| GILDGILEAD SCIENCES, INC. | 2,161,094 | $301.2M |
| INCYIncyte Corp. | 1,742,870 | $164.0M |
| REGNREGENERON PHARMACEUTICALS, INC. | 129,074 | $99.7M |
| SNYSanofi | 1,830,115 | $88.1M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 195,937 | $64.8M |
| INSMINSMED Inc | 396,245 | $64.8M |
| LGNDLigand Pharmaceuticals Incorporated | 303,224 | $60.5M |
| TEVATeva Pharmaceutical Industries Limited | 1,838,437 | $55.4M |
| JAZZJazz Pharmaceuticals plc | 256,598 | $48.5M |
| PCVXVaxcyte, Inc. | 501,857 | $29.2M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 502,406 | $26.0M |
| KNSAKiniksa Pharmaceuticals International, plc | 506,521 | $24.4M |
| ARGXARGENX SE | 32,255 | $23.6M |
| EXELEXELIXIS, INC. | 513,331 | $22.0M |
| BBIOBridgeBio Pharma, Inc. | 254,007 | $18.9M |
| SYRESpyre Therapeutics, Inc. | 292,126 | $14.7M |
| RVMDREVOLUTION MEDICINES, INC. | 142,578 | $13.9M |
| INVAInnoviva, Inc. | 523,415 | $12.2M |
| PTGXProtagonist Therapeutics, Inc | 83,544 | $8.8M |
| IONSIONIS PHARMACEUTICALS INC | 108,744 | $8.2M |
| APGEApogee Therapeutics, Inc. | 95,137 | $8.0M |
| ANIPANI PHARMACEUTICALS INC | 100,565 | $7.7M |
| ANABANAPTYSBIO, INC | 108,203 | $6.0M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 103,161 | $5.8M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 89,286 | $5.6M |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 172,663 | $5.5M |
| ADPTAdaptive Biotechnologies Corp | 390,855 | $5.4M |
| ORICOric Pharmaceuticals, Inc. | 405,280 | $5.1M |
| TGTXTG THERAPEUTICS, INC. | 147,975 | $4.9M |
| ROIVRoivant Sciences Ltd. | 171,500 | $4.8M |
| COGTCogent Biosciences, Inc. | 109,419 | $4.2M |
| LQDALiquidia Corp | 98,357 | $3.7M |
| VRDNViridian Therapeutics, Inc.\DE | 188,177 | $3.7M |
| TERNTerns Pharmaceuticals, Inc. | 63,471 | $3.3M |
| TVTXTravere Therapeutics, Inc. | 111,633 | $3.3M |
| ACADACADIA PHARMACEUTICALS INC | 143,469 | $3.2M |
| OLMAOlema Pharmaceuticals, Inc. | 203,959 | $3.0M |
| OGNOrganon & Co. | 485,509 | $2.9M |
| MRNAModerna, Inc. | 53,802 | $2.7M |
| SIGASIGA TECHNOLOGIES INC | 376,571 | $2.0M |
| IRONDisc Medicine, Inc. | 29,218 | $1.9M |
| PTCTPTC THERAPEUTICS, INC. | 27,253 | $1.9M |
| ALMSALUMIS INC. | 82,654 | $1.8M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 20,504 | $1.8M |
| KODKodiak Sciences Inc. | 37,638 | $1.4M |
| ARQTArcutis Biotherapeutics, Inc. | 60,402 | $1.4M |
| PVLAPALVELLA THERAPEUTICS, INC. | 11,403 | $1.4M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 15,662 | $1.3M |
| SRRKScholar Rock Holding Corp | 25,870 | $1.3M |
| CYTKCYTOKINETICS INC | 19,278 | $1.3M |
| TNGXTango Therapeutics, Inc. | 52,801 | $1.1M |
| STOKStoke Therapeutics, Inc. | 33,890 | $1.1M |
| ZYMEZymeworks Inc. | 42,404 | $1.1M |
| NUVLNuvalent, Inc. | 9,428 | $966K |
| NRIXNurix Therapeutics, Inc. | 61,774 | $957K |
| CLDXCelldex Therapeutics, Inc. | 27,422 | $870K |
| AXSMAxsome Therapeutics, Inc. | 4,917 | $831K |
| NTLAIntellia Therapeutics, Inc. | 62,509 | $801K |
| APLSApellis Pharmaceuticals, Inc. | 19,817 | $797K |
| PGENPRECIGEN, INC. | 202,682 | $784K |
| BEAMBeam Therapeutics Inc. | 31,099 | $741K |
| VCELVericel Corp | 22,067 | $710K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 19,115 | $647K |
| ANNXAnnexon, Inc. | 115,527 | $640K |
| ADMAADMA BIOLOGICS, INC. | 67,812 | $611K |
| FOLDAMICUS THERAPEUTICS, INC. | 35,447 | $513K |
| ZVRAZEVRA THERAPEUTICS, INC. | 54,251 | $506K |
| ABSIAbsci Corporation | 150,999 | $453K |
| VKTXViking Therapeutics, Inc. | 12,846 | $418K |
| CAMPCamp4 Therapeutics Corp | 82,450 | $364K |
| IBRXImmunityBio, Inc. | 42,762 | $328K |
| DNLIDenali Therapeutics Inc. | 16,194 | $311K |
| RCUSArcus Biosciences, Inc. | 13,513 | $292K |
| IMVTImmunovant, Inc. | 9,614 | $239K |
| UPBUpstream Bio, Inc. | 25,866 | $233K |
| ORKAOruka Therapeutics, Inc. | 4,678 | $229K |
| NKTRNEKTAR THERAPEUTICS | 3,127 | $225K |
| BCAXBicara Therapeutics Inc. | 10,070 | $200K |
| OCULOCULAR THERAPEUTIX, INC | 22,528 | $191K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 53,269 | $164K |
| ARDXARDELYX, INC. | 26,885 | $161K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 40,463 | $142K |
| ARVNARVINAS, INC. | 13,200 | $140K |
| BHVNBiohaven Ltd. | 14,578 | $123K |
| NUVBNuvation Bio Inc. | 27,882 | $120K |
| XERSXeris Biopharma Holdings, Inc. | 18,331 | $106K |
| GERNGERON CORP | 69,578 | $104K |
| ESPREsperion Therapeutics, Inc. | 28,207 | $77K |
| CMPXCompass Therapeutics, Inc. | 13,729 | $73K |
| CTMXCytomX Therapeutics, Inc. | 15,161 | $71K |
| SLSSELLAS Life Sciences Group, Inc. | 16,048 | $68K |
| OCGNOcugen, Inc. | 36,556 | $66K |
| SVRASavara Inc | 11,914 | $65K |
| SANASana Biotechnology, Inc. | 19,022 | $55K |
| AQSTAquestive Therapeutics, Inc. | 13,177 | $55K |
| OPKOPKO HEALTH, INC. | 44,268 | $50K |
| ALTAltimmune, Inc. | 14,763 | $45K |
| CATXPerspective Therapeutics, Inc. | 10,567 | $44K |
| LCTXLineage Cell Therapeutics, Inc. | 26,921 | $43K |
| RCKTRocket Pharmaceuticals Inc. | 11,558 | $41K |
| LXRXLEXICON PHARMACEUTICALS, INC. | 22,679 | $35K |
| IVVDInvivyd, Inc. | 25,703 | $33K |
| AVXLANAVEX LIFE SCIENCES CORP. | 10,275 | $32K |
| OVIDOvid Therapeutics Inc. | 13,166 | $29K |
| CHRSCoherus Oncology, Inc. | 14,118 | $24K |
| PROKPROKIDNEY CORP. | 11,828 | $21K |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 21,233 | $17K |
| FATEFATE THERAPEUTICS INC | 12,595 | $15K |
| HUMAHumacyte Inc. | 18,758 | $11K |
| SGMOQSANGAMO THERAPEUTICS, INC | 42,040 | $10K |