| MRNAModerna, Inc. | 4,051,185 | $205.8M |
| RVMDREVOLUTION MEDICINES, INC. | 1,885,821 | $183.4M |
| TEVATeva Pharmaceutical Industries Limited | 5,519,030 | $166.2M |
| SNYSanofi | 2,306,229 | $111.1M |
| JAZZJazz Pharmaceuticals plc | 411,015 | $77.7M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 1,210,746 | $66.8M |
| PTGXProtagonist Therapeutics, Inc | 593,197 | $62.5M |
| DNLIDenali Therapeutics Inc. | 1,941,123 | $37.3M |
| IONSIONIS PHARMACEUTICALS INC | 473,150 | $35.5M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 472,870 | $29.6M |
| PCVXVaxcyte, Inc. | 435,581 | $25.3M |
| PVLAPALVELLA THERAPEUTICS, INC. | 179,922 | $22.4M |
| LBRXLB PHARMACEUTICALS INC | 863,947 | $21.3M |
| GMABGenmab A/S | 645,481 | $17.3M |
| SLDBSolid Biosciences Inc. | 2,280,125 | $16.4M |
| CNTACentessa Pharmaceuticals plc | 320,430 | $12.7M |
| CYTKCYTOKINETICS INC | 150,000 | $9.9M |
| COGTCogent Biosciences, Inc. | 250,000 | $9.6M |
| ORKAOruka Therapeutics, Inc. | 184,863 | $9.1M |
| ABCLAbCellera Biologics Inc. | 2,592,105 | $9.0M |
| OCSOculis Holding AG | 331,332 | $8.8M |
| ALTAltimmune, Inc. | 2,644,600 | $8.1M |
| IRONDisc Medicine, Inc. | 125,000 | $8.0M |
| INSMINSMED Inc | 48,122 | $7.9M |
| SLNOSOLENO THERAPEUTICS INC | 217,500 | $7.3M |
| APGEApogee Therapeutics, Inc. | 75,000 | $6.3M |
| CMPSCOMPASS Pathways plc | 1,000,000 | $5.5M |
| SIONSionna Therapeutics, Inc. | 136,222 | $5.5M |
| TERNTerns Pharmaceuticals, Inc. | 100,000 | $5.3M |
| CBIOCRESCENT BIOPHARMA, INC. | 264,000 | $4.8M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 52,247 | $4.4M |
| LENZLENZ Therapeutics, Inc. | 463,495 | $4.2M |
| CHRSCoherus Oncology, Inc. | 2,250,000 | $3.8M |
| NKTRNEKTAR THERAPEUTICS | 50,000 | $3.6M |
| PHVSPharvaris N.V. | 125,000 | $3.5M |
| KLRSKalaris Therapeutics, Inc. | 572,687 | $3.3M |
| ALGSAligos Therapeutics, Inc. | 412,000 | $3.1M |
| MAZEMaze Therapeutics, Inc. | 100,000 | $3.0M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 32,589 | $2.8M |
| LRMRLarimar Therapeutics, Inc. | 617,211 | $2.8M |
| UPBUpstream Bio, Inc. | 298,329 | $2.7M |
| VERUVERU INC. | 1,000,000 | $2.2M |
| ACOGAlpha Cognition Inc. | 365,000 | $2.0M |
| ORICOric Pharmaceuticals, Inc. | 137,489 | $1.7M |
| INABIN8BIO, INC. | 944,319 | $1.4M |
| ACETAdicet Bio, Inc. | 203,799 | $1.4M |
| BIOABioAge Labs, Inc. | 75,000 | $1.3M |
| AGMBAgomAb Therapeutics NV | 75,000 | $787K |
| TNGXTango Therapeutics, Inc. | 17,198 | $360K |
| SRZNSurrozen Inc. | 10,188 | $297K |
| ADAGAdagene Inc. | 20,710 | $81K |
| HOWLWerewolf Therapeutics, Inc. | 86,554 | $72K |