| GILDGILEAD SCIENCES, INC. | 1,614,500 | $225.0M |
| ROIVRoivant Sciences Ltd. | 6,298,000 | $174.5M |
| RVMDREVOLUTION MEDICINES, INC. | 1,749,000 | $170.1M |
| REGNREGENERON PHARMACEUTICALS, INC. | 130,006 | $100.4M |
| MRNAModerna, Inc. | 1,817,001 | $92.3M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 63,607 | $21.0M |
| INSMINSMED Inc | 104,758 | $17.1M |
| GPCRStructure Therapeutics Inc. | 305,400 | $14.7M |
| SNYSanofi | 304,760 | $14.7M |
| TEVATeva Pharmaceutical Industries Limited | 472,672 | $14.2M |
| INCYIncyte Corp. | 72,543 | $6.8M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 98,990 | $5.5M |
| IBRXImmunityBio, Inc. | 608,774 | $4.7M |
| ABEOABEONA THERAPEUTICS INC. | 500,000 | $2.2M |
| EXELEXELIXIS, INC. | 7,994 | $343K |
| JAZZJazz Pharmaceuticals plc | 1,287 | $243K |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 2,017 | $64K |
| LENZLENZ Therapeutics, Inc. | 5,600 | $51K |
| SMMTSummit Therapeutics Inc. | 2,223 | $42K |
| DFTXDefinium Therapeutics Inc. | 1,708 | $32K |
| ACOGAlpha Cognition Inc. | 5,292 | $28K |
| MISTMilestone Pharmaceuticals Inc. | 23,500 | $28K |
| ONCYONCOLYTICS BIOTECH INC | 24,542 | $21K |
| HROWHARROW, INC. | 497 | $18K |
| CYTKCYTOKINETICS INC | 248 | $16K |
| ZYMEZymeworks Inc. | 554 | $14K |
| GRCEGrace Therapeutics, Inc. | 2,716 | $13K |
| FBRXForte Biosciences, Inc. | 478 | $12K |
| CLDXCelldex Therapeutics, Inc. | 366 | $12K |
| CLLSCellectis S.A. | 3,600 | $11K |
| PLSEPulse Biosciences Inc Common Stock (DE) | 493 | $11K |
| SLSSELLAS Life Sciences Group, Inc. | 2,387 | $10K |
| IRDOpus Genetics, Inc. | 2,014 | $9K |
| GRFSGrifols S.A. | 1,130 | $9K |
| MESOMesoblast Limited | 525 | $8K |
| AXSMAxsome Therapeutics, Inc. | 37 | $6K |
| OPKOPKO HEALTH, INC. | 5,200 | $6K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 1,837 | $6K |
| BEAMBeam Therapeutics Inc. | 213 | $5K |
| ABCLAbCellera Biologics Inc. | 1,393 | $5K |
| AVXLANAVEX LIFE SCIENCES CORP. | 1,500 | $5K |
| ATAIAtai Beckley N.V. | 1,301 | $5K |
| PLXProtalix BioTherapeutics, Inc. | 2,000 | $4K |
| OCGNOcugen, Inc. | 1,804 | $3K |
| RCKTRocket Pharmaceuticals Inc. | 900 | $3K |
| ABUSArbutus Biopharma Corp | 700 | $3K |
| CMPSCOMPASS Pathways plc | 549 | $3K |
| ABSIAbsci Corporation | 1,000 | $3K |
| FLGTFulgent Genetics Inc. | 188 | $3K |
| FLNAFilana Therapeutics Inc. | 1,710 | $3K |
| BCTXBriaCell Therapeutics Corp. | 802 | $3K |
| NUVBNuvation Bio Inc. | 575 | $2K |
| CATXPerspective Therapeutics, Inc. | 582 | $2K |
| PGENPRECIGEN, INC. | 558 | $2K |
| HYFTMindWalk Holdings Corp. | 1,671 | $2K |
| DNAGinkgo Bioworks Holdings Inc. | 276 | $2K |
| KYNBKYNTRA BIO INC. | 193 | $1K |
| CMPXCompass Therapeutics, Inc. | 235 | $1K |
| HUMAHumacyte Inc. | 1,800 | $1K |
| OCULOCULAR THERAPEUTIX, INC | 125 | $1K |
| ATNMActinium Pharmaceuticals, Inc. | 1,021 | $1K |
| CNTACentessa Pharmaceuticals plc | 25 | $993 |
| ZVRAZEVRA THERAPEUTICS, INC. | 69 | $642 |
| ALECAlector, Inc. | 200 | $430 |
| CRBPCorbus Pharmaceuticals Holdings, Inc. | 46 | $428 |
| BIOABioAge Labs, Inc. | 24 | $418 |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 116 | $407 |
| NBTXNanobiotix S.A. | 13 | $394 |
| OGNOrganon & Co. | 54 | $343 |
| NUVLNuvalent, Inc. | 3 | $307 |
| DNTHDianthus Therapeutics, Inc. /DE/ | 3 | $250 |
| SKYESkye Bioscience, Inc. | 400 | $242 |
| KURAKura Oncology, Inc. | 27 | $219 |
| CTMXCytomX Therapeutics, Inc. | 42 | $197 |
| INOINOVIO PHARMACEUTICALS, INC. | 99 | $172 |
| NGNENeurogene Inc. | 8 | $161 |
| SRRKScholar Rock Holding Corp | 3 | $147 |
| NTLAIntellia Therapeutics, Inc. | 11 | $141 |
| JSPRJasper Therapeutics Inc. | 160 | $139 |
| IXHLIncannex Healthcare Inc. | 45 | $135 |
| ALVOAlvotech | 35 | $120 |
| ACETAdicet Bio, Inc. | 17 | $115 |
| DSGNDesign Therapeutics, Inc. | 9 | $96 |
| QNTMQuantum Biopharma Ltd. | 20 | $93 |
| SGMOQSANGAMO THERAPEUTICS, INC | 200 | $49 |
| NNVCNANOVIRICIDES, INC. | 50 | $46 |
| SBFMSUNSHINE BIOPHARMA INC. | 9 | $9 |
| ENVBEnveric Biosciences, Inc. | 1 | $2 |