| GILDGILEAD SCIENCES, INC. | 618,957 | $86.3M |
| REGNREGENERON PHARMACEUTICALS, INC. | 51,305 | $39.6M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 65,810 | $21.8M |
| INSMINSMED Inc | 105,805 | $17.3M |
| TEVATeva Pharmaceutical Industries Limited | 532,782 | $16.0M |
| INCYIncyte Corp. | 82,818 | $7.8M |
| RVMDREVOLUTION MEDICINES, INC. | 67,421 | $6.6M |
| MRNAModerna, Inc. | 89,128 | $4.5M |
| IONSIONIS PHARMACEUTICALS INC | 38,557 | $2.9M |
| EXELEXELIXIS, INC. | 64,574 | $2.8M |
| BBIOBridgeBio Pharma, Inc. | 36,591 | $2.7M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 46,848 | $2.6M |
| ROIVRoivant Sciences Ltd. | 95,251 | $2.6M |
| JAZZJazz Pharmaceuticals plc | 13,716 | $2.6M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 30,828 | $1.9M |
| CYTKCYTOKINETICS INC | 28,963 | $1.9M |
| PCVXVaxcyte, Inc. | 29,942 | $1.7M |
| AXSMAxsome Therapeutics, Inc. | 8,612 | $1.5M |
| TGTXTG THERAPEUTICS, INC. | 38,808 | $1.3M |
| PTGXProtagonist Therapeutics, Inc | 12,130 | $1.3M |
| PTCTPTC THERAPEUTICS, INC. | 18,397 | $1.3M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 13,927 | $1.2M |
| NUVLNuvalent, Inc. | 9,933 | $1.0M |
| FOLDAMICUS THERAPEUTICS, INC. | 67,496 | $976K |
| LGNDLigand Pharmaceuticals Incorporated | 4,802 | $959K |
| VKTXViking Therapeutics, Inc. | 26,096 | $849K |
| APGEApogee Therapeutics, Inc. | 9,647 | $812K |
| COGTCogent Biosciences, Inc. | 20,444 | $787K |
| APLSApellis Pharmaceuticals, Inc. | 19,240 | $774K |
| SRRKScholar Rock Holding Corp | 15,713 | $772K |
| TERNTerns Pharmaceuticals, Inc. | 14,604 | $770K |
| DNTHDianthus Therapeutics, Inc. /DE/ | 8,756 | $735K |
| DNLIDenali Therapeutics Inc. | 37,410 | $718K |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 13,668 | $706K |
| ARQTArcutis Biotherapeutics, Inc. | 28,101 | $662K |
| IBRXImmunityBio, Inc. | 85,610 | $657K |
| SYRESpyre Therapeutics, Inc. | 12,813 | $646K |
| ACADACADIA PHARMACEUTICALS INC | 28,667 | $638K |
| TVTXTravere Therapeutics, Inc. | 20,531 | $610K |
| LQDALiquidia Corp | 15,225 | $575K |
| BEAMBeam Therapeutics Inc. | 23,213 | $553K |
| IMVTImmunovant, Inc. | 21,412 | $532K |
| ADMAADMA BIOLOGICS, INC. | 58,417 | $526K |
| RCUSArcus Biosciences, Inc. | 21,207 | $458K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 13,537 | $458K |
| NKTRNEKTAR THERAPEUTICS | 6,355 | $457K |
| CLDXCelldex Therapeutics, Inc. | 14,345 | $455K |
| KNSAKiniksa Pharmaceuticals International, plc | 9,273 | $446K |
| INVAInnoviva, Inc. | 19,001 | $443K |
| DAWNDay One Biopharmaceuticals, Inc. | 18,569 | $398K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 12,969 | $394K |
| OGNOrganon & Co. | 64,743 | $388K |
| DFTXDefinium Therapeutics Inc. | 20,467 | $387K |
| SLNOSOLENO THERAPEUTICS INC | 11,508 | $385K |
| IRONDisc Medicine, Inc. | 5,959 | $381K |
| ADPTAdaptive Biotechnologies Corp | 26,656 | $370K |
| VCELVericel Corp | 11,380 | $366K |
| ARDXARDELYX, INC. | 61,084 | $366K |
| NTLAIntellia Therapeutics, Inc. | 28,471 | $365K |
| ALMSALUMIS INC. | 16,272 | $358K |
| ANIPANI PHARMACEUTICALS INC | 4,472 | $344K |
| STOKStoke Therapeutics, Inc. | 10,186 | $332K |
| PVLAPALVELLA THERAPEUTICS, INC. | 2,586 | $322K |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 10,027 | $321K |
| OCULOCULAR THERAPEUTIX, INC | 37,615 | $319K |
| VRDNViridian Therapeutics, Inc.\DE | 16,170 | $316K |
| KODKodiak Sciences Inc. | 8,200 | $313K |
| BHVNBiohaven Ltd. | 36,803 | $311K |
| NRIXNurix Therapeutics, Inc. | 20,000 | $310K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 98,823 | $303K |
| RLAYRelay Therapeutics, Inc. | 30,117 | $300K |
| ORKAOruka Therapeutics, Inc. | 5,839 | $286K |
| ELVNEnliven Therapeutics, Inc. | 7,153 | $280K |
| HROWHARROW, INC. | 7,864 | $277K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 76,944 | $270K |
| TNGXTango Therapeutics, Inc. | 12,235 | $256K |
| NUVBNuvation Bio Inc. | 58,889 | $253K |
| XERSXeris Biopharma Holdings, Inc. | 40,202 | $233K |
| ZYMEZymeworks Inc. | 8,803 | $220K |
| KURAKura Oncology, Inc. | 25,474 | $207K |
| ANABANAPTYSBIO, INC | 3,575 | $198K |
| ANNXAnnexon, Inc. | 35,034 | $194K |
| GERNGERON CORP | 123,888 | $185K |
| PGENPRECIGEN, INC. | 45,834 | $177K |
| CMPXCompass Therapeutics, Inc. | 33,422 | $177K |
| KALVKalVista Pharmaceuticals, Inc. | 8,650 | $174K |
| CTMXCytomX Therapeutics, Inc. | 36,925 | $174K |
| PHVSPharvaris N.V. | 6,089 | $172K |
| ARVNARVINAS, INC. | 15,727 | $167K |
| MLTXMoonLake Immunotherapeutics | 8,935 | $167K |
| ATAIAtai Beckley N.V. | 43,091 | $153K |
| QUREuniQure N.V. | 9,190 | $150K |
| OLMAOlema Pharmaceuticals, Inc. | 10,012 | $149K |
| BCAXBicara Therapeutics Inc. | 7,427 | $148K |
| ABUSArbutus Biopharma Corp | 31,288 | $141K |
| ORICOric Pharmaceuticals, Inc. | 10,680 | $135K |
| SVRASavara Inc | 23,460 | $128K |
| OPKOPKO HEALTH, INC. | 110,958 | $126K |
| SANASana Biotechnology, Inc. | 37,523 | $108K |
| CGEMCullinan Therapeutics, Inc. | 7,272 | $103K |
| PLSEPulse Biosciences Inc Common Stock (DE) | 3,995 | $86K |
| FLGTFulgent Genetics Inc. | 5,355 | $85K |
| SPRYARS Pharmaceuticals, Inc. | 10,600 | $85K |
| ZBIOZenas BioPharma, Inc. | 4,199 | $82K |
| UPBUpstream Bio, Inc. | 4,096 | $37K |
| DNAGinkgo Bioworks Holdings Inc. | 5,567 | $34K |
| LENZLENZ Therapeutics, Inc. | 2,432 | $22K |