| GILDGILEAD SCIENCES, INC. | 213,031 | $29.7M |
| REGNREGENERON PHARMACEUTICALS, INC. | 12,633 | $9.8M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 88,908 | $4.9M |
| RDYDR REDDYS LABORATORIES LTD | 336,578 | $4.7M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 12,215 | $4.0M |
| INCYIncyte Corp. | 32,067 | $3.0M |
| SNYSanofi | 57,771 | $2.8M |
| ARGXARGENX SE | 3,136 | $2.3M |
| MRNAModerna, Inc. | 43,461 | $2.2M |
| INSMINSMED Inc | 11,210 | $1.8M |
| PCVXVaxcyte, Inc. | 30,004 | $1.7M |
| EXELEXELIXIS, INC. | 40,544 | $1.7M |
| CYTKCYTOKINETICS INC | 23,835 | $1.6M |
| GMABGenmab A/S | 57,292 | $1.5M |
| RVMDREVOLUTION MEDICINES, INC. | 14,497 | $1.4M |
| BBIOBridgeBio Pharma, Inc. | 18,966 | $1.4M |
| ROIVRoivant Sciences Ltd. | 47,876 | $1.3M |
| TERNTerns Pharmaceuticals, Inc. | 22,676 | $1.2M |
| JAZZJazz Pharmaceuticals plc | 5,427 | $1.0M |
| TEVATeva Pharmaceutical Industries Limited | 33,705 | $1.0M |
| ONCBeOne Medicines Ltd. | 3,181 | $945K |
| IONSIONIS PHARMACEUTICALS INC | 11,414 | $857K |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 12,230 | $767K |
| NUVLNuvalent, Inc. | 7,145 | $732K |
| BMRNBIOMARIN PHARMACEUTICAL INC | 12,550 | $709K |
| PTGXProtagonist Therapeutics, Inc | 5,672 | $598K |
| KODKodiak Sciences Inc. | 14,987 | $571K |
| FOLDAMICUS THERAPEUTICS, INC. | 36,983 | $535K |
| AXSMAxsome Therapeutics, Inc. | 2,968 | $502K |
| PTCTPTC THERAPEUTICS, INC. | 7,318 | $499K |
| ADPTAdaptive Biotechnologies Corp | 35,454 | $492K |
| TNGXTango Therapeutics, Inc. | 23,517 | $492K |
| TGTXTG THERAPEUTICS, INC. | 14,153 | $470K |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 9,084 | $470K |
| VKTXViking Therapeutics, Inc. | 14,045 | $457K |
| IMTXImmatics N.V. | 44,890 | $442K |
| LGNDLigand Pharmaceuticals Incorporated | 2,162 | $432K |
| SRRKScholar Rock Holding Corp | 8,617 | $424K |
| COGTCogent Biosciences, Inc. | 8,459 | $326K |
| TLXTelix Pharmaceuticals Limited | 33,253 | $318K |
| RLAYRelay Therapeutics, Inc. | 31,582 | $314K |
| HCMHUTCHMED (China) Limited | 20,425 | $306K |
| INVAInnoviva, Inc. | 11,741 | $274K |
| ACADACADIA PHARMACEUTICALS INC | 12,265 | $273K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 3,102 | $270K |
| NKTRNEKTAR THERAPEUTICS | 3,685 | $265K |
| APGEApogee Therapeutics, Inc. | 2,863 | $241K |
| BEAMBeam Therapeutics Inc. | 9,910 | $236K |
| RCUSArcus Biosciences, Inc. | 10,773 | $233K |
| ALMSALUMIS INC. | 10,420 | $230K |
| DNLIDenali Therapeutics Inc. | 11,622 | $223K |
| SYRESpyre Therapeutics, Inc. | 4,397 | $222K |
| IBRXImmunityBio, Inc. | 28,717 | $220K |
| OGNOrganon & Co. | 36,396 | $218K |
| MESOMesoblast Limited | 14,009 | $215K |
| VCELVericel Corp | 6,287 | $202K |
| IMVTImmunovant, Inc. | 8,100 | $201K |
| QUREuniQure N.V. | 11,636 | $190K |
| NUVBNuvation Bio Inc. | 34,823 | $149K |
| NTLAIntellia Therapeutics, Inc. | 11,245 | $144K |
| CTMXCytomX Therapeutics, Inc. | 26,765 | $126K |
| PGENPRECIGEN, INC. | 30,013 | $116K |
| ALECAlector, Inc. | 50,629 | $109K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 29,804 | $105K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 33,864 | $104K |
| ADMAADMA BIOLOGICS, INC. | 11,093 | $100K |
| RCKTRocket Pharmaceuticals Inc. | 25,732 | $92K |
| LXRXLEXICON PHARMACEUTICALS, INC. | 54,965 | $86K |
| SIGASIGA TECHNOLOGIES INC | 15,868 | $85K |
| GERNGERON CORP | 55,891 | $83K |
| SLDBSolid Biosciences Inc. | 11,103 | $80K |
| CLYMClimb Bio, Inc. | 11,204 | $77K |
| ANNXAnnexon, Inc. | 12,936 | $72K |
| VYGRVoyager Therapeutics, Inc. | 18,268 | $71K |
| ARDXARDELYX, INC. | 10,810 | $65K |
| SANASana Biotechnology, Inc. | 21,632 | $62K |
| AGENAGENUS INC | 18,372 | $61K |
| FATEFATE THERAPEUTICS INC | 50,024 | $60K |
| CHRSCoherus Oncology, Inc. | 33,406 | $56K |
| SGMTSagimet Biosciences Inc. | 10,454 | $55K |
| OCGNOcugen, Inc. | 28,811 | $52K |
| IVVDInvivyd, Inc. | 39,309 | $51K |
| EVOEvotec SE | 20,115 | $50K |
| LRMRLarimar Therapeutics, Inc. | 11,142 | $50K |
| ABCLAbCellera Biologics Inc. | 13,988 | $49K |
| XFORX4 Pharmaceuticals, Inc | 11,525 | $48K |
| ABUSArbutus Biopharma Corp | 10,555 | $47K |
| CCCCC4 Therapeutics, Inc. | 15,249 | $40K |
| ABSIAbsci Corporation | 12,252 | $37K |
| ESPREsperion Therapeutics, Inc. | 12,181 | $33K |
| PRQRProQR Therapeutics N.V. | 19,410 | $31K |
| ALTAltimmune, Inc. | 10,127 | $31K |
| MENSJyong Biotech Ltd. | 13,927 | $30K |
| FLNAFilana Therapeutics Inc. | 13,891 | $23K |
| BDTXBlack Diamond Therapeutics, Inc. | 10,380 | $22K |
| BMEABiomea Fusion, Inc. | 13,703 | $21K |
| AUTLAutolus Therapeutics plc | 14,116 | $19K |
| QNCXQuince Therapeutics, Inc. | 132,661 | $13K |
| OPKOPKO HEALTH, INC. | 11,596 | $13K |
| PLRXPLIANT THERAPEUTICS, INC. | 10,029 | $13K |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 13,428 | $11K |
| HUMAHumacyte Inc. | 16,442 | $10K |
| CGTXCOGNITION THERAPEUTICS INC | 11,034 | $8K |
| SGMOQSANGAMO THERAPEUTICS, INC | 32,433 | $8K |
| OTLKOutlook Therapeutics, Inc. | 31,492 | $6K |
| LIMNLIMINATUS PHARMA, INC. | 34,706 | $6K |