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ibuprofen

Generic: IBUPROFEN·Brand: ACHES-N-PAIN, ADVIL, ADVIL LIQUI-GELS, ADVIL MIGRAINE LIQUI-GELS, CALDOLOR, CAP-PROFEN, CHILDREN'S ADVIL, CHILDREN'S ADVIL-FLAVORED, CHILDREN'S ELIXSURE, CHILDREN'S IBUPROFEN, CHILDREN'S MOTRIN, Caldolor, IBU, IBU-TAB, IBU-TAB 200, IBUPRIN, IBUPROFEN, IBUPROFEN SODIUM, IBUPROHM, INFANT'S ADVIL, Ibu, JUNIOR STRENGTH ADVIL, JUNIOR STRENGTH IBUPROFEN, JUNIOR STRENGTH MOTRIN, MEDIPREN, MIDOL, MIDOL LIQUID GELS, MOTRIN, MOTRIN IB, MOTRIN MIGRAINE PAIN, NUPRIN, Neoprofen, PEDIATRIC ADVIL, RUFEN, TAB-PROFEN

ibuprofen: 10 clinical trials tracked.

ibuprofen evidence translation

What we can confirm

10 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about ibuprofen, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence6 indications · 5 study sponsors
Clinical Trials (10)

Effects of Preemptive Ibuprofen Administration on Delayed Neurocognitive Recovery in Geriatric Patients Undergoing Inguinal Hernia Surgery

NCT07424001·Phase 4·VALN
Completed

Primary endpoint: Montreal Cognitive Assessment (MoCA) Score.

InterventionalRandomizedquadruple76 enrolledStarted 2025-09Completion 2026-011 site · Turkey (Türkiye)Mehmet Çiğdem

Non-Steroidal Anti-Inflammatory Drugs Versus Conventional Treatment in Acute Myocarditis (INFLAMA Trial)

NCT06686862·Phase 3·FLNA
Recruiting

Primary endpoint: Change in late gadolinium enhancement (measured in % relative to indexed myocardial mass) compared to baseline (CMR) at admission)

InterventionalRandomizedsingle150 targetStarted 2025-04Completion 2027-101 site · SpainFundación Centro Nacional de Investigaciones Cardiovasculares Carlos III

A Randomized Controlled Trial of Opioid vs Non-Opioid Postoperative Pain Management in Children With Supracondylar Humerus Fractures

NCT05640674·Phase 4·FLNA
Terminated

Primary endpoint: Daily Pain Scores on the FACES Scale

InterventionalRandomizedopen29 targetStarted 2023-09Completion 2025-123 sites · United StatesBaylor College of Medicine

Multimodal Nonopioid Pain Protocol Following Shoulder Arthroplasty Surgery

NCT05488847·Phase 4·FLNA
Active, not recruiting

Primary endpoint: Pain Levels

InterventionalRandomizedsingle83 targetStarted 2022-06Completion 2026-091 site · United StatesHenry Ford Health System

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

NCT07006675·Phase 3·UTHR
Recruiting

Primary endpoint: Secondary surgery to promote bone union after 3 months post initial surgery

InterventionalRandomizeddouble1,000 targetStarted 2021-05Completion 2027-0314 sites · Canada, United StatesMajor Extremity Trauma Research Consortium

Phase I/II Trial of HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PD-L1/TGF-Beta Trap (M7824) in Subjects With HPV Positive Cancers

NCT04432597·Phase 1·ARWR
Active, not recruiting

Primary endpoint: Safety and recommended phase II dose of PRGN-2009

Interventionalopen39 targetStarted 2020-08Completion 2026-031 site · United StatesNational Cancer Institute (NCI)

A Phase 3b, Open-Label Study of HTX-011 as Part of a Scheduled Non-Opioid Multimodal Analgesic Regimen in Subjects Undergoing Total Knee Arthroplasty

NCT03974932·Phase 3·HRTX
Completed

Primary endpoint: Mean Area Under the Curve (AUC) of the Visual Analogue Scale (VAS).

Interventionalopen116 enrolledStarted 2019-06Completion 2021-016 sites · United StatesHeron Therapeutics

A Phase 3b, Randomized, Open-Label Study of HTX-011 as the Foundation of a Non-opioid, Multimodal Analgesic Regimen to Decrease Opioid Use Following Unilateral Open Inguinal Herniorrhaphy

NCT03907176·Phase 3·HRTX
Completed

Primary endpoint: Proportion of Subjects Who do Not Receive an Opioid Prescription Through the Day 15 Visit

Interventionalopen209 enrolledStarted 2019-04Completion 2021-1130 sites · United StatesHeron Therapeutics

The Effects of Combination Therapy of Opioids Versus Non-Opioids on Postoperative Pain Management After Knee Arthroscopic Surgery: A Prospective Randomized Controlled Study

NCT03858231·Phase 4·FLNA
Recruiting

Primary endpoint: Change from Baseline Pain Assessment at 2 weeks

InterventionalRandomizedtriple148 targetStarted 2018-10Completion 2028-011 site · United StatesSanford Health

A Phase 2, Open-Label Study of HTX 011 in a Multimodal Analgesic Regimen for Decreased Opioid Use Following Unilateral Open Inguinal Herniorrhaphy

NCT03695367·Phase 2·HRTX
Completed

Primary endpoint: Percentage of Subjects Receiving no Opioid Rescue

Interventionalopen63 enrolledStarted 2018-10Completion 2018-125 sites · United StatesHeron Therapeutics