| IONSIONIS PHARMACEUTICALS INC | 523,932 | $39.3M |
| GILDGILEAD SCIENCES, INC. | 257,022 | $35.8M |
| ANIPANI PHARMACEUTICALS INC | 220,224 | $16.9M |
| REGNREGENERON PHARMACEUTICALS, INC. | 21,477 | $16.6M |
| TEVATeva Pharmaceutical Industries Limited | 549,620 | $16.6M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 130,034 | $6.7M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 18,830 | $6.2M |
| INSMINSMED Inc | 30,382 | $5.0M |
| INVAInnoviva, Inc. | 200,082 | $4.7M |
| MRNAModerna, Inc. | 45,607 | $2.3M |
| INCYIncyte Corp. | 23,980 | $2.3M |
| RVMDREVOLUTION MEDICINES, INC. | 20,647 | $2.0M |
| EXELEXELIXIS, INC. | 33,046 | $1.4M |
| BBIOBridgeBio Pharma, Inc. | 18,731 | $1.4M |
| ROIVRoivant Sciences Ltd. | 48,711 | $1.3M |
| JAZZJazz Pharmaceuticals plc | 7,092 | $1.3M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 23,726 | $1.3M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 15,829 | $992K |
| CYTKCYTOKINETICS INC | 15,038 | $991K |
| PCVXVaxcyte, Inc. | 15,240 | $886K |
| AXSMAxsome Therapeutics, Inc. | 4,532 | $766K |
| PTGXProtagonist Therapeutics, Inc | 6,448 | $680K |
| TGTXTG THERAPEUTICS, INC. | 19,455 | $646K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 7,330 | $637K |
| PTCTPTC THERAPEUTICS, INC. | 9,353 | $637K |
| NUVLNuvalent, Inc. | 5,141 | $527K |
| FOLDAMICUS THERAPEUTICS, INC. | 36,103 | $522K |
| LGNDLigand Pharmaceuticals Incorporated | 2,548 | $509K |
| VKTXViking Therapeutics, Inc. | 13,904 | $452K |
| COGTCogent Biosciences, Inc. | 10,829 | $417K |
| SRRKScholar Rock Holding Corp | 8,049 | $396K |
| APLSApellis Pharmaceuticals, Inc. | 9,776 | $393K |
| TERNTerns Pharmaceuticals, Inc. | 7,378 | $389K |
| APGEApogee Therapeutics, Inc. | 4,201 | $354K |
| DNLIDenali Therapeutics Inc. | 17,882 | $343K |
| IBRXImmunityBio, Inc. | 44,708 | $343K |
| ACADACADIA PHARMACEUTICALS INC | 15,195 | $338K |
| ARQTArcutis Biotherapeutics, Inc. | 14,267 | $336K |
| TVTXTravere Therapeutics, Inc. | 10,896 | $324K |
| SYRESpyre Therapeutics, Inc. | 6,280 | $317K |
| LQDALiquidia Corp | 7,886 | $298K |
| BEAMBeam Therapeutics Inc. | 11,768 | $280K |
| ADMAADMA BIOLOGICS, INC. | 30,794 | $277K |
| IMVTImmunovant, Inc. | 10,368 | $258K |
| CLDXCelldex Therapeutics, Inc. | 7,756 | $246K |
| RCUSArcus Biosciences, Inc. | 11,224 | $242K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 7,127 | $241K |
| PHVSPharvaris N.V. | 8,176 | $231K |
| KNSAKiniksa Pharmaceuticals International, plc | 4,690 | $226K |
| NKTRNEKTAR THERAPEUTICS | 3,098 | $223K |
| VCELVericel Corp | 6,512 | $209K |
| OGNOrganon & Co. | 33,577 | $201K |
| IRONDisc Medicine, Inc. | 3,144 | $201K |
| DFTXDefinium Therapeutics Inc. | 10,300 | $195K |
| ARDXARDELYX, INC. | 31,120 | $186K |
| NTLAIntellia Therapeutics, Inc. | 14,183 | $182K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 57,464 | $176K |
| OCULOCULAR THERAPEUTIX, INC | 20,624 | $175K |
| BHVNBiohaven Ltd. | 16,787 | $142K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 39,610 | $139K |
| NUVBNuvation Bio Inc. | 28,849 | $124K |
| XERSXeris Biopharma Holdings, Inc. | 21,122 | $123K |
| GERNGERON CORP | 62,093 | $93K |
| PGENPRECIGEN, INC. | 23,009 | $89K |
| ABUSArbutus Biopharma Corp | 18,647 | $84K |
| ANNXAnnexon, Inc. | 15,099 | $84K |
| CMPXCompass Therapeutics, Inc. | 14,464 | $77K |
| ATAIAtai Beckley N.V. | 21,559 | $76K |
| SANASana Biotechnology, Inc. | 22,492 | $65K |
| CTMXCytomX Therapeutics, Inc. | 11,467 | $54K |