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talquetamab

Generic: talquetamab·Brand: Talvey

talquetamab: 15 clinical trials tracked.

talquetamab evidence translation

What we can confirm

15 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about talquetamab, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 2 study sponsors
Clinical Trials (15)showing 10 most recent

TAlquetamab and BeLantamab Mafodotin in Relapsed/Refractory Multiple Myeloma (TaBleMM)

NCT07720843·Phase 1
Not yet recruiting

Primary endpoint: Frequency and severity of treatment emergent adverse events (TEAEs)

Interventionalopen50 targetStarted 2026-09Completion 2032-03Montefiore Medical Center

Phase 3 Randomized Study of Teclistamab and Talquetamab (Tec-Tal) Versus Daratumumab and Lenalidomide (DR) in Minimal Residual Disease (MRD) Positive Patients With Newly Diagnosed Multiple Myeloma After Autologous Hematopoietic Stem Cell Transplantation (TiTan)

NCT07740486·Phase 3
Not yet recruiting

Primary endpoint: Proportion of Participants Achieving MRD Negativity With Complete Response

InterventionalRandomizedopen248 targetStarted 2026-09Completion 2033-04Polish Myeloma Consortium

Phase 2 Study of Cytokine Release Syndrome Prophylaxis With Infliximab for Teclistamab/Talquetamab Therapy in Patients With Relapsed/Refractory Myeloma

NCT07657312·Phase 2
Recruiting

Primary endpoint: Incidence of all-grade cytokine release syndrome (CRS)

Interventionalopen35 targetStarted 2026-08Completion 2027-121 site · United StatesNaresh Bumma

iFIT (UK-MRA Myeloma XVIII): Immunotherapy Approaches Adapted for Fitness in Newly Diagnosed Transplant Ineligible Patients With Myeloma

NCT07649525·Phase 3
Recruiting

Primary endpoint: iFIT1: Progression-free survival (PFS)

InterventionalRandomizedopen1,226 targetStarted 2026-07Completion 2037-065 sites · United KingdomUniversity of Leeds

A Phase 2, Open-Label, Multicenter Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma

NCT06550895·Phase 2
Active, not recruiting

Primary endpoint: Number of Participants With Adverse Events (AE) by Severity According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE) version 5.0

Interventionalopen11 targetStarted 2024-09Completion 2027-089 sites · Australia, United StatesJanssen Research & Development, LLC

A Phase 2, Open-label, Randomized Study to Evaluate GPRC5D-related Oral Events

NCT06500884·Phase 2·GHRS
Recruiting

Primary endpoint: Percentage of Participants With Occurrence of Dysgeusia as Assessed by the Total Waterless Empirical Taste Test (WETT) Testing Score During the Prophylaxis Treatment Phase

InterventionalRandomizedopen210 targetStarted 2024-08Completion 2030-0538 sites · Brazil, Netherlands, Puerto Rico, South Korea…Janssen Research & Development, LLC

A Phase 2, Open-label Study to Evaluate the Efficacy and Safety of Different Sequences of Ciltacabtagene Autoleucel (Cilta-cel), Talquetamab SC in Combination With Daratumumab SC (Tal-D) and Teclistamab SC in Combination With Daratumumab SC (Tec-D) Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

NCT06577025·Phase 2·GHRS
Active, not recruiting

Primary endpoint: Rate of Response with Curative Potential

InterventionalRandomizedopen43 targetStarted 2024-08Completion 2030-0916 sites · Australia, Brazil, Germany, Spain…Janssen Research & Development, LLC

64407564MMY3009: A Phase 3 Randomized Study Comparing Talquetamab in Combination With Pomalidomide (Tal-P), Talquetamab in Combination With Teclistamab (Tal-Tec), and Investigator's Choice of Either Elotuzumab, Pomalidomide, and Dexamethasone (EPd) or Pom

NCT06208150·Phase 3·GHRS
Active, not recruiting

Primary endpoint: Progression Free Survival (PFS)

InterventionalRandomizedopen838 enrolledStarted 2024-01Completion 2028-1250 sites · Argentina, United StatesJanssen Research & Development, LLC

Teclistamab or Talquetamab in Combination With Daratumumab SC for High-Risk Smoldering Myeloma: A Clinical and Correlative Phase 2 Sequential Cohort Immuno-Oncology Study to REVIVE Early Myeloma

NCT06100237·Phase 2·FATE
Recruiting

Primary endpoint: Minimal Residual Disease (MRD) Negative as Measured by Flow Cytometry

Interventionalopen50 targetStarted 2023-12Completion 2029-121 site · United StatesCarl Ola Landgren, MD, PhD

Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma

NCT05972135·Phase 2
Recruiting

Primary endpoint: Incidence of CRS of any grade during the first two cycles

Interventionalopen100 targetStarted 2023-10Completion 2027-1017 sites · United StatesSCRI Development Innovations, LLC