| GILDGILEAD SCIENCES, INC. | 1,275,099 | $177.7M |
| REGNREGENERON PHARMACEUTICALS, INC. | 140,491 | $108.5M |
| INCYIncyte Corp. | 374,280 | $35.2M |
| EXELEXELIXIS, INC. | 463,825 | $19.9M |
| LGNDLigand Pharmaceuticals Incorporated | 64,133 | $12.8M |
| ALMSALUMIS INC. | 538,733 | $11.9M |
| PTCTPTC THERAPEUTICS, INC. | 164,570 | $11.2M |
| PTGXProtagonist Therapeutics, Inc | 95,235 | $10.0M |
| MRNAModerna, Inc. | 170,898 | $8.7M |
| ACADACADIA PHARMACEUTICALS INC | 387,650 | $8.6M |
| BBIOBridgeBio Pharma, Inc. | 115,392 | $8.6M |
| COGTCogent Biosciences, Inc. | 178,165 | $6.9M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 119,961 | $6.8M |
| TEVATeva Pharmaceutical Industries Limited | 207,156 | $6.2M |
| ARQTArcutis Biotherapeutics, Inc. | 256,545 | $6.0M |
| JAZZJazz Pharmaceuticals plc | 29,575 | $5.6M |
| TGTXTG THERAPEUTICS, INC. | 164,500 | $5.5M |
| APGEApogee Therapeutics, Inc. | 63,900 | $5.4M |
| TERNTerns Pharmaceuticals, Inc. | 96,740 | $5.1M |
| ADPTAdaptive Biotechnologies Corp | 359,100 | $5.0M |
| TVTXTravere Therapeutics, Inc. | 162,235 | $4.8M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 70,140 | $4.4M |
| AXSMAxsome Therapeutics, Inc. | 24,573 | $4.2M |
| CYTKCYTOKINETICS INC | 59,425 | $3.9M |
| APLSApellis Pharmaceuticals, Inc. | 92,510 | $3.7M |
| ANABANAPTYSBIO, INC | 64,050 | $3.6M |
| PCVXVaxcyte, Inc. | 59,325 | $3.4M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 62,875 | $3.3M |
| INVAInnoviva, Inc. | 136,417 | $3.2M |
| KODKodiak Sciences Inc. | 80,215 | $3.1M |
| LQDALiquidia Corp | 80,280 | $3.0M |
| SYRESpyre Therapeutics, Inc. | 59,555 | $3.0M |
| ADMAADMA BIOLOGICS, INC. | 307,050 | $2.8M |
| IONSIONIS PHARMACEUTICALS INC | 35,268 | $2.6M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 30,190 | $2.6M |
| ELVNEnliven Therapeutics, Inc. | 66,940 | $2.6M |
| CMPXCompass Therapeutics, Inc. | 494,300 | $2.6M |
| INSMINSMED Inc | 15,875 | $2.6M |
| HRMYHarmony Biosciences Holdings, Inc. | 81,874 | $2.3M |
| CGEMCullinan Therapeutics, Inc. | 149,445 | $2.1M |
| IBRXImmunityBio, Inc. | 268,370 | $2.1M |
| RCUSArcus Biosciences, Inc. | 87,973 | $1.9M |
| ROIVRoivant Sciences Ltd. | 67,690 | $1.9M |
| OGNOrganon & Co. | 240,527 | $1.8M |
| VCELVericel Corp | 52,581 | $1.7M |
| OLMAOlema Pharmaceuticals, Inc. | 110,150 | $1.6M |
| PBYIPUMA BIOTECHNOLOGY, INC. | 253,039 | $1.6M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 18,126 | $1.5M |
| ANIPANI PHARMACEUTICALS INC | 19,700 | $1.5M |
| RVMDREVOLUTION MEDICINES, INC. | 13,682 | $1.3M |
| ORICOric Pharmaceuticals, Inc. | 96,145 | $1.2M |
| RDYDR REDDYS LABORATORIES LTD | 87,800 | $1.2M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 2,956 | $978K |
| NUVLNuvalent, Inc. | 7,855 | $805K |
| SLNOSOLENO THERAPEUTICS INC | 22,845 | $765K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 24,430 | $743K |
| NRIXNurix Therapeutics, Inc. | 44,200 | $685K |
| FOLDAMICUS THERAPEUTICS, INC. | 46,980 | $679K |
| ARDXARDELYX, INC. | 112,390 | $673K |
| SRRKScholar Rock Holding Corp | 13,615 | $669K |
| DNLIDenali Therapeutics Inc. | 30,570 | $587K |
| ZYMEZymeworks Inc. | 21,970 | $550K |
| BCAXBicara Therapeutics Inc. | 27,330 | $544K |
| SIGASIGA TECHNOLOGIES INC | 100,590 | $538K |
| PGENPRECIGEN, INC. | 138,200 | $535K |
| DSGNDesign Therapeutics, Inc. | 45,810 | $487K |
| TNGXTango Therapeutics, Inc. | 19,160 | $401K |
| BEAMBeam Therapeutics Inc. | 14,925 | $356K |
| ORGOOrganogenesis Holdings Inc. | 145,900 | $346K |
| KURAKura Oncology, Inc. | 41,280 | $336K |
| XERSXeris Biopharma Holdings, Inc. | 57,139 | $331K |
| CLDXCelldex Therapeutics, Inc. | 10,403 | $330K |
| IMVTImmunovant, Inc. | 12,800 | $318K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 9,045 | $306K |
| ORKAOruka Therapeutics, Inc. | 6,040 | $296K |
| IRONDisc Medicine, Inc. | 4,265 | $273K |
| DAWNDay One Biopharmaceuticals, Inc. | 12,260 | $263K |
| STOKStoke Therapeutics, Inc. | 7,640 | $249K |
| VRDNViridian Therapeutics, Inc.\DE | 12,680 | $248K |
| OCULOCULAR THERAPEUTIX, INC | 29,270 | $248K |
| NTLAIntellia Therapeutics, Inc. | 17,530 | $225K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 70,660 | $217K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 51,945 | $182K |
| ESPREsperion Therapeutics, Inc. | 60,330 | $165K |
| NUVBNuvation Bio Inc. | 37,030 | $159K |
| BHVNBiohaven Ltd. | 17,975 | $152K |
| LRMRLarimar Therapeutics, Inc. | 32,793 | $148K |
| GERNGERON CORP | 87,752 | $131K |
| SLSSELLAS Life Sciences Group, Inc. | 28,690 | $121K |
| SVRASavara Inc | 22,175 | $121K |
| ANNXAnnexon, Inc. | 20,180 | $112K |
| ABUSArbutus Biopharma Corp | 23,310 | $105K |
| RGNXREGENXBIO Inc. | 12,410 | $104K |
| PRTAPROTHENA CORP PUBLIC LTD CO | 10,025 | $97K |
| OPKOPKO HEALTH, INC. | 65,556 | $75K |
| AQSTAquestive Therapeutics, Inc. | 17,705 | $73K |
| SANASana Biotechnology, Inc. | 25,265 | $73K |
| ALTAltimmune, Inc. | 21,790 | $67K |
| ABSIAbsci Corporation | 20,865 | $63K |
| PRLDPrelude Therapeutics Inc | 17,420 | $60K |
| LXRXLEXICON PHARMACEUTICALS, INC. | 33,800 | $53K |
| ALECAlector, Inc. | 23,795 | $51K |
| RCKTRocket Pharmaceuticals Inc. | 14,175 | $51K |
| ZNTLZentalis Pharmaceuticals, Inc. | 20,850 | $49K |
| CATXPerspective Therapeutics, Inc. | 10,810 | $45K |
| CCCCC4 Therapeutics, Inc. | 15,950 | $42K |
| AGENAGENUS INC | 12,480 | $42K |
| AVXLANAVEX LIFE SCIENCES CORP. | 12,975 | $40K |
| RZLTRezolute, Inc. | 12,350 | $38K |
| BDTXBlack Diamond Therapeutics, Inc. | 17,150 | $37K |
| FATEFATE THERAPEUTICS INC | 26,330 | $32K |
| VTGNVistagen Therapeutics, Inc. | 53,100 | $30K |
| CHRSCoherus Oncology, Inc. | 16,095 | $27K |
| PLXProtalix BioTherapeutics, Inc. | 10,110 | $22K |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 23,495 | $19K |
| HUMAHumacyte Inc. | 22,165 | $13K |