HER2

106 drugs in development·46 companies·3 clinical trials

Drug Pipeline by Phase

Approved(16)

Drug	Company
afinitor	Novartis AG (NVS)
everolimus	Mylan II B.V. (MYL)
ibrance	PFIZER INC (PFE)
Inluriyo	ELI LILLY & Co (LLY)
kisqali femara co-pack	Novartis AG (NVS)
MARGENZA	MACROGENICS INC (MGNX)
menacalc	METASTAT, INC. (MTST)
metsera's monthly met-097i+met-233i combination	PFIZER INC (PFE)
ogivri	Mylan II B.V. (MYL)
Ontruzant (SB3)	Organon & Co. (OGN)
trodelvy	Immunome Inc. (IMNM)
tukysa	Seagen Inc. (SGEN)
tykerb	Novartis AG (NVS)
Verzenio®	ELI LILLY & Co (LLY)
ziihera	Zymeworks Inc. (ZYME)
Ziihera	Jazz Pharmaceuticals plc (JAZZ)

Phase 3(34)

Drug	Company
arx788	Ambrx Biopharma Cayman, Inc. (AMAM)
azd9833	ASTRAZENECA PLC (AZN)
bgb-43395	BeOne Medicines Ltd. (ONC)
BGB-43395	BeOne Medicines Ltd. (ONC)
bl-m07d1	Takeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock) (TAK)
bl-m07d1	TAKEDA PHARMACEUTICAL CO LTD (TKPHF)
Camizestrant	ASTRAZENECA PLC (AZN)
combination product	PFIZER INC (PFE)
Datopotamab Deruxtecan	Merus N.V. (MRUS)
elacestrant	Radius Health, Inc. (RDUS)
Eribulin	Jazz Pharmaceuticals plc (JAZZ)
Giredestrant	ENANTA PHARMACEUTICALS INC (ENTA)
Hormone Therapy	Filana Therapeutics Inc. (FLNA)
LHRH Agonist	ENANTA PHARMACEUTICALS INC (ENTA)
luteinizing hormone-releasing hormone agonist	ASTRAZENECA PLC (AZN)
Palazestrant	ARS Pharmaceuticals, Inc. (SPRY)
Palazestrant	Olema Pharmaceuticals, Inc. (OLMA)
palazestrant (formerly known as OP-1250)	Olema Pharmaceuticals, Inc. (OLMA)
palazestrant (OP-1250)	Olema Pharmaceuticals, Inc. (OLMA)
pertuzumab	Takeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock) (TAK)
pertuzumab	NOVARTIS AG (NVSEF)
pertuzumab	PFIZER INC (PFE)
pertuzumab	Novartis AG (NVS)
pertuzumab	TAKEDA PHARMACEUTICAL CO LTD (TKPHF)
Pertuzumab	Merus N.V. (MRUS)
Pertuzumab	ASTRAZENECA PLC (AZN)
Pertuzumab IV	Filana Therapeutics Inc. (FLNA)
t-dm1	PFIZER INC (PFE)
T-DM1	BioNTech SE (BNTX)
Taxane	ASTRAZENECA PLC (AZN)
Tucatinib	PFIZER INC (PFE)
Tucatinib	ENANTA PHARMACEUTICALS INC (ENTA)
vepdegestrant	ARVINAS, INC. (ARVN)
Vinorelbine	Jazz Pharmaceuticals plc (JAZZ)

Phase 2(20)

Drug	Company
AZD8421	ASTRAZENECA PLC (AZN)
Ceterizine	ASTRAZENECA PLC (AZN)
denikitug	GILEAD SCIENCES, INC. (GILD)
Eftilagimod Alfa	Filana Therapeutics Inc. (FLNA)
Eftilagimod Alfa	Structure Therapeutics Inc. (GPCR)
Ifinatamab Deruxtecan	Merus N.V. (MRUS)
l-nmma	GH Research PLC (GHRS)
L-NMMA	Novartis AG (NVS)
L-NMMA	ENANTA PHARMACEUTICALS INC (ENTA)
L-NMMA	Cidara Therapeutics, Inc. (CDTX)
L-NMMA	ADMA BIOLOGICS, INC. (ADMA)
L-NMMA	Relay Therapeutics, Inc. (RLAY)
L-NMMA	ARROWHEAD PHARMACEUTICALS, INC. (ARWR)
Leucovorin	Jazz Pharmaceuticals plc (JAZZ)
Loperamide	ASTRAZENECA PLC (AZN)
Patritumab Deruxtecan	Merus N.V. (MRUS)
Pertuzumab	Jazz Pharmaceuticals plc (JAZZ)
ramucirumab	GILEAD SCIENCES, INC. (GILD)
RO7771950	ENANTA PHARMACEUTICALS INC (ENTA)
vir-5818	Vir Biotechnology, Inc. (VIR)

Phase 1(20)

Drug	Company
adxs-her2	OLD AYALA, INC (AYLA)
ADXS-HER2 (ADXS31-164)	Ayala Pharmaceuticals, Inc. (ADXS)
bgb-43395	BeOne Medicines Ltd. (ONC)
CT-0508	Carisma Therapeutics Inc. (CARM)
CT-0525	Carisma Therapeutics Inc. (CARM)
elvn-002	Enliven Therapeutics, Inc. (ELVN)
eribulin	Enliven Therapeutics, Inc. (ELVN)
Evorpacept	Jazz Pharmaceuticals plc (JAZZ)
iev407	NOVARTIS AG (NVSEF)
iev407	Novartis AG (NVS)
leucovorin	Enliven Therapeutics, Inc. (ELVN)
MT-304	ENANTA PHARMACEUTICALS INC (ENTA)
OP-3136	Olema Pharmaceuticals, Inc. (OLMA)
pepinemab	GH Research PLC (GHRS)
Pertuzumab Injection	BioNTech SE (BNTX)
Ritonavir	BioNTech SE (BNTX)
tos-358	MEDICINES CO /DE (MDCO)
xmt-2056	Day One Biopharmaceuticals, Inc. (DAWN)
xmt-2056	Mersana Therapeutics, Inc. (MRSN)
Zanidatamab	Jazz Pharmaceuticals plc (JAZZ)

Preclinical(2)

Drug	Company
SNAP-CAR Platform	Coeptis Therapeutics Holdings Inc. (COEP)
StemPrintER	Accustem Sciences Inc. (ACUT)

Unknown(2)

Drug	Company
b-cell lymphoma 2 protein inhibitor	GH Research PLC (GHRS)
HLX11	Organon & Co. (OGN)

Early Phase 1(1)

Drug	Company
177lu-rad202	Radiopharm Theranostics Limited (RADX)

Phase 1/Phase 2(9)

Drug	Company
avzo-021	AVENUE THERAPEUTICS, INC. (ATXI)
avzo-023	AVENUE THERAPEUTICS, INC. (ATXI)
bpx-603	BELLICUM PHARMACEUTICALS, INC (BLCM)
eci830	NOVARTIS AG (NVSEF)
eci830	Novartis AG (NVS)
erw316	Novartis AG (NVS)
gvv858	Novartis AG (NVS)
GVV858	Novartis AG (NVS)
Itraconazole	BioNTech SE (BNTX)

Phase 2/Phase 3(1)

Drug	Company
utidelone	BIOSTAR PHARMACEUTICALS, INC. (BSPM)

Phase 4(1)

Drug	Company
Alpelisib	Novartis AG (NVS)

Compare drugs

afinitor vs everolimus afinitor vs ibrance afinitor vs Inluriyo

Frequently asked questions

How many drugs are in development for HER2?

BioSniper tracks 106 drugs in development for HER2 across 46 companies.

How many clinical trials target HER2?

There are 3 clinical trials targeting HER2 tracked by BioSniper.

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