| TERNTerns Pharmaceuticals, Inc. | 2,779,445 | $146.5M |
| TNGXTango Therapeutics, Inc. | 3,826,659 | $80.1M |
| APLSApellis Pharmaceuticals, Inc. | 1,917,501 | $77.1M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 1,362,752 | $77.0M |
| CYTKCYTOKINETICS INC | 992,545 | $65.4M |
| DAWNDay One Biopharmaceuticals, Inc. | 2,625,235 | $56.3M |
| FOLDAMICUS THERAPEUTICS, INC. | 3,827,513 | $55.3M |
| VRDNViridian Therapeutics, Inc.\DE | 2,315,957 | $45.3M |
| SNYSanofi | 833,780 | $40.2M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 474,085 | $39.8M |
| DMRADamora Therapeutics, Inc. | 1,448,000 | $37.5M |
| APGEApogee Therapeutics, Inc. | 438,654 | $36.9M |
| INSMINSMED Inc | 221,707 | $36.3M |
| CNTACentessa Pharmaceuticals plc | 852,828 | $33.9M |
| MANEVeradermics Incorporated | 532,906 | $33.7M |
| COGTCogent Biosciences, Inc. | 856,598 | $33.0M |
| PTCTPTC THERAPEUTICS, INC. | 460,564 | $31.4M |
| PCVXVaxcyte, Inc. | 514,577 | $29.9M |
| CBIOCRESCENT BIOPHARMA, INC. | 1,510,033 | $27.7M |
| KODKodiak Sciences Inc. | 726,547 | $27.7M |
| BBIOBridgeBio Pharma, Inc. | 350,096 | $26.0M |
| DFTXDefinium Therapeutics Inc. | 1,274,221 | $24.1M |
| KNSAKiniksa Pharmaceuticals International, plc | 499,792 | $24.1M |
| ABVXAbivax SA | 213,689 | $23.8M |
| BIOABioAge Labs, Inc. | 1,327,545 | $23.2M |
| OCULOCULAR THERAPEUTIX, INC | 2,692,622 | $22.8M |
| LBRXLB PHARMACEUTICALS INC | 923,694 | $22.8M |
| ANNXAnnexon, Inc. | 3,886,909 | $21.5M |
| BHVNBiohaven Ltd. | 2,445,416 | $20.7M |
| MLTXMoonLake Immunotherapeutics | 1,065,610 | $19.9M |
| QUREuniQure N.V. | 964,290 | $15.8M |
| RZLTRezolute, Inc. | 5,048,421 | $15.4M |
| GPCRStructure Therapeutics Inc. | 304,934 | $14.7M |
| NGNENeurogene Inc. | 718,389 | $14.5M |
| SABSSAB BIOTHERAPEUTICS, INC. | 3,760,439 | $14.4M |
| MAZEMaze Therapeutics, Inc. | 461,151 | $13.8M |
| PHVSPharvaris N.V. | 462,251 | $13.1M |
| ZBIOZenas BioPharma, Inc. | 667,070 | $13.0M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 206,412 | $12.9M |
| CATXPerspective Therapeutics, Inc. | 2,994,460 | $12.5M |
| IRDOpus Genetics, Inc. | 2,718,029 | $12.4M |
| OVIDOvid Therapeutics Inc. | 5,533,073 | $12.3M |
| ELVNEnliven Therapeutics, Inc. | 310,025 | $12.2M |
| PVLAPALVELLA THERAPEUTICS, INC. | 96,726 | $12.1M |
| AQSTAquestive Therapeutics, Inc. | 2,900,570 | $12.0M |
| KRROKorro Bio, Inc. | 1,040,054 | $11.8M |
| CAMPCamp4 Therapeutics Corp | 2,632,437 | $11.6M |
| STROSUTRO BIOPHARMA, INC. | 465,792 | $11.6M |
| AVTXAvalo Therapeutics, Inc. | 731,586 | $10.9M |
| PTGXProtagonist Therapeutics, Inc | 101,299 | $10.7M |
| SMMTSummit Therapeutics Inc. | 548,335 | $10.4M |
| IMTXImmatics N.V. | 982,864 | $9.7M |
| ARGXARGENX SE | 13,111 | $9.6M |
| CAPRCAPRICOR THERAPEUTICS, INC. | 297,123 | $9.0M |
| INVAInnoviva, Inc. | 322,009 | $7.5M |
| SRRKScholar Rock Holding Corp | 149,714 | $7.4M |
| ACADACADIA PHARMACEUTICALS INC | 312,982 | $7.0M |
| ORICOric Pharmaceuticals, Inc. | 523,790 | $6.6M |
| ALECAlector, Inc. | 2,935,253 | $6.3M |
| SRZNSurrozen Inc. | 203,888 | $5.9M |
| CMPXCompass Therapeutics, Inc. | 1,119,090 | $5.9M |
| PLSEPulse Biosciences Inc Common Stock (DE) | 265,164 | $5.7M |
| JBIOJade Biosciences, Inc. | 402,489 | $5.7M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 52,967 | $4.6M |
| IVVDInvivyd, Inc. | 3,515,644 | $4.6M |
| TNXPTonix Pharmaceuticals Holding Corp. | 313,082 | $4.3M |
| DNLIDenali Therapeutics Inc. | 195,108 | $3.7M |
| CTMXCytomX Therapeutics, Inc. | 730,844 | $3.4M |
| IMCRImmunocore Holdings plc | 113,844 | $3.4M |
| RLYBRallybio Corp | 376,573 | $3.4M |
| RNAAtrium Therapeutics Inc. | 235,115 | $3.1M |
| ABSIAbsci Corporation | 1,045,198 | $3.1M |
| TENXTENAX THERAPEUTICS, INC. | 194,616 | $3.1M |
| SANASana Biotechnology, Inc. | 1,033,804 | $3.0M |
| SYRESpyre Therapeutics, Inc. | 55,477 | $2.8M |
| GILDGILEAD SCIENCES, INC. | 19,774 | $2.8M |
| LQDALiquidia Corp | 72,895 | $2.8M |
| CLDXCelldex Therapeutics, Inc. | 85,026 | $2.7M |
| ABEOABEONA THERAPEUTICS INC. | 589,847 | $2.6M |
| ELTXElicio Therapeutics, Inc. | 244,814 | $2.6M |
| NKTRNEKTAR THERAPEUTICS | 35,851 | $2.6M |
| RVMDREVOLUTION MEDICINES, INC. | 23,799 | $2.3M |
| NTLAIntellia Therapeutics, Inc. | 169,286 | $2.2M |
| NSRXNasus Pharma Ltd | 898,473 | $2.0M |
| WHWKWhitehawk Therapeutics, Inc. | 550,441 | $1.9M |
| RLMDRELMADA THERAPEUTICS, INC. | 252,457 | $1.8M |
| KZIAKAZIA THERAPEUTICS LTD | 193,114 | $1.4M |
| AUTLAutolus Therapeutics plc | 971,691 | $1.3M |
| OLMAOlema Pharmaceuticals, Inc. | 89,671 | $1.3M |
| SGMOQSANGAMO THERAPEUTICS, INC | 5,288,097 | $1.3M |
| OGNOrganon & Co. | 217,900 | $1.3M |
| SLDBSolid Biosciences Inc. | 178,253 | $1.2M |
| ARDXARDELYX, INC. | 200,221 | $1.2M |
| VKTXViking Therapeutics, Inc. | 36,493 | $1.2M |
| REGNREGENERON PHARMACEUTICALS, INC. | 1,505 | $1.2M |
| BDTXBlack Diamond Therapeutics, Inc. | 510,811 | $1.1M |
| MISTMilestone Pharmaceuticals Inc. | 851,325 | $1.0M |
| RCKTRocket Pharmaceuticals Inc. | 259,007 | $927K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 248,764 | $873K |
| IBRXImmunityBio, Inc. | 103,871 | $797K |
| STOKStoke Therapeutics, Inc. | 23,878 | $777K |
| PTNPALATIN TECHNOLOGIES INC | 41,169 | $717K |
| CRBPCorbus Pharmaceuticals Holdings, Inc. | 65,201 | $612K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 18,009 | $609K |
| NEUPNeuphoria Therapeutics Inc. | 142,183 | $579K |
| ABUSArbutus Biopharma Corp | 125,521 | $565K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 167,048 | $513K |
| PGENPRECIGEN, INC. | 128,974 | $499K |
| SPRYARS Pharmaceuticals, Inc. | 61,752 | $496K |
| FBRXForte Biosciences, Inc. | 18,717 | $485K |
| ONCBeOne Medicines Ltd. | 1,503 | $446K |
| BCAXBicara Therapeutics Inc. | 21,797 | $434K |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 6,738 | $348K |
| SLSSELLAS Life Sciences Group, Inc. | 81,695 | $346K |
| INCYIncyte Corp. | 3,322 | $313K |
| VCELVericel Corp | 9,212 | $296K |
| ANABANAPTYSBIO, INC | 4,905 | $272K |
| NUVBNuvation Bio Inc. | 62,521 | $268K |
| MRNAModerna, Inc. | 5,191 | $264K |
| KALVKalVista Pharmaceuticals, Inc. | 11,098 | $223K |
| SVRASavara Inc | 40,017 | $218K |
| CADLCandel Therapeutics, Inc. | 43,208 | $212K |
| RGNXREGENXBIO Inc. | 11,656 | $98K |
| CLYMClimb Bio, Inc. | 6,959 | $48K |