OBIONasdaq

Orchestra BioMed Holdings Inc.

Healthcare·Oncology·Phase 3·New Hope, PA, United States
OncologyCardiovascular

Orchestra BioMed Holdings Inc. (OBIO): 4 pipeline candidates · ~12 mo cash runway · 2 clinical trials. Updated within the last hour.

7.5/10

BioSniper Score

5-factor signal · derived from public data

Cash Runway3.4

12.4 months

Financial Health8.6

7% dilution

Pipeline Maturity8.5

Lead: Phase 3

Pipeline Breadth7.2

4 candidates

Catalyst MomentumN/A

N/A

Insider Signal10.0

6 buys · 2 sells (180d)

A transparent, data-derived signal for Orchestra BioMed Holdings Inc.across cash runway, pipeline maturity & breadth, catalyst momentum and clinical/regulatory footprint. Each factor traces to tracked public filings — not an investment recommendation.

Key Financials

Market Cap

$230.5M

Cash

$28.4M

Quarterly Burn

$22.2M

Runway

12.4 mo

Revenue

$110K

Cash Runway vs Catalysts

Tracked catalysts land within the current projected cash runway.

Cash ends ~Jun 2027
Today~14 mo out
Catalyst within runway

Pipeline (4 candidates)

Institutional Holdings

Source: SEC Form 13F · as of Mar 2026

Institutional holders

64

Total value held

$125.0M

HolderSharesValue
perceptive advisors llc10,075,812$42.8M
rtw investments, lp8,306,063$35.3M
vanguard capital management llc4,408,638$18.7M
alyeska investment group, l.p.1,000,000$4.3M
millennium management llc702,543$3.0M
blackrock, inc.635,714$2.7M
geode capital management, llc485,492$2.1M
affinity asset advisors, llc402,550$1.7M
charles schwab investment management inc265,499$1.1M
knott david m jr253,651$1.1M

Showing top 10 of 64 institutional holders of Orchestra BioMed Holdings Inc.. Sign up for the full 13F holder list and quarter-by-quarter ownership history.

2 clinical trials·CEO: Mr. David P. Hochman

Frequently asked questions

How many drug candidates are in Orchestra BioMed Holdings Inc.'s pipeline?

Orchestra BioMed Holdings Inc. (OBIO) has 4 pipeline candidates tracked by BioSniper across SEC filings and clinical trial registrations.

What is Orchestra BioMed Holdings Inc.'s lead drug candidate?

Orchestra BioMed Holdings Inc.'s most advanced tracked candidate is avim therapy (Phase 3) for Hypertension in patients indicated for a cardiac pacemaker.

What is Orchestra BioMed Holdings Inc.'s cash runway?

Based on its most recent reported cash balance and quarterly burn rate, Orchestra BioMed Holdings Inc. has approximately 12.4 months of cash runway.

What is Orchestra BioMed Holdings Inc.'s market capitalization?

Orchestra BioMed Holdings Inc.'s market capitalization is approximately $230.5M.

Who is the CEO of Orchestra BioMed Holdings Inc.?

Mr. David P. Hochman is the chief executive officer of Orchestra BioMed Holdings Inc. (OBIO).

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