| GILDGILEAD SCIENCES, INC. | 2,503,751 | $348.9M |
| REGNREGENERON PHARMACEUTICALS, INC. | 176,342 | $136.2M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 219,235 | $72.5M |
| INSMINSMED Inc | 360,075 | $58.9M |
| INCYIncyte Corp. | 289,697 | $27.3M |
| MRNAModerna, Inc. | 318,776 | $16.2M |
| TEVATeva Pharmaceutical Industries Limited | 410,453 | $12.4M |
| IONSIONIS PHARMACEUTICALS INC | 137,507 | $10.3M |
| EXELEXELIXIS, INC. | 233,213 | $10.0M |
| BBIOBridgeBio Pharma, Inc. | 133,572 | $9.9M |
| ROIVRoivant Sciences Ltd. | 351,869 | $9.7M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 172,285 | $9.7M |
| JAZZJazz Pharmaceuticals plc | 49,127 | $9.3M |
| RVMDREVOLUTION MEDICINES, INC. | 80,514 | $7.8M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 112,971 | $7.1M |
| CYTKCYTOKINETICS INC | 106,994 | $7.1M |
| PCVXVaxcyte, Inc. | 109,243 | $6.3M |
| AXSMAxsome Therapeutics, Inc. | 33,880 | $5.7M |
| PTGXProtagonist Therapeutics, Inc | 46,386 | $4.9M |
| TGTXTG THERAPEUTICS, INC. | 140,871 | $4.7M |
| PTCTPTC THERAPEUTICS, INC. | 65,200 | $4.4M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 49,689 | $4.3M |
| NUVLNuvalent, Inc. | 39,249 | $4.0M |
| FOLDAMICUS THERAPEUTICS, INC. | 256,224 | $3.7M |
| LGNDLigand Pharmaceuticals Incorporated | 17,432 | $3.5M |
| COGTCogent Biosciences, Inc. | 87,617 | $3.4M |
| SRRKScholar Rock Holding Corp | 64,617 | $3.2M |
| VKTXViking Therapeutics, Inc. | 95,650 | $3.1M |
| APLSApellis Pharmaceuticals, Inc. | 71,855 | $2.9M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 50,476 | $2.6M |
| ACADACADIA PHARMACEUTICALS INC | 114,112 | $2.5M |
| DNLIDenali Therapeutics Inc. | 125,243 | $2.4M |
| APGEApogee Therapeutics, Inc. | 25,656 | $2.2M |
| AGIOAGIOS PHARMACEUTICALS, INC. | 58,648 | $2.0M |
| TERNTerns Pharmaceuticals, Inc. | 37,267 | $2.0M |
| BEAMBeam Therapeutics Inc. | 80,697 | $1.9M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 22,884 | $1.9M |
| ADMAADMA BIOLOGICS, INC. | 212,469 | $1.9M |
| IBRXImmunityBio, Inc. | 241,057 | $1.8M |
| IMVTImmunovant, Inc. | 69,442 | $1.7M |
| ARQTArcutis Biotherapeutics, Inc. | 72,590 | $1.7M |
| SYRESpyre Therapeutics, Inc. | 33,232 | $1.7M |
| TVTXTravere Therapeutics, Inc. | 54,517 | $1.6M |
| LQDALiquidia Corp | 40,873 | $1.5M |
| INVAInnoviva, Inc. | 62,555 | $1.5M |
| OGNOrganon & Co. | 228,772 | $1.4M |
| CLDXCelldex Therapeutics, Inc. | 41,091 | $1.3M |
| RXRXRECURSION PHARMACEUTICALS, INC. | 421,368 | $1.3M |
| RCUSArcus Biosciences, Inc. | 55,908 | $1.2M |
| NKTRNEKTAR THERAPEUTICS | 15,916 | $1.1M |
| KNSAKiniksa Pharmaceuticals International, plc | 23,423 | $1.1M |
| DAWNDay One Biopharmaceuticals, Inc. | 50,545 | $1.1M |
| VCELVericel Corp | 33,660 | $1.1M |
| ADPTAdaptive Biotechnologies Corp | 77,561 | $1.1M |
| HRMYHarmony Biosciences Holdings, Inc. | 37,256 | $1.0M |
| NTLAIntellia Therapeutics, Inc. | 80,878 | $1.0M |
| IRONDisc Medicine, Inc. | 16,111 | $1.0M |
| DFTXDefinium Therapeutics Inc. | 54,018 | $1.0M |
| SLNOSOLENO THERAPEUTICS INC | 29,905 | $1.0M |
| ARDXARDELYX, INC. | 166,521 | $997K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 32,265 | $981K |
| ALMSALUMIS INC. | 42,244 | $931K |
| ELVNEnliven Therapeutics, Inc. | 23,050 | $904K |
| ANIPANI PHARMACEUTICALS INC | 11,738 | $903K |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 28,146 | $901K |
| OCULOCULAR THERAPEUTIX, INC | 104,362 | $884K |
| VRDNViridian Therapeutics, Inc.\DE | 43,571 | $852K |
| RLAYRelay Therapeutics, Inc. | 82,300 | $819K |
| STOKStoke Therapeutics, Inc. | 25,114 | $818K |
| PVLAPALVELLA THERAPEUTICS, INC. | 6,399 | $798K |
| BHVNBiohaven Ltd. | 89,018 | $753K |
| HROWHARROW, INC. | 21,295 | $751K |
| KODKodiak Sciences Inc. | 19,174 | $731K |
| NRIXNurix Therapeutics, Inc. | 46,564 | $722K |
| ORKAOruka Therapeutics, Inc. | 14,606 | $716K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 189,412 | $665K |
| ZYMEZymeworks Inc. | 26,279 | $658K |
| TNGXTango Therapeutics, Inc. | 29,604 | $619K |
| NUVBNuvation Bio Inc. | 143,580 | $616K |
| XERSXeris Biopharma Holdings, Inc. | 103,555 | $601K |
| CTMXCytomX Therapeutics, Inc. | 122,893 | $578K |
| SMMTSummit Therapeutics Inc. | 28,611 | $542K |
| ANABANAPTYSBIO, INC | 9,690 | $537K |
| ALVOAlvotech | 151,935 | $527K |
| BCAXBicara Therapeutics Inc. | 23,943 | $476K |
| GERNGERON CORP | 313,117 | $467K |
| PGENPRECIGEN, INC. | 117,077 | $453K |
| MLTXMoonLake Immunotherapeutics | 23,828 | $444K |
| ANNXAnnexon, Inc. | 79,486 | $440K |
| PHVSPharvaris N.V. | 15,060 | $425K |
| KURAKura Oncology, Inc. | 51,207 | $416K |
| QUREuniQure N.V. | 25,337 | $414K |
| ABUSArbutus Biopharma Corp | 89,582 | $403K |
| CMPXCompass Therapeutics, Inc. | 74,689 | $395K |
| ATAIAtai Beckley N.V. | 110,492 | $391K |
| OLMAOlema Pharmaceuticals, Inc. | 24,798 | $370K |
| ARVNARVINAS, INC. | 33,536 | $355K |
| KALVKalVista Pharmaceuticals, Inc. | 17,324 | $349K |
| OPKOPKO HEALTH, INC. | 294,013 | $335K |
| SPRYARS Pharmaceuticals, Inc. | 40,388 | $324K |
| ORICOric Pharmaceuticals, Inc. | 25,189 | $319K |
| SANASana Biotechnology, Inc. | 101,668 | $293K |
| CGEMCullinan Therapeutics, Inc. | 20,045 | $285K |
| SVRASavara Inc | 47,638 | $260K |
| PLSEPulse Biosciences Inc Common Stock (DE) | 11,602 | $250K |
| ZBIOZenas BioPharma, Inc. | 10,642 | $208K |
| FLGTFulgent Genetics Inc. | 11,796 | $188K |
| DNAGinkgo Bioworks Holdings Inc. | 24,059 | $147K |
| UPBUpstream Bio, Inc. | 9,250 | $83K |
| LENZLENZ Therapeutics, Inc. | 6,103 | $56K |
| RDYDR REDDYS LABORATORIES LTD | 105 | $1K |