| INSMINSMED Inc | 4,842,880 | $791.9M |
| PTGXProtagonist Therapeutics, Inc | 5,059,053 | $533.2M |
| PTCTPTC THERAPEUTICS, INC. | 7,746,415 | $527.8M |
| ARGXARGENX SE | 709,446 | $518.1M |
| TNGXTango Therapeutics, Inc. | 13,300,620 | $278.2M |
| APGEApogee Therapeutics, Inc. | 2,782,097 | $234.2M |
| SYRESpyre Therapeutics, Inc. | 4,171,996 | $210.4M |
| COGTCogent Biosciences, Inc. | 5,458,675 | $210.1M |
| STOKStoke Therapeutics, Inc. | 5,623,525 | $183.1M |
| CYTKCYTOKINETICS INC | 2,721,158 | $179.4M |
| ACADACADIA PHARMACEUTICALS INC | 7,144,524 | $159.0M |
| APLSApellis Pharmaceuticals, Inc. | 3,685,045 | $148.2M |
| IMCRImmunocore Holdings plc | 4,869,798 | $146.8M |
| IMTXImmatics N.V. | 12,869,340 | $126.6M |
| ORKAOruka Therapeutics, Inc. | 2,058,148 | $101.0M |
| GHRSGH Research PLC | 5,933,815 | $83.4M |
| CNTACentessa Pharmaceuticals plc | 2,054,175 | $81.6M |
| IMVTImmunovant, Inc. | 3,177,849 | $78.9M |
| RCKTRocket Pharmaceuticals Inc. | 17,687,772 | $63.3M |
| CMPSCOMPASS Pathways plc | 10,632,390 | $58.8M |
| KODKodiak Sciences Inc. | 1,487,934 | $56.7M |
| QUREuniQure N.V. | 2,586,356 | $42.3M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 585,682 | $36.7M |
| SVRASavara Inc | 5,952,380 | $32.5M |
| CADLCandel Therapeutics, Inc. | 6,422,018 | $31.5M |
| AQSTAquestive Therapeutics, Inc. | 7,426,471 | $30.8M |
| NGNENeurogene Inc. | 1,362,456 | $27.5M |
| CGEMCullinan Therapeutics, Inc. | 1,705,960 | $24.2M |
| CMPXCompass Therapeutics, Inc. | 4,186,599 | $22.1M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 248,063 | $20.8M |
| FLGTFulgent Genetics Inc. | 1,289,000 | $20.5M |
| BEAMBeam Therapeutics Inc. | 570,394 | $13.6M |
| AVTXAvalo Therapeutics, Inc. | 856,962 | $12.8M |
| OCGNOcugen, Inc. | 6,666,666 | $12.1M |
| JBIOJade Biosciences, Inc. | 573,205 | $8.1M |
| CAPRCAPRICOR THERAPEUTICS, INC. | 250,000 | $7.6M |
| MISTMilestone Pharmaceuticals Inc. | 6,331,001 | $7.5M |
| KLRSKalaris Therapeutics, Inc. | 1,300,000 | $7.5M |
| IVAInventiva S.A. | 1,298,702 | $7.2M |
| ATAIAtai Beckley N.V. | 2,000,000 | $7.1M |
| CBIOCRESCENT BIOPHARMA, INC. | 372,856 | $6.8M |
| LRMRLarimar Therapeutics, Inc. | 1,500,000 | $6.8M |
| TENXTENAX THERAPEUTICS, INC. | 370,246 | $5.9M |
| DFTXDefinium Therapeutics Inc. | 300,000 | $5.7M |
| FDMT4D Molecular Therapeutics, Inc. | 475,737 | $4.4M |
| IRONDisc Medicine, Inc. | 30,000 | $1.9M |
| IMAImageneBio, Inc. | 334,445 | $1.7M |