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ritonavir

Generic: RITONAVIR·Brand: Kaletra, NORVIR, Norvir, RITONAVIR

ritonavir: developed by 1 company · 5 clinical trials tracked · 2 FDA decisions.

ritonavir evidence translation

What we can confirm

2 FDA records · 5 tracked trials

What it means

Source-backed records connect ritonavir to ABBV; that link alone does not prove the drug works.

What to watch

Watch active trials and any change in FDA or trial status.
BioSniper AIPage evidence connected

Prepared research question

How could ritonavir → ABBV affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 0 study sponsors

Related indications

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
AbbVie Inc. (ABBV)Approved
Clinical Trials (5)

A Phase 1/2a, Multicenter, Open-Label, First in Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of DB-1303/BNT323 in Patients With Advanced/Metastatic Solid Tumors

NCT05150691·Phase 1/Phase 2
Recruiting

Primary endpoint: Phase 1: Percentage of Participants with Dose-Limiting Toxicities (DLTs) as assessed by CTCAE v5.0.

InterventionalRandomizedopen796 targetStarted 2022-01Completion 2027-1050 sites · Australia, China, United StatesDualityBio Inc.

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

Terminated

Primary endpoint: Number of Women Who Meet Area Under the Curve (AUC) Target in Plasma (Component 1)

Observational205 enrolledStarted 2021-09Completion 2025-0723 sites · Brazil, India, Kenya, Puerto Rico…National Institute of Allergy and Infectious Diseases (NIAID)

Once Daily (QD) Dosing of Lonafarnib (LNF) Co-administered With Ritonavir (RTV) for Treatment of Chronic Hepatitis D Virus Infection

NCT05229991·Phase 3
Completed

Primary endpoint: Viral load change

Interventionalopen10 enrolledStarted 2021-05Completion 2025-023 sites · Israel, New Zealand, Turkey (Türkiye)Soroka University Medical Center

Pilot Study to Measure Exposure to Atazanavir, as a Component of Pharmacokinetic Parameters and Adherence Measured With MEMS in Naive HIV-infected Patients Treated Once Daily With Atazanavir Combined to Ritonavir and to Tenofovir/Emtricitabine. ANRS 134 Cophar 3

NCT00528060·Phase 2
Completed

Primary endpoint: pharmacokinetic parameters of atazanavir (ATV) when combined with ritonavir (RTV) and tenofovir/emtricitabine

Interventionalopen35 enrolledStarted 2008-01Completion 2008-112 sites · FranceFrench National Agency for Research on AIDS and Viral Hepatitis

A Randomized Multicenter Study With Non-inferiority Hypothesis, Comparing the Availability to Maintain a Complete Viral Suppression by a Monotherapy of Darunavir/r to a NRTI Containing Regimen Including Darunavir/r, in HIV-1 Infected Patients With Previous Prolonged Complete Viral Suppression. ANRS 136 MONOI

NCT00421551·Phase 3
Completed

Primary endpoint: Proportion of patients with virological success, the virological failure is defined as 2 consecutive plasma viral load measurements greater or equal to 400 cp/ml within 2 weeks at W48

InterventionalRandomizedopen225 enrolledStarted 2007-03Completion 2011-021 site · FranceFrench National Agency for Research on AIDS and Viral Hepatitis
FDA Decisions2 records
NDA209512Type 3 - New Dosage FormOrphan DrugPriorityOralPowder
Approval1 INDICATIONS AND USAGE NORVIR tablets are indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection. NORVIR oral powder is indicated in combination with other antiretroviral agents for the treatment of pediatric patients with HIV-1 infection. NORVIR tablets are HIV protease inhibitors indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection ( 1 ) NORVIR oral powder is indicated in combination with other antiretroviral ag(ABBV)FDA ↗
NDA022417Type 3 - New Dosage FormStandardOralTablet

Frequently asked questions

Who is developing ritonavir?

ritonavir is being developed by AbbVie Inc..

How many clinical trials involve ritonavir?

BioSniper tracks 5 clinical trials involving ritonavir.

What is ritonavir's latest FDA decision?

The most recent tracked FDA decision for ritonavir is Approval, dated June 7, 2017.