Pain

Pain·MeSH: Chronic Pain

293 drugs in development·132 companies·56 clinical trials

Drug Pipeline by Phase

Approved(103)

Drug	Company
acetaminophen	Spero Therapeutics, Inc. (SPRO)
acetaminophen	Mylan II B.V. (MYL)
acetaminophen	DR REDDYS LABORATORIES LTD (RDY)
acetaminophen	GT Biopharma, Inc. (GTBP)
adiavita	Adia Nutrition Inc. (ADIA)
almotriptan malate	Mylan II B.V. (MYL)
amitiza	SUCAMPO PHARMACEUTICALS, INC. (SCMP)
baclofen	Impax Laboratories, LLC (IPXL)
baclofen	ANI PHARMACEUTICALS INC (ANIP)
belbuca	BIODELIVERY SCIENCES INTERNATIONAL INC (BDSI)
Belbuca	COLLEGIUM PHARMACEUTICAL, INC (COLL)
bromfenac	Amneal Pharmaceuticals, Inc. (AMRX)
bromfenac	Aptinyx Inc. (APTX)
byqlovi	HARROW, INC. (IMMY)
caldolor	CUMBERLAND PHARMACEUTICALS INC (CPIX)
cannabis	One World Products, Inc. (OWPC)
celecoxib	AlphaTON Capital Corp (ATON)
celecoxib	Aptinyx Inc. (APTX)
celecoxib	ACADIA PHARMACEUTICALS INC (ACAD)
celecoxib	Miromatrix Medical Inc. (MIRO)
celecoxib	Zomedica Corp. (ZOMDF)
clobetasol propionate ophthalmic suspension 0.05%	HYPERION DEFI, INC. (HYPD)
coolief	Avanos Medical Inc. (AVNS)
Cymbalta®	ELI LILLY & Co (LLY)
dsuvia	Verrica Pharmaceuticals Inc. (VRCA)
dsuvia	XOMA Royalty Corporation (XOMA)
duloxetine	Inventiva S.A. (IVA)
EXPAREL	Pacira BioSciences, Inc. (PCRX)
galliprant	ARATANA THERAPEUTICS, INC. (PETX)
gloperba	SCILEX HOLDING CO (SCLX)
hydrocodone bi	AGENUS INC (AGEN)
hydrocodone bi	SUNSET ISLAND GROUP (SUN)
hydrocodone bi	ANI PHARMACEUTICALS INC (ANIP)
ibuprofen	AERIE PHARMACEUTICALS INC (AERI)
ibuprofen	CHINA PHARMA HOLDINGS, INC. (CPHI)
ibuprofen	DR REDDYS LABORATORIES LTD (RDY)
ibuprofen	PERRIGO Co plc (PRGO)
ibuprofen	GT Biopharma, Inc. (GTBP)
ibuprofen	PATHEON N.V. (PTI)
ibuprofen	SUNSET ISLAND GROUP (SUN)
ilevro	HARROW, INC. (IMMY)
imvexxy	TherapeuticsMD, Inc. (TXMD)
indocin	Zyla Life Sciences (ZCOR)
indocin	Assertio Holdings, Inc. (ASRT)
INDOCIN (suppositories and oral suspension)	Assertio Holdings, Inc. (ASRT)
INDOCIN Oral Suspension	Assertio Holdings, Inc. (ASRT)
Indometacin and Furazolidone Suppositories	China Health Industries Holdings, Inc. (CHHE)
indomethacin	Mylan II B.V. (MYL)
indomethacin	Amneal Pharmaceuticals, Inc. (AMRX)
Injury and Paralysis Tincture	China Health Industries Holdings, Inc. (CHHE)
iovera°	Pacira BioSciences, Inc. (PCRX)
iovera° system	Pacira BioSciences, Inc. (PCRX)
journavx	VERTEX PHARMACEUTICALS INC / MA (VRTX)
metastron	Q BioMed Inc. (QBIO)
methadone	ELITE PHARMACEUTICALS INC /NV/ (ELTP)
morphine	Impax Laboratories, LLC (IPXL)
morphine	SUNSET ISLAND GROUP (SUN)
muscle rub	QUANTA INC (QNTA)
Muskiness Pain Relieving Paste	China Health Industries Holdings, Inc. (CHHE)
MYOBLOC	SUPERNUS PHARMACEUTICALS, INC. (SUPN)
naloxone	Amneal Pharmaceuticals, Inc. (AMRX)
naproxen	Amneal Pharmaceuticals, Inc. (AMRX)
Nucynta ER	COLLEGIUM PHARMACEUTICAL, INC (COLL)
Nucynta ER and Nucynta IR	COLLEGIUM PHARMACEUTICAL, INC (COLL)
Nucynta IR	COLLEGIUM PHARMACEUTICAL, INC (COLL)
nyloxin	NUTRA PHARMA CORP (NPHC)
olinvyk	TREVENA INC (TRVN)
on-q	Avanos Medical Inc. (AVNS)
onsolis	BIODELIVERY SCIENCES INTERNATIONAL INC (BDSI)
onsolis/breakyl/painkyl	BIODELIVERY SCIENCES INTERNATIONAL INC (BDSI)
oxaydo	Zyla Life Sciences (ZCOR)
oxycodone	NULIFE SCIENCES, INC. (NULF)
oxycodone	Nascent Biotech Inc. (NBIO)
oxycodone	SUNSET ISLAND GROUP (SUN)
painshield md	ENvue Medical Inc. (FEED)
painshield plus	ENvue Medical Inc. (FEED)
pet pain-away	NUTRA PHARMA CORP (NPHC)
posimir	DURECT CORP (DRRX)
qdolo	Alterity Therapeutics Limited (ATHE)
Relistor	Bausch Health Companies Inc. (BHC)
sodium	Ginkgo Bioworks Holdings Inc. (DNA)
sofpulse	ENDONOVO THERAPEUTICS, INC. (ENDV)
sonalleve	Profound Medical Corp. (PROF)
sprix	Zyla Life Sciences (ZCOR)
SPRIX	Assertio Holdings, Inc. (ASRT)
strontium-89	Q BioMed Inc. (QBIO)
subsys	Insys Therapeutics, Inc. (INSY)
symproic	BIODELIVERY SCIENCES INTERNATIONAL INC (BDSI)
Symproic	COLLEGIUM PHARMACEUTICAL, INC (COLL)
tilidine	AOXING PHARMACEUTICAL COMPANY, INC. (AXN)
tramadol	Mylan II B.V. (MYL)
tramadol	Prestige Consumer Healthcare Inc. (PBH)
tramadol	SUNSET ISLAND GROUP (SUN)
tramadol	GH Research PLC (GHRS)
vazalore	PLX PHARMA INC. (DPRX)
venodol	SPOTLIGHT INNOVATION INC. (STLT)
venodol roll-on	SPOTLIGHT INNOVATION INC. (STLT)
vivlodex	Zyla Life Sciences (ZCOR)
zilretta	Flexion Therapeutics Inc (FLXN)
Zipsor	Assertio Holdings, Inc. (ASRT)
zohydro er with beadtek	PERNIX THERAPEUTICS HOLDINGS, INC. (PTX)
zorvolex	Zyla Life Sciences (ZCOR)
zynrelef	HERON THERAPEUTICS, INC. /DE/ (HRTX)

Phase 3(26)

Drug	Company
24-IU oxytocin	Valneva SE (VALN)
48-IU oxytocin	Valneva SE (VALN)
Apitox (Apitoxin in South Korea)	Apimeds Pharmaceuticals US, Inc. (APUS)
Bupivacaine	UNITED THERAPEUTICS Corp (UTHR)
bupivicaine hcl	HERON THERAPEUTICS, INC. /DE/ (HRTX)
buprenorphine sublingual spray	Insys Therapeutics, Inc. (INSY)
cingal	Anika Therapeutics Inc. (ANIK)
htx-002	HERON THERAPEUTICS, INC. /DE/ (HRTX)
htx-009	HERON THERAPEUTICS, INC. /DE/ (HRTX)
htx-011	HERON THERAPEUTICS, INC. /DE/ (HRTX)
htx-011a	HERON THERAPEUTICS, INC. /DE/ (HRTX)
htx-011b	HERON THERAPEUTICS, INC. /DE/ (HRTX)
Intravenous Oxytocin	Crinetics Pharmaceuticals, Inc. (CRNX)
Lidocaine	Merus N.V. (MRUS)
mr-107a-02	Viatris Inc (VTRS)
pf614	Ensysce Biosciences Inc. (ENSC)
pf614-mpar	Ensysce Biosciences Inc. (ENSC)
ranevetmab	Nexvet Biopharma plc (NVET)
semdexa	Sorrento Therapeutics, Inc. (SRNE)
sp-102	SEMNUR PHARMACEUTICALS, INC. (SMNR)
sp-102	SCILEX HOLDING CO (SCLX)
suz	VERTEX PHARMACEUTICALS INC / MA (VRTX)
tlc599	Endo International plc (ENDP)
xaracoll	INNOCOLL HOLDINGS PLC (INNL)
xen1120	Xenon Pharmaceuticals Inc. (XENE)
xen1701	Xenon Pharmaceuticals Inc. (XENE)

Phase 2(35)

Drug	Company
3,4-Methylenedioxymethamphetamine	AYTU BIOPHARMA, INC (AYTU)
3,4-Methylenedioxymethamphetamine	COLLEGIUM PHARMACEUTICAL, INC (COLL)
ACP-044 Dose A	ACADIA PHARMACEUTICALS INC (ACAD)
ACP-044 Dose B	ACADIA PHARMACEUTICALS INC (ACAD)
allostemspine	CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ)
Bupivacaine Hydrochloride	Pacira BioSciences, Inc. (PCRX)
bupivacaine liposome injectable suspension	Pacira BioSciences, Inc. (PCRX)
Capsaicin 8% Patch	Revance Therapeutics, Inc. (RVNC)
cemdomespib	REATA PHARMACEUTICALS INC (RETA)
cytora novel therapeutic	Zeo ScientifiX, Inc. (ZEOX)
dhea	GH Research PLC (GHRS)
frunevetmab	Nexvet Biopharma plc (NVET)
halneuron	Dogwood Therapeutics, Inc. (DWTX)
hb/apap	VERTEX PHARMACEUTICALS INC / MA (VRTX)
IncobotulinumtoxinA	Revance Therapeutics, Inc. (RVNC)
IW-3300	IRONWOOD PHARMACEUTICALS INC (IRWD)
lidopain	IMMUNE PHARMACEUTICALS INC (IMNP)
ly3848575	ELI LILLY & Co (LLY)
LY4065967	ELI LILLY & Co (LLY)
ly4515100	ELI LILLY & Co (LLY)
Methylphenidate	COLLEGIUM PHARMACEUTICAL, INC (COLL)
nyx-2925	Aptinyx Inc. (APTX)
ok-101 0.05%	OKYO Pharma Ltd (OKYO)
ok-101 0.1%	OKYO Pharma Ltd (OKYO)
olorinab	ARENA PHARMACEUTICALS INC (ARNA)
pilavapadin	LEXICON PHARMACEUTICALS, INC. (LXRX)
PIPE-307	Contineum Therapeutics, Inc. (CTNM)
PIPE-791	Contineum Therapeutics, Inc. (CTNM)
Platelet rich plasma	Revance Therapeutics, Inc. (RVNC)
pregnenolone	GH Research PLC (GHRS)
resiniferatoxin	Sorrento Therapeutics, Inc. (SRNE)
rta 901	BIOGEN INC. (BIIB)
rta 901	REATA PHARMACEUTICALS INC (RETA)
sp-103	SCILEX HOLDING CO (SCLX)
tilidine / naloxone	AOXING PHARMACEUTICAL COMPANY, INC. (AXN)

Phase 1(29)

Drug	Company
153sm-dotmp	Telix Pharmaceuticals Ltd (TLPPF)
153sm-dotmp	Telix Pharmaceuticals Limited (TLX)
AlloStemSpine® (CELZ-201 ADAPT)	CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ)
AlloStemSpine® Chronic Lower Back Pain (CELZ-201 ADAPT)	CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ)
AlloStem™ (CELZ-201-DDT)	CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ)
ap-cannabinoids	INTEC PHARMA LTD. (NTEC)
ART26.12	ARTELO BIOSCIENCES, INC. (ARTL)
cc8464	Pelthos Therapeutics Inc. (PTHS)
CELZ-001	CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ)
CELZ-201-DDT	CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ)
drsp/ee	VERTEX PHARMACEUTICALS INC / MA (VRTX)
egalet-004	Zyla Life Sciences (ZCOR)
fx301	Flexion Therapeutics Inc (FLXN)
intrathecal resiniferatoxin	GH Research PLC (GHRS)
intrathecal resiniferatoxin	National Research Corporation Common Stock (Delaware) (NRC)
ketamir-2	MIRA PHARMACEUTICALS, INC. (MIRA)
kindolor	GH Research PLC (GHRS)
Lidocaine + Tetracaine	Merus N.V. (MRUS)
ngm/ee	VERTEX PHARMACEUTICALS INC / MA (VRTX)
Paracetamol	PROTHENA CORP PUBLIC LTD CO (PRTA)
Paracetamol	ARROWHEAD PHARMACEUTICALS, INC. (ARWR)
pl1100	PLX PHARMA INC. (DPRX)
pl1200	PLX PHARMA INC. (DPRX)
prana bio nutrient medicinals p1	UNITED CANNABIS CORP (CNAB)
trv734	TREVENA INC (TRVN)
vx-150	VERTEX PHARMACEUTICALS INC / MA (VRTX)
vx-548	VERTEX PHARMACEUTICALS INC / MA (VRTX)
vx-973	VERTEX PHARMACEUTICALS INC / MA (VRTX)
vx-993	VERTEX PHARMACEUTICALS INC / MA (VRTX)

Preclinical(46)

Drug	Company
activated cannabinoid	Phoenix Life Sciences International Limited. (PLSI)
AR-300	Ampio Pharmaceuticals, Inc. (AMPE)
at-003	ARATANA THERAPEUTICS, INC. (PETX)
at-019	ARATANA THERAPEUTICS, INC. (PETX)
autonomix system	Autonomix Medical Inc. (AMIX)
basivertebral nerve ablation system	NeuroOne Medical Technologies Corporation (NMTC)
cannabis based wafer	CTT PHARMACEUTICAL HOLDINGS, INC. (CTTH)
Cannabis Genomic Study	WEED, INC. (BUDZ)
cannabis-derived products	One World Products, Inc. (OWPC)
celz-100	CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ)
ct2000	Pelthos Therapeutics Inc. (PTHS)
ct3000	Pelthos Therapeutics Inc. (PTHS)
egalet-002	Zyla Life Sciences (ZCOR)
envelta	Virpax Pharmaceuticals, Inc. (VRPX)
epoladerm	Virpax Pharmaceuticals, Inc. (VRPX)
feldetrex	PREMIER BIOMEDICAL INC (BIEI)
green meadow pr formula	Optec International, Inc. (GM)
ImmCelz™ (CELZ-100)	CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ)
jan123	ALT5 Sigma Corp (ALTS)
joint pain/arthritis formulation	HEALTH-RIGHT DISCOVERIES, INC. (HRDV)
kv7 development candidates	Xenon Pharmaceuticals Inc. (XENE)
low dose naltrexone	Biostax Corp. (BTAX)
medi-strip relaxation	Phoenix Life Sciences International Limited. (PLSI)
nav1.7 lead candidate	Xenon Pharmaceuticals Inc. (XENE)
nhāler	Rapid Therapeutic Science Laboratories, Inc. (RTSL)
novel pain management product	PHIBRO ANIMAL HEALTH CORP (PAHC)
nv-03	Nexvet Biopharma plc (NVET)
oradisc b	ULURU INC. (ULU)
patient pure x	Zeo ScientifiX, Inc. (ZEOX)
prana bio nutrient medicinals	UNITED CANNABIS CORP (CNAB)
probudur	Virpax Pharmaceuticals, Inc. (VRPX)
prtt-200	PROTECT PHARMACEUTICAL CORP (PRTT)
prtt-300	PROTECT PHARMACEUTICAL CORP (PRTT)
recet	NUTRA PHARMA CORP (NPHC)
rpi-70	NUTRA PHARMA CORP (NPHC)
rpi-78	NUTRA PHARMA CORP (NPHC)
sequestox	ELITE PHARMACEUTICALS INC /NV/ (ELTP)
SP-26	Silo Pharma, Inc. (SILO)
spinal cord stimulation system	NeuroOne Medical Technologies Corporation (NMTC)
supera-cbd	Q/C TECHNOLOGIES, INC. (QCLS)
talismann	Bioventus Inc. (BVS)
talismann pulse generator	Bioventus Inc. (BVS)
trv045	TREVENA INC (TRVN)
undisclosed pain program	Korro Bio, Inc. (KRRO)
uroshield	ENvue Medical Inc. (FEED)
uroshield ultra	ENvue Medical Inc. (FEED)

Unknown(9)

Drug	Company
Brufen™	ABBOTT LABORATORIES (ABT)
Cannabis Genomic Study (Sangre AT, LLC)	WEED, INC. (BUDZ)
cbdessence	FUTUREWORLD CORP. (FWDG)
dario move	DarioHealth Corp. (DRIO)
magnesium	GH Research PLC (GHRS)
nb-01	MetaVia Inc. (MTVA)
Pain Cream 850mg (Broad Spectrum topical)	Charlie's Holdings, Inc. (CHUC)
PluriPain-PMS	BIOADAPTIVES, INC. (BDPT)
PluriPain®	BIOADAPTIVES, INC. (BDPT)

Early Phase 1(8)

Drug	Company
1200mg Cannabidiol	COLLEGIUM PHARMACEUTICAL, INC (COLL)
400mg Cannabidiol	COLLEGIUM PHARMACEUTICAL, INC (COLL)
800mg Cannabidiol	COLLEGIUM PHARMACEUTICAL, INC (COLL)
Duloxetine- Acetaminophen	Cidara Therapeutics, Inc. (CDTX)
Duloxetine- Acetaminophen	Structure Therapeutics Inc. (GPCR)
Lidocaine and Ketamine Infusion	Crinetics Pharmaceuticals, Inc. (CRNX)
Pregabalin- Acetaminophen	Cidara Therapeutics, Inc. (CDTX)
Pregabalin- Acetaminophen	Structure Therapeutics Inc. (GPCR)

N/A(6)

Drug	Company
Local anesthetic	UNITED THERAPEUTICS Corp (UTHR)
Methylphenidate	AYTU BIOPHARMA, INC (AYTU)
Paracetamol	Cidara Therapeutics, Inc. (CDTX)
Paracetamol	Structure Therapeutics Inc. (GPCR)
Prilocaine HCl % 2 injectable solution	Revance Therapeutics, Inc. (RVNC)
StemSpine®	CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ)

Phase 1/Phase 2(1)

Drug	Company
ST-503	SANGAMO THERAPEUTICS, INC (SGMO)

Phase 2/Phase 3(1)

Drug	Company
ath-1020	LeonaBio, Inc. (LONA)

Phase 4(29)

Drug	Company
Acetaminophen 500Mg Tab	Cidara Therapeutics, Inc. (CDTX)
Acetaminophen 500Mg Tab	Structure Therapeutics Inc. (GPCR)
Acetaminophen 500Mg Tab	Filana Therapeutics Inc. (FLNA)
Acetazolamide 500 MG Extended Release Oral Capsule	Valneva SE (VALN)
Botulinum toxin injection	Revance Therapeutics, Inc. (RVNC)
Dexmedetomidine	COGNITION THERAPEUTICS INC (CGTX)
Diclofenac	Assertio Holdings, Inc. (ASRT)
Diclofenac	Crinetics Pharmaceuticals, Inc. (CRNX)
Diclofenac	Cidara Therapeutics, Inc. (CDTX)
Diclofenac	ARROWHEAD PHARMACEUTICALS, INC. (ARWR)
Diclofenac	PROTHENA CORP PUBLIC LTD CO (PRTA)
Diclofenac	Filana Therapeutics Inc. (FLNA)
Diclofenac	Structure Therapeutics Inc. (GPCR)
Duloxetine- Acetaminophen	Filana Therapeutics Inc. (FLNA)
Group O	COLLEGIUM PHARMACEUTICAL, INC (COLL)
Ibuprofen 200Mg Oral Tablet	PROTHENA CORP PUBLIC LTD CO (PRTA)
Ibuprofen 200Mg Oral Tablet	Cidara Therapeutics, Inc. (CDTX)
Ibuprofen 200Mg Oral Tablet	Filana Therapeutics Inc. (FLNA)
Ibuprofen 200Mg Oral Tablet	Structure Therapeutics Inc. (GPCR)
Morphine	COGNITION THERAPEUTICS INC (CGTX)
Onabotulinum toxin A	Revance Therapeutics, Inc. (RVNC)
Paracetamol	Filana Therapeutics Inc. (FLNA)
Pregabalin- Acetaminophen	Filana Therapeutics Inc. (FLNA)
Tegileridine	COGNITION THERAPEUTICS INC (CGTX)
Tramadol	Crinetics Pharmaceuticals, Inc. (CRNX)
Tramadol	Assertio Holdings, Inc. (ASRT)
Tramadol	ARROWHEAD PHARMACEUTICALS, INC. (ARWR)
Tramadol	PROTHENA CORP PUBLIC LTD CO (PRTA)
Tramadol	Structure Therapeutics Inc. (GPCR)

Compare drugs

acetaminophen vs adiavita acetaminophen vs almotriptan malate acetaminophen vs amitiza

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How many drugs are in development for Pain?

BioSniper tracks 293 drugs in development for Pain across 132 companies.

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There are 56 clinical trials targeting Pain tracked by BioSniper.

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