| GILDGILEAD SCIENCES, INC. | 1,202,321 | $167.6M |
| BHVNBiohaven Ltd. | 9,940,885 | $84.1M |
| REGNREGENERON PHARMACEUTICALS, INC. | 48,907 | $37.8M |
| SNYSanofi | 783,348 | $37.7M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 621,987 | $34.3M |
| JAZZJazz Pharmaceuticals plc | 139,514 | $26.4M |
| MANEVeradermics Incorporated | 294,117 | $18.6M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 49,954 | $16.5M |
| IONSIONIS PHARMACEUTICALS INC | 196,703 | $14.8M |
| NTLAIntellia Therapeutics, Inc. | 1,012,706 | $13.0M |
| INSMINSMED Inc | 75,702 | $12.4M |
| VKTXViking Therapeutics, Inc. | 340,521 | $11.1M |
| HROWHARROW, INC. | 234,660 | $8.3M |
| LGNDLigand Pharmaceuticals Incorporated | 33,017 | $6.6M |
| TEVATeva Pharmaceutical Industries Limited | 207,595 | $6.3M |
| ARGXARGENX SE | 8,069 | $5.9M |
| ALMSALUMIS INC. | 209,729 | $4.6M |
| INCYIncyte Corp. | 43,577 | $4.1M |
| CYTKCYTOKINETICS INC | 54,444 | $3.6M |
| ONCBeOne Medicines Ltd. | 11,469 | $3.4M |
| RGNXREGENXBIO Inc. | 392,769 | $3.3M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 60,539 | $3.1M |
| ROIVRoivant Sciences Ltd. | 89,539 | $2.5M |
| MRNAModerna, Inc. | 48,317 | $2.5M |
| RXRXRECURSION PHARMACEUTICALS, INC. | 776,928 | $2.4M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 39,149 | $2.2M |
| GMABGenmab A/S | 79,105 | $2.1M |
| GRFSGrifols S.A. | 263,243 | $2.1M |
| ZYMEZymeworks Inc. | 76,756 | $1.9M |
| VCELVericel Corp | 52,927 | $1.7M |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 449,639 | $1.6M |
| KNSAKiniksa Pharmaceuticals International, plc | 31,951 | $1.5M |
| EXELEXELIXIS, INC. | 35,544 | $1.5M |
| TGTXTG THERAPEUTICS, INC. | 45,142 | $1.5M |
| AQSTAquestive Therapeutics, Inc. | 359,903 | $1.5M |
| ABVXAbivax SA | 10,777 | $1.2M |
| OGNOrganon & Co. | 197,452 | $1.2M |
| APLSApellis Pharmaceuticals, Inc. | 28,220 | $1.1M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 12,339 | $1.1M |
| AXSMAxsome Therapeutics, Inc. | 5,920 | $1.0M |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 29,221 | $935K |
| ANIPANI PHARMACEUTICALS INC | 10,771 | $828K |
| QUREuniQure N.V. | 47,084 | $770K |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 11,696 | $733K |
| AVXLANAVEX LIFE SCIENCES CORP. | 236,804 | $727K |
| BDTXBlack Diamond Therapeutics, Inc. | 278,645 | $594K |
| PGENPRECIGEN, INC. | 151,386 | $586K |
| GPCRStructure Therapeutics Inc. | 11,342 | $547K |
| ALTAltimmune, Inc. | 134,616 | $415K |
| TERNTerns Pharmaceuticals, Inc. | 7,148 | $377K |
| COGTCogent Biosciences, Inc. | 9,340 | $359K |
| RDYDR REDDYS LABORATORIES LTD | 25,869 | $358K |
| BBIOBridgeBio Pharma, Inc. | 4,573 | $340K |
| IMCRImmunocore Holdings plc | 11,222 | $338K |
| TVTXTravere Therapeutics, Inc. | 10,525 | $313K |
| ELVNEnliven Therapeutics, Inc. | 7,924 | $311K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 10,137 | $308K |
| ORICOric Pharmaceuticals, Inc. | 23,899 | $303K |
| ORKAOruka Therapeutics, Inc. | 6,156 | $302K |
| BEAMBeam Therapeutics Inc. | 12,415 | $296K |
| ABCLAbCellera Biologics Inc. | 84,544 | $295K |
| ACADACADIA PHARMACEUTICALS INC | 12,148 | $270K |
| ADMAADMA BIOLOGICS, INC. | 26,931 | $243K |
| DFTXDefinium Therapeutics Inc. | 12,626 | $239K |
| APGEApogee Therapeutics, Inc. | 2,814 | $237K |
| FOLDAMICUS THERAPEUTICS, INC. | 13,459 | $195K |
| ARDXARDELYX, INC. | 27,055 | $162K |
| CMPSCOMPASS Pathways plc | 29,000 | $160K |
| ALVOAlvotech | 42,576 | $146K |
| CMPXCompass Therapeutics, Inc. | 27,497 | $145K |
| RCKTRocket Pharmaceuticals Inc. | 34,356 | $123K |
| XFORX4 Pharmaceuticals, Inc | 21,789 | $90K |
| BCYCBICYCLE THERAPEUTICS PLC | 14,687 | $68K |
| ABEOABEONA THERAPEUTICS INC. | 13,975 | $63K |
| CUECue Biopharma, Inc. | 246,556 | $57K |
| SLSSELLAS Life Sciences Group, Inc. | 11,536 | $49K |
| GERNGERON CORP | 14,836 | $22K |
| OPKOPKO HEALTH, INC. | 15,549 | $18K |