Coma

·MeSH: Coma

140 drugs in development·64 companies·1 clinical trial

Drug Pipeline by Phase

Approved(21)

Drug	Company
acetazolamide	ACHIEVE LIFE SCIENCES, INC. (ACHV)
acetazolamide	ACADIA PHARMACEUTICALS INC (ACAD)
acetazolamide	Prestige Consumer Healthcare Inc. (PBH)
acetazolamide	Greenwich LifeSciences, Inc. (GLSI)
acetazolamide	Mylan II B.V. (MYL)
acetazolamide	MANNKIND CORP (MNKD)
bimatoprost	Amneal Pharmaceuticals, Inc. (AMRX)
brimonidine	Amneal Pharmaceuticals, Inc. (AMRX)
canine osteosarcoma vaccine	ARATANA THERAPEUTICS, INC. (PETX)
cosopt pf	AKORN INC (AKRX)
eribulin	DR REDDYS LABORATORIES LTD (RDY)
leucovorin calcium preservative free	Seagen Inc. (SGEN)
leucovorin calcium preservative free	Mylan II B.V. (MYL)
levothyroxine	MAIA Biotechnology, Inc. (MAIA)
rescula	SUCAMPO PHARMACEUTICALS, INC. (SCMP)
rhopressa	AERIE PHARMACEUTICALS INC (AERI)
rocklatan	AERIE PHARMACEUTICALS INC (AERI)
solx gold shunt	SPOTLIGHT INNOVATION INC. (STLT)
tecelra	Adaptimmune Therapeutics PLC (ADAP)
timolol	Amneal Pharmaceuticals, Inc. (AMRX)
zioptan	AKORN INC (AKRX)

Phase 3(20)

Drug	Company
actinomycin d	GH Research PLC (GHRS)
azenosertib (ZN-c3)	Zentalis Pharmaceuticals, Inc. (ZNTL)
bim-drs	SpyGlass Pharma Inc. (SGP)
Cabozantinib S-malate	Valneva SE (VALN)
cmb305	IMMUNE DESIGN CORP. (IMDZ)
Dactinomycin	Filana Therapeutics Inc. (FLNA)
Dactinomycin	Merus N.V. (MRUS)
eribulin	INTENSITY THERAPEUTICS, INC. (INTS)
int230-6	INTENSITY THERAPEUTICS, INC. (INTS)
Lurbinectedin	Crinetics Pharmaceuticals, Inc. (CRNX)
OTX-TIC	OCULAR THERAPEUTIX, INC (OCUL)
pazopanib	INTENSITY THERAPEUTICS, INC. (INTS)
RP1 (vusolimogene oderparepvec)	Replimune Group, Inc. (REPL)
Single-agent chemotherapy	PTC THERAPEUTICS, INC. (PTCT)
TBI-1301	Filana Therapeutics Inc. (FLNA)
til	GH Research PLC (GHRS)
vincristin	GH Research PLC (GHRS)
Vincristine	Black Diamond Therapeutics, Inc. (BDTX)
vincristine liposomal	GH Research PLC (GHRS)
Vinorelbine Tartrate	Filana Therapeutics Inc. (FLNA)

Phase 2(31)

Drug	Company
^1^1c-methionine	GH Research PLC (GHRS)
AG-120	AGIOS PHARMACEUTICALS, INC. (AGIO)
Cabozantinib S-malate	Assertio Holdings, Inc. (ASRT)
Combination of MK3475 with Metronomic CP	Design Therapeutics, Inc. (DSGN)
Combination of MK3475 with Metronomic CP and G100	Design Therapeutics, Inc. (DSGN)
cyt-0851	Cyteir Therapeutics, Inc. (CYT)
Dacarbazine	PTC THERAPEUTICS, INC. (PTCT)
dexrazoxane	GH Research PLC (GHRS)
Durysta, Bimatoprost Intracameral Implant 10 µg	OCULAR THERAPEUTIX, INC (OCUL)
Elraglusib Injection	ACTUATE THERAPEUTICS, INC. (ACTU)
envafolimab	Tracon Pharmaceuticals, Inc. (TCON)
ifosfamide	Black Diamond Therapeutics, Inc. (BDTX)
imx-110	Immix Biopharma, Inc. (IMMX)
lete-cel	Adaptimmune Therapeutics PLC (ADAP)
ln-145	IOVANCE BIOTHERAPEUTICS, INC. (IOVA)
Lurbinectedin	Jazz Pharmaceuticals plc (JAZZ)
mecbotamab vedotin	BioAtla, Inc. (BCAB)
myeloid growth factor	GH Research PLC (GHRS)
ost-her2	OS Therapies Inc (OSTX)
ozekibart	Inhibrx Biosciences, Inc. (INBX)
Pegfilgrastim	ENANTA PHARMACEUTICALS INC (ENTA)
Pioglitazone Oral Product	Merus N.V. (MRUS)
Regorafenib	Filana Therapeutics Inc. (FLNA)
sbi-100 ophthalmic emulsion	Skye Bioscience, Inc. (SKYE)
sotigalimab	Apexigen, Inc. (APGN)
Temozolomide	ELI LILLY & Co (LLY)
temsirolimus	Black Diamond Therapeutics, Inc. (BDTX)
Trabectedin	Merus N.V. (MRUS)
Unesbulin	PTC THERAPEUTICS, INC. (PTCT)
vincristine	GH Research PLC (GHRS)
vinorelbine	GH Research PLC (GHRS)

Phase 1(39)

Drug	Company
177lu-pnt6555	POINT Biopharma Global Inc. (PNT)
ADCT-601	ADC Therapeutics SA (ADCT)
adxs-her2	OLD AYALA, INC (AYLA)
ADXS-HER2 (ADXS31-164)	Ayala Pharmaceuticals, Inc. (ADXS)
azenosertib	Zentalis Pharmaceuticals, Inc. (ZNTL)
B7-H3-CAR T Cells	Merus N.V. (MRUS)
B7-H3-CAR T Cells	Filana Therapeutics Inc. (FLNA)
CLD-201 (SuperNova™ / SNV1)	Calidi Biotherapeutics Inc. (CLDI)
FH FOLR1 ST CAR T-cells	Filana Therapeutics Inc. (FLNA)
Filgrastim	Black Diamond Therapeutics, Inc. (BDTX)
Filgrastim	PTC THERAPEUTICS, INC. (PTCT)
Filgrastim	ENANTA PHARMACEUTICALS INC (ENTA)
Ganitumab	Black Diamond Therapeutics, Inc. (BDTX)
GCAR1	Filana Therapeutics Inc. (FLNA)
HDM201	Novartis AG (NVS)
INBRX-109	Merus N.V. (MRUS)
INBRX-109	PTC THERAPEUTICS, INC. (PTCT)
INBRX-109	IGM Biosciences, Inc. (IGMS)
incb059872	Incyte Corp. (INCY)
lb-100	LIXTE BIOTECHNOLOGY HOLDINGS, INC. (LIXT)
leucovorin	Inhibrx Biosciences, Inc. (INBX)
Leucovorin	PTC THERAPEUTICS, INC. (PTCT)
LN-145	IOVANCE BIOTHERAPEUTICS, INC. (IOVA)
mRNA plus Lysate-loaded Dendritic Cell Vaccine	ENANTA PHARMACEUTICALS INC (ENTA)
Pazopanib	PTC THERAPEUTICS, INC. (PTCT)
Pazopanib	Novartis AG (NVS)
PEEL-224	ENANTA PHARMACEUTICALS INC (ENTA)
PEEL-224	Structure Therapeutics Inc. (GPCR)
PEEL-224	Black Diamond Therapeutics, Inc. (BDTX)
PEEL-224	PTC THERAPEUTICS, INC. (PTCT)
Pegfilgrastim	PTC THERAPEUTICS, INC. (PTCT)
Pegfilgrastim	Black Diamond Therapeutics, Inc. (BDTX)
PEGYLATED-INTERFERON ALPHA-2A	ENANTA PHARMACEUTICALS INC (ENTA)
pemetrexed	PTC THERAPEUTICS, INC. (PTCT)
Peposertib	Accustem Sciences Inc. (ACUT)
Peposertib	Merus N.V. (MRUS)
Temozolomide	Structure Therapeutics Inc. (GPCR)
trifluridine + tipiracil	Inhibrx Biosciences, Inc. (INBX)
Vincristine	Structure Therapeutics Inc. (GPCR)

Preclinical(9)

Drug	Company
ec17	ENDOCYTE INC (ECYT)
inm-088	InMed Pharmaceuticals Inc. (INM)
LRRC15 monoclonal antibody	Lantheus Holdings, Inc. (LNTH)
man 01	Q BioMed Inc. (QBIO)
man-01	Q BioMed Inc. (QBIO)
man-dox	NAVIDEA BIOPHARMACEUTICALS, INC. (NAVB)
ost-tadc	OS Therapies Inc (OSTX)
ost-tadc-a	OS Therapies Inc (OSTX)
sw-3431	SpringWorks Therapeutics, Inc. (SWTX)

Unknown(2)

Drug	Company
AT-014	Ayala Pharmaceuticals, Inc. (ADXS)
Bleomycin Sulfate	ENANTA PHARMACEUTICALS INC (ENTA)

N/A(10)

Drug	Company
Ganitumab	Filana Therapeutics Inc. (FLNA)
Ganitumab	PTC THERAPEUTICS, INC. (PTCT)
Ifosfamide	PTC THERAPEUTICS, INC. (PTCT)
Pazopanib	Black Diamond Therapeutics, Inc. (BDTX)
Pazopanib	Filana Therapeutics Inc. (FLNA)
Polyethylene Glycol	Filana Therapeutics Inc. (FLNA)
Polyethylene Glycol	Black Diamond Therapeutics, Inc. (BDTX)
Polyethylene Glycol	PTC THERAPEUTICS, INC. (PTCT)
Temsirolimus	PTC THERAPEUTICS, INC. (PTCT)
Vincristine	PTC THERAPEUTICS, INC. (PTCT)

Phase 1/Phase 2(3)

Drug	Company
agn-193408 sr	AbbVie Inc. (ABBV)
interleukin-2	GH Research PLC (GHRS)
pf-07220060	PFIZER INC (PFE)

Phase 2/Phase 3(1)

Drug	Company
inbrx-109	Inhibrx Biosciences, Inc. (INBX)

Phase 4(4)

Drug	Company
anti-vascular endothelial growth factor	GH Research PLC (GHRS)
artificial tears	GH Research PLC (GHRS)
Dactinomycin	ENANTA PHARMACEUTICALS INC (ENTA)
netarsudil ophthalmic solution 0.02%	GH Research PLC (GHRS)

Compare drugs

acetazolamide vs bimatoprost acetazolamide vs brimonidine acetazolamide vs canine osteosarcoma vaccine

Frequently asked questions

How many drugs are in development for Coma?

BioSniper tracks 140 drugs in development for Coma across 64 companies.

How many clinical trials target Coma?

There are 1 clinical trial targeting Coma tracked by BioSniper.

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