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epinephrine

Generic: EPINEPHRINE·Brand: ADRENACLICK, ADRENALIN, AUVI-Q, Adrenalin, Articadent, Auvi-Q, BRONKAID MIST, Citanest Forte, EPI E Z PEN JR, EPINEPHRINE, EPINEPHRINE (AUTOINJECTOR), EPIPEN, EPIPEN E Z PEN, EPIPEN JR., Epipen, Lignospan, Marcaine with Epinephrine, NEFFY, Neffy, Orabloc, PRIMATENE MIST, Primatene Mist Inhaler, SUS-PHRINE SULFITE FREE, SYMJEPI, Sensorcaine with Epinephrine, Septocaine, Symjepi, TWINJECT, Ultacan, Vivacaine, Xylocaine with Epinephrine, Zorcaine

epinephrine: 9 clinical trials tracked.

epinephrine evidence translation

What we can confirm

9 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about epinephrine, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence7 indications · 2 study sponsors
Clinical Trial Registry Records (9)

A Phase 2, Open-label Clinical Study to Evaluate the Safety and Efficacy of MK-2010 as Monotherapy and in Combination

NCT07793942Registry updated 2026-10-08·Phase 2
Not yet recruiting

Primary endpoint: Number of Participants with Adverse Events (AEs)

Interventionalopen480 targetStarted 2026-10Completion 2030-076 sites · Switzerland, United StatesMerck Sharp & Dohme LLC

Phase 2, Open-Label Study to Evaluate the Safety and Efficacy of MK-2010 in Combination With Sacituzumab Tirumotecan (Sac-TMT) in Participants With Advanced Solid Tumors

NCT07785609Registry updated 2026-10-09·Phase 2
Recruiting

Primary endpoint: Number of Participants Who Experience an Adverse Event (AE)

Interventionalopen200 targetStarted 2026-10Completion 2031-094 sites · Hong Kong, Switzerland, United StatesMerck Sharp & Dohme LLC

Efficacy of Ropivacaine Epinephrine Clonidine Ketorolac (R.E.C.K) vs Exparel in Robotic Nephrectomy: a Randomized, Prospective Trial

NCT07092566Registry updated 2026-07-13·Phase 3
Recruiting

Primary endpoint: Area Under the Curve (AUC) of the Numeric Rating Scale (NRS) pain intensity scores through 7 days (168 hours) for participants receiving Exparel vs. R.E.C.K.

InterventionalRandomizedopen170 targetStarted 2025-11Completion 2027-101 site · United StatesWake Forest University Health Sciences

An Outpatient, Randomized, Double-Blinded, Placebo-Controlled, Cross-Over Study of the Efficacy of ARS-2 in Patients With Chronic Spontaneous Urticaria

NCT06927999Registry updated 2026-09-16·Phase 2·SPRY
Recruiting

Primary endpoint: Determine the effect of ARS-2 (0.5 mg or 1 mg) versus placebo on itch

InterventionalRandomizeddouble42 targetStarted 2025-07Completion 2027-063 sites · Germany, United StatesARS Pharmaceuticals, Inc.

A Randomized Controlled Trial of Bupivacaine With Epinephrine for Local Pain Control Following Perineal Laceration Repair in Patients With Pre-existing Epidural Analgesia: The PAIN Trial

NCT05972681Registry updated 2026-05-27·Phase 4
Terminated

Primary endpoint: Time to First Analgesic

InterventionalRandomizedquadruple3 targetStarted 2025-04Completion 2025-101 site · United StatesMontefiore Medical Center

A 2-Part, Phase 2, Open-Label, Randomized, Fixed Sequence Study to Evaluate the Pharmacokinetics and Pharmacodynamics of Epinephrine After Single and Repeat Doses of DESF in Healthy Adults With Oral Allergy Syndrome (OASIS: Oral Anaphylm Symptom Intervention Study)

NCT06527937Registry updated 2025-09-26·Phase 2·AQST
Completed

Primary endpoint: Cmax

InterventionalRandomizedopen36 enrolledStarted 2024-07Completion 2024-101 site · United StatesAquestive Therapeutics

Multimodal Nonopioid Pain Protocol Following Shoulder Arthroplasty Surgery

NCT05488847Registry updated 2026-02-10·Phase 4
Active, not recruiting

Primary endpoint: Pain Levels

InterventionalRandomizedsingle83 targetStarted 2022-06Completion 2026-091 site · United StatesHenry Ford Health System

Intracoronary Administration of Epinephrine and Verapamil in the Refractory No-reflow Phenomenon in Patients With Acute Myocardial Infarction: The EPIVER Randomized Controlled Trial

NCT04573751Registry updated 2026-06-24·N/A
Completed

Primary endpoint: Mortality

InterventionalRandomizedopen104 enrolledStarted 2020-12Completion 2024-011 site · RussiaTomsk National Research Medical Center of the Russian Academy of Sciences

Phase I/II Trial of HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PD-L1/TGF-Beta Trap (M7824) in Subjects With HPV Positive Cancers

NCT04432597Registry updated 2026-02-17·Phase 1
Active, not recruiting

Primary endpoint: Safety and recommended phase II dose of PRGN-2009

Interventionalopen39 targetStarted 2020-08Completion 2026-031 site · United StatesNational Cancer Institute (NCI)