| GILDGILEAD SCIENCES, INC. | 501,840 | $69.2M |
| REGNREGENERON PHARMACEUTICALS, INC. | 39,652 | $30.2M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 57,927 | $18.8M |
| EXELEXELIXIS, INC. | 382,343 | $16.4M |
| RVMDREVOLUTION MEDICINES, INC. | 137,242 | $13.2M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 210,633 | $11.5M |
| INSMINSMED Inc | 61,776 | $9.7M |
| BBIOBridgeBio Pharma, Inc. | 129,601 | $9.5M |
| COGTCogent Biosciences, Inc. | 231,569 | $8.9M |
| GRFSGrifols S.A. | 1,123,470 | $8.5M |
| INCYIncyte Corp. | 77,066 | $7.1M |
| SNYSanofi | 136,006 | $6.4M |
| NUVLNuvalent, Inc. | 53,415 | $5.5M |
| GMABGenmab A/S | 184,124 | $4.9M |
| MRNAModerna, Inc. | 97,031 | $4.8M |
| ONCBeOne Medicines Ltd. | 12,633 | $3.8M |
| JAZZJazz Pharmaceuticals plc | 19,413 | $3.6M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 47,830 | $3.0M |
| TEVATeva Pharmaceutical Industries Limited | 99,173 | $3.0M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 48,445 | $2.7M |
| ZYMEZymeworks Inc. | 104,931 | $2.6M |
| IONSIONIS PHARMACEUTICALS INC | 34,432 | $2.5M |
| ROIVRoivant Sciences Ltd. | 88,735 | $2.3M |
| SMMTSummit Therapeutics Inc. | 120,314 | $2.3M |
| ANABANAPTYSBIO, INC | 36,352 | $2.0M |
| RCUSArcus Biosciences, Inc. | 86,342 | $1.9M |
| ELVNEnliven Therapeutics, Inc. | 47,515 | $1.9M |
| NUVBNuvation Bio Inc. | 392,754 | $1.7M |
| IMTXImmatics N.V. | 170,389 | $1.7M |
| RLAYRelay Therapeutics, Inc. | 154,100 | $1.5M |
| OGNOrganon & Co. | 241,412 | $1.4M |
| CYTKCYTOKINETICS INC | 19,983 | $1.3M |
| VKTXViking Therapeutics, Inc. | 39,554 | $1.3M |
| OLMAOlema Pharmaceuticals, Inc. | 85,151 | $1.3M |
| PTGXProtagonist Therapeutics, Inc | 11,034 | $1.2M |
| CTMXCytomX Therapeutics, Inc. | 245,768 | $1.2M |
| HCMHUTCHMED (China) Limited | 67,385 | $1.0M |
| IMCRImmunocore Holdings plc | 30,651 | $924K |
| CGEMCullinan Therapeutics, Inc. | 62,421 | $887K |
| ARVNARVINAS, INC. | 83,581 | $886K |
| ARGXARGENX SE | 1,194 | $846K |
| FOLDAMICUS THERAPEUTICS, INC. | 52,382 | $757K |
| BBOTBridgeBio Oncology Therapeutics, Inc. | 82,172 | $735K |
| CMPXCompass Therapeutics, Inc. | 138,276 | $731K |
| ORICOric Pharmaceuticals, Inc. | 57,602 | $730K |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 22,458 | $719K |
| DAWNDay One Biopharmaceuticals, Inc. | 32,074 | $688K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 184,115 | $646K |
| AXSMAxsome Therapeutics, Inc. | 3,685 | $623K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 14,376 | $486K |
| SRRKScholar Rock Holding Corp | 9,791 | $481K |
| INVAInnoviva, Inc. | 18,253 | $425K |
| SLSSELLAS Life Sciences Group, Inc. | 90,007 | $381K |
| ORKAOruka Therapeutics, Inc. | 6,546 | $321K |
| KNSAKiniksa Pharmaceuticals International, plc | 6,184 | $298K |
| STOKStoke Therapeutics, Inc. | 8,540 | $278K |
| LQDALiquidia Corp | 6,859 | $259K |
| GPCRStructure Therapeutics Inc. | 4,643 | $224K |
| NTLAIntellia Therapeutics, Inc. | 14,076 | $180K |
| DRTSAlpha Tau Medical Ltd. | 25,093 | $177K |
| RDYDR REDDYS LABORATORIES LTD | 10,272 | $142K |
| XERSXeris Biopharma Holdings, Inc. | 18,159 | $105K |
| ATAIAtai Beckley N.V. | 15,574 | $55K |