX)
Double - Coptis Suppository	China Health Industries Holdings, Inc. (CHHE)
drug application	Liquidia Corp (LQDA)
emblaveo	AbbVie Inc. (ABBV)
EPICORD	MiMedx Group Inc (MDXG)
esomeprazole magnesium	EXELIXIS, INC. (EXEL)
everolimus	Mylan II B.V. (MYL)
gloperba	SCILEX HOLDING CO (SCLX)
hp+detect™	BIOMERICA INC (BMRA)
ibrance	PFIZER INC (PFE)
iluvien	ALIMERA SCIENCES INC (ALIM)
ILUVIEN	ANI PHARMACEUTICALS INC (ANIP)
imatinib	Teva Pharmaceutical Industries Limited (TEVA)
imatinib	Mylan II B.V. (MYL)
imatinib	Aptinyx Inc. (APTX)
imatinib	SUNSET ISLAND GROUP (SUN)
imatinib	DR REDDYS LABORATORIES LTD (RDY)
imatinib	Amneal Pharmaceuticals, Inc. (AMRX)
Imbruvica	Royalty Pharma plc (RPRX)
imipramine	OXFORD IMMUNOTEC GLOBAL PLC (OXFD)
imkeldi	CG Oncology, Inc. (CGON)
Indometacin and Furazolidone Suppositories	China Health Industries Holdings, Inc. (CHHE)
Inluriyo	ELI LILLY & Co (LLY)
INVEGA HAFYERA / BYANNLI	Alkermes plc. (ALKS)
INVEGA SUSTENNA / XEPLION	Alkermes plc. (ALKS)
jaypirca	LOXO ONCOLOGY, INC. (LOXO)
Jaypirca	ELI LILLY & Co (LLY)
Jaypirca®	ELI LILLY & Co (LLY)
kalydeco	VERTEX PHARMACEUTICALS INC / MA (VRTX)
ksort	IMMUCOR INC (BLUD)
lamotrigine	Teva Pharmaceutical Industries Limited (TEVA)
letairis	GILEAD SCIENCES, INC. (GILD)
leucovorin calcium preservative free	Seagen Inc. (SGEN)
leucovorin calcium preservative free	Mylan II B.V. (MYL)
mekinist	Novartis AG (NVS)
mektovi	ARRAY BIOPHARMA INC (ARRY)
mesalamine	Amneal Pharmaceuticals, Inc. (AMRX)
multaq	Sanofi (SNY)
naftifine	Amneal Pharmaceuticals, Inc. (AMRX)
nanoss strata	Xtant Medical Holdings, Inc. (XTNT)
neoprofen	Ultragenyx Pharmaceutical Inc. (RARE)
neostigmine methyl	Amphastar Pharmaceuticals, Inc. (AMPH)
nexobrid	MediWound Ltd. (MDWD)
Niktimvo	Syndax Pharmaceuticals Inc (SNDX)
nilutamide	ANI PHARMACEUTICALS INC (ANIP)
nPulse Console	Pulse Biosciences Inc Common Stock (DE) (PLSE)
ojemda	Day One Biopharmaceuticals, Inc. (DAWN)
Olumiant	ELI LILLY & Co (LLY)
Olumiant®	ELI LILLY & Co (LLY)
opcicon one-step	SUNSET ISLAND GROUP (SUN)
opdivo qvantig	BRISTOL MYERS SQUIBB CO (BMY)
ozurdex	AbbVie Inc. (ABBV)
paclitaxel	Mylan II B.V. (MYL)
paliperidone	Inventiva S.A. (IVA)
promacta	Novartis AG (NVS)
propafenone	Mylan II B.V. (MYL)
propylgallate	CHINA PHARMA HOLDINGS, INC. (CPHI)
Propylgallate for Injection	CHINA PHARMA HOLDINGS, INC. (CPHI)
simpligraft	Xtant Medical Holdings, Inc. (XTNT)
simplimax	Xtant Medical Holdings, Inc. (XTNT)
sirolimus	Amneal Pharmaceuticals, Inc. (AMRX)
timolol	Amneal Pharmaceuticals, Inc. (AMRX)
tobi podhaler	Viatris Inc (VTRS)
trikafta	VERTEX PHARMACEUTICALS INC / MA (VRTX)
trivium	Xtant Medical Holdings, Inc. (XTNT)
Tyvyt	ELI LILLY & Co (LLY)
Tyvyt®	ELI LILLY & Co (LLY)
ultramist	SANUWAVE Health Inc. (SNWV)
ursodiol	Optec International, Inc. (GM)
venlafaxine	Teva Pharmaceutical Industries Limited (TEVA)
veregen	ANI PHARMACEUTICALS INC (ANIP)
vykoura	Kaya Holdings, Inc. (KAYS)
zafirlukast	DR REDDYS LABORATORIES LTD (RDY)
Zenocutuzumab (Zeno) / BIZENGRI® (zenocutuzumab-zbco)	Merus N.V. (MRUS)
zoledronic acid	Amneal Pharmaceuticals, Inc. (AMRX)

Phase 3(49)

Drug	Company
A10 and AS2-1 Antineoplaston	BURZYNSKI RESEARCH INSTITUTE INC (BZYR)
Abatacept	Crinetics Pharmaceuticals, Inc. (CRNX)
Abatacept	ENANTA PHARMACEUTICALS INC (ENTA)
abelacimab	Dianthus Therapeutics, Inc. /DE/ (DNTH)
Amivantamab + FOLFIRI	IGM Biosciences, Inc. (IGMS)
Androgen-deprivation Therapy	Crinetics Pharmaceuticals, Inc. (CRNX)
APL-3007, pegcetacoplan	Apellis Pharmaceuticals, Inc. (APLS)
axatilimab	Incyte Corp. (INCY)
belumosudil	Sanofi (SNY)
best available therapy	Incyte Corp. (INCY)
best available treatment	Incyte Corp. (INCY)
Bicalutamide	Myovant Sciences Ltd. (MYOV)
Consolidation Therapy	Crinetics Pharmaceuticals, Inc. (CRNX)
Encorafenib	IGM Biosciences, Inc. (IGMS)
extracorporeal photopheresis	Incyte Corp. (INCY)
Flutamide	Myovant Sciences Ltd. (MYOV)
golidocitinib	Crinetics Pharmaceuticals, Inc. (CRNX)
golidocitinib	Merus N.V. (MRUS)
imatinib	Incyte Corp. (INCY)
imu-856	IMMUNIC, INC. (IMUX)
inca034176	Incyte Corp. (INCY)
infliximab	Incyte Corp. (INCY)
itacitinib	Incyte Corp. (INCY)
itolizumab	Equillium, Inc. (EQ)
lumateperone	Intra-Cellular Therapies, Inc. (ITCI)
lumateperone LAI	Intra-Cellular Therapies, Inc. (ITCI)
Maintenance Therapy	Crinetics Pharmaceuticals, Inc. (CRNX)
mechanistic target of rapamycin inhibitors	Incyte Corp. (INCY)
mycophenolate mofetil	Incyte Corp. (INCY)
Nilutamide	Myovant Sciences Ltd. (MYOV)
nPulse Cardiac Catheter System	Pulse Biosciences Inc Common Stock (DE) (PLSE)
nPulse Cardiac Surgical Clamp (nsPFA Cardiac Surgery System)	Pulse Biosciences Inc Common Stock (DE) (PLSE)
pacritinib	GH Research PLC (GHRS)
Pegcetacoplan	Apellis Pharmaceuticals, Inc. (APLS)
Pegcetacoplan (systemic)	Apellis Pharmaceuticals, Inc. (APLS)
pentostatin	Incyte Corp. (INCY)
Plinabulin	BeyondSpring Inc. (BYSI)
prochymal	Mesoblast Limited (MESO)
Re-induction Therapy	Crinetics Pharmaceuticals, Inc. (CRNX)
remestemcel-l-rknd	Mesoblast Limited (MESO)
Rescue medications for sacituzumab tirumotecan	Merus N.V. (MRUS)
revita dmr system	Fractyl Health Inc. (GUTS)
Rina-S	Merus N.V. (MRUS)
sacituzumab govitecan	Phoenix Life Sciences International Limited. (PLSI)
sdatev	Humacyte Inc. (HUMA)
surzebiclimab	BeOne Medicines Ltd. (ONC)
Systemic pegcetacoplan	Apellis Pharmaceuticals, Inc. (APLS)
tacrolimus	Incyte Corp. (INCY)
Zipalertinib (CLN-081/TAS6417)	Cullinan Therapeutics, Inc. (CGEM)

Phase 2(29)

Drug	Company
Abiraterone Acetate	ENANTA PHARMACEUTICALS INC (ENTA)
Amivantamab	IGM Biosciences, Inc. (IGMS)
Amivantamab IV	IGM Biosciences, Inc. (IGMS)
argx-117	ARGENX SE (ARGX)
axa1957	Axcella Health Inc. (AXLA)
BDTX-1535	Black Diamond Therapeutics, Inc. (BDTX)
Belumosudil	Crinetics Pharmaceuticals, Inc. (CRNX)
Bicalutamide	Janux Therapeutics, Inc. (JANX)
Bicalutamide	ENANTA PHARMACEUTICALS INC (ENTA)
Degarelix	ENANTA PHARMACEUTICALS INC (ENTA)
Degarelix	Myovant Sciences Ltd. (MYOV)
Degarelix	Royalty Pharma plc (RPRX)
Degarelix	Janux Therapeutics, Inc. (JANX)
Flutamide	Janux Therapeutics, Inc. (JANX)
Flutamide	ENANTA PHARMACEUTICALS INC (ENTA)
Goserelin Acetate	Janux Therapeutics, Inc. (JANX)
Interleukin-2	ENANTA PHARMACEUTICALS INC (ENTA)
Iparomlimab and Tuvonralimab	IGM Biosciences, Inc. (IGMS)
Nilutamide	Janux Therapeutics, Inc. (JANX)
Nilutamide	ENANTA PHARMACEUTICALS INC (ENTA)
Obinutuzumab	Filana Therapeutics Inc. (FLNA)
Obinutuzumab	ARROWHEAD PHARMACEUTICALS, INC. (ARWR)
Obinutuzumab	PROTHENA CORP PUBLIC LTD CO (PRTA)
Obinutuzumab	Cidara Therapeutics, Inc. (CDTX)
Obinutuzumab	Structure Therapeutics Inc. (GPCR)
regn7508	REGENERON PHARMACEUTICALS, INC. (REGN)
regn9933	REGENERON PHARMACEUTICALS, INC. (REGN)
Sacituzumab Govitecan	Amneal Pharmaceuticals, Inc. (AMRX)
VK2809	Viking Therapeutics, Inc. (VKTX)

Phase 1(14)

Drug	Company
ADXS-504	Ayala Pharmaceuticals, Inc. (ADXS)
ALPHA-1062 original nasal formulation (Phase I studies)	Alpha Cognition Inc. (ACOG)
amt-126	Applied Molecular Transport Inc. (AMTI)
Axatilimab	Syndax Pharmaceuticals Inc (SNDX)
BDTX-4933	Black Diamond Therapeutics, Inc. (BDTX)
BET Bromodomain Inhibitor ZEN-3694	Amneal Pharmaceuticals, Inc. (AMRX)
bms-986004	GH Research PLC (GHRS)
C-reactive protein and procalcitonin dosages	ENANTA PHARMACEUTICALS INC (ENTA)
Encorafenib	ENANTA PHARMACEUTICALS INC (ENTA)
EO-3021	Elevation Oncology, Inc. (ELEV)
hutrukin	XBiotech Inc. (XBIT)
Megadose Drug Combination	Cell Source, Inc. (CLCS)
Rescue Medications	Merus N.V. (MRUS)
sulopenem	Iterum Therapeutics plc (ITRM)

Preclinical(11)

Drug	Company
AGTX-2003 (RTI-1092769)	Agentix Corp. (AGTX)
hydrogel candidates for nafld/nash	GELESIS HOLDINGS, INC. (GLS)
isobutanol	EXOZYMES INC. (EXOZ)
jkb-122	Biostax Corp. (BTAX)
mar-fg-001	MARIZYME, INC. (MRZM)
nm-003	9 METERS BIOPHARMA, INC. (NMTR)
oral factor d inhibitors	ACHILLION PHARMACEUTICALS INC (ACHN)
Pan-mutant BRAF degrader program (proprietary)	Nurix Therapeutics, Inc. (NRIX)
Pan-mutant BRAF program (mutant BRAF degraders)	Nurix Therapeutics, Inc. (NRIX)
STAC-BBB	SANGAMO THERAPEUTICS, INC (SGMO)
THE-349	Theseus Pharmaceuticals, Inc. (THRX)

Unknown(16)

Drug	Company
AVIPure AAV affinity resins (AAV2, AAV8, AAV9, AAV5)	REPLIGEN CORP (RGEN)
brilaroxazine	REVIVA PHARMACEUTICALS HOLDINGS, INC. (RVPH)
CellFX nsPFA 360° Cardiac Catheter	Pulse Biosciences Inc Common Stock (DE) (PLSE)
CellFX nsPFA Cardiac Clamp	Pulse Biosciences Inc Common Stock (DE) (PLSE)
gencaro	Oruka Therapeutics, Inc. (ORKA)
helix transendocardial delivery catheter system	BioCardia, Inc. (BCDA)
legalon	Mylan II B.V. (MYL)
NGL-Impact A and NGL-Impact HipH (affinity ligands)	REPLIGEN CORP (RGEN)
nspfa cardiac surgical system	Pulse Biosciences Inc Common Stock (DE) (PLSE)
osteovive	Xtant Medical Holdings, Inc. (XTNT)
Precision DNA libraries	Twist Bioscience Corp (TWST)
tafinlar/mekinist	Novartis AG (NVS)
TangenX (SIUS, PRO, SC, SIUS Gamma)	REPLIGEN CORP (RGEN)
TangenX FS TFF cassettes	REPLIGEN CORP (RGEN)
The Satchel™	American Cannabis Company, Inc. (AMMJ)
VOC platform (NISD co-development)	Ainos Inc. (AIMD)

BLA Filed(1)

Drug	Company
belumosudil	Kadmon Holdings, Inc. (KDMN)

N/A(2)

Drug	Company
Optimized Medical Therapy for Atrial Fibrillation	Crinetics Pharmaceuticals, Inc. (CRNX)
Sitz-Markers	UNITED THERAPEUTICS Corp (UTHR)

Phase 1/Phase 2(8)

Drug	Company
brimarafenib	SpringWorks Therapeutics, Inc. (SWTX)
dcc-3116	Deciphera Pharmaceuticals, Inc. (DCPH)
eli-007	Elicio Therapeutics, Inc. (ELTX)
envometinib	Immuneering Corp (IMRX)
eq001	Equillium, Inc. (EQ)
regn7041	REGENERON PHARMACEUTICALS, INC. (REGN)
syn-004	Theriva Biologics, Inc. (TOVX)
WVE-008	Wave Life Sciences Ltd. (WVE)

Phase 2/Phase 3(1)

Drug	Company
tecarfarin	Cadrenal Therapeutics, Inc. (CVKD)

Phase 4(12)

Drug	Company
Belumosudil	Sanofi (SNY)
Belumosudil mesylate	Sanofi (SNY)
Bicalutamide	Royalty Pharma plc (RPRX)
flecainide	CYTOKINETICS INC (CYTK)
Flutamide	Royalty Pharma plc (RPRX)
ibrutinib	Incyte Corp. (INCY)
Nicotine Replacement Therapy	Crinetics Pharmaceuticals, Inc. (CRNX)
Nilutamide	Royalty Pharma plc (RPRX)
ocrelizumab infusion	GH Research PLC (GHRS)
pantoprazole	GH Research PLC (GHRS)
rebamipide	GH Research PLC (GHRS)
Sotalol or Amiodarone	CYTOKINETICS INC (CYTK)

Compare drugs

ABRAXANE vs acetylcysteine ABRAXANE vs afinitor ABRAXANE vs alendronate

Frequently asked questions

How many drugs are in development for AF?

BioSniper tracks 243 drugs in development for AF across 121 companies.

How many clinical trials target AF?

There are 1 clinical trial targeting AF tracked by BioSniper.

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