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| LLYELI LILLY & Co | 6,776,752 | $6.23B |
| JNJJOHNSON & JOHNSON | 8,704,882 | $2.13B |
| MRKMerck & Co., Inc. | 11,986,822 | $1.44B |
| PFEPFIZER INC | 44,365,635 | $1.25B |
| ABBVAbbVie Inc. | 5,601,515 | $1.22B |
| NVONovo Nordisk A/S | 31,024,311 | $1.14B |
| AMGNAMGEN INC | 2,141,213 | $753.4M |
| REGNREGENERON PHARMACEUTICALS, INC. | 974,120 | $752.6M |
| GILDGILEAD SCIENCES, INC. | 5,110,058 | $712.2M |
| MRNAModerna, Inc. | 12,575,740 | $638.8M |
| BMYBRISTOL MYERS SQUIBB CO | 10,166,789 | $616.6M |
| PMPhilip Morris International Inc | 3,578,246 | $591.6M |
| VRTXVERTEX PHARMACEUTICALS INC / MA | 1,283,721 | $573.2M |
| UTHRUNITED THERAPEUTICS Corp | 862,496 | $511.4M |
| AZNASTRAZENECA PLC | 2,546,841 | $502.3M |
| GMOptec International, Inc. | 6,291,710 | $468.7M |
| ABTABBOTT LABORATORIES | 4,138,099 | $424.9M |
| TEVATeva Pharmaceutical Industries Limited | 13,195,215 | $397.4M |
| MCKMcKesson Corporation | 365,540 | $316.3M |
| BBIOBridgeBio Pharma, Inc. | 3,607,243 | $267.9M |
| ELVElevance Health Inc. | 907,229 | $265.6M |
| BIIBBIOGEN INC. | 1,434,199 | $262.9M |
| RVMDREVOLUTION MEDICINES, INC. | 2,229,085 | $216.8M |
| ZTSZoetis Inc. | 1,770,864 | $209.3M |
| NVSNovartis AG | 1,353,981 | $206.8M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 596,768 | $197.5M |
| CAHCardinal Health Inc. | 855,895 | $180.9M |
| INSMINSMED Inc | 1,078,930 | $176.4M |
| ARGXARGENX SE | 239,292 | $174.7M |
| VKTXViking Therapeutics, Inc. | 4,820,309 | $156.9M |
| RIOTRiot Platforms, Inc. | 12,256,030 | $151.5M |
| CYTKCYTOKINETICS INC | 2,222,751 | $146.5M |
| ABVXAbivax SA | 1,284,782 | $143.1M |
| MDGLMADRIGAL PHARMACEUTICALS, INC. | 240,616 | $126.0M |
| MOHMolina Healthcare Inc | 924,261 | $123.2M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 1,836,433 | $115.1M |
| TERNTerns Pharmaceuticals, Inc. | 2,135,271 | $112.6M |
| SNYSanofi | 2,331,969 | $112.4M |
| OSCROscar Health Inc. | 9,652,604 | $110.7M |
| CORCencora Inc. | 347,364 | $109.1M |
| XENEXenon Pharmaceuticals Inc. | 1,695,037 | $98.6M |
| IONSIONIS PHARMACEUTICALS INC | 1,222,459 | $91.8M |
| DVADaVita Inc. | 593,010 | $91.1M |
| SRPTSarepta Therapeutics, Inc. | 3,818,732 | $83.1M |
| CRSPCRISPR Therapeutics AG | 1,647,106 | $78.4M |
| BAXBaxter International Inc. | 4,633,176 | $77.8M |
| AXSMAxsome Therapeutics, Inc. | 444,598 | $75.1M |
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| BNTXBioNTech SE | 763,661 | $67.9M |
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| BMRNBIOMARIN PHARMACEUTICAL INC | 1,173,113 | $66.3M |
| TGTXTG THERAPEUTICS, INC. | 1,992,420 | $66.2M |
| ACLXArcellx, Inc. | 572,101 | $65.7M |
| NKTRNEKTAR THERAPEUTICS | 903,190 | $65.0M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 1,170,848 | $64.6M |
| LQDALiquidia Corp | 1,657,581 | $62.6M |
| TLRYTilray Brands, Inc. | 9,239,532 | $59.8M |
| QUREuniQure N.V. | 3,644,200 | $59.6M |
| GHGuardant Health Inc. | 582,289 | $53.8M |
| AGIOAGIOS PHARMACEUTICALS, INC. | 1,556,353 | $52.7M |
| SLNOSOLENO THERAPEUTICS INC | 1,567,977 | $52.5M |
| IDXXIDEXX LABORATORIES INC /DE | 85,061 | $47.8M |
| PRAXPraxis Precision Medicines, Inc. | 144,117 | $46.4M |
| SMMTSummit Therapeutics Inc. | 2,410,733 | $45.7M |
| JAZZJazz Pharmaceuticals plc | 237,214 | $44.8M |
| PCVXVaxcyte, Inc. | 757,773 | $44.0M |
| KRYSKrystal Biotech, Inc. | 164,842 | $42.6M |
| DGXQuest Diagnostics Incorporated | 216,019 | $42.3M |
| VTRSViatris Inc | 3,109,017 | $42.0M |
| CAPRCAPRICOR THERAPEUTICS, INC. | 1,365,075 | $41.5M |
| MLYSMineralys Therapeutics, Inc. | 1,434,270 | $38.9M |
| SLSSELLAS Life Sciences Group, Inc. | 8,981,556 | $38.0M |
| VCELVericel Corp | 1,172,800 | $37.7M |
| CORTCORCEPT THERAPEUTICS INC | 905,831 | $36.5M |
| SUNSUNSET ISLAND GROUP | 560,804 | $36.4M |
| ONCBeOne Medicines Ltd. | 119,608 | $35.5M |
| NBIXNEUROCRINE BIOSCIENCES INC | 266,927 | $35.2M |
| WSTWest Pharmaceutical Services Inc. | 138,526 | $34.7M |
| NTLAIntellia Therapeutics, Inc. | 2,702,665 | $34.6M |
| TVTXTravere Therapeutics, Inc. | 1,093,858 | $32.5M |
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| ACHCAcadia Healthcare Company Inc. | 1,328,602 | $31.1M |
| COGTCogent Biosciences, Inc. | 803,878 | $30.9M |
| IMVTImmunovant, Inc. | 1,218,107 | $30.3M |
| BCRXBIOCRYST PHARMACEUTICALS INC | 3,151,704 | $30.0M |
| ICLRICON plc | 267,331 | $29.6M |
| CGONCG Oncology, Inc. | 432,703 | $29.3M |
| QGENQIAGEN N.V. | 716,000 | $28.7M |
| ADMAADMA BIOLOGICS, INC. | 3,152,304 | $28.4M |
| APGEApogee Therapeutics, Inc. | 318,399 | $26.8M |
| IQVIQVIA Holdings Inc. | 157,081 | $26.8M |
| NVAXNOVAVAX INC | 3,262,842 | $26.6M |
| RXRXRECURSION PHARMACEUTICALS, INC. | 8,385,877 | $25.7M |
| RGENREPLIGEN CORP | 213,276 | $25.1M |
| PTCTPTC THERAPEUTICS, INC. | 362,938 | $24.7M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 287,201 | $24.1M |
| PVLAPALVELLA THERAPEUTICS, INC. | 192,908 | $24.0M |
| ERASErasca, Inc. | 1,478,547 | $23.9M |
| CPRXCATALYST PHARMACEUTICALS, INC. | 962,320 | $23.8M |
| RAREUltragenyx Pharmaceutical Inc. | 1,135,798 | $23.8M |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 6,698,143 | $23.5M |
| ROIVRoivant Sciences Ltd. | 843,995 | $23.4M |
| MLTXMoonLake Immunotherapeutics | 1,208,624 | $22.5M |
| PTGXProtagonist Therapeutics, Inc | 211,576 | $22.3M |
| DFTXDefinium Therapeutics Inc. | 1,137,656 | $21.5M |
| ATAIAtai Beckley N.V. | 6,000,126 | $21.2M |
| INCYIncyte Corp. | 219,574 | $20.7M |
| LNTHLantheus Holdings, Inc. | 269,085 | $20.4M |
| DAWNDay One Biopharmaceuticals, Inc. | 906,043 | $19.4M |
| KNSAKiniksa Pharmaceuticals International, plc | 402,611 | $19.4M |
| PBIPROVENTION BIO, INC. | 1,734,546 | $19.2M |
| ZBHZimmer Biomet Holdings Inc. | 209,527 | $18.9M |
| HLFHerbalife Ltd. | 1,280,247 | $18.8M |
| CMPSCOMPASS Pathways plc | 3,387,888 | $18.7M |
| GPCRStructure Therapeutics Inc. | 380,042 | $18.3M |
| INSPInspire Medical Systems Inc. | 353,773 | $18.2M |
| OLMAOlema Pharmaceuticals, Inc. | 1,207,382 | $18.0M |
| REPLReplimune Group, Inc. | 2,320,879 | $17.8M |
| CRLCHARLES RIVER LABORATORIES INTERNATIONAL, INC. | 100,095 | $17.3M |
| ALKSAlkermes plc. | 446,595 | $15.8M |
| HALOHALOZYME THERAPEUTICS, INC. | 241,886 | $15.6M |
| PRGOPERRIGO Co plc | 1,455,564 | $15.6M |
| INDVIndivior Pharmaceuticals, Inc. | 505,297 | $15.4M |
| OGNOrganon & Co. | 2,551,660 | $15.3M |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 465,425 | $14.9M |
| SRRKScholar Rock Holding Corp | 303,036 | $14.9M |
| OMEROMEROS CORP | 1,404,130 | $14.8M |
| CTMXCytomX Therapeutics, Inc. | 3,079,915 | $14.5M |
| ANROAlto Neuroscience, Inc. | 637,598 | $14.3M |
| GLPGGalapagos NV | 462,687 | $13.9M |
| RNAAtrium Therapeutics Inc. | 1,030,143 | $13.8M |
| BEAMBeam Therapeutics Inc. | 556,591 | $13.3M |
| BHVNBiohaven Ltd. | 1,548,667 | $13.1M |
| CRMDCorMedix Inc. | 1,894,810 | $12.9M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 147,184 | $12.8M |
| RPRXRoyalty Pharma plc | 263,533 | $12.6M |
| VERAVera Therapeutics, Inc. | 308,120 | $12.4M |
| BHCBausch Health Companies Inc. | 2,284,287 | $12.3M |
| CNTACentessa Pharmaceuticals plc | 309,937 | $12.3M |
| MEDPMedpace Holdings Inc. | 25,378 | $12.2M |
| MIRMMirum Pharmaceuticals, Inc. | 128,117 | $11.8M |
| ALMSALUMIS INC. | 526,555 | $11.6M |
| CRVSCorvus Pharmaceuticals, Inc. | 768,436 | $11.2M |
| KYMRKymera Therapeutics, Inc. | 134,003 | $11.2M |
| PRCTPROCEPT BioRobotics Corporation | 443,401 | $11.1M |
| SNDXSyndax Pharmaceuticals Inc | 472,121 | $11.0M |
| FRMMFORUM MARKETS Inc | 3,815,200 | $11.0M |
| MESOMesoblast Limited | 714,572 | $11.0M |
| TBPHTheravance Biopharma, Inc. | 667,879 | $10.8M |
| TWSTTwist Bioscience Corp | 227,719 | $10.8M |
| ARRYARRAY BIOPHARMA INC | 1,463,713 | $10.6M |
| INBXInhibrx Biosciences, Inc. | 157,373 | $10.6M |
| TECHBIO-TECHNE Corp | 195,529 | $10.2M |
| JANXJanux Therapeutics, Inc. | 727,355 | $10.1M |
| ELANElanco Animal Health Inc | 414,608 | $9.9M |
| FOLDAMICUS THERAPEUTICS, INC. | 666,941 | $9.6M |
| AVTXAvalo Therapeutics, Inc. | 637,200 | $9.5M |
| RLMDRELMADA THERAPEUTICS, INC. | 1,340,172 | $9.3M |
| KODKodiak Sciences Inc. | 242,827 | $9.3M |
| TECXTectonic Therapeutic, Inc. | 293,475 | $9.1M |
| VRDNViridian Therapeutics, Inc.\DE | 461,677 | $9.0M |
| CLOVClover Health Investments Corp. | 5,091,057 | $9.0M |
| ALHCAlignment Healthcare Inc. | 504,867 | $8.9M |
| IDYAIDEAYA Biosciences, Inc. | 252,009 | $8.4M |
| GMEDGlobus Medical Inc. | 96,303 | $8.3M |
| ELVNEnliven Therapeutics, Inc. | 206,572 | $8.1M |
| IMNMImmunome Inc. | 359,885 | $7.9M |
| NEOGNEOGEN CORP | 839,255 | $7.8M |
| ARDXARDELYX, INC. | 1,281,768 | $7.7M |
| ABCLAbCellera Biologics Inc. | 2,195,593 | $7.7M |
| ALTAltimmune, Inc. | 2,442,356 | $7.5M |
| KPTIKaryopharm Therapeutics Inc. | 1,315,038 | $7.3M |
| VORVor Biopharma Inc. | 408,808 | $7.3M |
| WVEWave Life Sciences Ltd. | 999,625 | $7.2M |
| ZYMEZymeworks Inc. | 274,921 | $6.9M |
| CYRXCryoport, Inc. | 823,135 | $6.8M |
| TRVITrevi Therapeutics, Inc. | 566,088 | $6.8M |
| AQSTAquestive Therapeutics, Inc. | 1,615,435 | $6.7M |
| IRWDIRONWOOD PHARMACEUTICALS INC | 1,900,757 | $6.7M |
| OCULOCULAR THERAPEUTIX, INC | 775,544 | $6.6M |
| ZVRAZEVRA THERAPEUTICS, INC. | 704,782 | $6.6M |
| LGNDLigand Pharmaceuticals Incorporated | 32,603 | $6.5M |
| SYRESpyre Therapeutics, Inc. | 128,462 | $6.5M |
| ARQTArcutis Biotherapeutics, Inc. | 265,779 | $6.3M |
| LYELLyell Immunopharma, Inc. | 310,198 | $6.2M |
| SDGRSchrodinger, Inc. | 533,915 | $6.1M |
| LEGNLegend Biotech Corp | 331,864 | $6.0M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 113,250 | $5.9M |
| CAICaris Life Sciences Inc. | 322,766 | $5.8M |
| URGNUroGen Pharma Ltd. | 317,423 | $5.7M |
| ANIPANI PHARMACEUTICALS INC | 71,314 | $5.5M |
| KYTXKyverna Therapeutics, Inc. | 633,400 | $5.5M |
| CRONCronos Group Inc. | 2,169,367 | $5.4M |
| ACADACADIA PHARMACEUTICALS INC | 242,692 | $5.4M |
| IMMXImmix Biopharma, Inc. | 588,794 | $5.4M |
| ZBIOZenas BioPharma, Inc. | 266,005 | $5.2M |
| PHATPhathom Pharmaceuticals, Inc. | 458,079 | $5.1M |
| SNDLSNDL Inc. | 3,854,921 | $5.1M |
| OCGNOcugen, Inc. | 2,810,649 | $5.1M |
| ABEOABEONA THERAPEUTICS INC. | 1,108,670 | $5.0M |
| FBRXForte Biosciences, Inc. | 190,794 | $4.9M |
| AMLXAmylyx Pharmaceuticals, Inc. | 354,002 | $4.9M |
| OVIDOvid Therapeutics Inc. | 2,171,094 | $4.8M |
| NRIXNurix Therapeutics, Inc. | 309,855 | $4.8M |
| AVXLANAVEX LIFE SCIENCES CORP. | 1,539,563 | $4.7M |
| EWTXEdgewise Therapeutics, Inc. | 149,574 | $4.7M |
| ESPREsperion Therapeutics, Inc. | 1,715,005 | $4.7M |
| PRMEPrime Medicine, Inc. | 1,349,829 | $4.7M |
| RCUSArcus Biosciences, Inc. | 216,471 | $4.7M |
| HRMYHarmony Biosciences Holdings, Inc. | 163,901 | $4.6M |
| NEONeoGenomics Inc. | 618,652 | $4.6M |
| ETONEton Pharmaceuticals, Inc. | 179,784 | $4.4M |
| AVBPArriVent BioPharma, Inc. | 190,698 | $4.4M |
| IRONDisc Medicine, Inc. | 68,306 | $4.4M |
| LXRXLEXICON PHARMACEUTICALS, INC. | 2,766,264 | $4.3M |
| MNKDMANNKIND CORP | 1,743,262 | $4.3M |
| CRNXCrinetics Pharmaceuticals, Inc. | 117,153 | $4.3M |
| DYNDyne Therapeutics, Inc. | 234,424 | $4.3M |
| SLDBSolid Biosciences Inc. | 575,831 | $4.1M |
| IRDOpus Genetics, Inc. | 904,783 | $4.1M |
| CLPTClearPoint Neuro Inc. | 451,484 | $4.1M |
| ELTXElicio Therapeutics, Inc. | 373,804 | $4.0M |
| ABSIAbsci Corporation | 1,327,078 | $4.0M |
| PGENPRECIGEN, INC. | 1,027,511 | $4.0M |
| UNCYUnicycive Therapeutics, Inc. | 598,319 | $3.9M |
| TARSTarsus Pharmaceuticals, Inc. | 56,035 | $3.9M |
| CRBPCorbus Pharmaceuticals Holdings, Inc. | 418,315 | $3.9M |
| CBIOCRESCENT BIOPHARMA, INC. | 213,635 | $3.9M |
| MAZEMaze Therapeutics, Inc. | 128,001 | $3.8M |
| NUVLNuvalent, Inc. | 36,753 | $3.8M |
| AUPHAurinia Pharmaceuticals Inc. | 253,337 | $3.8M |
| STOKStoke Therapeutics, Inc. | 113,891 | $3.7M |
| DNLIDenali Therapeutics Inc. | 191,475 | $3.7M |
| CCCCC4 Therapeutics, Inc. | 1,394,440 | $3.7M |
| CLDXCelldex Therapeutics, Inc. | 115,448 | $3.7M |
| VIRVir Biotechnology, Inc. | 402,261 | $3.6M |
| ARCTArcturus Therapeutics Holdings Inc. | 463,414 | $3.6M |
| CGEMCullinan Therapeutics, Inc. | 249,277 | $3.5M |
| XFORX4 Pharmaceuticals, Inc | 856,222 | $3.5M |
| GERNGERON CORP | 2,364,617 | $3.5M |
| RGNXREGENXBIO Inc. | 414,984 | $3.5M |
| ASRTAssertio Holdings, Inc. | 181,600 | $3.5M |
| ORKAOruka Therapeutics, Inc. | 70,184 | $3.4M |
| TNGXTango Therapeutics, Inc. | 161,050 | $3.4M |
| RZLTRezolute, Inc. | 1,087,489 | $3.3M |
| KALVKalVista Pharmaceuticals, Inc. | 160,360 | $3.2M |
| CLYMClimb Bio, Inc. | 459,203 | $3.1M |
| IVVDInvivyd, Inc. | 2,413,613 | $3.1M |
| ICUIICU Medical Inc. | 24,156 | $3.1M |
| NGNENeurogene Inc. | 153,200 | $3.1M |
| MBXMBX Biosciences, Inc. | 102,387 | $3.1M |
| STROSUTRO BIOPHARMA, INC. | 121,502 | $3.0M |
| CABACabaletta Bio, Inc. | 1,116,100 | $3.0M |
| GALTGALECTIN THERAPEUTICS INC | 1,073,202 | $3.0M |
| CNTXContext Therapeutics Inc. | 1,093,894 | $2.9M |
| GMABGenmab A/S | 106,800 | $2.9M |
| ADPTAdaptive Biotechnologies Corp | 202,317 | $2.8M |
| MBOTMicrobot Medical Inc. | 1,140,707 | $2.7M |
| ZLABZai Lab Ltd | 145,448 | $2.7M |
| ALXOALX ONCOLOGY HOLDINGS INC | 1,362,707 | $2.7M |
| RIGLRIGEL PHARMACEUTICALS INC | 99,590 | $2.7M |
| ABUSArbutus Biopharma Corp | 598,070 | $2.7M |
| PBHPrestige Consumer Healthcare Inc. | 44,962 | $2.7M |
| TYRATyra Biosciences, Inc. | 68,243 | $2.6M |
| CGCCanopy Growth Corp | 2,720,976 | $2.6M |
| XERSXeris Biopharma Holdings, Inc. | 443,171 | $2.6M |
| FULCFulcrum Therapeutics, Inc. | 335,036 | $2.6M |
| ANNXAnnexon, Inc. | 457,540 | $2.5M |
| DNAGinkgo Bioworks Holdings Inc. | 412,236 | $2.5M |
| KURAKura Oncology, Inc. | 305,392 | $2.5M |
| PHVSPharvaris N.V. | 86,774 | $2.5M |
| BIOABioAge Labs, Inc. | 137,789 | $2.4M |
| GLUEMonte Rosa Therapeutics, Inc. | 145,751 | $2.4M |
| HELPCYBIN INC. | 498,325 | $2.4M |
| LENZLENZ Therapeutics, Inc. | 259,404 | $2.4M |
| BCAXBicara Therapeutics Inc. | 118,544 | $2.4M |
| NUVBNuvation Bio Inc. | 539,613 | $2.3M |
| KRROKorro Bio, Inc. | 204,100 | $2.3M |
| FMSFresenius Medical Care AG American Depositary Shares (Each representing 1/2 of an Ordinary Share) | 100,892 | $2.3M |
| ACRSAclaris Therapeutics, Inc. | 600,430 | $2.3M |
| LCTXLineage Cell Therapeutics, Inc. | 1,406,285 | $2.2M |
| ANABANAPTYSBIO, INC | 39,577 | $2.2M |
| LRMRLarimar Therapeutics, Inc. | 487,660 | $2.2M |
| TNXPTonix Pharmaceuticals Holding Corp. | 157,979 | $2.2M |
| EBSEmergent BioSolutions Inc. | 260,239 | $2.2M |
| CMPXCompass Therapeutics, Inc. | 391,725 | $2.1M |
| CADLCandel Therapeutics, Inc. | 420,273 | $2.1M |
| SPRYARS Pharmaceuticals, Inc. | 255,737 | $2.1M |
| VSTMVerastem, Inc. | 384,960 | $2.0M |
| MCRBSeres Therapeutics, Inc. | 226,939 | $2.0M |
| CRBUCaribou Biosciences, Inc. | 1,047,203 | $2.0M |
| RCKTRocket Pharmaceuticals Inc. | 553,639 | $2.0M |
| SANASana Biotechnology, Inc. | 685,855 | $2.0M |
| FDMT4D Molecular Therapeutics, Inc. | 208,028 | $1.9M |
| ARVNARVINAS, INC. | 179,353 | $1.9M |
| ZURAZura Bio Ltd | 312,786 | $1.9M |
| RGCRegencell Bioscience Holdings Ltd | 72,700 | $1.8M |
| PRTAPROTHENA CORP PUBLIC LTD CO | 183,892 | $1.8M |
| SEPNSepterna, Inc. | 73,000 | $1.8M |
| IMRXImmuneering Corp | 325,907 | $1.7M |
| SGMTSagimet Biosciences Inc. | 323,004 | $1.7M |
| ABOSAcumen Pharmaceuticals, Inc. | 713,376 | $1.7M |
| MRVIMARAVAI LIFESCIENCES HOLDINGS, INC. | 587,439 | $1.7M |
| ACBAURORA CANNABIS INC | 506,900 | $1.7M |
| PGNYProgyny Inc. | 97,174 | $1.7M |
| FLGTFulgent Genetics Inc. | 102,078 | $1.6M |
| MMSIMerit Medical Systems Inc. | 23,305 | $1.6M |
| PEPGPepGen Inc. | 887,468 | $1.6M |
| PCRXPacira BioSciences, Inc. | 69,483 | $1.6M |
| AKBAAkebia Therapeutics, Inc. | 1,105,119 | $1.5M |
| QDELQuidelOrtho Corp | 92,058 | $1.5M |
| ACHVACHIEVE LIFE SCIENCES, INC. | 510,883 | $1.5M |
| KZRKezar Life Sciences, Inc. | 201,600 | $1.5M |
| MGNXMACROGENICS INC | 512,827 | $1.5M |
| CAMPCamp4 Therapeutics Corp | 336,047 | $1.5M |
| PAHCPHIBRO ANIMAL HEALTH CORP | 26,598 | $1.5M |
| RLAYRelay Therapeutics, Inc. | 147,158 | $1.5M |
| INVAInnoviva, Inc. | 62,714 | $1.5M |
| MYGNMYRIAD GENETICS INC | 323,519 | $1.5M |
| PLSEPulse Biosciences Inc Common Stock (DE) | 67,411 | $1.5M |
| BVSBioventus Inc. | 158,317 | $1.4M |
| ZNTLZentalis Pharmaceuticals, Inc. | 616,557 | $1.4M |
| ACHAccendra Health Inc. | 632,310 | $1.4M |
| FBIOFortress Biotech Inc. | 506,645 | $1.4M |
| RAPPRapport Therapeutics, Inc. | 44,672 | $1.4M |
| AMRNAMARIN CORP PLCUK | 95,767 | $1.4M |
| BCYCBICYCLE THERAPEUTICS PLC | 296,788 | $1.4M |
| KROSKeros Therapeutics, Inc. | 119,042 | $1.3M |
| BMEABiomea Fusion, Inc. | 856,665 | $1.3M |
| MDWDMediWound Ltd. | 80,400 | $1.3M |
| FLNAFilana Therapeutics Inc. | 749,178 | $1.3M |
| UPXIUPEXI, INC. | 1,260,528 | $1.2M |
| ANVSAnnovis Bio, Inc. | 541,036 | $1.2M |
| ORICOric Pharmaceuticals, Inc. | 94,355 | $1.2M |
| TAKTakeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock) | 63,624 | $1.2M |
| ALTSALT5 Sigma Corp | 999,016 | $1.1M |
| TSHATaysha Gene Therapies, Inc. | 245,097 | $1.1M |
| AGLagilon health inc. | 137,170 | $1.1M |
| HUMAHumacyte Inc. | 1,757,548 | $1.1M |
| JBIOJade Biosciences, Inc. | 75,908 | $1.1M |
| CATXPerspective Therapeutics, Inc. | 252,930 | $1.1M |
| ALDXAldeyra Therapeutics, Inc. | 622,342 | $1.1M |
| RANIRani Therapeutics Holdings, Inc. | 1,437,822 | $1.1M |
| IMCRImmunocore Holdings plc | 34,122 | $1.0M |
| PRLDPrelude Therapeutics Inc | 288,788 | $988K |
| ALLOAllogene Therapeutics, Inc. | 404,760 | $988K |
| CYPHCYPHERPUNK TECHNOLOGIES INC. | 1,217,553 | $963K |
| ASMBASSEMBLY BIOSCIENCES, INC. | 32,949 | $914K |
| GANXGain Therapeutics, Inc. | 469,567 | $911K |
| TARAProtara Therapeutics, Inc. | 172,726 | $900K |
| SPROSpero Therapeutics, Inc. | 381,615 | $893K |
| EDITEditas Medicine, Inc. | 360,705 | $891K |
| ATYRaTYR PHARMA INC | 1,132,344 | $883K |
| AVIRAtea Pharmaceuticals, Inc. | 159,535 | $858K |
| CNTBConnect Biopharma Holdings Ltd | 324,108 | $849K |
| COLLCOLLEGIUM PHARMACEUTICAL, INC | 25,157 | $832K |
| AURAAura Biosciences, Inc. | 123,983 | $829K |
| NVCTNuvectis Pharma, Inc. | 105,286 | $814K |
| SLNSilence Therapeutics Plc | 154,381 | $814K |
| INOINOVIO PHARMACEUTICALS, INC. | 460,662 | $802K |
| EOLSEvolus, Inc. | 191,409 | $787K |
| IBIOiBio, Inc. | 412,725 | $784K |
| GRFSGrifols S.A. | 94,400 | $757K |
| XOMAXOMA Royalty Corporation | 23,990 | $753K |
| MISTMilestone Pharmaceuticals Inc. | 629,146 | $749K |
| SHCSotera Health Company | 50,965 | $731K |
| NERVMinerva Neurosciences, Inc. | 119,131 | $718K |
| SVRASavara Inc | 130,699 | $714K |
| WHWKWhitehawk Therapeutics, Inc. | 203,465 | $702K |
| CHRSCoherus Oncology, Inc. | 414,800 | $701K |
| CRDFCardiff Oncology, Inc. | 424,559 | $688K |
| SGMOSANGAMO THERAPEUTICS, INC | 2,752,363 | $683K |
| ARMPArmata Pharmaceuticals, Inc. | 64,759 | $663K |
| NTHINEONC TECHNOLOGIES HOLDINGS, INC. | 91,036 | $638K |
| MDXGMiMedx Group Inc | 161,415 | $638K |
| PLXProtalix BioTherapeutics, Inc. | 285,385 | $619K |
| HYFTMindWalk Holdings Corp. | 544,916 | $616K |
| MDXHMDxHealth SA | 267,692 | $616K |
| AUTLAutolus Therapeutics plc | 442,943 | $611K |
| KYNBKYNTRA BIO INC. | 89,400 | $606K |
| DRTSAlpha Tau Medical Ltd. | 83,438 | $590K |
| RDYDR REDDYS LABORATORIES LTD | 42,300 | $586K |
| ALECAlector, Inc. | 269,297 | $579K |
| LFVNLifevantage Corp | 131,200 | $567K |
| NRCNational Research Corporation Common Stock (Delaware) | 33,313 | $566K |
| UPBUpstream Bio, Inc. | 61,961 | $558K |
| BDSXBiodesix Inc. | 37,890 | $549K |
| TRDAEntrada Therapeutics, Inc. | 43,415 | $548K |
| GOSSGossamer Bio, Inc. | 1,588,873 | $524K |
| GRCEGrace Therapeutics, Inc. | 112,800 | $522K |
| IPSCCentury Therapeutics, Inc. | 226,687 | $512K |
| PBYIPUMA BIOTECHNOLOGY, INC. | 79,689 | $509K |
| DTILPRECISION BIOSCIENCES INC | 84,862 | $467K |
| ORMPORAMED PHARMACEUTICALS INC. | 136,218 | $463K |
| EQEquillium, Inc. | 231,035 | $462K |
| CSTLCastle Biosciences Inc. | 18,820 | $462K |
| ANIKAnika Therapeutics Inc. | 31,751 | $460K |
| ENTAENANTA PHARMACEUTICALS INC | 36,408 | $460K |
| FATEFATE THERAPEUTICS INC | 380,496 | $457K |
| MGTXMeiraGTx Holdings plc | 52,714 | $457K |
| AGENAGENUS INC | 134,759 | $450K |
| OPKOPKO HEALTH, INC. | 391,516 | $446K |
| VYGRVoyager Therapeutics, Inc. | 114,291 | $441K |
| ACIUAC Immune SA | 157,762 | $434K |
| OBIOOrchestra BioMed Holdings Inc. | 97,521 | $414K |
| RVPHREVIVA PHARMACEUTICALS HOLDINGS, INC. | 527,800 | $385K |
| PROKPROKIDNEY CORP. | 204,488 | $366K |
| ACETAdicet Bio, Inc. | 52,900 | $360K |
| ADCTADC Therapeutics SA | 94,468 | $354K |
| NAGENiagen Bioscience, Inc. | 80,072 | $353K |
| ANIXAnixa Biosciences Inc | 133,668 | $345K |
| ELDNEledon Pharmaceuticals, Inc. | 109,949 | $339K |
| XNCRXencor Inc | 28,039 | $338K |
| NPCENeuropace Inc. | 25,180 | $331K |
| KLRSKalaris Therapeutics, Inc. | 52,684 | $304K |
| TNYATenaya Therapeutics, Inc. | 432,772 | $299K |
| CMIIUColumbus Circle Capital Corp II Unit | 30,000 | $298K |
| NUSNu Skin Enterprises Inc. | 40,909 | $298K |
| SIONSionna Therapeutics, Inc. | 7,310 | $293K |
| ATOSATOSSA THERAPEUTICS, INC. | 55,000 | $289K |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 360,253 | $288K |
| AMPHAmphastar Pharmaceuticals, Inc. | 14,601 | $286K |
| INMBInmune Bio, Inc. | 243,191 | $275K |
| OGIORGANIGRAM GLOBAL INC. | 202,753 | $272K |
| VMDViemed Healthcare Inc. | 28,489 | $262K |
| AVNSAvanos Medical Inc. | 18,512 | $259K |
| DMRADamora Therapeutics, Inc. | 9,770 | $253K |
| NKTXNkarta, Inc. | 119,376 | $252K |
| BDTXBlack Diamond Therapeutics, Inc. | 117,158 | $250K |
| NATRNATURES SUNSHINE PRODUCTS INC | 10,302 | $247K |
| CPIXCUMBERLAND PHARMACEUTICALS INC | 73,500 | $239K |
| LFCRLIFECORE BIOMEDICAL, INC. DE | 63,789 | $237K |
| PLRXPLIANT THERAPEUTICS, INC. | 187,156 | $236K |
| DRUGBRIGHT MINDS BIOSCIENCES INC. | 3,141 | $229K |
| MNPRMonopar Therapeutics | 4,137 | $227K |
| NRXPNRX Pharmaceuticals Inc. | 102,200 | $218K |
| DMACDiaMedica Therapeutics Inc. | 31,950 | $216K |
| PPBTPURPLE BIOTECH LTD. | 53,403 | $216K |
| CLLSCellectis S.A. | 65,942 | $209K |
| STIMNeuronetics Inc. | 138,581 | $201K |
| LPCNLipocine Inc. | 24,908 | $199K |
| VIVOMERIDIAN BIOSCIENCE INC | 83,219 | $191K |
| IMDXInsight Molecular Diagnostics Inc. | 56,093 | $184K |
| SABSSAB BIOTHERAPEUTICS, INC. | 45,900 | $176K |
| OFIXOrthofix Medical Inc. Common Stock (DE) | 13,847 | $159K |
| TCRXTScan Therapeutics, Inc. | 157,228 | $159K |
| GHRSGH Research PLC | 11,200 | $157K |
| COYACoya Therapeutics, Inc. | 39,316 | $155K |
| GNLXGENELUX Corp | 61,980 | $150K |
| MREOMereo BioPharma Group plc | 443,920 | $146K |
| INNVINNOVUS PHARMACEUTICALS, INC. | 18,047 | $145K |
| FENCFENNEC PHARMACEUTICALS INC. | 22,400 | $138K |
| CGENCOMPUGEN LTD | 64,364 | $137K |
| BBNXBeta Bionics Inc. | 13,428 | $135K |
| SIGASIGA TECHNOLOGIES INC | 24,767 | $133K |
| BNTCBenitec Biopharma Inc. | 11,908 | $127K |
| ATNMActinium Pharmaceuticals, Inc. | 123,998 | $123K |
| PYXSPyxis Oncology, Inc. | 83,501 | $122K |
| LUCDLucid Diagnostics Inc. | 103,174 | $119K |
| SRTSSensus Healthcare Inc. | 26,300 | $105K |
| VTGNVistagen Therapeutics, Inc. | 183,007 | $105K |
| CRDLCardiol Therapeutics Inc. | 70,396 | $95K |
| NNVCNANOVIRICIDES, INC. | 99,031 | $90K |
| KRMDKORU Medical Systems Inc. Common Stock (DE) | 18,933 | $82K |
| GUTSFractyl Health Inc. | 176,087 | $81K |
| RCELAvita Medical Inc. | 19,700 | $73K |
| TLPHTALPHERA, INC. | 96,916 | $73K |
| BHSTBIOHARVEST SCIENCES INC. | 16,394 | $71K |
| IFRXInflaRx N.V. | 77,114 | $69K |
| ORGOOrganogenesis Holdings Inc. | 28,307 | $67K |
| OABIOmniAb Inc. | 41,629 | $65K |
| SOPHSOPHiA GENETICS SA | 13,156 | $65K |
| MRKRMarker Therapeutics, Inc. | 48,780 | $63K |
| CGTXCOGNITION THERAPEUTICS INC | 80,663 | $61K |
| MNOVMEDICINOVA INC | 43,926 | $60K |
| DERMJourney Medical Corp | 12,721 | $60K |
| IKTInhibikase Therapeutics, Inc. | 35,100 | $59K |
| LSTALISATA THERAPEUTICS, INC. | 11,604 | $58K |
| FHTXFoghorn Therapeutics Inc. | 11,637 | $56K |
| HURATuHURA Biosciences, Inc./NV | 30,847 | $55K |
| TLSITriSalus Life Sciences Inc. | 12,994 | $52K |
| VERUVERU INC. | 22,971 | $51K |
| BCDABioCardia, Inc. | 38,827 | $47K |
| TXMDTherapeuticsMD, Inc. | 21,220 | $43K |
| PRQRProQR Therapeutics N.V. | 25,906 | $42K |
| TLSATiziana Life Sciences Ltd | 31,967 | $37K |
| SKINThe Beauty Health Company | 41,704 | $37K |
| OTLKOutlook Therapeutics, Inc. | 176,884 | $37K |
| BYSIBeyondSpring Inc. | 22,300 | $37K |
| CCELCryo-Cell International Inc. | 10,018 | $36K |
| VYNEVYNE Therapeutics Inc. | 57,784 | $35K |
| CTXRCitius Pharmaceuticals, Inc. | 36,838 | $33K |
| LITSLite Strategy, Inc. | 27,834 | $32K |
| IGCIGC Pharma, Inc. | 122,595 | $32K |
| NBPNovaBridge Biosciences | 12,817 | $32K |
| BFRIBiofrontera Inc. | 38,574 | $31K |
| DAREDare Bioscience, Inc. | 17,130 | $31K |
| MXCTMaxCyte Inc. | 41,584 | $29K |
| RFLRafael Holdings, Inc. | 23,278 | $29K |
| MIRAMIRA PHARMACEUTICALS, INC. | 25,146 | $27K |
| SCYXSCYNEXIS INC | 27,807 | $25K |
| BLRXBioLineRx Ltd. | 10,200 | $24K |
| COCHEnvoy Medical Inc. | 35,297 | $23K |
| TMCITreace Medical Concepts Inc. | 17,049 | $23K |
| SILOSilo Pharma, Inc. | 62,795 | $23K |
| CELZCREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. | 10,469 | $22K |
| DYAIDYADIC INTERNATIONAL INC | 25,925 | $21K |
| CMMBChemomab Therapeutics Ltd. | 13,491 | $21K |
| CALCCalciMedica, Inc. | 30,716 | $17K |
| BTMDbiote Corp. | 10,932 | $15K |
| APMAptorum Group Ltd | 16,777 | $13K |
| PDSBPDS Biotechnology Corp | 22,052 | $13K |
| NOTVInotiv, Inc. | 41,432 | $11K |
| APREAprea Therapeutics, Inc. | 13,018 | $10K |
| JSPRJasper Therapeutics Inc. | 11,149 | $10K |
| ENLVEnlivex Ltd. | 10,314 | $10K |
| QUCYMainz Biomed N.V. | 18,517 | $9K |
| TRIBTRINITY BIOTECH PLC | 14,300 | $8K |
| MTNBMatinas BioPharma Holdings, Inc. | 14,328 | $7K |
| COSMCosmos Health Inc. | 17,734 | $6K |
| IMMPImmutep Limited | 12,800 | $4K |