| GILDGILEAD SCIENCES, INC. | 3,372,079 | $470.0M |
| REGNREGENERON PHARMACEUTICALS, INC. | 350,923 | $271.1M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 281,848 | $93.3M |
| ARGXARGENX SE | 80,824 | $59.0M |
| IONSIONIS PHARMACEUTICALS INC | 529,954 | $39.8M |
| RVMDREVOLUTION MEDICINES, INC. | 317,811 | $30.9M |
| CYTKCYTOKINETICS INC | 420,846 | $27.7M |
| INSMINSMED Inc | 163,424 | $26.7M |
| ROIVRoivant Sciences Ltd. | 715,282 | $19.8M |
| PTGXProtagonist Therapeutics, Inc | 183,700 | $19.4M |
| PCVXVaxcyte, Inc. | 312,762 | $18.2M |
| SMMTSummit Therapeutics Inc. | 956,894 | $18.1M |
| APGEApogee Therapeutics, Inc. | 184,792 | $15.6M |
| NUVLNuvalent, Inc. | 137,764 | $14.1M |
| INCYIncyte Corp. | 142,983 | $13.5M |
| SRRKScholar Rock Holding Corp | 223,064 | $11.0M |
| BBIOBridgeBio Pharma, Inc. | 136,502 | $10.1M |
| GPCRStructure Therapeutics Inc. | 204,762 | $9.9M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 116,576 | $9.8M |
| CNTACentessa Pharmaceuticals plc | 242,044 | $9.6M |
| MRNAModerna, Inc. | 179,583 | $9.1M |
| TEVATeva Pharmaceutical Industries Limited | 253,661 | $7.6M |
| ABVXAbivax SA | 65,548 | $7.3M |
| SYRESpyre Therapeutics, Inc. | 137,390 | $6.9M |
| TENXTENAX THERAPEUTICS, INC. | 399,184 | $6.4M |
| KODKodiak Sciences Inc. | 162,298 | $6.2M |
| BCAXBicara Therapeutics Inc. | 269,718 | $5.4M |
| DNLIDenali Therapeutics Inc. | 255,766 | $4.9M |
| TERNTerns Pharmaceuticals, Inc. | 89,594 | $4.7M |
| IMTXImmatics N.V. | 470,444 | $4.6M |
| AXSMAxsome Therapeutics, Inc. | 27,132 | $4.6M |
| ALMSALUMIS INC. | 191,202 | $4.2M |
| BEAMBeam Therapeutics Inc. | 176,024 | $4.2M |
| IMCRImmunocore Holdings plc | 135,828 | $4.1M |
| ORKAOruka Therapeutics, Inc. | 75,696 | $3.7M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 38,778 | $3.4M |
| SIONSionna Therapeutics, Inc. | 82,996 | $3.3M |
| ORICOric Pharmaceuticals, Inc. | 258,602 | $3.3M |
| IMVTImmunovant, Inc. | 131,352 | $3.3M |
| ONCBeOne Medicines Ltd. | 10,014 | $3.0M |
| NRIXNurix Therapeutics, Inc. | 189,250 | $2.9M |
| PVLAPALVELLA THERAPEUTICS, INC. | 22,746 | $2.8M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 44,720 | $2.8M |
| MLTXMoonLake Immunotherapeutics | 142,706 | $2.7M |
| STOKStoke Therapeutics, Inc. | 74,400 | $2.4M |
| CLDXCelldex Therapeutics, Inc. | 70,292 | $2.2M |
| TNGXTango Therapeutics, Inc. | 102,600 | $2.1M |
| RLAYRelay Therapeutics, Inc. | 214,170 | $2.1M |
| COGTCogent Biosciences, Inc. | 52,590 | $2.0M |
| OCULOCULAR THERAPEUTIX, INC | 238,000 | $2.0M |
| IRONDisc Medicine, Inc. | 30,476 | $1.9M |
| CLYMClimb Bio, Inc. | 250,102 | $1.7M |
| CGEMCullinan Therapeutics, Inc. | 114,400 | $1.6M |
| OLMAOlema Pharmaceuticals, Inc. | 106,214 | $1.6M |
| LQDALiquidia Corp | 41,944 | $1.6M |
| PHVSPharvaris N.V. | 54,826 | $1.5M |
| BHVNBiohaven Ltd. | 177,390 | $1.5M |
| RNAAtrium Therapeutics Inc. | 111,200 | $1.5M |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 340,252 | $1.2M |
| VRDNViridian Therapeutics, Inc.\DE | 55,386 | $1.1M |
| MPLTMapLight Therapeutics, Inc. | 47,768 | $971K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 23,732 | $803K |
| AVTXAvalo Therapeutics, Inc. | 51,408 | $768K |
| TRDAEntrada Therapeutics, Inc. | 53,588 | $676K |
| TECXTectonic Therapeutic, Inc. | 20,400 | $631K |
| TVTXTravere Therapeutics, Inc. | 17,534 | $521K |
| BBOTBridgeBio Oncology Therapeutics, Inc. | 57,572 | $515K |
| IMMXImmix Biopharma, Inc. | 53,200 | $485K |
| BCYCBICYCLE THERAPEUTICS PLC | 91,992 | $427K |
| ADPTAdaptive Biotechnologies Corp | 30,670 | $426K |
| BDTXBlack Diamond Therapeutics, Inc. | 195,930 | $417K |
| ELVNEnliven Therapeutics, Inc. | 8,600 | $337K |
| RCKTRocket Pharmaceuticals Inc. | 68,046 | $244K |
| LENZLENZ Therapeutics, Inc. | 24,610 | $225K |
| NUVBNuvation Bio Inc. | 30,462 | $131K |
| ANNXAnnexon, Inc. | 22,760 | $126K |
| DNAGinkgo Bioworks Holdings Inc. | 13,046 | $80K |