| INCYIncyte Corp. | 30,744,412 | $2.89B |
| ONCBeOne Medicines Ltd. | 8,799,053 | $2.61B |
| INSMINSMED Inc | 7,421,111 | $1.21B |
| ACADACADIA PHARMACEUTICALS INC | 42,896,690 | $954.9M |
| RVMDREVOLUTION MEDICINES, INC. | 9,555,357 | $929.3M |
| KODKodiak Sciences Inc. | 19,919,186 | $759.3M |
| SMMTSummit Therapeutics Inc. | 36,391,063 | $690.0M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 5,604,483 | $487.4M |
| IONSIONIS PHARMACEUTICALS INC | 2,047,727 | $153.8M |
| KNSAKiniksa Pharmaceuticals International, plc | 2,826,246 | $136.1M |
| IMVTImmunovant, Inc. | 5,457,881 | $135.6M |
| ROIVRoivant Sciences Ltd. | 4,867,723 | $134.8M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 1,992,783 | $124.9M |
| STOKStoke Therapeutics, Inc. | 3,336,697 | $108.6M |
| IMTXImmatics N.V. | 10,916,693 | $107.4M |
| ABCLAbCellera Biologics Inc. | 30,275,938 | $105.7M |
| ABVXAbivax SA | 875,796 | $97.5M |
| NRIXNurix Therapeutics, Inc. | 4,658,556 | $72.2M |
| DNLIDenali Therapeutics Inc. | 3,731,695 | $71.6M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 852,164 | $71.5M |
| GPCRStructure Therapeutics Inc. | 1,432,529 | $69.0M |
| TRDAEntrada Therapeutics, Inc. | 5,072,730 | $64.0M |
| BCYCBICYCLE THERAPEUTICS PLC | 10,885,357 | $50.5M |
| SYRESpyre Therapeutics, Inc. | 1,000,000 | $50.4M |
| ALMSALUMIS INC. | 2,012,500 | $44.3M |
| VRDNViridian Therapeutics, Inc.\DE | 1,971,678 | $38.6M |
| ELVNEnliven Therapeutics, Inc. | 905,191 | $35.5M |
| PRLDPrelude Therapeutics Inc | 10,123,824 | $34.6M |
| DSGNDesign Therapeutics, Inc. | 2,585,978 | $27.5M |
| CNTACentessa Pharmaceuticals plc | 670,751 | $26.6M |
| CTMXCytomX Therapeutics, Inc. | 4,975,826 | $23.4M |
| JBIOJade Biosciences, Inc. | 1,641,137 | $23.1M |
| IRONDisc Medicine, Inc. | 349,657 | $22.4M |
| IMCRImmunocore Holdings plc | 734,397 | $22.1M |
| CLDXCelldex Therapeutics, Inc. | 665,370 | $21.1M |
| NGNENeurogene Inc. | 991,691 | $20.0M |
| TECXTectonic Therapeutic, Inc. | 607,788 | $18.8M |
| ARGXARGENX SE | 25,174 | $18.4M |
| SIONSionna Therapeutics, Inc. | 400,000 | $16.0M |
| CMPSCOMPASS Pathways plc | 2,344,720 | $13.0M |
| PHVSPharvaris N.V. | 375,000 | $10.6M |
| RCUSArcus Biosciences, Inc. | 415,621 | $9.0M |
| MPLTMapLight Therapeutics, Inc. | 364,705 | $7.4M |
| ABSIAbsci Corporation | 2,134,803 | $6.4M |
| SGMTSagimet Biosciences Inc. | 952,996 | $5.0M |
| LBRXLB PHARMACEUTICALS INC | 200,000 | $4.9M |
| SKYESkye Bioscience, Inc. | 1,575,243 | $968K |
| SANASana Biotechnology, Inc. | 310,483 | $894K |
| ALGSAligos Therapeutics, Inc. | 83,055 | $617K |