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abatacept

Generic: abatacept·Brand: Orencia

abatacept: 11 clinical trials tracked.

abatacept evidence translation

What we can confirm

11 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about abatacept, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence7 indications · 0 study sponsors
Clinical Trial Registry Records (11)showing 10 most recent

Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease

NCT07616154Registry updated 2026-07-23·Phase 2
Recruiting

Primary endpoint: GVHD-free and rejection free survival (GRFS)

Interventionalopen45 targetStarted 2026-09Completion 2035-091 site · United StatesSt. Jude Children's Research Hospital

A Phase I Trial of Azacitidine and Abatacept in Relapsed or Refractory T-Cell Lymphoma

NCT07388563Registry updated 2026-02-20·Phase 1
Not yet recruiting

Primary endpoint: Arm 2: To estimate the CRR of the combination of azacitidine and abatacept.

Interventionalopen20 targetStarted 2026-02Completion 2027-121 site · United StatesNational Cancer Institute (NCI)

Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis

NCT06654882Registry updated 2026-02-20·Phase 3
Recruiting

Primary endpoint: Number of participants with MiDA

InterventionalRandomizedopen400 targetStarted 2026-01Completion 2026-124 sites · United StatesDuke University

An Open-Label Phase I Study of JAK Inhibitor Ruxolitinib With and Without CTLA-4 Ig Abatacept for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

NCT06008808Registry updated 2026-04-22·Phase 1
Recruiting

Primary endpoint: Cumulative incidence of graft failure

Interventionalopen41 targetStarted 2024-05Completion 2027-111 site · United StatesWashington University School of Medicine

Rituximab-pvvr and Abatacept vs Rituximab-pvvr Alone in New Onset Type 1 Diabetes

NCT03929601Registry updated 2026-02-19·Phase 2
Active, not recruiting

Primary endpoint: C-Peptide Response to 2-hr MMTT at 24 months post-randomization

InterventionalRandomizedtriple74 targetStarted 2023-10Completion 2029-0319 sites · Australia, United StatesNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Abatacept Combined With Nasal Insulin to Preserve Beta-cell Function in Recently-diagnosed Type 1 Diabetes

NCT05742243Registry updated 2025-12-24·Phase 2
Completed

Primary endpoint: Beta-cell function at 48 weeks

InterventionalRandomizedtriple68 enrolledStarted 2023-02Completion 2025-096 sites · AustraliaMelbourne Health

A Randomized Double-Blind Trial of Abatacept Extended Dosing Versus Abatacept Short-term Dosing for Graft Versus Host Disease Prophylaxis: "ABA3"

NCT04380740Registry updated 2026-05-11·Phase 2
Recruiting

Primary endpoint: Severe AGVHD-free, severe CGVHD-free, relapse-free survival (SGRFS)

InterventionalRandomizedtriple160 targetStarted 2022-03Completion 2028-0615 sites · United StatesBoston Children's Hospital

Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease

NCT04925375Registry updated 2026-07-22·Phase 2
Recruiting

Primary endpoint: High Resolution CT Scan of the chest (HRCT)

InterventionalRandomizedquadruple38 targetStarted 2021-07Completion 2028-076 sites · United StatesChildren's Hospital Medical Center, Cincinnati

Acute GVHD Suppression Using Costimulation Blockade to Expand Non-malignant Transplant (ASCENT)

NCT03924401Registry updated 2026-02-25·Phase 2

Primary endpoint: Event-free survival

Interventionalopen30 targetStarted 2019-08Completion 2027-039 sites · United StatesEmory University

To Demonstrate the Ability of Abatacept in Comparison to Placebo to Obtain a Low Disease Activity [PMR-AS (CRP) Lower or Equal to 10] Without GCs (Prednisone or Prednisolone) at Week 12 in Early Onset PMR Patients.

NCT03632187Registry updated 2026-06-08·Phase 3
Completed

Primary endpoint: Following of one biological parameter (CRP)

InterventionalRandomizeddouble34 enrolledStarted 2018-12Completion 2022-065 sites · FranceUniversity Hospital, Brest