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Century Therapeutics, Inc.

Biological products·Phase 1·Philadelphia, PA, United States·CEO: Dr. Brent Pfeiffenberger M.B.A., Pharm.D.
OncologyImmunologyDermatologyNephrology

IPSC evidence brief

What we can confirm

BioSniper Score:
5.2 / 10
Market Cap:
$351.3M

What it means

The company data is ready for cross-source review; unsupported conclusions remain unknown.

What to watch

BioSniper Score: 5.2 / 10 · Market Cap: $351.3M
BioSniper AIPage evidence connected

Prepared research question

What matters most for IPSC—catalysts, financial risk and supporting evidence?

Run cited research

Traceable citations · Unknowns marked

BioSniper AI · IPSC

Century Therapeutics (IPSC) is a publicly traded biotechnology company developing iPSC-derived cell therapies for oncology, autoimmune diseases, and type 1 diabetes, with its most advanced program (CNTY-813) approaching an IND submission in Q4 2026.

Key risk: Capital depletion risk

5.2/10

BioSniper Score

Based on 2 of 6 signals

Limited data coverage

Market Cap

$351.3M

Cash Runway

—

Lead Asset

—

Next Catalyst

—

Financial data as of Jun 30, 2026.

Tracking 3 clinical trials for Century Therapeutics, Inc..

AI OverviewAI overview is shown in English only.

Century Therapeutics (IPSC) is a publicly traded biotechnology company developing iPSC-derived cell therapies for oncology, autoimmune diseases, and type 1 diabetes, with its most advanced program (CNTY-813) approaching an IND submission in Q4 2026.

  • Cash & equivalents of $49.6M as of 2026-06-30 [sec].
  • Net income of -$34.5M for the period ending 2026-06-30 [sec].
  • Shareholders' equity of $232.3M as of 2026-06-30 [sec].
  • CNTY-813, an iPSC-derived islet replacement therapy for type 1 diabetes, completed a pre-IND meeting with the FDA; IND submission on track for Q4 2026 [news · 2026-08-12].
  • CNTY-308, a CD19-targeted CAR-iT cell therapy for B-cell-mediated diseases, is in IND-enabling studies with expected clinical study initiation in 2026 [sec_mda · as of 2026-05-13].

What works

  • Proprietary Allo-Evasion™ 5.0 platform designed to enable immune evasion of iPSC-derived cells, demonstrated in preclinical models for CNTY-813 [sec_mda · as of 2026-08-12].
  • Broad pipeline across multiple cell types (islet cells, T cells, NK cells) from a single iPSC platform, potentially reducing manufacturing complexity [sec_mda · as of 2026-08-12].
  • Scalable GMP manufacturing process established for CNTY-813, with three independent batches from a master cell bank [sec_mda · as of 2026-08-12].

What to weigh

  • No approved products or significant product revenue; company expects to need additional financing to fund operations [sec_mda · as of 2026-08-12].
  • Operating losses expected to increase substantially as preclinical and clinical activities expand [sec_mda · as of 2026-08-12].
  • Cash runway estimated only into Q4 2027 as of November 2025, with no guarantee of meeting that timeline [news · 2025-11-13].
  • All programs are in preclinical or early clinical stages; regulatory and clinical risks remain high [sec_mda · as of 2026-08-12].

From the filings

Quoted directly from source documents.

  • CNTY-813 IND submission on track for Q4 2026

    “IND submission on track for 4Q 2026”

    News · August 12, 2026

  • CNTY-813 preclinical data showed durable glucose control and immune evasion

    “CNTY-813 preclinical data from oral presentation at ADA 2026 showed durable glucose control in vivo, immune evasion, and manufacturing success at clinical scale”

    News · August 12, 2026

  • CNTY-308 is a CD19-targeted CAR-iT cell therapy in IND-enabling studies

    “CNTY-308, a CD19-targeted CD4+/CD8+ ab CAR-iT cell therapy functionally comparable to primary T cells and engineered with Allo-Evasion™ 5.0”

    SEC MD&A · May 13, 2026

Risks & what to watch (3)›

Key risks

  • Capital depletion risk — Cash runway estimated only into Q4 2027; additional financing likely needed [news · 2025-11-13].
  • Preclinical/clinical failure
  • Regulatory delays

What to watch

  • CNTY-813 IND submission in Q4 2026 and initial clinical data expected in H2 2027 [news · 2026-08-12].
  • CNTY-308 clinical study initiation in 2026 [sec_mda · as of 2026-05-13].
  • Cash runway updates and any new financing rounds [news · 2025-11-13].
  • Preclinical data presentations at upcoming conferences (e.g., EASD 2026) [news · 2026-08-12].

Sources: News · SEC filings · SEC MD&A · Generated October 7, 2026 · How we verify sources →

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Evidence & data

Score breakdownBased on 2 of 6 signals · derived from public data

Pipeline inputs are unavailable for this score. It uses only the available signals shown below.

Cash RunwayN/A

Cash runway data unavailable

Financial Health9.6

D/E 0.24 · 0% dilution

Pipeline MaturityN/A

No tracked pipeline phase

Pipeline BreadthN/A

No tracked pipeline candidates

Catalyst MomentumN/A

No upcoming catalysts tracked

Insider Signal0.8

0 buys · 6 sells (180d)

Regulatory

Financials

Short Interest

as of Apr 20, 2026
% of float
6.7%
Days to cover
6.3
Shares short
10,289,543
Daily short volume
-

Short percent of float and days-to-cover reflect reported short positioning. Daily short volume is the exchange-reported short share of a single day's trading volume and is noisier. See the most-shorted biotech ranking →

IPSC short interest

Governance

Frequently asked questions

What is the AI investment thesis for Century Therapeutics, Inc.?

Century Therapeutics (IPSC) is a publicly traded biotechnology company developing iPSC-derived cell therapies for oncology, autoimmune diseases, and type 1 diabetes, with its most advanced program (CNTY-813) approaching an IND submission in Q4 2026.

Who is the CEO of Century Therapeutics, Inc.?

Dr. Brent Pfeiffenberger M.B.A., Pharm.D. is the chief executive officer of Century Therapeutics, Inc. (IPSC).

Where is Century Therapeutics, Inc. headquartered?

Century Therapeutics, Inc. (IPSC) is headquartered in Philadelphia, PA, United States.

What therapeutic areas does Century Therapeutics, Inc. focus on?

Century Therapeutics, Inc. develops therapies across Oncology, Immunology, Dermatology, Nephrology.

923 companies304,846 SEC filings22,720 clinical trials100% citation-verification pass rate (7d)How we verify →

The AI overview and BioSniper Score are neutral, data-derived signals built from public SEC filings, ClinicalTrials.gov and FDA records — not investment advice.